BMC global and public health最新文献

{"title":"Author Correction: Cautiously optimistic: paediatric critical care nurses' perspectives on data-driven algorithms in low-resource settings-a human-centred design study in Malawi.","authors":"Margot Rakers, Daniel Mwale, Lieke de Mare, Lezzie Chirambo, Bart Bierling, Alice Likumbo, Josephine Langton, Niels Chavannes, Hendrikus van Os, Job Calis, Kiran Dellimore, María Villalobos-Quesada","doi":"10.1186/s44263-025-00146-w","DOIUrl":"10.1186/s44263-025-00146-w","url":null,"abstract":"","PeriodicalId":519903,"journal":{"name":"BMC global and public health","volume":"3 1","pages":"22"},"PeriodicalIF":0.0,"publicationDate":"2025-03-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11924623/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143672223","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association between social capital and mortality among community-dwelling older adults in Myanmar 2018-2022: a prospective cohort study.","authors":"Yuka Ohaku, Yuki Shirakura, Yuiko Nagamine, Yuri Sasaki, Daisuke Takagi, Ikuma Nozaki, Than Win Nyunt, Reiko Saito, Yugo Shobugawa","doi":"10.1186/s44263-025-00137-x","DOIUrl":"10.1186/s44263-025-00137-x","url":null,"abstract":"<p><strong>Background: </strong>Healthy aging is crucial in Asia given its rapidly aging society. Social capital, which refers to the resources derived from social networks, norms, and trust that facilitate cooperation and collective action within a community or society, has demonstrated health benefits for older adults. However, its impact varies by country. Most research focuses on high-income countries, with little attention on low- and middle-income countries.</p><p><strong>Methods: </strong>This prospective cohort study examined the effects of social capital on all-cause mortality among older adults in Myanmar from 2018 to 2022, using structured questionnaires based on the Japan Gerontological Evaluation Study. Multistage random sampling and face-to-face interviews were conducted with community-dwelling older adults aged 60 and above in Yangon and Bago in 2018. Subsequently, three waves of follow-up telephone surveys were conducted in 2020, 2021, and 2022. The questionnaires evaluated three components of social capital: civic participation, social cohesion, and social support, alongside baseline demographic information. Their impact on all-cause mortality was assessed using the Cox proportional hazards model with multiple imputations, adjusting for potential confounders including age, gender, body mass index, self-rated health, socioeconomic status, lifestyle, illness, and residential area.</p><p><strong>Results: </strong>A total of 1200 individuals were followed for an average of 2.6 years (3123 person-years), with 143 all-cause deaths observed among 1031 participants. Bivariate analyses showed that participants who died were more likely to be older, underweight, have shorter daily walking times, live in Bago, and have less social support. Higher social support was significantly associated with lower mortality after adjusting for all covariates (HR = 0.80, 95% CI 0.69-0.94). Specifically, instrumental support, defined as the exchange of practical assistance, such as receiving or providing care during illness, was found to be protectively associated with mortality. When stratified by residential area, significant associations were found only in Bago, a rural area. Among older adults in Myanmar, instrumental support was a more prominent protector against all-cause mortality than emotional support, especially in rural areas.</p><p><strong>Conclusions: </strong>Our findings indicate that social support networks play an important role in the survival of older adults in Myanmar, even under unstable social conditions.</p>","PeriodicalId":519903,"journal":{"name":"BMC global and public health","volume":"3 1","pages":"21"},"PeriodicalIF":0.0,"publicationDate":"2025-03-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11912608/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143653028","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Whole genome sequencing and phylogenetic analysis of dengue virus in Central Nepal from 2022 to 2023.","authors":"Margaret Chi, Nishan Katuwal, Aastha Shrestha, Surendra Kumar Madhup, Dipesh Tamrakar, Rajeev Shrestha","doi":"10.1186/s44263-025-00135-z","DOIUrl":"10.1186/s44263-025-00135-z","url":null,"abstract":"<p><strong>Background: </strong>In Nepal, dengue is an emerging disease of growing concern as outbreaks are increasing in both size and geographic reach and beginning to affect areas previously thought dengue-free. Dengue genomic surveillance has previously been limited within Nepal; however, with the increase in accessibility to sequencing technologies since the COVID-19 pandemic, it has recently become more feasible.</p><p><strong>Methods: </strong>This hospital-based retrospective study utilized banked samples from the 2022 and 2023 dengue seasons from Dhulikhel Hospital/Kathmandu University Hospital in Central Nepal. Next-generation sequencing was performed to obtain whole genome sequences of dengue virus which were analyzed phylogenetically using a maximum likelihood GTR + G model. Mutations were evaluated across viral particle region using the GISAID DengueServer.</p><p><strong>Results: </strong>We obtained 41 full-length sequences of DENV from 80 PCR-positive samples, including 24 sequences (58.5%) from 2022 and 17 sequences (41.5%) from 2023. We identified a shift in the majority serotype of our samples from DENV1 in 2022 to DENV3 in 2023, though 3 out of the 4 serotypes were identified in both years. Phylogenetic analysis revealed clusters within genotype III of DENV1 and genotype III of DENV3 closely related to strains from an outbreak of DENV in northern India in 2018-2019. DENV2 sequences fell into the cosmopolitan genotype IV-A1 and IV-B2 clades and were related to sequences from South and Southeast Asia and the USA, pointing to the global nature of dengue transmission. NS3 showed the highest frequency of mutation, whereas NS2B, NS4, NS5, and E were the most conserved. The most common mutations found were substitutions L17M and T20I in the 2 K peptide. A high number of mutations were observed in DENV3, followed by DENV2, with some mutations being unique to specific serotypes and others matching previously reported strains.</p><p><strong>Conclusions: </strong>We identified possible clade shifts in the DENV1 and 2 populations and a rising prevalence of DENV3. Our study showed a high level of serotype diversity of DENV circulating in Central Nepal. Furthermore, our results indicate that DENV populations in Nepal are related to a geographically diverse set of sequences but are most strongly influenced by Indian strains of DENV.</p>","PeriodicalId":519903,"journal":{"name":"BMC global and public health","volume":"3 1","pages":"18"},"PeriodicalIF":0.0,"publicationDate":"2025-03-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11884168/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143569359","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Perspectives on multisectoral accountability framework to end tuberculosis in the Eastern Europe and Central Asia region: a mixed-methods study.","authors":"Yuliya Chorna, Ievgeniia-Galyna Lukash, Yuliia Kalancha, Lesia Tonkonoh, Marifat Abdullaeva, Malik Adenov, Mariia Chuprynska, Sayohat Hasanova, Oxana Ibragimova, Panagul Jazybekova, Nataliia Kamenska, Olya Klymenko, Iryna Koroieva, Lyubov Kravets, Nataliia Kryshtafovych, Lucia Pirtina, Alena Skrahina, Yana Terleeva, Valentina Vilc, Hanna Zakrevska, Dmitry Zhurkin, James Malar, Amrita Daftary","doi":"10.1186/s44263-025-00136-y","DOIUrl":"10.1186/s44263-025-00136-y","url":null,"abstract":"<p><strong>Background: </strong>Sectors beyond health are essential to combatting a social disease such as tuberculosis (TB). The engagement of the community and civil society sector in Eastern Europe and Central Asia was assessed as part of a broader baseline assessment of multisectoral engagement in national TB responses.</p><p><strong>Methods: </strong>This was a mixed-methods community-based study. Surveys, interviews, and focus groups were conducted online with TB-engaged community and civil society representatives in Belarus, Kazakhstan, Moldova, Tajikistan, and Ukraine from January to June 2021. Quantitative data, analyzed using descriptive statistics, were triangulated with thematic qualitative analysis. A multisectoral accountability framework and community, rights, and gender framework for TB were used to triangulate the findings and inform data interpretations.</p><p><strong>Results: </strong>Participants (n = 160) included leads, service providers from 74 organizations, and TB survivors. Of 53 survey respondents, most (n = 41, 77·4%) indicated strong/complete agreement to participating in TB service delivery and gender, stigma, and/or legal assessments (n = 27, 50·9%) and research processes (n = 30, 56·6%). However, few indicated inclusion in operational planning and budgeting (n = 13, 24·5%), or political and program impact of community-led monitoring (n = 16, 30·2%), and almost none (n = 2, 3.8%) confirmed dedicated budgets for their TB-related work. Inquiry into the dimensions and criteria for multisectoral actions and accountability revealed their key, yet limited, role in attending to social determinants, with wider engagement hindered by precarious funding. Several organizations balanced building partnerships with other sectors engaged in the TB response against advocacy activities. Inherent obligations toward TB-affected communities were at times overshadowed by obligations to donors and state actors. Coordinating bodies for donor funds, which were multisectoral by design, presented an opportunity to bolster accountability actions within the TB response.</p><p><strong>Conclusions: </strong>Multisectoral engagement and accountability for TB are a laudable and necessary goal to end TB. Sustainable mechanisms to support the meaningful involvement of TB-affected communities and civil society are needed, particularly in the context of donor transitions.</p>","PeriodicalId":519903,"journal":{"name":"BMC global and public health","volume":"3 1","pages":"20"},"PeriodicalIF":0.0,"publicationDate":"2025-03-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11884184/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143569358","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Innovative vaccine research through the lens of implementation science: fulfilling the strategic goals of the Immunization Agenda 2030.","authors":"Kangning Sheng, Kan Chen, Yingqi Chen, Linchen Chu, Chenlu Fan, Chuanxi Fu","doi":"10.1186/s44263-025-00132-2","DOIUrl":"10.1186/s44263-025-00132-2","url":null,"abstract":"","PeriodicalId":519903,"journal":{"name":"BMC global and public health","volume":"3 1","pages":"19"},"PeriodicalIF":0.0,"publicationDate":"2025-03-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11874764/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143538249","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Children and young people at the intersection of chronic illness and migration: a scoping review.","authors":"Brenda Agyeiwaa Poku, Lucy Hunt, Alison Pilnick, Karl Michael Atkin, Catrin Evans, Emily Pulsford, Susan Kirk","doi":"10.1186/s44263-025-00131-3","DOIUrl":"10.1186/s44263-025-00131-3","url":null,"abstract":"<p><strong>Background: </strong>Chronic illnesses (CIs) are increasingly prevalent among children/young people (CYP) globally. For migrant CYP with CIs, achieving a stable life in a new country can be particularly challenging due to additional barriers such as cultural and language differences, unsafe living conditions, and discrimination. While migration can sometimes improve healthcare access by introducing new models of care and ways of understanding health, these advantages are often outweighed by obstacles that hinder access to essential services. This review aimed to map the global evidence on post-migration experiences and outcomes of CYP with CIs and to identify priorities for research, policy, and practice to improve their care.</p><p><strong>Methods: </strong>A scoping review was conducted following JBI guidelines. We searched seven online databases, including MEDLINE, Embase, PsycINFO, Cochrane Library, CINAHL, Social Science Collection, and Web of Science, up to February 2024. Data were synthesised using a socio-ecological model, and four young migrants living with sickle cell disease in the UK contributed to the review through a Patient and Public Involvement Advisory Group.</p><p><strong>Results: </strong>Of the 58 included papers, most focused on migration to high-income countries, particularly the USA, and used institutional records or case studies. Few studies provided detailed information about migration status or reason for migration, often using proxies like parental country of birth or language spoken. The socio-ecological model revealed disparities in health status, treatment access, and health outcomes for migrant CYP with CIs. Key challenges were language, communication, costs, bureaucracy, family dynamics, coordination issues, resource constraints, and socio-political influences. Significant gaps included a lack of intersectional analyses (e.g. accounting for 'race' and citizenship) and limited qualitative research capturing the lived experiences of migrant CYP with CIs.</p><p><strong>Conclusions: </strong>Migrant CYP with CIs face significant health disparities shaped by individual, social, and systemic factors. Addressing these challenges requires intersectional and qualitative research, alongside collaboration with policymakers, practitioners, and communities, to inform more equitable healthcare policies and practices.</p>","PeriodicalId":519903,"journal":{"name":"BMC global and public health","volume":"3 1","pages":"14"},"PeriodicalIF":0.0,"publicationDate":"2025-03-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11874703/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143538212","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Enriching tuberculosis research by measuring poverty better: a perspective.","authors":"Chelsie Cintron, Madolyn Rose Dauphinais, Xinyi Du, Alexa Tabackman, Andrew Lenart, Ashley Laliberte, Jakob Dirksen, Pranay Sinha","doi":"10.1186/s44263-025-00127-z","DOIUrl":"10.1186/s44263-025-00127-z","url":null,"abstract":"<p><p>The relationship between poverty and tuberculosis (TB) is well-documented, as socio-economic deprivation constitutes a risk factor that drives TB transmission and progression while hindering treatment adherence. Despite the importance of controlling for socio-economic status (SES) in TB research, no universally accepted tool exists to measure multidimensional poverty's impact on TB-affected households. This article provides an overview of existing SES assessment tools, including income-based measures, wealth indices like the Demographic and Health Survey (DHS) and the International Wealth Index (IWI), and multidimensional indices, such as the global Multidimensional Poverty Index (MPI). Each method's strengths and limitations are considered, particularly in light of the complex deprivations relevant to TB. Recognizing the distinct SES determinants of TB, we emphasize the need for multidimensional, standardized SES measures that are contextually relevant and feasible for TB epidemiology, programmatic evaluations, and translational research. By advancing poverty metrics in TB studies, the global community can better address socio-economic drivers of TB and prioritize pro-poor interventions, fostering equitable health outcomes.</p>","PeriodicalId":519903,"journal":{"name":"BMC global and public health","volume":"3 1","pages":"17"},"PeriodicalIF":0.0,"publicationDate":"2025-02-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11843788/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143470441","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Envisioning sustainable oral health through effective advocacy.","authors":"Manu Raj Mathur, Ankita Shashikant Bhosale, Stephen N Abel, Julian Fisher, Stefan Listl, Alonso Carrasco-Labra, Olivia Urquhart, Michael Glick","doi":"10.1186/s44263-025-00133-1","DOIUrl":"10.1186/s44263-025-00133-1","url":null,"abstract":"<p><p>In recent years, global commitments have endeavored to reduce the burden of oral diseases. To maintain this momentum, effective advocacy for sustainable oral health is needed to raise public awareness, garner support, and guide policy makers. However, there has been limited use of evidence-based frameworks and approaches to design and measure the impact of oral health advocacy efforts. The 2nd Global Oral Health Forum (GOHF II) was hosted in April 2024 over a 2-day period to reflect on and discuss effective advocacy approaches and strategies for sustainable oral health. Four thematic sessions were organized around advocacy including health policies, health economics, patients, and planetary health. Each session featured eminent transdisciplinary speakers followed by group discussions centered around ideas, experiences, and perspectives from forum participants. The outcome of the forum was a compilation of ten actionable recommendations for moving forward with effective advocacy in oral health. These recommendations are envisioned to help build and strengthen coalitions of like-minded stakeholders in and outside the oral health community to advocate for policies that support sustainable oral health and equitable access to oral health care.</p>","PeriodicalId":519903,"journal":{"name":"BMC global and public health","volume":"3 1","pages":"15"},"PeriodicalIF":0.0,"publicationDate":"2025-02-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11841293/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143461504","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Building health research capacity in Africa: the Einstein-Rwanda research and capacity building program.","authors":"Gad Murenzi, Gallican Kubwimana, Fidel Rubagumya, Pacifique Mugenzi, Alex Buteera, Emmanuel Rudakemwa, Jonathan Ross, Tiffany Hebert, Adebola Adedimeji, Sabin Nsanzimana, Marcel Yotebieng, Joel Palefsky, Leon Mutesa, Philip E Castle, Kathryn Anastos","doi":"10.1186/s44263-025-00134-0","DOIUrl":"10.1186/s44263-025-00134-0","url":null,"abstract":"<p><p>The growing demand for healthcare services and the burden of diseases such as cancer in sub-Saharan Africa (SSA) requires locally-led and setting-relevant evidence that should be driven by local investigators. However, there is a huge gap in the health research capacity to generate such evidence in most of SSA, particularly in Rwanda. With a changing focus and the willingness of investigators and funders from high-income countries (HICs) to support investigators and research from SSA, it is important to build strong, successful, and sustained partnerships. In this perspective, we describe the Einstein-Rwanda Research and Capacity Building Program (ER-RCBP), which represents almost two decades of a fruitful and sustained partnership that has contributed to the development of research physical and human resources in Rwanda. We have established a broad range of health research infrastructure that involves human resources, including training three pathologists, leadership and administrative personnel and structures, clinical research operations, laboratory capacity, and data collection and management systems, and are implementing a long-term plan to transfer most of the leadership to local investigators and the local lead institution. Our experience demonstrates that collaborations between high- and low-income countries can be leveraged to strengthen research capacity in SSA but that such efforts require putting in place structures and systems to ensure success. Building strong partnerships and collaborations, good leadership, empowering local teams, and having buy-in from national governments are key to achieving sustainable research capacity in SSA.</p>","PeriodicalId":519903,"journal":{"name":"BMC global and public health","volume":"3 1","pages":"16"},"PeriodicalIF":0.0,"publicationDate":"2025-02-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11841342/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143461502","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Eco-bio-communitarianism: reimagining bioethics for sustainable health.","authors":"Nchangwi Syntia Munung, Godfrey B Tangwa","doi":"10.1186/s44263-025-00129-x","DOIUrl":"10.1186/s44263-025-00129-x","url":null,"abstract":"","PeriodicalId":519903,"journal":{"name":"BMC global and public health","volume":"3 1","pages":"13"},"PeriodicalIF":0.0,"publicationDate":"2025-02-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11817090/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143401171","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}