Home-based collaborative management of bullous pemphigoid with delayed seropositive conversion of anti-BP180-NC16a antibody

Abstract

We report the case of an 82-year-old male with a history of multiple cerebral infarctions who developed bullous pemphigoid while receiving home-based care. Anti-BP180-NC16a antibody was initially negative, but later became positive as the disease severity worsened. The patient was successfully managed at home through a collaborative effort between a home-visiting physician (general practitioner), dermatologist, nursing staff, and pharmacists. This case highlights the value of reevaluating anti-BP180-NC16a antibody levels and the feasibility of home-based care for severe bullous pemphigoid in bedridden patients.