{"title":"抗bp180 - nc16a抗体血清阳性转化延迟的大疱性类天疱疮家庭协同治疗","authors":"Hiromitsu Yamashita MD, MPH, Takayuki Ando MD, MPH, PhD, Hirohisa Fujikawa MD, PhD, Masayoshi Shiota MD","doi":"10.1002/jgf2.70002","DOIUrl":null,"url":null,"abstract":"<p>We report the case of an 82-year-old male with a history of multiple cerebral infarctions who developed bullous pemphigoid while receiving home-based care. Anti-BP180-NC16a antibody was initially negative, but later became positive as the disease severity worsened. The patient was successfully managed at home through a collaborative effort between a home-visiting physician (general practitioner), dermatologist, nursing staff, and pharmacists. This case highlights the value of reevaluating anti-BP180-NC16a antibody levels and the feasibility of home-based care for severe bullous pemphigoid in bedridden patients.</p>","PeriodicalId":51861,"journal":{"name":"Journal of General and Family Medicine","volume":"26 4","pages":"355-358"},"PeriodicalIF":2.3000,"publicationDate":"2025-02-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/jgf2.70002","citationCount":"0","resultStr":"{\"title\":\"Home-based collaborative management of bullous pemphigoid with delayed seropositive conversion of anti-BP180-NC16a antibody\",\"authors\":\"Hiromitsu Yamashita MD, MPH, Takayuki Ando MD, MPH, PhD, Hirohisa Fujikawa MD, PhD, Masayoshi Shiota MD\",\"doi\":\"10.1002/jgf2.70002\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p>We report the case of an 82-year-old male with a history of multiple cerebral infarctions who developed bullous pemphigoid while receiving home-based care. Anti-BP180-NC16a antibody was initially negative, but later became positive as the disease severity worsened. The patient was successfully managed at home through a collaborative effort between a home-visiting physician (general practitioner), dermatologist, nursing staff, and pharmacists. This case highlights the value of reevaluating anti-BP180-NC16a antibody levels and the feasibility of home-based care for severe bullous pemphigoid in bedridden patients.</p>\",\"PeriodicalId\":51861,\"journal\":{\"name\":\"Journal of General and Family Medicine\",\"volume\":\"26 4\",\"pages\":\"355-358\"},\"PeriodicalIF\":2.3000,\"publicationDate\":\"2025-02-13\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://onlinelibrary.wiley.com/doi/epdf/10.1002/jgf2.70002\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of General and Family Medicine\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://onlinelibrary.wiley.com/doi/10.1002/jgf2.70002\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"MEDICINE, GENERAL & INTERNAL\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of General and Family Medicine","FirstCategoryId":"1085","ListUrlMain":"https://onlinelibrary.wiley.com/doi/10.1002/jgf2.70002","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"MEDICINE, GENERAL & INTERNAL","Score":null,"Total":0}
Home-based collaborative management of bullous pemphigoid with delayed seropositive conversion of anti-BP180-NC16a antibody
We report the case of an 82-year-old male with a history of multiple cerebral infarctions who developed bullous pemphigoid while receiving home-based care. Anti-BP180-NC16a antibody was initially negative, but later became positive as the disease severity worsened. The patient was successfully managed at home through a collaborative effort between a home-visiting physician (general practitioner), dermatologist, nursing staff, and pharmacists. This case highlights the value of reevaluating anti-BP180-NC16a antibody levels and the feasibility of home-based care for severe bullous pemphigoid in bedridden patients.