Managing Burning Mouth Syndrome With Amitriptyline and Multiwave Locked System Laser Therapy: A Case Report.

Background: Burning mouth syndrome (BMS) is a chronic condition marked by oral pain without visible signs, often associated with neuropathic pain and psychological factors. Its complex and multifactorial nature makes complete symptom relief difficult to achieve.

Case report: A 72-year-old woman with a 15-year history of burning sensations on her tongue and gums, along with dry mouth, was diagnosed with BMS after ruling out other conditions. Previous treatments, including medication adjustments and physical therapy during inpatient care, were unsuccessful in improving her symptoms.

Conclusions: Amitriptyline was introduced with a gradually increasing dose, and multiwave locked system laser therapy was applied daily to the painful areas of the tongue for 12 sessions. Following 2 weeks of treatment, as well as at the one-month and three-month follow-up postdischarge, a significant reduction in pain was observed. To the best of our knowledge, this treatment combination has not been previously explored, making this an area of interest for future research.