Medecine sciences : M/S最新文献

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[Does metabolism protect our immune system?] 新陈代谢能保护我们的免疫系统吗?]
IF 0.7
Medecine sciences : M/S Pub Date : 2022-06-01 Epub Date: 2022-06-29 DOI: 10.1051/medsci/2022075
Laurent Yvan-Charvet, Béatrice Bailly-Maitre
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引用次数: 0
[The human genome - again?] [又是人类基因组?]
IF 0.7
Medecine sciences : M/S Pub Date : 2022-06-01 Epub Date: 2022-06-29 DOI: 10.1051/medsci/2022086
Bertrand Jordan
{"title":"[The human genome - again?]","authors":"Bertrand Jordan","doi":"10.1051/medsci/2022086","DOIUrl":"https://doi.org/10.1051/medsci/2022086","url":null,"abstract":"","PeriodicalId":519512,"journal":{"name":"Medecine sciences : M/S","volume":"38 6-7","pages":"509-510"},"PeriodicalIF":0.7,"publicationDate":"2022-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40408947","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Autophagy facilitates mitochondrial network rebuilding after heat stress in the nematode C. elegans]. [线虫热应激后自噬促进线粒体网络重建]。
IF 0.7
Medecine sciences : M/S Pub Date : 2022-06-01 Epub Date: 2022-06-29 DOI: 10.1051/medsci/2022074
Romane Leboutet, Renaud Legouis
{"title":"[Autophagy facilitates mitochondrial network rebuilding after heat stress in the nematode C. elegans].","authors":"Romane Leboutet, Renaud Legouis","doi":"10.1051/medsci/2022074","DOIUrl":"https://doi.org/10.1051/medsci/2022074","url":null,"abstract":"","PeriodicalId":519512,"journal":{"name":"Medecine sciences : M/S","volume":"38 6-7","pages":"517-519"},"PeriodicalIF":0.7,"publicationDate":"2022-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40408949","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[A subpopulation of hepatic macrophages involved in metabolism regulation]. [肝巨噬细胞亚群参与代谢调节]。
IF 0.7
Medecine sciences : M/S Pub Date : 2022-06-01 Epub Date: 2022-06-29 DOI: 10.1051/medsci/2022070
Camille Blériot, Florent Ginhoux
{"title":"[A subpopulation of hepatic macrophages involved in metabolism regulation].","authors":"Camille Blériot, Florent Ginhoux","doi":"10.1051/medsci/2022070","DOIUrl":"https://doi.org/10.1051/medsci/2022070","url":null,"abstract":"","PeriodicalId":519512,"journal":{"name":"Medecine sciences : M/S","volume":"38 6-7","pages":"532-536"},"PeriodicalIF":0.7,"publicationDate":"2022-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40408641","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
[Maternal odor helps infants to categorize face-like objects]. [母亲的气味有助于婴儿对类似人脸的物体进行分类]。
IF 0.7
Medecine sciences : M/S Pub Date : 2022-06-01 Epub Date: 2022-06-29 DOI: 10.1051/medsci/2022067
Arnaud Leleu, Diane Rekow
{"title":"[Maternal odor helps infants to categorize face-like objects].","authors":"Arnaud Leleu, Diane Rekow","doi":"10.1051/medsci/2022067","DOIUrl":"https://doi.org/10.1051/medsci/2022067","url":null,"abstract":"","PeriodicalId":519512,"journal":{"name":"Medecine sciences : M/S","volume":"38 6-7","pages":"541-544"},"PeriodicalIF":0.7,"publicationDate":"2022-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40408639","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
[SARS-CoV-2 has no origin]. [SARS-CoV-2没有起源]。
IF 0.7
Medecine sciences : M/S Pub Date : 2022-06-01 Epub Date: 2022-06-29 DOI: 10.1051/medsci/2022079
Roger Frutos, Laurent Gavotte, Christian A Devaux
{"title":"[SARS-CoV-2 has no origin].","authors":"Roger Frutos,&nbsp;Laurent Gavotte,&nbsp;Christian A Devaux","doi":"10.1051/medsci/2022079","DOIUrl":"https://doi.org/10.1051/medsci/2022079","url":null,"abstract":"<p><p>Since the beginning of the COVID-19 pandemic, the question of the origin of this virus has been the subject of a vivid controversy. It is the question of the \"origin\" itself which is biased. Darwin showed that there is no determined origin to any animal or plant species, simply an evolutionary and selective process. The same is true for viruses, there is no origin, but an evolutionary process. Viruses circulate from host to host, animals or humans. Pandemic viruses are already circulating in humans and evolving before the onset of disease. This evolutionary process then continues and gives rise to successive variants. The solution is not to target the disease or the putative causative agent but rather to address the process of disease emergence.</p>","PeriodicalId":519512,"journal":{"name":"Medecine sciences : M/S","volume":"38 6-7","pages":"600-607"},"PeriodicalIF":0.7,"publicationDate":"2022-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40409416","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Food emulsifiers and intestinal microbiota: beware of your muffin!] 食物乳化剂和肠道微生物群:小心你的松饼!]
IF 0.7
Medecine sciences : M/S Pub Date : 2022-06-01 Epub Date: 2022-06-29 DOI: 10.1051/medsci/2022068
Erica Bonazzi, Clara Delaroque, Benoit Chassaing
{"title":"[Food emulsifiers and intestinal microbiota: beware of your muffin!]","authors":"Erica Bonazzi,&nbsp;Clara Delaroque,&nbsp;Benoit Chassaing","doi":"10.1051/medsci/2022068","DOIUrl":"https://doi.org/10.1051/medsci/2022068","url":null,"abstract":"","PeriodicalId":519512,"journal":{"name":"Medecine sciences : M/S","volume":"38 6-7","pages":"539-541"},"PeriodicalIF":0.7,"publicationDate":"2022-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40408637","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Resistance to BRAF inhibitors: A lesson from clinical observations]. [对BRAF抑制剂的耐药性:来自临床观察的教训]。
IF 0.7
Medecine sciences : M/S Pub Date : 2022-06-01 Epub Date: 2022-06-29 DOI: 10.1051/medsci/2022083
Cylia Dahmani, Eulalie Corre, Sarah Dandou, Alain Mangé, Ovidiu Radulescu, Peter J Coopman, Pierre Cuq, Romain M Larive
{"title":"[Resistance to BRAF inhibitors: A lesson from clinical observations].","authors":"Cylia Dahmani,&nbsp;Eulalie Corre,&nbsp;Sarah Dandou,&nbsp;Alain Mangé,&nbsp;Ovidiu Radulescu,&nbsp;Peter J Coopman,&nbsp;Pierre Cuq,&nbsp;Romain M Larive","doi":"10.1051/medsci/2022083","DOIUrl":"https://doi.org/10.1051/medsci/2022083","url":null,"abstract":"<p><p>The MAPK/ERK pathway is an essential intracellular signaling pathway. Its deregulation is involved in tumor transformation and progression. The discovery of activating mutations of BRAF in various cancers has opened new therapeutic avenues with BRAF protein kinase inhibitors. Depending on the type of cancers, these inhibitors have shown either insufficient efficacy due to primary resistance of tumor cells or transient efficacy due to the development of acquired resistance. In this review, we revisit the discoveries that led to the development of BRAF inhibitors and detail the molecular and cellular mechanisms of resistance in cancers treated with these inhibitors. Understanding these mechanisms is crucial for developing more efficient therapeutic strategies.</p>","PeriodicalId":519512,"journal":{"name":"Medecine sciences : M/S","volume":"38 6-7","pages":"570-578"},"PeriodicalIF":0.7,"publicationDate":"2022-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40408642","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[How the brain gets rid of supernumerary synapses during development]. [大脑在发育过程中如何去除多余的突触]。
IF 0.7
Medecine sciences : M/S Pub Date : 2022-06-01 Epub Date: 2022-06-29 DOI: 10.1051/medsci/2022076
Sabine Lévi, Christophe Bernard
{"title":"[How the brain gets rid of supernumerary synapses during development].","authors":"Sabine Lévi,&nbsp;Christophe Bernard","doi":"10.1051/medsci/2022076","DOIUrl":"https://doi.org/10.1051/medsci/2022076","url":null,"abstract":"","PeriodicalId":519512,"journal":{"name":"Medecine sciences : M/S","volume":"38 6-7","pages":"511-513"},"PeriodicalIF":0.7,"publicationDate":"2022-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40408946","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Ethical questioning on the posture of the physician-scientist]. [对医师兼科学家姿态的伦理质疑]。
IF 0.7
Medecine sciences : M/S Pub Date : 2022-03-01 Epub Date: 2022-03-25 DOI: 10.1051/medsci/2022030
Virgile Clergue-Duval
{"title":"[Ethical questioning on the posture of the physician-scientist].","authors":"Virgile Clergue-Duval","doi":"10.1051/medsci/2022030","DOIUrl":"https://doi.org/10.1051/medsci/2022030","url":null,"abstract":"Questionnement éthique sur la posture du médecin-chercheur.\u0000 À l’occasion d’un projet de recherche clinique réalisé dans le cadre de mon travail de thèse de science et de ma pratique de recherche clinique en médecine, j’ai été confronté au refus d’un patient de participer à un protocole. Ce refus n’était pas le premier auquel j’étais confronté, mais il m’a surpris et m’a fait m’interroger sur ma pratique en tant que chercheur et sur ma manière d’introduire la problématique de la recherche dans mon exercice de médecin addictologue.","PeriodicalId":519512,"journal":{"name":"Medecine sciences : M/S","volume":"38 3","pages":"309-311"},"PeriodicalIF":0.7,"publicationDate":"2022-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40324841","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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