Biopsychosocial science and medicine最新文献

{"title":"Article Summaries for July/August 2025 Biopsychosocial Science and Medicine, Volume 87, Issue 6.","authors":"","doi":"10.1097/PSY.0000000000001417","DOIUrl":"10.1097/PSY.0000000000001417","url":null,"abstract":"","PeriodicalId":520402,"journal":{"name":"Biopsychosocial science and medicine","volume":"87 6","pages":"353-354"},"PeriodicalIF":0.0,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144562578","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Spirit and Sense: Autonomic Response to Integrative Medicine Intervention for Health Care Personnel During Wartime.","authors":"Sameer Kassem, Jan Vagedes, Orit Gressel, Noah Samuels, Shir Elias, Eran Ben-Arye","doi":"10.1097/PSY.0000000000001402","DOIUrl":"10.1097/PSY.0000000000001402","url":null,"abstract":"<p><strong>Objective: </strong>The war in Israel placed health care providers (HCPs) under intense emotional and physical stress. HCPs referred to an integrative medicine (IM) intervention that underwent heart rate variability (HRV) analysis, comparing those reporting emotional and spiritual-related keywords (ESKs) with those not (nESKs).</p><p><strong>Methods: </strong>HCPs from different backgrounds underwent a single 30-minute, individually tailored multimodal IM session (acupuncture, mind-body medicine, and manual/movement modalities). Postintervention narratives from the Measure Yourself Concerns and Well-being (MYCAW) questionnaire were analyzed for clusters of ESKs. HRV parameters were measured (3 minute intervals throughout, to 15 minute postintervention) for change in frequency-domain variable of percentage of high frequency bands (relative power HF, %) and the natural log (Ln) of the HF power, comparing ESKs to nESKs. LF bands (relative power and natural log); root mean square of successive RR interval differences (RMSSD), SD of NN intervals (SDNN), and percentage of successive RR intervals differing by more than 50 ms (pNN50) were also examined.</p><p><strong>Results: </strong>One hundred sixty-two HCPs underwent IM treatment, 136 with high-quality HRV measurements, with 87 (64%) ESKs. Mean relative power HF (%) increased more significantly for ESKs ( p < 0.01), with the Ln HF power increasing only for ESKs, indicating a higher autonomic relaxation status in the ESKs group associated with increased pNN50 ( p = 0.022) and RMSSD/ SDNN ratio ( p = 0.010).</p><p><strong>Conclusions: </strong>HCPs with war-related trauma expressing ESKs showed a greater autonomic relaxation state with the IM intervention than nESKs. Further research needs to examine the relationship between expressing ESKs and HRV parameters among HCPs during wartime.</p><p><strong>Trial registration: </strong>ClinicalTrials.gov identifer: NCT06612749.</p>","PeriodicalId":520402,"journal":{"name":"Biopsychosocial science and medicine","volume":" ","pages":"380-387"},"PeriodicalIF":0.0,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144288109","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Influence of Financial Stress and First-generation College Status on Changes in Inflammation and Depressive Symptoms Across the Transition to College.","authors":"Sarah Rocha, Xochitl Arlene Smola, Ava Trimble, Steve W Cole, Andrew J Fuligni","doi":"10.1097/PSY.0000000000001401","DOIUrl":"10.1097/PSY.0000000000001401","url":null,"abstract":"<p><strong>Objective: </strong>Socioeconomic adversity can hinder successful adjustment to college and may contribute to disparities in health. The present study evaluated whether first-generation college student status and financial stress over college expenses predicted changes in inflammation markers and depressive symptoms across the first year of college.</p><p><strong>Methods: </strong>At the beginning and end of the academic year, a sample of N =198 first-year college students ( Mage =18.1 y) provided dried blood spot samples to estimate concentrations (in log 2 mg/L) of 6 proinflammatory markers: interleukin (IL)-1 receptor agonist, IL-6, IL-8, C-reactive protein, tumor necrosis factor (TNF)-α, and TNF receptor type II. Participants also completed the Center for Epidemiologic Studies Depression scale to measure depressive symptoms at both timepoints. Regression models evaluated associations of financial stress and first-generation college status with baseline and longitudinal change in inflammation and depressive symptoms.</p><p><strong>Results: </strong>We observed that students with greater financial stress and those who were first-generation college students had greater depressive symptoms ( b= 8.07, p =.011; b= 8.39, p <.001) but not inflammation at the start of the academic year. Students with higher financial stress had a greater longitudinal increase in C-reactive protein ( b= 0.72, p =.001) across the academic year, but showed no changes in IL-6, IL-8, IL-1RA, TNF-α, or TNF-RII.</p><p><strong>Conclusions: </strong>First-generation status and college financial stress are related to health challenges during the transition to college. Study findings warrant replication across diverse education environments and point to financial support as a potential target for facilitating healthy adjustment to college.</p>","PeriodicalId":520402,"journal":{"name":"Biopsychosocial science and medicine","volume":" ","pages":"418-426"},"PeriodicalIF":0.0,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144061501","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Depression and Inflammation in Women With Breast Cancer: Risk and Resilience Factors.","authors":"J Richard T Korecki, George M Slavich, Patricia A Ganz, Michael R Irwin, Steve Cole, Catherine M Crespi, Julienne E Bower","doi":"10.1097/PSY.0000000000001398","DOIUrl":"10.1097/PSY.0000000000001398","url":null,"abstract":"<p><strong>Objective: </strong>Diagnosis with breast cancer is a profound stressor associated with increases in depression and inflammation. However, considerable variability in these outcomes is currently unexplained. We examined risk and resilience factors that may influence depressive symptoms and inflammatory markers in recently diagnosed breast cancer patients, including lifetime stressor exposure and psychological and behavioral resources. We focused on modifiable resources-sleep, physical activity, and coping resources-that can be leveraged to enhance women's recovery.</p><p><strong>Methods: </strong>Women with stage 0-IIIA breast cancer ( N = 180) were assessed before radiation, chemotherapy, or endocrine therapy. The Stress and Adversity Inventory (STRAIN) was administered to measure total count and severity of lifetime stressors. Blood samples assessed plasma protein markers of inflammation (TNF-α, IL-6, and CRP) that were combined into a composite score. Self-report questionnaires evaluated depressive symptoms, sleep, physical activity, social support, self-esteem, optimism, and mastery.</p><p><strong>Results: </strong>Total lifetime stressor count (β = 0.30, p < .0001) and severity (β = 0.12, p < .0001) were positively associated with depressive symptoms. Total lifetime stressor count (β = 0.01, p = .04), but not severity (β = 0.001, p = .17), was associated with higher inflammation. Sleep quality, social support, optimism, and mastery buffered the negative effects of lifetime stressor severity on depressive symptoms; social support and optimism also buffered stressor count on depressive symptoms ( p < .04). None of the moderators influenced the stress-inflammation association (all p s > .20).</p><p><strong>Conclusions: </strong>Lifetime stressor exposure is associated with inflammation and depression in breast cancer patients. Interventions enhancing sleep quality, social support, optimism, and mastery may help prevent depression in this vulnerable group.</p>","PeriodicalId":520402,"journal":{"name":"Biopsychosocial science and medicine","volume":" ","pages":"405-417"},"PeriodicalIF":0.0,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144038028","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Psychological Processes Related to Persistent Physical Symptoms in Patients With a Suspected Rare Disease: A Cross-sectional Interview Study.","authors":"Julius Kowalski, Bernd Löwe, Christoph Schramm, Fabian Braun, Franziska Rillig, Natalie Uhlenbusch","doi":"10.1097/PSY.0000000000001403","DOIUrl":"10.1097/PSY.0000000000001403","url":null,"abstract":"<p><strong>Objective: </strong>This cross-sectional interview study aimed to investigate subjective experiences and illness models of patients presenting at a rare disease center. In addition, we strove to identify psychological factors that may be associated with patients' heterogeneous and often unspecific persistent physical symptoms (PPS).</p><p><strong>Methods: </strong>We conducted semi-structured interviews with 27 adult patients [56% female; mean age: M (SD)=44.0 (15.3)] with a suspected rare disease presenting at the Martin Zeitz Center for Rare Diseases in Hamburg, Germany. Numeric rating scales and open-ended questions assessed disease burden, experiences with the health care system, and subjective thoughts and feelings related to PPS, along with psyche-soma interactions and the subjective illness theory. Data were analyzed with qualitative content analysis.</p><p><strong>Results: </strong>All patients reported negative experiences with the health care system, including strained doctor-patient relationships (82%), for instance through stigmatization, and dissatisfaction with care (85%). Patients described several aspects that negatively influenced their PPS, including significant life events before symptom onset (41%), mental stress (44%), and the intense mental focus on symptoms (22%). Participants also described factors improving their PPS, such as psychotherapy (26%) and an optimistic attitude (26%). Some patients had an illness model that integrated psychosocial aspects (19%) while others had a biomedical explanation (26%).</p><p><strong>Conclusions: </strong>Patients with a suspected rare disease describe a variety of challenging experiences with their somatic symptoms and the diagnostic process. Our results support the assumption that psychological aspects may contribute to the heterogeneous and often unspecific somatic symptoms that patients at rare disease centers present with.</p>","PeriodicalId":520402,"journal":{"name":"Biopsychosocial science and medicine","volume":" ","pages":"388-396"},"PeriodicalIF":0.0,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144046059","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Depression and Inflammation Predict Depression Trajectory of Non-Small Cell Lung Cancer Patients.","authors":"Kylie R Park, Peter G Shields, John V Myers, Sarah A Reisinger, Barbara L Andersen","doi":"10.1097/PSY.0000000000001379","DOIUrl":"10.1097/PSY.0000000000001379","url":null,"abstract":"<p><strong>Objective: </strong>Depression and systemic inflammation at diagnosis are associated with poor oncologic outcomes for lung cancer (LC) patients. Research has not explored the interaction of these biomarkers and potential for subsequent psychological morbidity. The aim determines if the co-occurrence of depression and systemic inflammation predicts a worsened trajectory of depressive symptoms from diagnosis through 8 months.</p><p><strong>Methods: </strong>An observational longitudinal cohort design was used (ClinicalTrials.gov Identifier: NCT03199651). Individuals ( N =182) with advanced non-small cell lung cancer were enrolled at diagnosis/pretreatment, had blood drawn, and completed a depression assessment and followed with 8 monthly reassessments. Measures were the Advanced Lung Cancer Inflammation Index (ALI) and self-reported depressive symptoms (Patient Health Questionnaire-9). Using validated cutoffs for biomarkers of inflammation (ALI <24 vs. ALI ≥24) and depression (PHQ <8 vs. PHQ ≥8), the sample was subdivided into 4 cohorts: (1) no/low depression and low inflammation (neither); (2) no/low depression but high inflammation (inflammation); (3) high depression but low inflammation (depression); and (4) high depression and high inflammation (depression+inflammation).</p><p><strong>Results: </strong>Linear mixed models were tested for Group, Time, and Group × Time effects predicting the depression trajectory, adjusting for baseline depression/inflammation, age, partner status, education, smoking history, and cancer treatment. Overall, depressive symptoms did not change across time ( p =0.26), but as predicted, only for Cohort 4 (depression+inflammation) was the interaction significant [ F(24,945) =-0.04, p =0.001], with patients having an elevated depression trajectory.</p><p><strong>Conclusions: </strong>Novel data contribute to the depression pathophysiology literature, showing that co-occurring depression and inflammation can predict depression. Clinically, data suggest a new biobehavioral metric for the identification of depression maintenance in LC patients.</p><p><strong>Trial registration: </strong>ClinicalTrials.gov identifier: NCT03199651.</p>","PeriodicalId":520402,"journal":{"name":"Biopsychosocial science and medicine","volume":" ","pages":"397-404"},"PeriodicalIF":0.0,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144288108","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Circulating Antioxidant Nutrients and Brain Age in Midlife Adults.","authors":"Mason J Lower, Mia K DeCataldo, Thomas E Kraynak, Peter J Gianaros","doi":"10.1097/PSY.0000000000001399","DOIUrl":"10.1097/PSY.0000000000001399","url":null,"abstract":"<p><strong>Objective: </strong>Due to population aging, the increasing prevalence of Alzheimer's disease (AD) and related dementias are major public health concerns. Dietary consumption of antioxidant nutrients, in particular the carotenoid β-carotene, has been associated with less age-related neurocognitive decline. What is unclear, however, is the extent to which antioxidant nutrients may exert neuroprotective effects through their influence on established indicators of age-related changes in brain tissue. This study thus tested associations of circulating β-carotene and other nutrients with a structural neuroimaging indicator of brain age derived from cross-validated machine learning models trained to predict chronological age from brain tissue morphology in independent cohorts.</p><p><strong>Methods: </strong>Midlife adults (N = 132, aged 30.4 to 50.8 y, 59 female at birth) underwent a structural magnetic resonance imaging (MRI) protocol and fasting phlebotomy to assess plasma concentrations of β-carotene, retinol, γ-tocopherol, α-tocopherol, and β-cryptoxanthin.</p><p><strong>Results: </strong>In regression analyses adjusting for chronological age, sex at birth, smoking status, MRI image quality, season of testing, annual income, and education, greater circulating levels of β-carotene were associated with a lower (ie, younger) predicted brain age ( β = -0.23, 95% CI = -0.40 to -0.07, p = .006). Other nutrients were not statistically associated with brain age, and results persisted after additional covariate control for body mass index, cortical volume, and cortical thickness.</p><p><strong>Conclusions: </strong>These cross-sectional findings are consistent with the possibility that dietary intake of β-carotene may be associated with slower biological aging at the level of the brain, as reflected by a neuroimaging indicator of brain age.</p>","PeriodicalId":520402,"journal":{"name":"Biopsychosocial science and medicine","volume":" ","pages":"362-371"},"PeriodicalIF":0.0,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12225730/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144060268","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Posttraumatic Stress Disorder, Obesity, and Epigenetic Aging: A Replication Study in 1828 Veterans.","authors":"Kyle J Bourassa, Melanie E Garrett, Allison E Ashley-Koch, Jean C Beckham, Nathan A Kimbrel","doi":"10.1097/PSY.0000000000001397","DOIUrl":"10.1097/PSY.0000000000001397","url":null,"abstract":"<p><strong>Objective: </strong>Posttraumatic stress disorder (PTSD) is associated with poor health, and prior research suggests that accelerated epigenetic aging could help explain this association. A recent study found that veterans with both PTSD and obesity had greater risk for accelerated epigenetic aging compared with those with either PTSD or obesity individually, or neither condition. The objective of this study was to conduct a replication and extension of this prior work.</p><p><strong>Methods: </strong>This study included models approximating the recent study's analytic approach in a sample of 1828 post-9/11 veterans. Our extension also included additional aging measures (PC-GrimAge and DunedinPACE), a more diverse sample, additional covariates (chronological age, smoking), and use of continuous measures of PTSD, obesity, and accelerated aging.</p><p><strong>Results: </strong>In contrast with the original report, we did not find evidence that obesity moderated the association of PTSD and aging, indicating that veterans with both conditions had greater risk for accelerated aging. Although several significant interactions were observed, they were in the opposite direction of the original study findings (ie, PTSD was more strongly associated with aging scores among veterans with less body mass). Our results instead demonstrated that PTSD was associated with accelerated aging across all continuously measured aging scores (0.08 ≤all βs ≤0.10), and that obesity was associated with faster DunedinPACE aging scores [β=0.36, 95% CI (0.28, 0.44)].</p><p><strong>Conclusions: </strong>Our findings provide additional evidence that PTSD and obesity may be useful targets for interventions aiming to slow aging and improve health.</p>","PeriodicalId":520402,"journal":{"name":"Biopsychosocial science and medicine","volume":" ","pages":"355-361"},"PeriodicalIF":0.0,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144311173","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Personality Traits and the Risk of Osteoporosis in 3 Longitudinal Samples.","authors":"Yannick Stephan, Angelina R Sutin, Brice Canada, Antonio Terracciano","doi":"10.1097/PSY.0000000000001404","DOIUrl":"10.1097/PSY.0000000000001404","url":null,"abstract":"<p><strong>Objective: </strong>Osteoporosis is a prevalent age-related condition with significant individual and economic costs. Identifying factors implicated in the risk of osteoporosis is thus critical to designing effective preventive actions and interventions. This study examined the cross-sectional and prospective associations between the 5 major personality traits and the risk of osteoporosis.</p><p><strong>Methods: </strong>Participants were older adults aged 50 to 104 years ( N >20,000) from the Health and Retirement Study, the English Longitudinal Study of Ageing, and the National Health and Aging Trends Study. Baseline measures of personality traits, demographic, clinical, and behavioral factors were obtained in the 3 samples. Data on osteoporosis diagnosis were reported at baseline and up to 10 years later.</p><p><strong>Results: </strong>Random effect meta-analyses indicated that higher neuroticism was related to a higher risk of concurrent [odds ratios (OR)= 1.16, 95% CI: 1.11-1.21] and incident [hazard ratios (HR)= 1.18, 95% CI: 1.13-1.24] osteoporosis, whereas higher extraversion and higher conscientiousness were associated with a lower risk of concurrent (OR: 0.91, 95% CI: 0.85-0.97 and OR: 0.93, 95% CI: 0.89-0.98, respectively) and incident (HR: 0.92, 95% CI: 0.85-1.00 and HR: 0.91, 95% CI: 0.84-0.98, respectively) osteoporosis. Openness and agreeableness were unrelated to osteoporosis. Chronic conditions, BMI, physical activity, and smoking partly explained these associations. There was little replicable evidence for moderation by age and sex.</p><p><strong>Conclusions: </strong>Consistent with other chronic conditions, this multicohort study provides novel evidence that higher neuroticism is a vulnerability factor for osteoporosis, whereas extraversion and conscientiousness are protective.</p>","PeriodicalId":520402,"journal":{"name":"Biopsychosocial science and medicine","volume":" ","pages":"372-379"},"PeriodicalIF":0.0,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144236714","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Acute Active, but not Passive, Psychological Stress Increases non-classical Monocyte Proportions.","authors":"Victoria G Linsley, Nicolette C Bishop, Matthew J Roberts, Nicola J Paine","doi":"10.1097/PSY.0000000000001416","DOIUrl":"https://doi.org/10.1097/PSY.0000000000001416","url":null,"abstract":"<p><strong>Objective: </strong>Psychological stress exposure is a modifiable risk factor for cardiovascular disease (CVD), possibly through promoting a heightened inflammatory milieu. Under psychological stress, changes in monocyte subsets from classical (CM) to intermediate (IM) and non-classical (NCM) could indicate a more pro-inflammatory environment. We investigated the impact of acute psychological stress (active and passive) on monocyte subsets and leukocyte count ratios.</p><p><strong>Methods: </strong>Twenty-four participants completed a 20-min baseline period, followed by a passive (International Affective Picture System: IAPS) and active stress task (socially evaluative Paced Auditory Serial Addition Test: PASAT) with 90-min recovery after each task. Blood samples were collected to determine changes in: CM, IM and NCM count/proportions, systemic inflammation response index (SIRI) and neutrophil:lymphocyte ratio (NLR).</p><p><strong>Results: </strong>CM proportions decreased (89.4% to 87.0%; P=0.007) and NCM proportions increased (6.8% to 2.1%; P=0.035) from baseline to immediately post-PASAT. There were no differences in monocyte subsets from baseline to post-IAPS (CM% P>0.99; IM% P=>0.99; NCM% P>0.99). NLR and SIRI did not differ from baseline in response to either the PASAT or IAPS (P>0.05).</p><p><strong>Conclusion: </strong>Acute active, but not passive, psychological stress promoted a transition in monocyte subsets towards a more pro-inflammatory environment, which may be an important advancement in markers used to assess the inflammatory response to acute psychological stress.</p>","PeriodicalId":520402,"journal":{"name":"Biopsychosocial science and medicine","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-06-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144562577","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}