Journal of General and Family Medicine最新文献

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Addressing healthcare needs in an inaugural family medicine clinic in a core city in Japan: Mixed-methods research 解决日本核心城市首个家庭医学诊所的医疗保健需求:混合方法研究
IF 1.8
Journal of General and Family Medicine Pub Date : 2025-03-21 DOI: 10.1002/jgf2.777
Junki Mizumoto MD, PhD, Maki Nishimura MD, MSc, Naoko Ishikawa MD, MSc, PhD, Kana Hisatake MD, Eri Satake, Shizuka Yamamoto, Shota Tsuno
{"title":"Addressing healthcare needs in an inaugural family medicine clinic in a core city in Japan: Mixed-methods research","authors":"Junki Mizumoto MD, PhD,&nbsp;Maki Nishimura MD, MSc,&nbsp;Naoko Ishikawa MD, MSc, PhD,&nbsp;Kana Hisatake MD,&nbsp;Eri Satake,&nbsp;Shizuka Yamamoto,&nbsp;Shota Tsuno","doi":"10.1002/jgf2.777","DOIUrl":"https://doi.org/10.1002/jgf2.777","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>There exists little research elucidating the benefits of family medicine clinics for community with ample specialist healthcare resources.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>We conducted mixed-methods research. Within the inaugural family medicine clinic, the following data was collected during the initial 2 months: (i) newly identified healthcare needs among scheduled outpatients; (ii) management of outpatients with complex health and social needs; and (iii) provision of home-visit care. Newly detected health care needs were summarized qualitatively using a summative content analysis. Patients' complexity was quantitatively scored using the Japanese version of the Patient Centred Assessment Method.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Physicians identified 156 new needs and 13 complex cases. The complexity of patients receiving home-visit care was high.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>This study demonstrates that an inaugural family medicine clinic adeptly addressed a diverse spectrum of patients' healthcare needs.</p>\u0000 </section>\u0000 </div>","PeriodicalId":51861,"journal":{"name":"Journal of General and Family Medicine","volume":"26 3","pages":"269-272"},"PeriodicalIF":1.8,"publicationDate":"2025-03-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/jgf2.777","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143871678","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Shining stars in the sky on the gastric mucosa 天上的星星在胃粘膜上闪闪发光
IF 1.8
Journal of General and Family Medicine Pub Date : 2025-03-12 DOI: 10.1002/jgf2.70011
Kosuke Minaga MD, PhD, Hajime Honjo MD, PhD, Tomohiro Watanabe MD, PhD, Masatoshi Kudo MD, PhD
{"title":"Shining stars in the sky on the gastric mucosa","authors":"Kosuke Minaga MD, PhD,&nbsp;Hajime Honjo MD, PhD,&nbsp;Tomohiro Watanabe MD, PhD,&nbsp;Masatoshi Kudo MD, PhD","doi":"10.1002/jgf2.70011","DOIUrl":"https://doi.org/10.1002/jgf2.70011","url":null,"abstract":"<p>We report a rare case of an elderly Japanese man diagnosed with sporadic gastric Burkitt lymphoma. Esophagogastroduodenoscopy showed nodular and ulcerated lesions in the lesser curvature of the stomach. Pathological analysis of showed that the gastric lesions are characterized by a diffuse and dense accumulation of dark atypical lymphocytes (night) and a scattered distribution of bright foamy macrophages (stars) that give the classic “starry sky” appearance.\u0000 <figure>\u0000 <div><picture>\u0000 <source></source></picture><p></p>\u0000 </div>\u0000 </figure></p>","PeriodicalId":51861,"journal":{"name":"Journal of General and Family Medicine","volume":"26 4","pages":"368-369"},"PeriodicalIF":1.8,"publicationDate":"2025-03-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/jgf2.70011","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144582320","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
“The future”: Interpretative phenomenological analysis of general practitioners' experiences of co-employed clinical psychologists “未来”:全科医生与临床心理学家合作经验的解释性现象学分析
IF 1.8
Journal of General and Family Medicine Pub Date : 2025-02-24 DOI: 10.1002/jgf2.774
Katie Monnickendam D.Clin.Psy, Peter Keohane D.Clin.Psy, Rebecca Magill D.Clin.Psy
{"title":"“The future”: Interpretative phenomenological analysis of general practitioners' experiences of co-employed clinical psychologists","authors":"Katie Monnickendam D.Clin.Psy,&nbsp;Peter Keohane D.Clin.Psy,&nbsp;Rebecca Magill D.Clin.Psy","doi":"10.1002/jgf2.774","DOIUrl":"https://doi.org/10.1002/jgf2.774","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>General practice is overwhelmed and understaffed. New models and modalities must be considered from the front door of healthcare. Like general practitioners (GPs), clinical psychologists are qualified to work across the age range and transdiagnostically.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Aim</h3>\u0000 \u0000 <p>To explore GPs' understanding of the role of a clinical psychologist and to examine what is helpful and unhelpful for GPs about working alongside a clinical psychologist within general practice.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Design and Setting</h3>\u0000 \u0000 <p>This research took place within a primary care general practice in the United Kingdom.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Method</h3>\u0000 \u0000 <p>Seven qualified GPs were recruited as participants using a purposive sampling method. Interpretative phenomenological analysis was used to analyze participant's experiences of working alongside clinical psychologists.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Three superordinate themes and 12 subordinate themes were identified. First, GP clinical psychologists support patients directly by providing preventative care, reducing stigma, and offering a different perspective. Second, they support GP well-being and contribute to emotional and behavioral changes in staff. Third, they help to alleviate pressures on wider systems, ease navigation of external services, challenge dominant systems within healthcare, and support community interventions.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>GP clinical psychologists impact general practice in multiple ways: indirectly through patient care, by GPs themselves, and by addressing wider systems. Future research is encouraged to explore the perspectives of other staff members and patient's experiences.</p>\u0000 </section>\u0000 </div>","PeriodicalId":51861,"journal":{"name":"Journal of General and Family Medicine","volume":"26 3","pages":"255-262"},"PeriodicalIF":1.8,"publicationDate":"2025-02-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/jgf2.774","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143871722","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Video review by utilizing asynchronous video communication platform 利用异步视频通信平台进行视频审核
IF 1.8
Journal of General and Family Medicine Pub Date : 2025-02-21 DOI: 10.1002/jgf2.70005
Yuki Otsuka MD, PhD, Eiko Mitsuda MD, Yukichika Yamamoto MD, Atsushi Kato MD, Mano Soshi MD, Masaya Higuchi MD, MPH, Mikako Obika MD, PhD, Fumio Otsuka MD, PhD, Tadayuki Hashimoto MD, MPH
{"title":"Video review by utilizing asynchronous video communication platform","authors":"Yuki Otsuka MD, PhD,&nbsp;Eiko Mitsuda MD,&nbsp;Yukichika Yamamoto MD,&nbsp;Atsushi Kato MD,&nbsp;Mano Soshi MD,&nbsp;Masaya Higuchi MD, MPH,&nbsp;Mikako Obika MD, PhD,&nbsp;Fumio Otsuka MD, PhD,&nbsp;Tadayuki Hashimoto MD, MPH","doi":"10.1002/jgf2.70005","DOIUrl":"https://doi.org/10.1002/jgf2.70005","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>Video review is widely recognized as an effective method for teaching communication; however, it can increase educators' workload and learners' stress.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>We utilized Tsucom, an online platform developed by BonBon, Inc., which enables asynchronous video communication instead of traditional styles. An 11-min and 42-s consultation video from a fifth-year resident was uploaded, and 10 physicians provided 30 text-based feedback.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>In this pilot survey, the utility and ease of use were rated 4.4 and 4.1 out of 5, respectively.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>While asynchronous online video reviews provided flexibility and greater participation, challenges remain, and further trials and evaluations were deemed necessary.</p>\u0000 </section>\u0000 </div>","PeriodicalId":51861,"journal":{"name":"Journal of General and Family Medicine","volume":"26 4","pages":"375-378"},"PeriodicalIF":1.8,"publicationDate":"2025-02-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/jgf2.70005","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144582417","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Early detection of cerebrospinal fluid/serum glucose ratio: A promising value for mortality prognosis in patients with acute bacterial meningitis 早期检测脑脊液/血清葡萄糖比:对急性细菌性脑膜炎患者死亡率预后的有希望的价值
IF 1.8
Journal of General and Family Medicine Pub Date : 2025-02-20 DOI: 10.1002/jgf2.70004
Nasrin Khodashenas MD, Rouzbeh Rajaei Ghafouri MD, Asghar Jafari Rouhi MD, Moloud Balafar MD
{"title":"Early detection of cerebrospinal fluid/serum glucose ratio: A promising value for mortality prognosis in patients with acute bacterial meningitis","authors":"Nasrin Khodashenas MD,&nbsp;Rouzbeh Rajaei Ghafouri MD,&nbsp;Asghar Jafari Rouhi MD,&nbsp;Moloud Balafar MD","doi":"10.1002/jgf2.70004","DOIUrl":"https://doi.org/10.1002/jgf2.70004","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background/Aims</h3>\u0000 \u0000 <p>Given that acute bacterial meningitis (ABM), as community-acquired meningitis, is considered a life-threatening medical emergency, early diagnosis and immediate onset of antibiotic therapy are of great importance. Here, we aimed to compare both the laboratory and glucometer assessment of cerebrospinal fluid (CSF)/serum glucose ratio in patients with suspected ABM. In addition, the prognostic value of the CSF/serum glucose ratio on the mortality rate was also evaluated.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>In this cross-sectional, single-center study, all demographic and clinical characteristics of patients who attended the emergency department were evaluated. A total of 200 patients with clinical suspicion of ABM underwent lumbar puncture (LP) and were simultaneously recruited for CSF and serum glucose measurement using both laboratory tests and a point-of-care glucometer device. Data analysis was performed using SPSS <i>ver</i>. 20.0.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Out of 200 suspected subjects with a mean age of 52.66 ± 6.64 years (male = 113, 56.5%), 23 patients (11.5%) were identified with confirmed ABM. The study findings showed a close correlation between the laboratory and glucometer-measured CSF/serum glucose ratio. The sensitivity and specificity of the glucose ratio measured by the laboratory test were 91.3% and 86.4%, respectively. A similar result was also observed by glucometer measurement (Sensitivity: 91.3%, Specificity: 89.3%, <i>p</i> &lt; 0.001). However, the mean time needed for CSF glucose measurement was significantly longer in the laboratory method compared to the glucometer-based assessment (<i>p</i> &lt; 0.0001). Notably, the CSF/serum glucose ratio was considerably lower in deceased patients (<i>n</i> = 9, <i>p</i> &lt; 0.05).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>Despite the similar accuracy of the CSF/serum glucose ratio using either a laboratory test or glucometer for ABM diagnosis, the present study highlighted that the laboratory turnaround time was significantly improved using a glucometer, which could be considered a reliable aid to the prognosis of mortality.</p>\u0000 </section>\u0000 </div>","PeriodicalId":51861,"journal":{"name":"Journal of General and Family Medicine","volume":"26 4","pages":"305-311"},"PeriodicalIF":1.8,"publicationDate":"2025-02-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/jgf2.70004","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144582463","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Extreme hypercalcemia secondary to parathyroid adenoma obscured by excessive coffee consumption and premature ventricular complexes 甲状旁腺瘤继发的极端高钙血症被过量的咖啡摄入和过早的心室复合物所掩盖
IF 1.8
Journal of General and Family Medicine Pub Date : 2025-02-14 DOI: 10.1002/jgf2.754
Yuval Avidan MD, Sameer Kassem MD, PhD
{"title":"Extreme hypercalcemia secondary to parathyroid adenoma obscured by excessive coffee consumption and premature ventricular complexes","authors":"Yuval Avidan MD,&nbsp;Sameer Kassem MD, PhD","doi":"10.1002/jgf2.754","DOIUrl":"https://doi.org/10.1002/jgf2.754","url":null,"abstract":"<p>Severe hypercalcemia has an arrhythmogenic effect. We present a case of a young male falsely diagnosed with premature ventricular complexes attributed to heavy coffee consumption, while symptoms and electrocardiographic findings of hypercalcemia were disregarded. Delayed work-up identified extreme hypercalcemia, and subsequently, parathyroid adenoma was diagnosed. Medical and surgical management resulted in complete resolution. The misdiagnosis led to a substantial diagnostic delay.</p>","PeriodicalId":51861,"journal":{"name":"Journal of General and Family Medicine","volume":"26 3","pages":"263-266"},"PeriodicalIF":1.8,"publicationDate":"2025-02-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/jgf2.754","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143871521","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Eosinophilic enteritis: A case for awareness among primary care physicians 嗜酸性粒细胞肠炎:一个病例的认识,在初级保健医生
IF 1.8
Journal of General and Family Medicine Pub Date : 2025-02-14 DOI: 10.1002/jgf2.70003
Kimitoshi Kubo MD, PhD, Issei Ashida MD, Noriko Kimura MD, PhD
{"title":"Eosinophilic enteritis: A case for awareness among primary care physicians","authors":"Kimitoshi Kubo MD, PhD,&nbsp;Issei Ashida MD,&nbsp;Noriko Kimura MD, PhD","doi":"10.1002/jgf2.70003","DOIUrl":"https://doi.org/10.1002/jgf2.70003","url":null,"abstract":"<p>In making a presumptive diagnosis of eosinophilic enteritis prompting specialist referral, primary care physicians are advised to focus on patients' medical history, medication history, clinical course, and blood tests, while bearing in mind that a definitive diagnosis of eosinophilic enteritis requires a histopathological assessment of biopsy specimens obtained during endoscopy. Colonoscopic findings in eosinophilic enteritis of this case included redness, erosion, and edema in the ileum.\u0000 <figure>\u0000 <div><picture>\u0000 <source></source></picture><p></p>\u0000 </div>\u0000 </figure></p>","PeriodicalId":51861,"journal":{"name":"Journal of General and Family Medicine","volume":"26 4","pages":"365-367"},"PeriodicalIF":1.8,"publicationDate":"2025-02-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/jgf2.70003","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144582093","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
An observational study to determine the optimal physical evaluation site for detecting anemia 一项确定检测贫血的最佳物理评价部位的观察性研究
IF 1.8
Journal of General and Family Medicine Pub Date : 2025-02-14 DOI: 10.1002/jgf2.776
Ken Horibata MD, PhD, Seigo Kondo MD, Shuji Hashimoto MD, Yousuke Takemura MD, PhD
{"title":"An observational study to determine the optimal physical evaluation site for detecting anemia","authors":"Ken Horibata MD, PhD,&nbsp;Seigo Kondo MD,&nbsp;Shuji Hashimoto MD,&nbsp;Yousuke Takemura MD, PhD","doi":"10.1002/jgf2.776","DOIUrl":"https://doi.org/10.1002/jgf2.776","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>Clinical pallor has traditionally served as a screening tool for anemia; however, its assessment lacks objectivity. Therefore, this study aimed to investigate the correlation between skin and mucosal color, as measured by a spectrophotometer, and venous hemoglobin (Hb) values, to identify the optimal anatomical assessment site for detecting anemia.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>A cross-sectional design. Ninety-two adult Japanese outpatients participated in the study. Using a spectrophotometer, the color of the lip and conjunctiva was measured indirectly, while the color of the nail, palm, and inside of the upper arm was measured directly. Colors were quantified using the <i>L</i>*<i>a</i>*<i>b</i>* color scale. This is an international color scale, where the <i>L</i>* value is an index of brightness, <i>a</i>* value is red/green, and <i>b</i>* value is yellow/blue. The color difference (<i>Δ</i><i>E</i>*) was employed to evaluate the discriminability of anemia identification across different assessment sites. Additionally, Hb values were recorded, with anemia defined as Hb &lt;12.0 g/dL.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>The <i>a</i>* values of the lip, conjunctiva, palm, and arm exhibited a positive correlation with Hb values and were significantly lower in the anemic group. While the <i>Δ</i><i>E</i>* levels for the conjunctiva and lip were readily discernible by the human eye when comparing the normal and anemic groups, recognition at this level proved challenging for other sites.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>The conjunctiva and lip demonstrate potential suitability for visual diagnosis of anemia. In the nail, palm, and arm, anemia detection may require highly trained observation. Consequently, reliance on these sites for anemia diagnosis may lead to potential oversight.</p>\u0000 </section>\u0000 </div>","PeriodicalId":51861,"journal":{"name":"Journal of General and Family Medicine","volume":"26 3","pages":"246-254"},"PeriodicalIF":1.8,"publicationDate":"2025-02-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/jgf2.776","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143871522","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Ulcerative colitis after Salmonella infection 沙门氏菌感染后的溃疡性结肠炎
IF 1.8
Journal of General and Family Medicine Pub Date : 2025-02-14 DOI: 10.1002/jgf2.70001
Toshihiko Kakiuchi MD, PhD, Masato Yoshiura MD
{"title":"Ulcerative colitis after Salmonella infection","authors":"Toshihiko Kakiuchi MD, PhD,&nbsp;Masato Yoshiura MD","doi":"10.1002/jgf2.70001","DOIUrl":"https://doi.org/10.1002/jgf2.70001","url":null,"abstract":"&lt;p&gt;An 11-year-old boy was referred to our hospital with intestinal salmonellosis (group O4), presenting with severe abdominal pain, diarrhea, hematochezia, and high fever. The symptoms promptly resolved with tosufloxacin, and the stool cultures became negative continuously. However, hematochezia persisted, and the fecal calprotectin (FCP) level was 2250 mg/kg. One month after the onset, total colonoscopy (TCS) revealed mucosal redness and edema with small aphthae in the sigmoid colon (Figure 1A), indicating pathologically nonspecific inflammation (Figure 1B). Conversely, no lesions were observed in the rectum (Figure 1C). Subsequently, the grossly bloody stool disappeared completely within 2 weeks after the first TCS; however, the fecal occult blood test (FOBT) remained positive, the FCP level remained high (2930 mg/kg) despite the absence of gastrointestinal symptoms, and only tenesmus appeared 1 year after the first TCS. A second TCS for the tenesmus revealed diffuse redness, erosions, and granular mucosa with a loss of vascular permeability from the sigmoid colon to the rectum (Figure 2A,B). Pathological examination revealed inflammatory cell infiltration, basal plasmacytosis, decreased goblet cells, and cryptitis, consistent with ulcerative colitis (UC) (Figure 2C). Based on these findings, oral intake of 5-aminosalicylate and topical steroids was started, which resolved the tenesmus immediately and normalized the FOBT and FCP levels promptly.&lt;/p&gt;&lt;p&gt;Salmonella infection can trigger UC development by causing permanent changes in the intestinal microbiota, disrupting the epithelial barrier, and altering the intestinal immune response.&lt;span&gt;&lt;sup&gt;1, 2&lt;/sup&gt;&lt;/span&gt; Salmonella infection is associated with an 8–10-fold increase in the risk of UC development within the following year.&lt;span&gt;&lt;sup&gt;3&lt;/sup&gt;&lt;/span&gt; In this case, the lesions skipped the rectum in the first TCS, which is a characteristic finding of Salmonella enteritis, in contrast to the lesions that continued from the rectum in UC. Subsequently, no gastrointestinal symptoms were observed; however, tenesmus was observed 1 year later, and UC was diagnosed endoscopically and pathologically in a second TCS. Although the onset time of UC is difficult to confirm, UC certainly developed after Salmonella enteritis. Therefore, when persistent intestinal symptoms occur after an episode of intestinal salmonellosis, the possibility of UC should always be considered.&lt;/p&gt;&lt;p&gt;&lt;b&gt;Toshihiko Kakiuchi:&lt;/b&gt; Conceptualization; investigation; writing – original draft; methodology; validation; supervision. &lt;b&gt;Masato Yoshiura:&lt;/b&gt; Investigation; writing – review and editing.&lt;/p&gt;&lt;p&gt;The authors did not receive support from any organization for the submitted work.&lt;/p&gt;&lt;p&gt;The authors declare no conflict of interest.&lt;/p&gt;&lt;p&gt;Ethics approval statement: We confirm that written informed consent was obtained from the patient's parents for publication of the clinical images and accompanying text. The patient's parents was info","PeriodicalId":51861,"journal":{"name":"Journal of General and Family Medicine","volume":"26 4","pages":"363-364"},"PeriodicalIF":1.8,"publicationDate":"2025-02-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/jgf2.70001","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144582094","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Home-based collaborative management of bullous pemphigoid with delayed seropositive conversion of anti-BP180-NC16a antibody 抗bp180 - nc16a抗体血清阳性转化延迟的大疱性类天疱疮家庭协同治疗
IF 1.8
Journal of General and Family Medicine Pub Date : 2025-02-13 DOI: 10.1002/jgf2.70002
Hiromitsu Yamashita MD, MPH, Takayuki Ando MD, MPH, PhD, Hirohisa Fujikawa MD, PhD, Masayoshi Shiota MD
{"title":"Home-based collaborative management of bullous pemphigoid with delayed seropositive conversion of anti-BP180-NC16a antibody","authors":"Hiromitsu Yamashita MD, MPH,&nbsp;Takayuki Ando MD, MPH, PhD,&nbsp;Hirohisa Fujikawa MD, PhD,&nbsp;Masayoshi Shiota MD","doi":"10.1002/jgf2.70002","DOIUrl":"https://doi.org/10.1002/jgf2.70002","url":null,"abstract":"<p>We report the case of an 82-year-old male with a history of multiple cerebral infarctions who developed bullous pemphigoid while receiving home-based care. Anti-BP180-NC16a antibody was initially negative, but later became positive as the disease severity worsened. The patient was successfully managed at home through a collaborative effort between a home-visiting physician (general practitioner), dermatologist, nursing staff, and pharmacists. This case highlights the value of reevaluating anti-BP180-NC16a antibody levels and the feasibility of home-based care for severe bullous pemphigoid in bedridden patients.</p>","PeriodicalId":51861,"journal":{"name":"Journal of General and Family Medicine","volume":"26 4","pages":"355-358"},"PeriodicalIF":1.8,"publicationDate":"2025-02-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/jgf2.70002","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144582220","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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