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Increasing Participation and Completion Rates in Questionnaire Surveys of Primary Care Patients: Cluster-Randomized Study. 提高初级保健患者问卷调查的参与率和完成率:分组随机研究
IF 1.9
Interactive Journal of Medical Research Pub Date : 2025-02-25 DOI: 10.2196/67981
Paul Sebo, Benoit Tudrej, Augustin Bernard, Bruno Delaunay, Alexandra Dupuy, Claire Malavergne, Hubert Maisonneuve
{"title":"Increasing Participation and Completion Rates in Questionnaire Surveys of Primary Care Patients: Cluster-Randomized Study.","authors":"Paul Sebo, Benoit Tudrej, Augustin Bernard, Bruno Delaunay, Alexandra Dupuy, Claire Malavergne, Hubert Maisonneuve","doi":"10.2196/67981","DOIUrl":"10.2196/67981","url":null,"abstract":"<p><strong>Background: </strong>Participation and completion rates in questionnaire-based surveys are often low.</p><p><strong>Objective: </strong>This study aims to assess participation and completion rates for a survey using paper and mixed mode questionnaires with patients recruited by research assistants in primary care waiting rooms.</p><p><strong>Methods: </strong>This cluster-randomized study, conducted in 2023 in France, involved 974 patients from 39 practices randomized into 4 groups: \"paper with incentive\" (n=251), \"paper without incentive\" (n=368), \"mixed mode with tablet\" (n=187), and \"mixed mode with QR code\" (n=168). Analyses compared the combined paper group with the 2 mixed mode groups and the \"paper with incentive\" and \"paper without incentive\" groups. Logistic regressions were used to analyze participation and completion rates.</p><p><strong>Results: </strong>Of the 974 patients recruited, 822 (women: 536/821, 65.3%; median age 52, IQR 37-68 years) agreed to participate (participation rate=84.4%), with no significant differences between groups. Overall, 806 patients (98.1%) answered all 48 questions. Completion rates were highest in the combined paper group (99.8%) compared to mixed mode groups (96.8% for paper or tablet, 93.3% for paper or QR code; P<.001). There was no significant difference in completion rates between the \"paper with incentive\" and \"paper without incentive\" groups (100% vs 99.7%).</p><p><strong>Conclusions: </strong>Recruiting patients in waiting rooms with research assistants resulted in high participation and completion rates across all groups. Mixed mode options did not enhance participation or completion rates but may offer logistical advantages. Future research should explore incentives and mixed-mode strategies in diverse settings.</p>","PeriodicalId":51757,"journal":{"name":"Interactive Journal of Medical Research","volume":"14 ","pages":"e67981"},"PeriodicalIF":1.9,"publicationDate":"2025-02-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11897665/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143505931","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comparing Digital Versus Face-to-Face Delivery of Systemic Psychotherapy Interventions: Systematic Review and Meta-Analysis of Randomized Controlled Trials.
IF 1.9
Interactive Journal of Medical Research Pub Date : 2025-02-24 DOI: 10.2196/46441
Pieter Erasmus, Moritz Borrmann, Jule Becker, Lars Kuchinke, Gunther Meinlschmidt
{"title":"Comparing Digital Versus Face-to-Face Delivery of Systemic Psychotherapy Interventions: Systematic Review and Meta-Analysis of Randomized Controlled Trials.","authors":"Pieter Erasmus, Moritz Borrmann, Jule Becker, Lars Kuchinke, Gunther Meinlschmidt","doi":"10.2196/46441","DOIUrl":"10.2196/46441","url":null,"abstract":"&lt;p&gt;&lt;strong&gt;Background: &lt;/strong&gt;As digital mental health delivery becomes increasingly prominent, a solid evidence base regarding its efficacy is needed.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Objective: &lt;/strong&gt;This study aims to synthesize evidence on the comparative efficacy of systemic psychotherapy interventions provided via digital versus face-to-face delivery modalities.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Methods: &lt;/strong&gt;We followed PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) guidelines for searching PubMed, Embase, Cochrane CENTRAL, CINAHL, PsycINFO, and PSYNDEX and conducting a systematic review and meta-analysis. We included randomized controlled trials comparing mental, behavioral, and somatic outcomes of systemic psychotherapy interventions using self- and therapist-guided digital versus face-to-face delivery modalities. The risk of bias was assessed with the revised Cochrane Risk of Bias tool for randomized trials. Where appropriate, we calculated standardized mean differences and risk ratios. We calculated separate mean differences for nonaggregated analysis.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Results: &lt;/strong&gt;We screened 3633 references and included 12 articles reporting on 4 trials (N=754). Participants were youths with poor diabetic control, traumatic brain injuries, increased risk behavior likelihood, and parents of youths with anorexia nervosa. A total of 56 outcomes were identified. Two trials provided digital intervention delivery via videoconferencing: one via an interactive graphic interface and one via a web-based program. In total, 23% (14/60) of risk of bias judgments were high risk, 42% (25/60) were some concerns, and 35% (21/60) were low risk. Due to heterogeneity in the data, meta-analysis was deemed inappropriate for 96% (54/56) of outcomes, which were interpreted qualitatively instead. Nonaggregated analyses of mean differences and CIs between delivery modalities yielded mixed results, with superiority of the digital delivery modality for 18% (10/56) of outcomes, superiority of the face-to-face delivery modality for 5% (3/56) of outcomes, equivalence between delivery modalities for 2% (1/56) of outcomes, and neither superiority of one modality nor equivalence between modalities for 75% (42/56) of outcomes. Consequently, for most outcome measures, no indication of superiority or equivalence regarding the relative efficacy of either delivery modality can be made at this stage. We further meta-analytically compared digital versus face-to-face delivery modalities for attrition (risk ratio 1.03, 95% CI 0.52-2.03; P=.93) and number of sessions attended (standardized mean difference -0.11; 95% CI -1.13 to -0.91; P=.83), finding no significant differences between modalities, while CIs falling outside the range of the minimal important difference indicate that equivalence cannot be determined at this stage.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Conclusions: &lt;/strong&gt;Evidence on digital and face-to-face modalities for systemic psychotherapy interventions is largely heterogeneous,","PeriodicalId":51757,"journal":{"name":"Interactive Journal of Medical Research","volume":"14 ","pages":"e46441"},"PeriodicalIF":1.9,"publicationDate":"2025-02-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11894358/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143494371","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Exploring Barriers to Patients' Progression in the Cardiac Rehabilitation Journey From Health Care Providers' Perspectives: Qualitative Study.
IF 1.9
Interactive Journal of Medical Research Pub Date : 2025-02-21 DOI: 10.2196/66164
Shri Harini Ramesh, Darwin Jull, Hélène Fournier, Fateme Rajabiyazdi
{"title":"Exploring Barriers to Patients' Progression in the Cardiac Rehabilitation Journey From Health Care Providers' Perspectives: Qualitative Study.","authors":"Shri Harini Ramesh, Darwin Jull, Hélène Fournier, Fateme Rajabiyazdi","doi":"10.2196/66164","DOIUrl":"10.2196/66164","url":null,"abstract":"<p><strong>Background: </strong>Cardiovascular diseases are one of the leading causes of mortality globally. Cardiac rehabilitation (CR) programs are crucial for patients recovering from cardiac events, as they help reduce the risk of recurrent events and support patient recovery. The patient's journey in CR spans the stages before, during, and after the program. Patients have to progress through each stage of CR programs successfully to complete the entire CR journey and get the full benefits of CR programs, but numerous barriers within this journey can hinder patient progression.</p><p><strong>Objective: </strong>This study aims to explore the barriers to progression at all stages of the CR patient journey from the perspectives of health care providers involved in CR care.</p><p><strong>Methods: </strong>This qualitative study involved semistructured interviews with health care providers involved in CR care from July 2023 to January 2024. A purposive maximal variation sampling method was used to target providers with diverse demographics and specialties. Snowball sampling was used to recruit participants, leveraging the existing networks of participants. Each interview lasted between 30 and 45 minutes. Interviews were recorded, transcribed verbatim, and analyzed using an inductive thematic analysis approach. Data analysis was conducted from August 2023 to February 2024.</p><p><strong>Results: </strong>Ten health care providers, comprising 7 females and 3 males, were interviewed. Their roles included physician, program director, nurse manager, clinical manager, nurse coordinator, nurse, physiotherapist, and kinesiologist. The analysis identified four overarching themes related to barriers to progression in the CR journey: (1) patients not being referred to CR programs, (2) patients not enrolling in CR programs, (3) patients dropping out of CR programs, and (4) patients' lack of adherence to lifestyle changes post-CR programs.</p><p><strong>Conclusions: </strong>In light of the growing interest in technological interventions in CR programs, we proposed 4 potential technological solutions to address the barriers to progression identified in our analysis. These solutions aim to provide a foundation for future research to guide the development of effective technologies and enhance patient progression within the CR journey.</p>","PeriodicalId":51757,"journal":{"name":"Interactive Journal of Medical Research","volume":"14 ","pages":"e66164"},"PeriodicalIF":1.9,"publicationDate":"2025-02-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11890148/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143473176","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Use of Clinical Public Databases in Hidradenitis Suppurativa Research.
IF 1.9
Interactive Journal of Medical Research Pub Date : 2025-02-18 DOI: 10.2196/70282
Xu Liu, Linghong Guo, Xian Jiang
{"title":"Use of Clinical Public Databases in Hidradenitis Suppurativa Research.","authors":"Xu Liu, Linghong Guo, Xian Jiang","doi":"10.2196/70282","DOIUrl":"10.2196/70282","url":null,"abstract":"<p><p>In this viewpoint, we argue that recent studies using clinical public databases have revolutionized our understanding of hidradenitis suppurativa (HS), a chronic inflammatory skin condition with significant impacts on patients' quality of life. Our key messages are as follows: (1) these databases enable large-scale studies integrating genetic, epidemiological, and clinical data, providing crucial insights into HS's genetic predispositions, comorbidities, and treatment outcomes; (2) findings highlight a strong genetic component, with mutations in the γ-secretase complex playing a key role in HS pathogenesis and shaping targeted therapies; (3) studies also reveal elevated risks for comorbidities like obesity, diabetes, cardiovascular disease, and systemic inflammation in patients with HS, with diet-driven inflammatory pathways potentially exacerbating disease severity; (4) while these databases offer unprecedented research opportunities, limitations such as data representativeness and quality must be considered; (5) nonetheless, their benefits outweigh potential drawbacks, allowing the identification of rare comorbidities, disease progression patterns, and personalized treatment strategies; and (6) increased funding for HS research is crucial to harness these databases' full potential, develop targeted therapies, and ultimately improve patient outcomes. As HS's impact is disproportionate to current research investments, we believe advocating for more resources and addressing database limitations will be key to advancing HS understanding and care.</p>","PeriodicalId":51757,"journal":{"name":"Interactive Journal of Medical Research","volume":"14 ","pages":"e70282"},"PeriodicalIF":1.9,"publicationDate":"2025-02-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11888110/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143450936","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
An Automated Clinical Laboratory Decision Support System for Test Utilization, Medical Necessity Verification, and Payment Processing. 用于测试使用、医疗需求验证和支付处理的自动化临床实验室决策支持系统。
IF 1.9
Interactive Journal of Medical Research Pub Date : 2025-02-11 DOI: 10.2196/46007
Safedin Beqaj, Rojeet Shrestha, Tim Hamill
{"title":"An Automated Clinical Laboratory Decision Support System for Test Utilization, Medical Necessity Verification, and Payment Processing.","authors":"Safedin Beqaj, Rojeet Shrestha, Tim Hamill","doi":"10.2196/46007","DOIUrl":"10.2196/46007","url":null,"abstract":"<p><p>Physicians could improve the efficiency of the health care system if a reliable resource were available to aid them in better understanding, selecting, and interpreting the diagnostic laboratory tests. It has been well established and widely recognized that (1) laboratory testing provides 70%-85% of the objective data that physicians use in the diagnosis and treatment of their patients; (2) orders for laboratory tests in the United States have increased, with an estimated volume of 4-5 billion tests per year; (3) there is a lack of user-friendly tools to guide physicians in their test selection and ordering; and (4) laboratory test overutilization and underutilization continue to represent a pervasive source of inefficiency in the health care system. These inappropriate test orders not only lead to slower or incorrect diagnoses for patients but also add a significant financial burden. In addition, many ordered tests are not reimbursed by Medicare because they are inappropriate for the medical condition or were ordered with the incorrect International Statistical Classification of Diseases and Related Health Problems, Tenth Revision diagnostic code, not meeting the medical necessity. Therefore, current clinical laboratory test ordering procedures experience a quality gap. Often, providers do not have access to an appropriate tool that uses evidence-based guidelines or algorithms to ensure that tests are not duplicated, overused, or underused. This viewpoint lays out the potential use of an automated laboratory clinical decision support system that helps providers order the right test for the right disease and documents the right reason or medical necessity to pay for the testing.</p>","PeriodicalId":51757,"journal":{"name":"Interactive Journal of Medical Research","volume":" ","pages":"e46007"},"PeriodicalIF":1.9,"publicationDate":"2025-02-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11862781/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142984782","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Perceptions and Experiences of Caregiver-Employees, Employers, and Health Care Professionals With Caregiver-Friendly Workplace Policy in Hong Kong: Thematic Analysis.
IF 1.9
Interactive Journal of Medical Research Pub Date : 2025-02-10 DOI: 10.2196/58528
Maggie Man-Sin Lee, Eng-Kiong Yeoh, Eliza Lai-Yi Wong, Xue Bai, Nelson Chun-Yiu Yeung, Catherine French, Henock Taddese
{"title":"Perceptions and Experiences of Caregiver-Employees, Employers, and Health Care Professionals With Caregiver-Friendly Workplace Policy in Hong Kong: Thematic Analysis.","authors":"Maggie Man-Sin Lee, Eng-Kiong Yeoh, Eliza Lai-Yi Wong, Xue Bai, Nelson Chun-Yiu Yeung, Catherine French, Henock Taddese","doi":"10.2196/58528","DOIUrl":"10.2196/58528","url":null,"abstract":"<p><strong>Background: </strong>Caregiver-employees (CEs) for older adults experience a high burden to fulfill their dual roles. Caregiver-friendly workplace policy (CFWP) has been used in many countries to balance employment and caregiving duties, but it is a relatively new concept in Hong Kong.</p><p><strong>Objective: </strong>This study explored the views and experiences of CEs, employers, and health care professionals regarding CFWP (specifically for older adult caregivers) in Hong Kong.</p><p><strong>Methods: </strong>This study explored the CFWP-related views and experiences in Hong Kong using 15 in-depth interviews with purposively sampled CEs for older adults, employers, and health care professionals.</p><p><strong>Results: </strong>Two context-related themes (\"lacking leadership\" and \"unfavorable culture\") were identified with thematic analysis. They explain the absence of CFWP in Hong Kong due to the lack of governmental and organizational leadership, and the additional burden experienced by CEs because of the working culture that underpins work-life separation, overprizing business interest, and unsympathetic corporate attitude. Implicit voice theory was applicable in explaining CEs' nondisclosure about their status at work due to potential risks. In addition, the two facilitation-related themes (\"role struggle\" and \"inadequate support\") identified in this study exhibit how the dual role had positive and negative spillover effects on each other and the inadequacy of social welfare and health care support systems.</p><p><strong>Conclusions: </strong>We strongly recommend exploring and adopting potential CFWP in Hong Kong, considering the complexity of factors identified in this study.</p>","PeriodicalId":51757,"journal":{"name":"Interactive Journal of Medical Research","volume":"14 ","pages":"e58528"},"PeriodicalIF":1.9,"publicationDate":"2025-02-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11851026/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143391967","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Process Evaluations of Interventions for the Prevention of Type 2 Diabetes in Women With Gestational Diabetes Mellitus: Systematic Review.
IF 1.9
Interactive Journal of Medical Research Pub Date : 2025-02-06 DOI: 10.2196/51718
Iklil Iman Mohd Sa'id, Natasha Hotung, Madeleine Benton, Iliatha Papachristou Nadal, Anisah Baharom, Matthew Prina, Barakatun Nisak Mohd Yusof, Kimberley Goldsmith, Samantha Birts, Ching Siew Mooi, Angus Forbes, Khalida Ismail, Boon How Chew
{"title":"Process Evaluations of Interventions for the Prevention of Type 2 Diabetes in Women With Gestational Diabetes Mellitus: Systematic Review.","authors":"Iklil Iman Mohd Sa'id, Natasha Hotung, Madeleine Benton, Iliatha Papachristou Nadal, Anisah Baharom, Matthew Prina, Barakatun Nisak Mohd Yusof, Kimberley Goldsmith, Samantha Birts, Ching Siew Mooi, Angus Forbes, Khalida Ismail, Boon How Chew","doi":"10.2196/51718","DOIUrl":"10.2196/51718","url":null,"abstract":"&lt;p&gt;&lt;strong&gt;Background: &lt;/strong&gt;Gestational diabetes mellitus (GDM) is characterized by hyperglycemia in pregnancy and typically resolves after birth. Women with GDM have an increased risk of developing type 2 diabetes mellitus (T2DM) later in life compared to those with normoglycemic pregnancy. While diabetes prevention interventions (DPIs) have been developed to delay or prevent the onset of T2DM, few studies have provided process evaluation (PE) data to assess the mechanisms of impact, quality of implementation, or contextual factors that may influence the effectiveness of the intervention.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Objective: &lt;/strong&gt;This study aims to identify and evaluate PE data and how these link to outcomes of randomized controlled trials (RCTs) of T2DM prevention interventions for women with GDM.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Methods: &lt;/strong&gt;A systematic review was conducted to identify studies published from 2005 to 2020 aiming to capture the most recent DPIs. Five electronic bibliographic databases (Cochrane Library, Cochrane Collaboration Registry of Controlled Trials, Embase, PubMed, and MEDLINE) were searched to identify relevant studies. Inclusion criteria were published (peer-reviewed) RCTs of DPIs in women with a current diagnosis or history of GDM. Exclusion criteria were studies not published in English; studies where the target population was women who had a family history of T2D or women who were menopausal or postmenopausal; and gray literature, including abstracts in conference proceedings. The Medical Research Council's PE framework of complex interventions was used to identify key PE components. The Mixed Method Appraisal Tool was used to assess the quality of included studies.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Results: &lt;/strong&gt;A total of 24 studies were included; however, only 5 studies explicitly reported a PE theoretical framework. The studies involved 3 methods of intervention delivery, including in person (n=7), digital (n=7), and hybrid (n=9). Two of the studies conducted pilot RCTs assessing the feasibility and acceptability of their interventions, including recruitment, participation, retention, program implementation, adherence, and satisfaction, and 1 study assessed the efficacy of a questionnaire to promote food and vegetable intake. While most studies linked PE data with study outcomes, it was unclear which of the reported PE components were specifically linked to the positive outcomes.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Conclusions: &lt;/strong&gt;While the Medical Research Council's framework is a valuable source for conducting systematic reviews on PEs, it has been criticized for lacking practical advice on how to conduct them. The lack of information on PE frameworks in our review also made it difficult to categorize individual PE components against the framework. We need clearer guidance and robust frameworks for conducting PEs for the development and reporting of DPIs for women with GDM.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Trial registration: &lt;/strong&gt;PROSPERO International Prospective Register","PeriodicalId":51757,"journal":{"name":"Interactive Journal of Medical Research","volume":"14 ","pages":"e51718"},"PeriodicalIF":1.9,"publicationDate":"2025-02-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11843062/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143257243","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Correlation Between Objective Habit Metrics and Objective Medication Adherence: Retrospective Study of 15,818 Participants From Clinical Studies.
IF 1.9
Interactive Journal of Medical Research Pub Date : 2025-02-06 DOI: 10.2196/63987
Antoine Pironet, L Alison Phillips, Bernard Vrijens
{"title":"Correlation Between Objective Habit Metrics and Objective Medication Adherence: Retrospective Study of 15,818 Participants From Clinical Studies.","authors":"Antoine Pironet, L Alison Phillips, Bernard Vrijens","doi":"10.2196/63987","DOIUrl":"10.2196/63987","url":null,"abstract":"<p><strong>Background: </strong>Medication adherence, or how patients take their medication as prescribed, is suboptimal worldwide. Improving medication-taking habit might be an effective way to improve medication adherence. However, habit is difficult to quantify, and conventional habit metrics are self-reported, with recognized limitations. Recently, several objective habit metrics have been proposed, based on objective medication-taking data.</p><p><strong>Objective: </strong>We aim to explore the correlation between objective habit metrics and objective medication adherence on a large dataset.</p><p><strong>Methods: </strong>The Medication Event Monitoring System Adherence Knowledge Center, a database of anonymized electronic medication intake data from ambulant participants enrolled in past clinical studies, was used as the data source. Electronic medication intake data from participants following a once-daily regimen and monitored for 14 days or more were used. Further, two objective habit metrics were computed from each participant's medication intake history: (1) SD of the hour of intake, representing daily variability in the timing of medication intakes, and (2) weekly cross-correlation, representing weekly consistency in the timing of medication intakes. The implementation component of medication adherence was quantified using (1) the proportion of doses taken and (2) the proportion of correct days.</p><p><strong>Results: </strong>A total of 15,818 participants met the criteria. These participants took part in 108 clinical studies mainly focused on treatments for hypertension (n=4737, 30%) and osteoporosis (n=3353, 21%). The SD of the hour of intake was significantly negatively correlated with the 2 objective adherence metrics: proportion of correct days (Spearman correlation coefficient, ρ<sub>S</sub>=-0.62, P<.001) and proportion of doses taken (ρ<sub>S</sub>=-0.09, P<.001). The weekly cross-correlation was significantly positively correlated with the 2 objective adherence metrics: proportion of correct days (ρ<sub>S</sub>=0.55, P<.001) and proportion of doses taken (ρ<sub>S</sub>=0.32, P<.001). A lower daily or weekly variability in the timing of medication intakes is thus associated with better medication adherence. However, no variability is not the norm, as only 3.6% of participants have 95% of their intakes in a 1-hour window. Among the numerous factors influencing medication adherence, habit strength is an important one as it explains over 30% of the variance in medication adherence.</p><p><strong>Conclusions: </strong>Objective habit metrics are correlated to objective medication adherence. Such objective habit metrics can be used to monitor patients and identify those who may benefit from habit-building support.</p>","PeriodicalId":51757,"journal":{"name":"Interactive Journal of Medical Research","volume":"14 ","pages":"e63987"},"PeriodicalIF":1.9,"publicationDate":"2025-02-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11843050/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143366727","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Evolution of Artificial Intelligence in Medical Education From 2000 to 2024: Bibliometric Analysis.
IF 1.9
Interactive Journal of Medical Research Pub Date : 2025-01-30 DOI: 10.2196/63775
Rui Li, Tong Wu
{"title":"Evolution of Artificial Intelligence in Medical Education From 2000 to 2024: Bibliometric Analysis.","authors":"Rui Li, Tong Wu","doi":"10.2196/63775","DOIUrl":"10.2196/63775","url":null,"abstract":"<p><strong>Background: </strong>Incorporating artificial intelligence (AI) into medical education has gained significant attention for its potential to enhance teaching and learning outcomes. However, it lacks a comprehensive study depicting the academic performance and status of AI in the medical education domain.</p><p><strong>Objective: </strong>This study aims to analyze the social patterns, productive contributors, knowledge structure, and clusters since the 21st century.</p><p><strong>Methods: </strong>Documents were retrieved from the Web of Science Core Collection database from 2000 to 2024. VOSviewer, Incites, and Citespace were used to analyze the bibliometric metrics, which were categorized by country, institution, authors, journals, and keywords. The variables analyzed encompassed counts, citations, H-index, impact factor, and collaboration metrics.</p><p><strong>Results: </strong>Altogether, 7534 publications were initially retrieved and 2775 were included for analysis. The annual count and citation of papers exhibited exponential trends since 2018. The United States emerged as the lead contributor due to its high productivity and recognition levels. Stanford University, Johns Hopkins University, National University of Singapore, Mayo Clinic, University of Arizona, and University of Toronto were representative institutions in their respective fields. Cureus, JMIR Medical Education, Medical Teacher, and BMC Medical Education ranked as the top four most productive journals. The resulting heat map highlighted several high-frequency keywords, including performance, education, AI, and model. The citation burst time of terms revealed that AI technologies shifted from imaging processing (2000), augmented reality (2013), and virtual reality (2016) to decision-making (2020) and model (2021). Keywords such as mortality and robotic surgery persisted into 2023, suggesting the ongoing recognition and interest in these areas.</p><p><strong>Conclusions: </strong>This study provides valuable insights and guidance for researchers who are interested in educational technology, as well as recommendations for pioneering institutions and journal submissions. Along with the rapid growth of AI, medical education is expected to gain much more benefits.</p>","PeriodicalId":51757,"journal":{"name":"Interactive Journal of Medical Research","volume":"14 ","pages":"e63775"},"PeriodicalIF":1.9,"publicationDate":"2025-01-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11826936/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143069601","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Clinicians' Guide to Large Language Models: A General Perspective With a Focus on Hallucinations.
IF 1.9
Interactive Journal of Medical Research Pub Date : 2025-01-28 DOI: 10.2196/59823
Dimitri Roustan, François Bastardot
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