Optic nerve sheath meningiomas: prevalence, impact, and management strategies.

IF 3.1 Q1 OPHTHALMOLOGY

Eye and Brain Pub Date : 2018-10-24 eCollection Date: 2018-01-01 DOI:10.2147/EB.S144345

Richard T Parker, Christopher A Ovens, Clare L Fraser, Chameen Samarawickrama

引用次数: 42

Abstract

Optic nerve sheath meningiomas are rare benign neoplasms of the meninges surrounding the optic nerve. They are a significant cause of morbidity. While the mortality rate is practically zero, these tumors can blind or disfigure patients. Given that the clinical course can be variable, and treatment has the capacity to cause morbidity itself, the management of these patients can be difficult. We review the literature to discuss the prevalence of optic nerve sheath meningiomas, the association with neurofibromatosis type 2, natural history, and management options and strategies.

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视神经鞘脑膜瘤:患病率，影响和管理策略。

视神经鞘脑膜瘤是少见的视神经周围脑膜的良性肿瘤。它们是致病的重要原因。虽然死亡率几乎为零，但这些肿瘤可以使患者失明或毁容。鉴于临床过程可能是可变的，治疗本身就有可能导致发病率，因此对这些患者的管理可能是困难的。我们回顾文献，讨论视神经鞘脑膜瘤的患病率，与2型神经纤维瘤病的关系，自然病史，以及治疗方案和策略。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Eye and Brain OPHTHALMOLOGY-

CiteScore

7.90

自引率

2.30%

发文量

审稿时长

16 weeks

期刊介绍： Eye and Brain is an international, peer-reviewed, open access journal focusing on basic research, clinical findings, and expert reviews in the field of visual science and neuro-ophthalmology. The journal’s unique focus is the link between two well-known visual centres, the eye and the brain, with an emphasis on the importance of such connections. All aspects of clinical and especially basic research on the visual system are addressed within the journal as well as significant future directions in vision research and therapeutic measures. This unique journal focuses on neurological aspects of vision – both physiological and pathological. The scope of the journal spans from the cornea to the associational visual cortex and all the visual centers in between. Topics range from basic biological mechanisms to therapeutic treatment, from simple organisms to humans, and utilizing techniques from molecular biology to behavior. The journal especially welcomes primary research articles or review papers that make the connection between the eye and the brain. Specific areas covered in the journal include: Physiology and pathophysiology of visual centers, Eye movement disorders and strabismus, Cellular, biochemical, and molecular features of the visual system, Structural and functional organization of the eye and of the visual cortex, Metabolic demands of the visual system, Diseases and disorders with neuro-ophthalmic manifestations, Clinical and experimental neuro-ophthalmology and visual system pathologies, Epidemiological studies.