Eye and Brain最新文献_第9页

Orbital Apex Syndrome: A Review. 眶尖综合征:综述。

IF 4.4

Eye and Brain Pub Date : 2019-12-12 eCollection Date: 2019-01-01 DOI: 10.2147/EB.S180190

Akshay Badakere, Preeti Patil-Chhablani

引用次数: 53

The Psychophysical Assessment of Hierarchical Magno-, Parvo- and Konio-Cellular Visual Stream Dysregulations in Migraineurs 偏头痛患者马格诺细胞、细小细胞和konio细胞视觉流失调的层次性心理生理评估

IF 4.4

Eye and Brain Pub Date : 2019-11-01 DOI: 10.2147/EB.S225171

M. F. Wesner, James N. R. Brazeau

{"title":"The Psychophysical Assessment of Hierarchical Magno-, Parvo- and Konio-Cellular Visual Stream Dysregulations in Migraineurs","authors":"M. F. Wesner, James N. R. Brazeau","doi":"10.2147/EB.S225171","DOIUrl":"https://doi.org/10.2147/EB.S225171","url":null,"abstract":"Introduction Although conscious, image-forming illusions have been noted in migraine, few studies have specifically sought to collectively evaluate the role of all three parallel visual processing streams in the retinogeniculostriate pathway involved with image-forming vision and their implications in the development of migraine symptoms. Methods We psychophysically assessed the functionality of the inferred magnocellular (MC), parvocellular (PC), and koniocellular (KC) streams at different hierarchical loci across three clinical groups: individuals who experience migraine with aura (MA; n=13), experience migraine without aura (MWO; n=14), and Controls (n=15). Participants completed four experiments: Experiment 1 designed to assess retinal short-wavelength-sensitive (S-) cone sensitivities; Experiment 2 intended to measure postretinal temporal and spatiochromatic contrast sensitivities; Experiment 3 intended to assess postretinal spatiotemporal achromatic contrast sensitivities; and Experiment 4 designed to measure thalamocortical color discriminations along the three cone-excitation axes. Results S-cone deficits were revealed with greater retinal areas being affected in MA compared to MWO participants. Findings across the four experiments suggest a prominent retinal locus of dysfunction in MA (lesser in MWO) with potential feedforward compensations occurring within the KC visual stream. Conclusion Complex, integrative network compensations need to be factored in when considering the dysregulating influences of migraine along the visual pathway.","PeriodicalId":51844,"journal":{"name":"Eye and Brain","volume":"11 1","pages":"49 - 62"},"PeriodicalIF":4.4,"publicationDate":"2019-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.2147/EB.S225171","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46064239","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Neuro-Ophthalmological Manifestations Of Septo-Optic Dysplasia: Current Perspectives. 视间隔发育不良的神经眼科表现：目前的展望。

IF 4.4

Eye and Brain Pub Date : 2019-10-18 eCollection Date: 2019-01-01 DOI: 10.2147/EB.S186307

Mario Ganau, Sibel Huet, Nikolaos Syrmos, Marco Meloni, Jayaratnam Jayamohan

引用次数: 24

Evidence to date: ranibizumab and its potential in the treatment of retinopathy of prematurity 迄今为止的证据：雷珠单抗及其在治疗早产儿视网膜病变中的潜力

IF 4.4

Eye and Brain Pub Date : 2019-08-23 DOI: 10.2147/EB.S189684

Samir N. Patel, M. Klufas

引用次数: 12

Neuro-ophthalmological manifestations of tuberous sclerosis: current perspectives 结节性硬化症的神经-眼科表现:目前的观点

IF 4.4

Eye and Brain Pub Date : 2019-06-01 DOI: 10.2147/EB.S186306

Michael J. Wan, Kathy Chan, B. Jastrzembski, Asim Ali

引用次数: 10

Giant cell arteritis: early diagnosis is key. 巨细胞动脉炎：早期诊断是关键。

IF 4.4

Eye and Brain Pub Date : 2019-01-17 eCollection Date: 2019-01-01 DOI: 10.2147/EB.S170388

Iyza F Baig, Alexis R Pascoe, Ashwini Kini, Andrew G Lee

引用次数: 0

Investigating possible retinal biomarkers of head trauma in Olympic boxers using optical coherence tomography. 利用光学相干断层扫描研究奥林匹克拳击手头部创伤可能的视网膜生物标志物。

IF 4.4

Eye and Brain Pub Date : 2018-12-14 eCollection Date: 2018-01-01 DOI: 10.2147/EB.S183042

Charmaine Childs, Lynne A Barker, Alex Md Gage, Mike Loosemore

{"title":"Investigating possible retinal biomarkers of head trauma in Olympic boxers using optical coherence tomography.","authors":"Charmaine Childs, Lynne A Barker, Alex Md Gage, Mike Loosemore","doi":"10.2147/EB.S183042","DOIUrl":"https://doi.org/10.2147/EB.S183042","url":null,"abstract":"Purpose: Changes to retina have been reported after a number of neurodegenerative conditions. The purpose of this study was to investigate retinal structures in Olympic boxers exposed to frequent head blows.Methods: Retinal imaging offers potential as a non-invasive biomarker of neuropathology. Macula and retinal nerve fiber layer (RNFL) thickness was measured using optical coherence tomography (OCT) in UK Olympic boxers attending two mandatory eye screening programs, 18 months apart. Data from the two eye screenings provide longitudinal data of retinal change over time. Sedentary healthy subjects (controls) without past or present history of concussion were also screened at the time of the second boxer screening to provide comparison of cross-sectional data.Results: Sixteen Olympic boxers aged 20-33 years and 20 sedentary healthy controls, aged 24-45 years, were recruited. Significant macula thickening was observed over time (18 months) in 75% of right and 50% of left eye sectors. For RNFL, left eye quadrants thickened. For right eye RNFL quadrants, thickening and thinning of this layer were observed. Cross-sectional results showed thinner macula sectors and RNFL quadrants in Olympic boxers compared to controls.Conclusion: Significant change to macula and RNFL densities, occurring over an 18 month interval is an unexpected finding in otherwise heathy elite sportsmen. In addition, macula and RNFL were thinner than healthy sedentary controls. OCT may prove clinically useful as a candidate retinal biomarker of neuropathological change after mild traumatic brain injury and/or repeat head blows.","PeriodicalId":51844,"journal":{"name":"Eye and Brain","volume":"10 ","pages":"101-110"},"PeriodicalIF":4.4,"publicationDate":"2018-12-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.2147/EB.S183042","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36806029","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 13

Optic nerve sheath meningiomas: prevalence, impact, and management strategies. 视神经鞘脑膜瘤:患病率，影响和管理策略。

IF 4.4

Eye and Brain Pub Date : 2018-10-24 eCollection Date: 2018-01-01 DOI: 10.2147/EB.S144345

Richard T Parker, Christopher A Ovens, Clare L Fraser, Chameen Samarawickrama

引用次数: 42

Curvilinear, symmetrical, and profound pigment deposition on the posterior lens capsule in a patient with bilateral pigmentary dispersion syndrome. 双侧色素分散综合征患者晶状体后囊呈曲线状、对称状、深度色素沉积。

IF 4.4

Eye and Brain Pub Date : 2018-09-13 eCollection Date: 2018-01-01 DOI: 10.2147/EB.S160999

Julia Canestraro, Jerome Sherman

{"title":"Curvilinear, symmetrical, and profound pigment deposition on the posterior lens capsule in a patient with bilateral pigmentary dispersion syndrome.","authors":"Julia Canestraro, Jerome Sherman","doi":"10.2147/EB.S160999","DOIUrl":"https://doi.org/10.2147/EB.S160999","url":null,"abstract":"Introduction: The classic presentation of pigmentary dispersion syndrome (PDS) often consists of midperipheral iris transillumination defects, Krukenberg's spindle, and dense homogeneous trabecular pigmentation. Other subtle, sometimes overlooked features include pigment on the lens zonules, pigment on the anterior lens capsule and pigment along the equator of the posterior lens capsule.Case: This unique presentation of PDS presented with bilateral, dense, oblique, and symmetrical pigment deposition along the posterior lens capsule that changed in shape, density, and extent over the span of 3 years.Discussion: There have been few reports in the literature that describe a central accumulation of pigment along the posterior lens capsule associated with PDS. There are reported cases of pigment deposition along the central aspect of the posterior lens capsule, some changing over time, although none were bilateral and symmetrical. There are suggestions that perhaps this central pigment deposition is related to a break in the ligament of Weiger, allowing communication between the posterior chamber and posterior lens capsule. This is a case in which curvilinear, symmetrical, and changing pigment deposition on the posterior lens capsule is suggestive of perhaps another key features of PDS.","PeriodicalId":51844,"journal":{"name":"Eye and Brain","volume":"10 ","pages":"79-84"},"PeriodicalIF":4.4,"publicationDate":"2018-09-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.2147/EB.S160999","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36525884","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 5

Effects of tDCS-like electrical stimulation on retinal ganglion cells. tdcs样电刺激对视网膜神经节细胞的影响。

IF 4.4

Eye and Brain Pub Date : 2018-08-27 eCollection Date: 2018-01-01 DOI: 10.2147/EB.S163914

Christianne E Strang, Mary Katherine Ray, Mary M Boggiano, Franklin R Amthor

{"title":"Effects of tDCS-like electrical stimulation on retinal ganglion cells.","authors":"Christianne E Strang, Mary Katherine Ray, Mary M Boggiano, Franklin R Amthor","doi":"10.2147/EB.S163914","DOIUrl":"https://doi.org/10.2147/EB.S163914","url":null,"abstract":"Purpose: Transcranial direct current stimulation (tDCS) has been studied in humans for its effects on enhancement of learning, amelioration of psychiatric disorders, and modification of other behaviors for over 50 years. Typical treatments involve injecting 2 mA current through scalp electrodes for 20 minutes, sometimes repeated weekly for two to five sessions. Little is known about the direct effects of tDCS at the neural circuit or the cellular level. This study assessed the effects of tDCS-like currents on the central nervous system by recording effects on retinal ganglion cell responsiveness using the rabbit retina eyecup preparation.Materials and methods: We examined changes in firing to On and Off light stimuli during and after brief applications of a range of currents and polarity and in different classes of ganglion cells.Results: The responses of Sustained cells were consistently suppressed during the first round of current application, but responses could be enhanced after subsequent rounds of stimulation. The observed first round suppression was independent of current polarity, amplitude, or number of trials. However, the light responses of Transient cells were more likely to be enhanced by negative currents and unaffected or suppressed by first round positive currents. Short-duration currents, that is, minutes, as low as 2.5 µA produced a remarkable persistency of firing changes, for up to 1.5 hours, after cessation of current.Conclusion: The results are consistent with postulated tDCS alteration of central nervous system function, which outlast the tDCS session and provide evidence for the isolated retina as a useful model to understand tDCS actions at the neuronal level.","PeriodicalId":51844,"journal":{"name":"Eye and Brain","volume":"10 ","pages":"65-78"},"PeriodicalIF":4.4,"publicationDate":"2018-08-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.2147/EB.S163914","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36488117","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 8