Biopsychosocial science and medicine最新文献

{"title":"The Immediate Effects of a Resonant Breathing Exercise on Adolescents' Stress Responses: A Randomized Trial.","authors":"Nathalie Michels, Marie-Anne Vanderhasselt, Jolien Braet, Janne Vreye, Riet Vergauwe, Jente Depoorter, Matteo Giletta","doi":"10.1097/PSY.0000000000001448","DOIUrl":"10.1097/PSY.0000000000001448","url":null,"abstract":"<p><strong>Objective: </strong>This single-blind randomized controlled laboratory experiment investigated the impact of resonant breathing on adolescents' autonomic nervous system (ANS) and affective responses to a standardized acute stressor.</p><p><strong>Methods: </strong>Adolescents ( n = 150, aged 12 to 13 years, 40% boys) were randomized into 2 conditions: resonant breathing (RB condition) or spontaneous breathing (active control condition), both with visual guidance. In this registered report ( https://osf.io/8swdp ), mixed-effects models compared conditions on cardiac ANS (heart rate variability RMSSD, preejection period PEP) and affective responses (positive and negative affect) to the trier social stress test, across reactivity and recovery phases. In addition, conditions were compared on rumination and reappraisal use.</p><p><strong>Results: </strong>The determined resonant rate showed a narrow interquartile range (6.2 to 6.7 breaths/min) and proved difficult to sustain during the 10-minute exercise. The RB intervention significantly reduced breathing rate (Cohen d = -4.69) and increased RMSSD during the breathing phase ( d = 1.68). Compared with the control condition, PEP reactivity to the stressor was attenuated in the RB condition ( d = 0.32), supporting a protective effect. Unexpectedly, RMSSD stress reactivity was more pronounced in the RB condition ( d = -1.37), though this effect diminished in sensitivity analyses, suggesting regression to the mean. Exploratory analyses indicated that among adolescents with lower trait stress-related symptoms, RB reduced RMSSD stress reactivity relative to baseline ( d = 0.75). No differences between conditions were found in affective responses, emotion regulation, or stress recovery.</p><p><strong>Conclusions: </strong>The findings only partially support the hypothesis that RB buffers physiological stress reactivity, with no observed effects on affect or recovery. Repeated training may be essential for achieving the resonant rate and potentially enhancing stress-buffering capacity.</p>","PeriodicalId":520402,"journal":{"name":"Biopsychosocial science and medicine","volume":" ","pages":"166-178"},"PeriodicalIF":0.0,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145553076","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Perceived Discrimination and Immunological Aging: A Systematic Review of Cellular and Molecular Markers.","authors":"Adolfo G Cuevas, Emiko Kranz, Mariana Rodrigues, Ariel Binns, Gabrielle Martin, Natalie Herz, Alisha A Crump, Jemar R Bather, Steven W Cole","doi":"10.1097/PSY.0000000000001452","DOIUrl":"10.1097/PSY.0000000000001452","url":null,"abstract":"<p><strong>Objective: </strong>Perceived discrimination is a chronic social stressor that increases the risk of disease. While prior research has linked discrimination to adverse biological health outcomes, the cellular and molecular mechanisms underlying these associations remain understudied.</p><p><strong>Methods: </strong>We conducted a systematic review and identified 32 empirical studies that met the inclusion criteria examining the relationship between self-reported discrimination experiences and markers of immunological aging, focusing on telomere length, gene expression profiles, and immune cell composition.</p><p><strong>Results: </strong>Findings consistently showed discrimination to be associated with accelerated telomere shortening; altered transcriptional activity, particularly within proinflammatory and antiviral pathways aligned with the Conserved Transcriptional Response to Adversity; and shifts in immune cell populations indicative of immune aging and heightened inflammatory activity. Despite this growing evidence, the dominance of cross-sectional designs, limited racial/ethnic diversity in study populations, and narrow focus on select immune markers restrict generalizability and mechanistic clarity.</p><p><strong>Conclusion: </strong>We emphasize the need for longitudinal research, broader immune phenotyping, and rigorous modeling of behavioral and physiological mediators to elucidate how discrimination drives chronic immune dysregulation. Advancing this field is essential for understanding the biopsychosocial pathways linking discrimination to disease.</p>","PeriodicalId":520402,"journal":{"name":"Biopsychosocial science and medicine","volume":" ","pages":"137-155"},"PeriodicalIF":0.0,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13134768/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145553054","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association of Marital Status With All-cause and Cause-specific Mortality in Women and Men From the Moli-sani Study Cohort.","authors":"Anwal Ghulam, Augusto Di Castelnuovo, Simona Costanzo, Francesco Gianfagna, Amalia De Curtis, Chiara Cerletti, Maria Benedetta Donati, Giovanni de Gaetano, Licia Iacoviello, Marialaura Bonaccio","doi":"10.1097/PSY.0000000000001454","DOIUrl":"10.1097/PSY.0000000000001454","url":null,"abstract":"<p><strong>Objective: </strong>To study the relationship between marital status and all-cause and cause-specific mortality in Italian women and men, and to further analyse the role of potential mediating factors such as socioeconomic (eg, number of cohabitants, education, housing), behavioural (eg, smoking, leisure time physical activity, BMI), and physiological factors (eg, blood glucose, lipid levels).</p><p><strong>Methods: </strong>We conducted longitudinal analyses on 12,139 women and 11,166 men from the Moli-sani study: exposure and mediation variables were collected only at baseline (2005-2010), while participants were followed up for vital status for 14.5 years (IQR: 12.2 to 17.3; median). Marital status was categorized as married/cohabiting, divorced/separated, single/unmarried, or widowed. Mortality outcomes included all-cause, cardiovascular, cancer, and other causes. Mediation analyses examined explanatory mechanisms, and subgroup analyses evaluated generational differences.</p><p><strong>Results: </strong>Compared with married/cohabiting, single women showed elevated rates for all-cause and cancer mortality (HR = 1.33; 95% CI = 1.04-1.69 and HR = 1.92; 95% CI = 1.32-2.79, respectively). All men in unmarried categories faced higher mortality rates for all-cause mortality as compared with married/cohabiting (HR = 2.03; 95% CI = 1.51-2.72, HR = 1.40; 95% CI = 1.09-1.81, HR = 1.32; 95% CI = 1.11-1.56), for divorced/separated, single, and widowed, respectively. Mediation analyses revealed that smoking, cystatin C levels, and heart rate were relevant mediating factors for single women, divorced/separated men, and single men. While behavioural factors like leisure time, physical activity, diet quality, and heart rate played significant role in widowed men.</p><p><strong>Conclusions: </strong>Single women and all unmarried categories in men face significantly elevated rates of mortality. Part of these associations was explained by behavioural and physiological factors.</p>","PeriodicalId":520402,"journal":{"name":"Biopsychosocial science and medicine","volume":"88 2","pages":"229-244"},"PeriodicalIF":0.0,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146121676","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Parental Resilience Resources and Gestational Length: A Test of Prenatal Maternal Inflammatory Mediation.","authors":"Kavya Swaminathan, Christine Guardino, Haiyan Liu, Christine Dunkel Schetter, Jennifer Hahn-Holbrook","doi":"10.1097/PSY.0000000000001445","DOIUrl":"10.1097/PSY.0000000000001445","url":null,"abstract":"<p><strong>Objective: </strong>Adverse birth outcomes such as preterm birth and low birthweight can engender long-term developmental consequences for the health and well-being of offspring. Prior research demonstrates that chronic inflammation during pregnancy in women increases the risk of both birth and developmental adversities. However, little research has investigated whether protective factors like psychological resilience resources predict lower maternal inflammation in pregnancy and decrease the risk of preterm birth and infant low birth weight.</p><p><strong>Methods: </strong>In this study, we tested whether resilience resources measured in mothers and fathers predicted longer gestational length and higher birthweight through lower levels of systemic inflammation operationalized as C-reactive protein (CRP) in a sample of 217 parent dyads from the Community Child Health Network (CCHN) study. We also explored whether these effects varied by parental marital status. Resilience resources were conceptualized as a latent factor composed of social support, self-esteem, mastery, and optimism. We then tested a 2-stage latent moderated-mediation model followed by a multigroup structural equation model.</p><p><strong>Results: </strong>We found that paternal resilience resources predicted lower prenatal maternal CRP ( β =-0.39 , p =.009, SE=0.05), which in turn predicted a longer gestational length in married ( β =-0.41, p =.042, SE=0.53) but not unmarried parents, whether cohabiting or not. Maternal resilience resources did not directly predict CRP or birth outcomes.</p><p><strong>Conclusions: </strong>This research suggests that a combination of 4 resilience resources among fathers in married couples may be protective for maternal health.</p>","PeriodicalId":520402,"journal":{"name":"Biopsychosocial science and medicine","volume":" ","pages":"245-256"},"PeriodicalIF":0.0,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12704204/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145461136","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Ecologically Assessed Sleep Duration and Pulse Wave Velocity in Young Adult African Americans.","authors":"Paul P Sheriff, Kevin Boyd, Pewu Lavela, Ishaan Sandhu, Thomas A Mellman","doi":"10.1097/PSY.0000000000001455","DOIUrl":"10.1097/PSY.0000000000001455","url":null,"abstract":"<p><strong>Objective: </strong>To investigate the association between arterial stiffness and sleep duration in young African American adults in an ecologically valid context.</p><p><strong>Methods: </strong>This study included 68 young adults (ages 18 to 35) who identified as African American. The average age of the sample was 28.4.±4.3 years and 38 (53.5%) were men. The average body mass index was in the healthy range and average insomnia severity was mild. Sleep was measured using actigraphy, and the time of lights out and awakenings were assessed using digital devices in participants' habitual environments. Pulse wave velocity (PWV) and central systolic pressure (CSP) were measured using the SphygmoCor CVO system in participants' homes in the morning, close to awakening from the last assessed sleep period.</p><p><strong>Results: </strong>PWV was significantly negatively correlated with total sleep time ( r =-0.26, p =.04); whereas CSP was correlated with age ( r =0.33, p =.003) and BMI ( r =0.28, p =.01) but not with any sleep measures. The results of a regression model indicated that the effect of total sleep time on PWV was accounted for by the males in the sample.</p><p><strong>Conclusion: </strong>Our results are consistent with a recent finding utilizing central augmentation indices during sleep regarding a relationship between sleep duration and arterial elasticity; however, we found the opposite relationship to gender. Replication and extension of these findings would add to the support for recognizing sleep duration as a modifiable risk factor for improving CV health.</p>","PeriodicalId":520402,"journal":{"name":"Biopsychosocial science and medicine","volume":" ","pages":"200-205"},"PeriodicalIF":0.0,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145893562","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Community Socioeconomic Disadvantage Relates to White Matter Hyperintensity Burden in Mid-to-Late Life Adults.","authors":"Anna L Marsland, Minjie Wu, Mia K DeCataldo, Howard J Aizenstein, Jinghang Li, Tamer S Ibrahim, Stephen B Manuck, Peter J Gianaros","doi":"10.1097/PSY.0000000000001453","DOIUrl":"10.1097/PSY.0000000000001453","url":null,"abstract":"<p><strong>Objective: </strong>Residing in communities characterized by socioeconomic disadvantage may confer risk for neurodegenerative brain changes and future neuropathology. Based on prior evidence, this study tested the hypotheses that (1) community-level disadvantage would relate independently of individual-level socioeconomic position to white matter hyperintensities (WMHs), which reflect subclinical brain pathology that may presage later dementia; and (2) this association would be partly explained by blood pressure, cardiometabolic risk, and/or systemic levels of inflammation. These hypotheses were examined among otherwise healthy middle-aged and older adults without clinical dementia at testing.</p><p><strong>Methods: </strong>Participants were 388 adults aged 40 to 72 years (53% female; 12% non-White) whose street addresses were entered into the Neighborhood Atlas to compute Area Deprivation Index scores by census block. Participants also underwent high-resolution (7 T) brain imaging to assess total WMH volume normalized for intracranial volume, and assessment of blood pressure, cardiometabolic (adiposity, lipids, glucose and insulin), and inflammatory (interleukin-6 and C-reactive protein) risk factors.</p><p><strong>Results: </strong>Linear regression models showed that higher community deprivation on the ADI was associated with greater WMH volume, independently of age, sex, years of education, smoking, and time between study visits (beta=0.11, p =.028). This association was largely independent of blood pressure, cardiometabolic risk, and systemic inflammation.</p><p><strong>Conclusions: </strong>The present novel findings add to growing evidence that community disadvantage relates to preclinical neurodegenerative changes, which may contribute to accelerated brain and cognitive aging. Future work is warranted to better understand pathways that link residential environments to brain health and to identify targets for community and public policy interventions.</p>","PeriodicalId":520402,"journal":{"name":"Biopsychosocial science and medicine","volume":" ","pages":"156-165"},"PeriodicalIF":0.0,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12875623/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145553073","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Differential Effects of Body Posture on Biological and Psychological Responses in the Trier Social Stress Test.","authors":"Miriam Kurz, Luca Abel, Felicitas Burkhardt, Robert Richer, Veronika Ringgold, Lena Schindler-Gmelch, Bjoern M Eskofier, Nicolas Rohleder","doi":"10.1097/PSY.0000000000001450","DOIUrl":"10.1097/PSY.0000000000001450","url":null,"abstract":"<p><strong>Objective: </strong>Acute stress protocols are important tools for laboratory research on acute stress mechanisms. Several reasons necessitate varying body posture. However, the effect of such variations has not been systematically studied. We therefore examined the impact of body posture (sitting vs. standing) on biological and psychological stress responses induced by the Trier Social Stress Test (TSST) and its control condition (friendly TSST; f-TSST).</p><p><strong>Methods: </strong>One hundred four participants (57.69% female, mean age: 22.28, SD = 3.44) were randomly assigned to the sitting versus standing group and underwent the TSST and f-TSST on 2 separate days in randomized order. Stress responses were measured through salivary cortisol and alpha-amylase, HR, HRV, and self-reports.</p><p><strong>Results: </strong>Biological stress responses were higher in the TSST condition and the standing group (eg, maximum cortisol increase: p = .004). Psychological stress response was higher in the stress condition (eg, negative affect : p < .001), but was not different between posture groups (eg, negative affect : p = .819). No differences were observed in any markers after adjusting the stress-response measures for the non-stress condition (smallest p = .173).</p><p><strong>Conclusions: </strong>Although biological, but not psychological stress responses were affected by body posture overall, these effects did not persist when responses in the stress condition were adjusted by subtracting the non-stress values from the f-TSST. This implies that the effect of body posture can be neglected in studies with a non-stress control condition, but that its effects should be taken into account in studies with only the stress protocol.</p>","PeriodicalId":520402,"journal":{"name":"Biopsychosocial science and medicine","volume":" ","pages":"179-190"},"PeriodicalIF":0.0,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12875627/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145553107","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Posttraumatic Stress Disorder and Increased Incidence of Cardiovascular Disease: Independent Effects and Moderation of Risk by Comorbidities, Sex, and Age.","authors":"David S Krantz, Frances H Gabbay, Elizabeth A Belleau, Pablo A Aliaga, Gary H Wynn, Murray B Stein, Robert J Ursano, James A Naifeh","doi":"10.1097/PSY.0000000000001442","DOIUrl":"10.1097/PSY.0000000000001442","url":null,"abstract":"<p><strong>Objective: </strong>Posttraumatic stress disorder (PTSD) is associated with increased risk of cardiovascular disease (CVD) and multiple comorbidities. We evaluated whether comorbidities, sex, or age modify PTSD-related risk of hypertension or atherosclerotic CVD (ASCVD).</p><p><strong>Methods: </strong>Associations of PTSD, comorbidities (metabolic and behavioral risk factors, depression, and sleep disorders), sex, and age (<40 vs ≥40 years) with incident hypertension and ASCVD were assessed in a large sample of US Army soldiers (86.2% male; 93.7% age <40). Discrete-time survival analyses of medical record ICD codes compared all person-months with initial hypertension diagnosis ( n = 49,656 cases) to an equal-probability sample of control person-months. Parallel analyses were conducted for ASCVD (CAD, MI, stroke, heart failure; n = 2427 person-months).</p><p><strong>Results: </strong>In univariate models, PTSD predicted subsequent hypertension [OR = 3.0 (95% CI = 2.9-3.1)] and ASCVD [OR = 2.7 (95% CI = 2.2-3.3)]. Associations remained significant adjusting for comorbidities and sociodemographic/service-related variables [hypertension: OR = 1.9 (95% CI = 1.8-2.0); ASCVD: OR = 1.4 (95% CI = 1.2-1.8)]. Sex, age, and each comorbidity independently predicted hypertension, and PTSD interacted with sex, age, metabolic risk factors, depression, and sleep disorders. Stratification indicated stronger PTSD-hypertension associations among men, and among those: aged younger than 40, without metabolic risk factors, without depression, and without sleep disorders. Standardized risk estimates for hypertension were higher among those with versus without PTSD, with versus without each comorbidity, among men, and among those aged 40 years or older. Comorbidities and age independently predicted ASCVD, but did not modify PTSD-ASCVD associations.</p><p><strong>Conclusions: </strong>PTSD and comorbidities independently predict hypertension and ASCVD, and sex, age, and comorbidities modify PTSD-hypertension relationships, thus suggesting that preventive interventions address both PTSD and comorbidities.</p>","PeriodicalId":520402,"journal":{"name":"Biopsychosocial science and medicine","volume":" ","pages":"206-216"},"PeriodicalIF":0.0,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12549015/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145202803","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Testing the Daily Bidirectional Relationships Between Stress and Sleep Using Bivariate Multilevel Autoregressive Modeling.","authors":"Connor Nicholls, Kimberley Shoaf, Tanya Halliday, Aric A Prather, Brian R W Baucom, Kelly Glazer Baron","doi":"10.1097/PSY.0000000000001446","DOIUrl":"10.1097/PSY.0000000000001446","url":null,"abstract":"<p><strong>Objective: </strong>Previous studies have demonstrated that stress and sleep are bidirectional and perseverative cognition (ie, worry and rumination) is a key cognitive mechanism in this relationship. The goal of our study was to examine the relationships between stress and sleep, and test whether physical activity moderates the stress-sleep link.</p><p><strong>Methods: </strong>Participants aged 18 and above were recruited from May 2020 to November 2021 and completed questionnaires and 7 days of twice daily text-based surveys, morning and evening. Morning text-based surveys assessed evening/overnight perseverative cognition and sleep, and evening surveys assessed daily stress ratings. Habitual physical activity was measured by the International Physical Activity Questionnaire. Analyses were conducted using bivariate multilevel autoregressive modeling (ML-VAR), a discrete-time structural equation model (SEM), to test relationships between repeated daily measures of sleep (duration/efficiency), stress, and preservative cognition, which were adjusted for age, sex, and race/ethnicity.</p><p><strong>Results: </strong>We obtained data from 155 participants (age M =42, SD=15, 82 f) over 1009 days. In the models, 95% credibility intervals for both stress (95% CI=-0.7, -0.1) and perseverative cognition (95% CI=-13.3, -6) showed they predicted shorter sleep duration during the corresponding night. Perseverative cognition had a stronger relationship with sleep duration than stress, but did not mediate its relationship. Participants with higher habitual MVPA had a weaker relationship between stress and sleep duration (95% CI=<0.001, 0.015). Perseverative cognition also predicted lower sleep efficiency that night (95% CI=-0.024, -0.006). There were no significant mediators or moderators in models of sleep efficiency.</p><p><strong>Conclusions: </strong>Results demonstrated that stress and perseverative cognition had a stronger impact on sleep at night than the opposite direction. In addition, results highlight the importance of physical activity in mitigating the deleterious effects of stress.</p>","PeriodicalId":520402,"journal":{"name":"Biopsychosocial science and medicine","volume":" ","pages":"191-199"},"PeriodicalIF":0.0,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145461144","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Emotion Regulation and Well-Being in Adults With Congenital Heart Disease.","authors":"Anna-Lena Ehmann, Paul C Helm, Ulrike M Bauer, Sven Barnow, Luise Pruessner","doi":"10.1097/PSY.0000000000001451","DOIUrl":"10.1097/PSY.0000000000001451","url":null,"abstract":"<p><strong>Objective: </strong>Congenital heart disease (CHD) is associated with daily stressors, including medical and physical limitations, as well as reduced social participation, necessitating psychological adjustment. Emotion regulation may be a key factor in this process and could explain variability in life satisfaction among individuals with CHD. However, emotion regulation has not been systematically investigated in this population.</p><p><strong>Methods: </strong>A total of 1187 adults (aged 18 to 85; 60.2% female) from the German National Register for Congenital Heart Defects were classified into simple, moderate, or complex CHD severity groups and completed self-report measures of emotion regulation, mental and general health, and life satisfaction.</p><p><strong>Results: </strong>Rumination, suppression, and avoidance were negatively associated with life satisfaction, mental health, and general health, whereas reappraisal, acceptance, problem solving, and social support showed positive associations (life satisfaction: r =-0.20 to 0.34, p <.001; mental health: r =-0.38 to 0.28, p =.19 to<.001; general health: r =-0.10 to 0.16, p =.19 to<.001). Simple slope analyses indicated that rumination predicted poorer general health at simple and moderate, but not complex, severity levels, when controlling for age, sex, relationship, and employment status. Suppression ability was linked to better general health only in complex CHD.</p><p><strong>Conclusions: </strong>Emotion regulation seems to be a critical factor in well-being outcomes among individuals with CHD. Findings highlight the importance of addressing emotion regulation skills in psychological interventions for this population.</p>","PeriodicalId":520402,"journal":{"name":"Biopsychosocial science and medicine","volume":"88 2","pages":"217-228"},"PeriodicalIF":0.0,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146121700","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}