{"title":"Patient-Reported Quality of Life in Lung Transplantation: Prospective Cohort Study.","authors":"Peng Li, Jiawei Wang, Hongyi Wang, Shuo Li, Lei Wang, Shan Gao, Chunxiao Hu, Guangjian Zhang","doi":"10.2196/86211","DOIUrl":"10.2196/86211","url":null,"abstract":"<p><strong>Background: </strong>Lung transplantation (LTx) is an established treatment for patients with end-stage lung diseases and can substantially improve survival. However, posttransplant recovery involves complex physical, psychological, and functional challenges, making quality of life (QoL) an important outcome beyond survival alone. Evidence on early longitudinal QoL changes after LTx remains limited, particularly in Chinese recipients and when assessed using disease-specific patient-reported outcome instruments.</p><p><strong>Objective: </strong>This study aimed to assess QoL and track its longitudinal changes in patients who underwent LTx using a disease-specific patient-reported outcome instrument.</p><p><strong>Methods: </strong>This single-center prospective cohort study screened 66 patients for enrollment who underwent LTx at the Xi'an Jiaotong University Lung Transplantation Center in China from June 2023 to December 2025. QoL was assessed using the Chinese version of the Lung Transplant Quality of Life questionnaire at baseline (preoperative) and serially at 1, 2, 3, 4, 5, and 6 months after surgery. The Lung Transplant Quality of Life questionnaire comprises 40 items across 7 domains, and each domain score was calculated as the item mean (range 0-4). Random-intercept linear mixed models (LMMs) with both categorical and linear time specifications were fitted separately for each domain to evaluate longitudinal changes, accounting for repeated measures and incomplete follow-up under the missing at random assumption.</p><p><strong>Results: </strong>A total of 203 interviews from 51 eligible patients were included in this study, with a median of 5 (IQR 2-6) interviews for each patient. LMM analysis revealed significant overall time effects in 6 of 7 domains (likelihood ratio test: P<.01 in all cases). Health perceptions showed the earliest and largest improvement (LMM-adjusted mean difference [MD] -1.58 at month 6; β=-0.23 points per month; P<.001), followed by respiratory symptoms (MD -0.95 at month 6; β=-0.15 per month), anxiety and depression (MD -0.82 at month 6; β=-0.13 per month), digestive symptoms (MD -0.50 at month 6; β=-0.10 per month), and cognitive limitations (MD -0.51 at month 6; β=-0.09 per month; P<.001 in all cases). Global well-being was the only domain with a positive trajectory (MD 1.18 at month 6; β=0.13 per month; P=.002), with significant improvement already evident at month 1 (MD 0.71; P=.23).</p><p><strong>Conclusions: </strong>LTx significantly improved QoL in patients with end-stage lung diseases, with the most substantial gains in health perceptions and respiratory symptoms. Patient-reported outcome-based monitoring can capture clinically meaningful QoL changes and should be integrated into routine posttransplant care to identify critical intervention time points and optimize long-term recovery.</p>","PeriodicalId":51757,"journal":{"name":"Interactive Journal of Medical Research","volume":"15 ","pages":"e86211"},"PeriodicalIF":3.3,"publicationDate":"2026-08-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13457444/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148708485","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Correction: Digital Literacy and Interpersonal Trust as Predictors of Willingness to Share Patient-Generated Health Data Among Korean Internet Users: Cross-Sectional Study Using Privacy Calculus and Communication Privacy Management Theories.","authors":"Dongsu Lee, Wonseuk Jang","doi":"10.2196/103310","DOIUrl":"10.2196/103310","url":null,"abstract":"","PeriodicalId":51757,"journal":{"name":"Interactive Journal of Medical Research","volume":"15 ","pages":"e103310"},"PeriodicalIF":3.3,"publicationDate":"2026-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13427337/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148649773","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Hooi Swang Cheng, Yi Wang, Sharon Hui Xuan Tan, Ian Yi Han Ang
{"title":"Sociodemographic and Health-Risk Determinants of COVID-19 Vaccine Booster Preferences and Willingness to Pay in Singapore: Discrete Choice Experiment.","authors":"Hooi Swang Cheng, Yi Wang, Sharon Hui Xuan Tan, Ian Yi Han Ang","doi":"10.2196/87909","DOIUrl":"10.2196/87909","url":null,"abstract":"<p><strong>Background: </strong>Waning immunity and recurring COVID-19 waves point to the importance of sustained booster vaccination strategies. With repeated boosters needed to sustain population-level immunity, evaluating public preferences for COVID-19 booster vaccination is important for informing future vaccination strategies, as changing perceptions of urgency, threat, and motivation may alter willingness to receive vaccine boosters compared with initial uptake.</p><p><strong>Objective: </strong>This study aimed to explore the public's stated preferences and implicit willingness to pay for COVID-19 vaccine boosters in Singapore and to identify the sociodemographic factors and health-risk acceptance profiles associated with these outcomes.</p><p><strong>Methods: </strong>A discrete choice experiment survey was conducted among the general population in Singapore, recruited from an online panel in June 2022. Discrete choice experiment scenarios presented hypothetical scenarios varying by booster characteristics, including effectiveness, protection duration, and cost, and risks of COVID-19 infection, hospitalization, and death. A 2-stage discrete choice design was used: participants first selected between 2 hypothetical scenarios and then reported real-life booster acceptance of their chosen option. A mixed logit model was used for analyses. We also estimated implicit willingness to pay for vaccine boosters, as well as assessed the associations of sociodemographic factors and health-risk profiles with booster acceptance or hesitancy.</p><p><strong>Results: </strong>A total of 1567 participants were included in the analysis. Overall, respondents preferred boosters that offered a longer duration of protection, particularly under higher risks of COVID-19 infection and death. Respondents were willing to pay S$1.43 for every percentage-point increase in booster effectiveness, S$4.95 (S$1=US $0.77 as of July 10, 2026) per additional month of protection, and an additional S$55.23 for a vaccine booster under the hypothetical worst-case scenario of COVID-19. Younger adults, women, individuals of non-Chinese ethnicity, those without children, people with higher socioeconomic status, individuals who had received 2 or fewer COVID-19 vaccine doses, and those with chronic conditions or on chronic disease medication were more likely to receive a booster. On the other hand, older adults, individuals with lower education or socioeconomic status, those with prior COVID-19 infection, and those exhibiting higher health-risk acceptance were less likely to accept booster vaccination.</p><p><strong>Conclusions: </strong>Our findings demonstrate how vaccine attributes, sociodemographic factors, and health-risk attitudes influence booster acceptance. These insights can guide policymakers in tailoring strategies and communication efforts that address population needs and behavioral drivers to improve booster uptake, address hesitancy, and support sustainable long-term ","PeriodicalId":51757,"journal":{"name":"Interactive Journal of Medical Research","volume":"15 ","pages":"e87909"},"PeriodicalIF":3.3,"publicationDate":"2026-07-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13418094/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148622506","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Kátia M Avena, Ana Paula A Brito, Luiz F Quintanilha, Mariana Araújo-Pereira, Bruno B Andrade
{"title":"Rethinking Basic Science Teaching in Medical Education: A Viewpoint on Its Past, Present, and Future.","authors":"Kátia M Avena, Ana Paula A Brito, Luiz F Quintanilha, Mariana Araújo-Pereira, Bruno B Andrade","doi":"10.2196/80646","DOIUrl":"10.2196/80646","url":null,"abstract":"<p><strong>Unlabelled: </strong>Basic sciences remain a cornerstone of medical education, but the terms of the debate about their importance have changed. The central risk is no longer their formal exclusion from medical curricula but their curricular invisibility: the gradual dilution of mechanistic reasoning within integrated, technology-mediated, and institutionally unequal training environments. In this Viewpoint, we revisit the past, present, and future of basic science teaching to argue that reform must protect conceptual progression, curricular visibility, and clinical transfer. Active learning, curricular integration, digital tools, and AI may strengthen scientific literacy, but only when they are anchored in faculty development, institutional support, and explicit commitments to rigor and equity.</p>","PeriodicalId":51757,"journal":{"name":"Interactive Journal of Medical Research","volume":"15 ","pages":"e80646"},"PeriodicalIF":3.3,"publicationDate":"2026-07-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13411432/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148610171","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Individual Research Behaviors and Research Funding Acquisition Across Fields and Career Periods: Regression Analysis.","authors":"Akiko Hashiguchi, Satoru Takahashi","doi":"10.2196/98428","DOIUrl":"10.2196/98428","url":null,"abstract":"<p><strong>Background: </strong>Acquiring external funding for academic research is a crucial element of researcher performance assessment. However, funding opportunities are often concentrated among a limited number of researchers, reinforcing existing structural inequalities. Under these conditions, it is important to clarify how individual researchers can improve their ability to secure external funding through their own actions and thereby build sustainable academic careers. In addition, fair faculty evaluation requires recognizing disciplinary differences in funding acquisition without assuming a normative research environment.</p><p><strong>Objective: </strong>This study aimed to examine whether research-related behaviors at different career stages contribute to variations in funding acquisition capability across research fields.</p><p><strong>Methods: </strong>We used funding data from Grant-in-Aid for Scientific Research, Japan's largest competitive research funding program, and classified 1152 professors according to their lifetime patterns of research funding acquisition. We also collected data on individual research-related behavioral characteristics, including supervisor prestige, authorship position, publication quality, collaborative research structure, and funding acquisition strategies, from publication records and administrative data, constructing a dataset of 804 researchers. By integrating these datasets, we conducted univariate and multivariate regression analyses to examine the factors associated with research funding acquisition.</p><p><strong>Results: </strong>Field-specific differences were observed in the upper range of funding levels and individual behaviors. High-funding recipients were found only in the field of basic and internal medicine. Univariate logistic regression analyses showed that early-career publication success (basic medicine: odds ratio [OR] 1.48, 95% CI 1.22-1.79; internal medicine: OR 1.34, 95% CI 1.06-1.69; and surgery: OR 1.70, 95% CI 1.28-2.27) and midcareer senior authorship were significantly associated with funding acquisition (basic medicine: OR 5.99, 95% CI 2.63-13.65; internal medicine: OR 3.17, 95% CI 1.16-8.70; and surgery: OR 9.79, 95% CI 3.26-29.43). In addition, supporting specific collaborators (surgery: OR 2.09, 95% CI 1.10-3.97) and the quality of publications during the first 12 years of a researcher's career were major determinants of success (surgery: OR 2.22, 95% CI 1.18-4.17). In multiple linear regression analyses with total funding as the outcome, the adjusted R² values were 0.576 for surgery, 0.890 for social medicine, and 0.738 for dentistry, indicating that the models accounted for many behavioral factors associated with funding acquisition. However, the model fit suggests that additional relevant factors may influence funding acquisition in basic medicine, internal medicine, and nursing.</p><p><strong>Conclusions: </strong>This study identified individual behaviors that infl","PeriodicalId":51757,"journal":{"name":"Interactive Journal of Medical Research","volume":"15 ","pages":"e98428"},"PeriodicalIF":3.3,"publicationDate":"2026-07-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13405367/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148610051","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Within-Provider Variation in Prices for Commonly Utilized Services in Office Setting: Cross-Sectional Study.","authors":"Yuvraj Pathak, David Muhlestein","doi":"10.2196/96883","DOIUrl":"10.2196/96883","url":null,"abstract":"<p><strong>Unlabelled: </strong>Our study uses the latest Transparency in Coverage data to show that there is wide variation in health care prices for some of the most commonly utilized services in the United States. The findings demonstrate that there is an opportunity for employers, policymakers, and other stakeholders to curb health care spending by choosing cost-efficient health care networks and providers.</p>","PeriodicalId":51757,"journal":{"name":"Interactive Journal of Medical Research","volume":"15 ","pages":"e96883"},"PeriodicalIF":3.3,"publicationDate":"2026-07-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13394878/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148580977","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Cardiac Resynchronization Therapy With Defibrillator Using the JROAD-DPC Database: Cost-Effectiveness Analysis.","authors":"Kazuki Ohashi, Masaya Watanabe, Yasuhiro Morii, Hisashi Yokoshiki, Kengo Kusano, Katsuhiko Imai, Masahiko Takagi, Teiichi Yamane, Hiroshi Tada, Katsuhiko Ogasawara","doi":"10.2196/94073","DOIUrl":"10.2196/94073","url":null,"abstract":"<p><strong>Background: </strong>Cardiac resynchronization therapy with defibrillator (CRT-D) improves survival, reduces hospitalization, and enhances quality of life in patients with heart failure and reduced ejection fraction (HFrEF). As heart failure prevalence increases in aging societies such as Japan, the associated clinical and economic burden continues to rise. Previous cost-effectiveness analyses conducted in multiple countries indicate that CRT-D may be cost-effective in selected patients with HFrEF. However, its cost-effectiveness within the Japanese health care system remains uncertain.</p><p><strong>Objective: </strong>This study aimed to evaluate the cost-effectiveness of CRT-D in patients with HFrEF within the Japanese health care setting.</p><p><strong>Methods: </strong>A partitioned survival model was developed with 3 health states: after treatment (follow-up), hospitalization, and death. Survival for CRT-D was estimated by reconstructing individual patient-level data from the Kaplan-Meier curve of the RAFT (Resynchronization-Defibrillation for Ambulatory Heart Failure Trial) study using the method proposed by Guyot et al followed by fitting multiple parametric models; the gamma distribution was selected for the base case analysis. Survival for optimal medical therapy (OMT), the comparator, was estimated by applying a hazard ratio from a published meta-analysis. Hospitalization rates and device longevity were derived from prior studies. Cost estimates were obtained from the JROAD-DPC (Japanese Registry Of All cardiac and vascular Disease-Diagnostic Procedure Combination) database and the Japanese medical fee schedule. Utility values were assigned according to New York Heart Association class assuming treatment-specific distributions. The analysis was conducted from the public health care payer perspective using a monthly cycle over a 20-year time horizon. Deterministic and probabilistic sensitivity analyses were performed. Additionally, scenario analyses were conducted by varying the duration of treatment effect.</p><p><strong>Results: </strong>In the base case analysis, per capita costs were ¥12,258,410 (¥1=US $0.006 as of July 7, 2026) for CRT-D and ¥640,056.90 for OMT, resulting in an incremental cost of ¥11,618,353. CRT-D generated 7.07 quality-adjusted life years (QALYs) compared with 4.75 QALYs for OMT, yielding an incremental gain of 2.32 QALYs. The incremental cost-effectiveness ratio (ICER) was ¥5,009,880 per QALY. Scenario analyses showed that, when treatment effect waned after 7.5 years, the ICER increased to ¥5,423,235 per QALY. When the time horizon was shortened to 10 years or extended to 30 years, the ICERs were ¥8,523,072 and ¥4,386,803 per QALY, respectively. Deterministic sensitivity analysis identified CRT-D efficacy (hazard ratio), discount rate, and initial treatment cost as primary ICER drivers. Probabilistic sensitivity analysis produced a median ICER of ¥5,022,618 (IQR ¥4,448,306-¥5,760,425) per QALY, with ","PeriodicalId":51757,"journal":{"name":"Interactive Journal of Medical Research","volume":"15 ","pages":"e94073"},"PeriodicalIF":3.3,"publicationDate":"2026-07-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13387419/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148551346","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Till Baldenius, Kathrin Jürchott, Christine Haeger, Susann Behrendt, Stefan Blüher, Susanne Schnitzer
{"title":"Health Care-Related Determinants of First-Time Long-Term Care Need in Older Adults in Germany: Retrospective Cohort Study Using Claims Data.","authors":"Till Baldenius, Kathrin Jürchott, Christine Haeger, Susann Behrendt, Stefan Blüher, Susanne Schnitzer","doi":"10.2196/86572","DOIUrl":"10.2196/86572","url":null,"abstract":"<p><strong>Background: </strong>In recent years, German long-term care (LTC) insurance has experienced an unprecedented increase in the number of beneficiaries. This raises the question of the role of health care in preventing or delaying the need for LTC. At present, related findings are limited. Addressing this research gap could promote longevity and improve quality of life while reducing the financial strain on the social security system.</p><p><strong>Objective: </strong>This study aimed to investigate the associations between the utilization of health care services and first-time LTC need.</p><p><strong>Methods: </strong>This retrospective cohort study examined nationwide linked claims data from the German statutory health and LTC insurance fund, AOK. The dataset included all individuals aged ≥60 years. Using multiple logistic regression, we investigated the association between health care utilization during the 5-year exposure period from 2016 to 2020 and the occurrence of first-time LTC need during the first quarter of 2021. Physician care, pharmaceutical care, physiotherapy, and medical aids were analyzed while adjusting for age, sex, regional variables, and comorbidities. Metrically scaled variables were categorized using the Fisher-Jenks algorithm to explore possible nonlinearities. Individuals who needed LTC prior to 2021 were excluded.</p><p><strong>Results: </strong>The study population comprised 5.3 million individuals. A total of 54.3% (n=2.9 million) were women, and the mean age was 71.3 (SD 8.16) years. Receiving more than 2 of the 5 recommended screenings and vaccinations examined, compared with receiving none, was associated with a strong reduction in the odds of first-time LTC need (odds ratio [OR] 0.62, 95% CI 0.60-0.64; P<.001). Odds of first-time LTC need were also significantly lower with high numbers of specialist groups and low numbers of specialist days (more than 7 specialist groups consulted and fewer than 48 billing days) compared with no specialist utilization (any specialist utilization: OR 0.82, 95% CI 0.79-0.85; P<.001; more than 7 instead of fewer than 5 specialist groups: OR 0.94, 95% CI 0.92-0.96; P<.001). Likewise, a physiotherapy prescription in between 5 and 10 quarters of the 5-year period instead of none was related to lower odds of first-time LTC need (OR 0.81, 95% CI 0.79-0.83; P<.001). Generalist care, hospitalizations, polypharmacy, and potentially inadequate medication were concomitant with first-time LTC need. Among the disease management programs and medical aids examined, there were both positive and negative relationships with first-time LTC need.</p><p><strong>Conclusions: </strong>Utilization of recommended screenings, vaccinations, specialist physician care, and physiotherapy is substantially and significantly associated with the nonoccurrence of first-time LTC need in the older German population. Our study provides a foundation for future research on orienting health care toward preventing f","PeriodicalId":51757,"journal":{"name":"Interactive Journal of Medical Research","volume":"15 ","pages":"e86572"},"PeriodicalIF":3.3,"publicationDate":"2026-07-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13384046/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148537772","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Angela Ym Leung, Karen Sl Cheung, Kai Ling Ou, Ivy Yan Zhao, Min Qiu, K M Wan, Jed Montayre, Yaqi Huang
{"title":"Enhancing Healthy Longevity: A Scoping Review of Practices and Interventions.","authors":"Angela Ym Leung, Karen Sl Cheung, Kai Ling Ou, Ivy Yan Zhao, Min Qiu, K M Wan, Jed Montayre, Yaqi Huang","doi":"10.2196/94085","DOIUrl":"https://doi.org/10.2196/94085","url":null,"abstract":"<p><strong>Background: </strong>Over the past two decades, concerns have arisen about the distinction between health span and lifespan, highlighting that longevity does not necessarily equate to good health, a concept often referred to as \"healthy longevity.\" While various strategies have been explored to promote healthy aging and achieve healthy longevity, it remains uncertain which practices are most effective.</p><p><strong>Objective: </strong>To identify the existing and emerging practices and interventions that promote healthy longevity, identify the key components of these practices and interventions, and to consider how stakeholders contribute to these practices and interventions.</p><p><strong>Methods: </strong>Design: A scoping review of literature Methods: Arksey & O'malley's six-stage framework was used to conduct and guide reporting. The Joanna Briggs Institute Population-Concept-Context framework was used to define eligibility criteria and select studies that report practices/interventions aimed at achieving long health span or promoting healthy longevity carried out in community. Data were manually extracted by two independent reviewers to detail the characteristics of these practices and interventions, guide the data charting process and narrative synthesis. Data Sources: Six databases (PubMed, Web of Science, Embase, Scopus, CINAHL, and Google Scholar) were searched for academic papers published between January 2010 and February 2025.</p><p><strong>Results: </strong>Twenty-one studies met the inclusion criteria. Studies, mostly published after 2020, were predominantly conducted in high income settings (81.0%) across North America, Europe, and Asia. Four study types were identified: interventional (33%), intervention development (19%), association (24%), and descriptive (24%). Interventional. Intervention development studies primarily described multi component programmes targeting individual and social determinants of health and generally reported beneficial effects on physical, cognitive, and psychosocial outcomes. Association studies linked micro , meso , and macro level factors (e.g. nutrition, household expenditure, housing quality, health insurance, public financing policy) to healthy longevity indicators. Descriptive studies highlighted themes cross micro and meso level, such as finance, physical activity, mental and spiritual health, digital literacy, independent living, safety, social support, and healthcare support.</p><p><strong>Conclusions: </strong>The identified community-based strategies, practices, and policies which extend health span represent the joint effort of multiple stakeholders and disciplines. The implementation of these practices and policies are worthy to be supported. More studies in diverse socioeconomic contexts are needed.</p><p><strong>Clinicaltrial: </strong></p>","PeriodicalId":51757,"journal":{"name":"Interactive Journal of Medical Research","volume":" ","pages":""},"PeriodicalIF":3.3,"publicationDate":"2026-07-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148474173","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mimi M Kim, Amin M Shanaa, Hossam Hammady, Mohammad Aboelnour, Robert Ayan
{"title":"Enhancing Transparency, Auditability, and Reproducibility of Deduplication in Systematic Reviews: Tutorial for the Rayyan Method and Systematic Auto Resolver.","authors":"Mimi M Kim, Amin M Shanaa, Hossam Hammady, Mohammad Aboelnour, Robert Ayan","doi":"10.2196/94317","DOIUrl":"10.2196/94317","url":null,"abstract":"<p><strong>Unlabelled: </strong>Deduplication across search results is one of the earliest and most critical steps in the systematic review methodological process; yet, existing solutions often lack the transparency, auditability, and reproducibility required by rigorous systematic review standards. Many automated deduplication tools introduce bias through opaque, nonconfigurable algorithmic decisions, while also potentially removing relevant references through false positive identification. We provide a tutorial on the Rayyan Method, including the Systematic Auto Resolver feature for the deduplication process. This method is defined by an enhanced deduplication approach that combines high-sensitivity duplicate detection with user-controlled resolution criteria. Systematic Auto Resolver enables research teams to define, apply, and document their own deduplication standards rather than relying on predetermined automated decisions. Users apply deduplication criteria, iteratively reviewing results after each pass, maintaining complete control over methodological decisions. The Rayyan Method addresses critical limitations in current deduplication approaches by supporting methodological rigor through user-controlled resolution while enhancing efficiency, transparency, and reproducibility. By empowering research teams to define their own deduplication criteria, this approach supports and aligns with the prescribed methodologically rigorous systematic review process. The method provides a citable framework for researchers to comprehensively document their deduplication methodology.</p>","PeriodicalId":51757,"journal":{"name":"Interactive Journal of Medical Research","volume":"15 ","pages":"e94317"},"PeriodicalIF":3.3,"publicationDate":"2026-07-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13367408/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148450363","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}