Interactive Journal of Medical Research最新文献

{"title":"Acupuncture and Moxibustion for Poststroke Depression: Systematic Review.","authors":"Lu Meng, Chuang-Long Xu, Xiao-Xu He, Xiao-Chan Tan","doi":"10.2196/76577","DOIUrl":"https://doi.org/10.2196/76577","url":null,"abstract":"<p><strong>Background: </strong>Poststroke depression (PSD) is a common complication following stroke. In recent years, several systematic reviews have evaluated the effects of moxibustion and acupuncture on PSD; however, their findings have been inconsistent.</p><p><strong>Objective: </strong>This overview of systematic reviews aimed to assess the methodological quality, reporting quality, and strength of evidence of existing systematic reviews on acupuncture and moxibustion for PSD. In addition, this study also analyzed the limitations of previous studies and suggested directions for future research.</p><p><strong>Methods: </strong>Systematic reviews concerning acupuncture and moxibustion for PSD published before August 10, 2024, were identified from 8 databases, including PubMed, Embase, Cochrane Library, Web of Science, China National Knowledge Infrastructure, Wanfang, VIP Database, and Chinese Biomedical Literature Database. Eligible studies included systematic reviews and meta-analyses of randomized controlled trials comparing moxibustion and acupuncture for the treatment of PSD. The methodological quality, reporting quality, and evidence quality were evaluated using AMSTAR 2 (Assessment of Multiple Systematic Reviews-2), PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) 2020, and GRADE (Grading of Recommendations Assessment, Development and Evaluation), respectively. The corrected covered area was calculated to assess overlap among the included primary studies.</p><p><strong>Results: </strong>A total of 24 studies were included. According to the Assessment of Multiple Systematic Reviews-2 assessment, all studies were rated as having \"low\" or \"critically low\" methodological quality. Based on PRISMA, 1 study demonstrated seriously inadequate reporting quality, while 21 studies had partially inadequate reporting quality. The quality of evidence in the included reviews ranged from very low to moderate. Most of the primary outcomes exhibited mild to moderate overlap among studies.</p><p><strong>Conclusions: </strong>Most of the included systematic reviews indicated that acupuncture may be beneficial for PSD. Nevertheless, the methodology, reporting, and evidence quality of these reviews require improvement. Stronger evidence will depend on the conduct of larger, multicenter, rigorously designed randomized controlled trials, as well as high-quality systematic reviews.</p>","PeriodicalId":51757,"journal":{"name":"Interactive Journal of Medical Research","volume":"14 ","pages":"e76577"},"PeriodicalIF":1.9,"publicationDate":"2025-10-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145310027","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Community Comfort With Automatic Sharing of Race, Ethnicity, and Language Data Between Health Care Settings: Cross-Sectional Study.","authors":"Noah Brazer, Baylah Tessier-Sherman, Deron Galusha, Sakinah C Suttiratana, Corrine Liu, Katherine K Kim, Mark E Abraham, Marcella Nunez-Smith, Karen H Wang","doi":"10.2196/67288","DOIUrl":"10.2196/67288","url":null,"abstract":"<p><strong>Background: </strong>Little is known regarding patient attitudes toward automatic sharing of race, ethnicity, and language (REL) data in health care settings despite the universal practice of data sharing across health care institutions and providers.</p><p><strong>Objective: </strong>This study aims to assess public comfort with disclosing and automatically sharing REL data in health care settings and understand the social factors associated with these attitudes.</p><p><strong>Methods: </strong>Using the 2022 DataHaven Community Wellbeing Survey from 1196 adult Connecticut residents, we examined factors associated with public comfort with disclosing and automatically sharing REL data across health care settings. We generated unadjusted and adjusted logistic models to examine associations between factors and responses to the data-sharing questions.</p><p><strong>Results: </strong>Most residents surveyed were White (n=873, 73%), followed by African American or Black (n=167, 14%), Asian or Native Hawaiian or other Pacific Islander (n=31, 2.6%), multiracial (n=31, 2.6%), and American Indian or Alaska Native (n=12, 1%). The majority of respondents were not Hispanic or Latino (n=1051, 87.9%). More than half of respondents reported excellent or very good self-rated health (SRH; n=635, 53.1%), and most participants reported almost always trusting their health care provider (n=939, 78.5%). Most participants reported being willing to share race and ethnicity data at a hospital or clinic (n=1008, 84.3%) and REL data automatically (n=947, 79.2%) in health care settings. Hispanic or Latino (adjusted odds ratio [AOR] 0.049, 95% CI 0.25-0.94) and multiracial (AOR 0.32, 95% CI 0.14-0.76) respondents were less likely to be willing to disclose race and ethnicity data compared to those who were not Hispanic or Latino and who were White, respectively. Individuals who sometimes trust health care providers (AOR 0.57, 95% CI 0.35-0.94) or rarely/never (AOR 0.35, 95% CI 0.15-0.85) were less likely to be willing to disclose race and ethnicity data than those who almost always trust health care providers. African American or Black (AOR 0.46, 95% CI 0.29-0.72) and American Indian or Alaska Native (AOR 0.18, 95% CI 0.04-0.75) individuals were less likely to be willing to share REL data automatically than White individuals. Those who sometimes trust health care providers (AOR 0.48, 95% CI 0.31-0.74) or rarely/never trust health care providers (AOR 0.25, 95% CI 0.11-0.56) were less likely to be willing to share REL data automatically than those who almost always trust health care providers. Those with poor/fair SRH versus very good/excellent SRH were less likely to be willing to share REL data automatically (AOR 0.54, 95% CI 0.34-0.85).</p><p><strong>Conclusions: </strong>Racial and ethnic identity, SRH, and trust in health care providers affect willingness to share REL information with providers and other health systems.</p>","PeriodicalId":51757,"journal":{"name":"Interactive Journal of Medical Research","volume":"14 ","pages":"e67288"},"PeriodicalIF":1.9,"publicationDate":"2025-10-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12500222/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145240359","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Understanding the Mental and Physical Burdens of Physicians and Identifying Support Interventions in Bangladesh: Qualitative Study.","authors":"Rahat Jahangir Rony, Shams Akbar Aalok, Lamia Amin Tisha, Marzan Mahatab, Nova Ahmed","doi":"10.2196/76934","DOIUrl":"10.2196/76934","url":null,"abstract":"&lt;p&gt;&lt;strong&gt;Background: &lt;/strong&gt;The COVID-19 pandemic had a substantial, negative impact on the world, and physicians played a crucial role in providing health care while facing the risk of contracting the virus themselves. While working on the frontlines, they also needed to protect themselves and their families from the virus. Unfortunately, their mental health was not given the attention it deserved. Many physicians experienced burnout due to the numerous challenges they faced, yet they received little support. Resource-limited countries such as Bangladesh were particularly affected due to a lack of resources. Although high-income countries have proposed a well-being model for physicians, this model is not directly applicable to resource-limited nations. However, redefining the model to suit the specific needs of physicians in resource-limited countries could provide sustainable support for their well-being.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Objective: &lt;/strong&gt;We aimed to gain a deeper understanding of the mental and physical burdens faced by Bangladeshi physicians during the COVID-19 pandemic, and the contextual factors influencing their well-being. By understanding these aspects, we can recommend an adaptable, effective, and sustainable contextual model.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Methods: &lt;/strong&gt;We conducted semistructured online interviews with 14 physicians in Chattogram, Bangladesh, during the COVID-19 pandemic. The physicians actively working in the COVID-19 unit were recruited from public and private hospitals through purposive sampling. Participants were aged between 25 and 35 years and had up to 8 years of working experience, including 43% (6/14) interns, 36% (5/14) medical officers, 14% (2/14) researchers, and 7% (1/14) surgeons. Each interview was conducted in Bengali, and we obtained consent to record the audio. Overall, 637 minutes of discussion were translated and transcribed. The results were analyzed using reflexive thematic analysis.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Results: &lt;/strong&gt;We identified factors that impacted physicians' mental and physical health and well-being during the COVID-19 pandemic. They frequently dealt with undiagnosed patients, which put them at risk. Physicians often feared the potential danger their profession posed to their families, choosing to prioritize their family's safety over their own. In addition, heavy workloads, excessive duty hours, and a shortage of colleagues substantially affected their sleep patterns and disrupted their regular work schedules. Instead of receiving societal support, they often faced negative perceptions from the public. In addition, during times of mass patient deaths, many physicians struggled to cope with their emotions without any mental health support.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Conclusions: &lt;/strong&gt;Our work shows physicians' mental and physical health burdens with various contextual difficulties. We understood these concerns and suggested a contextual (emphasizes understanding and addressing users' behavior within its specif","PeriodicalId":51757,"journal":{"name":"Interactive Journal of Medical Research","volume":"14 ","pages":"e76934"},"PeriodicalIF":1.9,"publicationDate":"2025-09-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12514411/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145151766","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Horizon Scanning Methods for Health Care Technology Innovation Identification: Rapid Scoping Review of Patent Research Studies.","authors":"Sonia Garcia Gonzalez-Moral, Erin Pennock, Olushola Ewedairo, Elizabeth Green, James Elgey, Andrew Mkwashi","doi":"10.2196/70323","DOIUrl":"10.2196/70323","url":null,"abstract":"&lt;p&gt;&lt;strong&gt;Background: &lt;/strong&gt;Patents are an early sign of innovation, yet their role in horizon scanning for health care remains unclear.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Objective: &lt;/strong&gt;This study investigates the role of, and methods for, patent analysis in advancing health care technology innovation in a sector that is characterized by diverse health care technologies and significant research investment. Patents are critical early indicators of innovation, supporting horizon scanning and weak signal detection. The study aimed to identify intellectual property sources, evaluate methods for patent retrieval and analysis, and outline objectives for using patent data to anticipate trends and inform health care strategies.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Methods: &lt;/strong&gt;A rapid scoping review was conducted following Cochrane Rapid Review Methods recommendations and PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) guidelines, with a preregistered protocol on the Open Science Framework. Searches in Embase, IEEE Xplore, and Web of Science targeted records published 2020 onward to capture the most recent sources, methods, and tools. Three independent reviewers screened studies using Rayyan (Qatar Computing Research Institute). We included any study type published since 2020 that provided patent sources data, methods, and tools applied to the study of health care technologies. Our data extraction included bibliographic details, study characteristics, and methodological information. Risk of bias assessments were not undertaken. Narrative and tabular methods, supplemented by visual charts, were used to synthesize findings.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Results: &lt;/strong&gt;Our searches identified 1741 studies, of which 124 were included after title, abstract, and full-text screening, with 54% being original research, 43.5% reviews, and the remainder being conference abstracts (2.5%). Most studies (68%) relied solely on patent databases, while others searched the gray and published literature. Research objectives of the included studies were grouped into 10 themes, with trend analysis (50%) and the provision of recommendations for future research, policy, and strategy development (20%) being the most common. Our review identified up to 47 patent databases, with 27% of studies using multiple sources. Whenever time limits were reported, the mean time horizon for patent searches was 24.6 years, ranging from 1900 to 2019. Automated approaches, used in 33% (n=43) of studies, frequently used tools such as Gephi (Gephi Consortium) for network visualization. Disease mapping based on National Institute for Health and Care Excellence classification indicated that cancer (19%) and respiratory conditions (16%), particularly COVID-19, were key areas.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Conclusions: &lt;/strong&gt;Patent data are valuable for identifying technological trends and informing policy and research strategies. While patents provide crucial insights into emerging technologies, inconsistent deduplication prac","PeriodicalId":51757,"journal":{"name":"Interactive Journal of Medical Research","volume":"14 ","pages":"e70323"},"PeriodicalIF":1.9,"publicationDate":"2025-09-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12425427/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145042155","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Shifting Focus: Evaluating the Safety and Efficacy of a Non-Weight-Centric Approach to Obesity Prevention in Rural and Urban Female Adolescents: A Quasi-Experimental Study.","authors":"Areeg Zuair, Rola Jalloun, Naif Alzahrani, Fahad Alhowaymel, Esraa Merza, Bandar Alhumaidi, Mohammad Alahmadi","doi":"10.2196/71341","DOIUrl":"https://doi.org/10.2196/71341","url":null,"abstract":"&lt;p&gt;&lt;strong&gt;Background: &lt;/strong&gt;Obesity is increasing among Saudi adolescents, with rural females disproportionately underserved due to limited health education, sociocultural barriers, and scarce resources. While most school programs emphasize weight, global recommendations call for non-weight-centric approaches to avoid stigma. The Green Apple program is a school-based, weight-neutral intervention focusing on energy metabolism, nutrient balance, and dietary sources. Its enhanced version adds a unit on metabolic non-communicable disease (MNCD) prevention, grounded in the health belief model. Although previously tested in urban settings, it has not yet been evaluated among rural female students.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Objective: &lt;/strong&gt;This study aimed to examine the effectiveness of the Green Apple educational intervention in improving knowledge about MNCDs, while also assessing its safety, defined as the absence of adverse psychological (body image discrepancy, disordered eating symptoms) and behavioral (increased sedentary behavior) outcomes.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Methods: &lt;/strong&gt;This quasi-experimental study included 105 participants from urban and rural female schools in Saudi Arabia. Two classes within each school were assigned to one of two program versions: (1) enhanced intervention (Green Apple + MNCD): a three-unit, non-weight-centric educational program that included content on the prevention of MNCDs. (2) intervention (Green Apple only): a two-unit, non-weight-centric educational program without MNCD content. The intervention was delivered once per week over two consecutive weeks (two sessions), while the enhanced intervention included an additional third session. Linear mixed-effects models assessed intervention effects across three time points: baseline, post-intervention, and one-month follow-up.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Results: &lt;/strong&gt;The mean age across participants was 16.42 years (SD = 0.66), with a significant difference between groups: 15.97 years (SD = 0.41) in the enhanced intervention group and 17.00 years (SD = 0.42) in the intervention group (P &lt; .001). Both interventions significantly improved knowledge across schools. The enhanced intervention (Green Apple + MNCD) group demonstrated an increase of 1.65 (95% CI [0.61, 2.70], P &lt; .001) from baseline to follow-up, while the intervention (Green Apple) group showed an increase of 1.26 (95% CI [0.10, 2.43], P = .02). However, no significant between-group differences were observed at baseline (mean difference = 0.20, P = .65), post-intervention (mean difference = 0.79, P = .08), or follow-up (mean difference = 0.73, P = .13). Although sedentary behavior did not significantly decrease across all schools, a significant reduction was observed in rural schools receiving the Green Apple intervention (-3.12, 95% CI [-5.67, -0.56], P = .02).&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Conclusions: &lt;/strong&gt;The Green Apple program shows promise as a culturally tailored, weight-neutral intervention to enhance metabolic health literacy","PeriodicalId":51757,"journal":{"name":"Interactive Journal of Medical Research","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2025-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145031154","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Dengue Epidemiology in 7 Southeast Asian Countries: 24-Year, Retrospective, Multicountry Ecological Study.","authors":"Shun-Long Weng, Fang-Yu Hung, Sung-Tse Li, Bo-Huang Liou, Chun-Yan Yeung, Yu-Lin Tai, Yi-Hsuan Wu, Ya-Ning Huang, Nan-Chang Chiu, Liang-Yen Lin, Hsin Chi, Chien-Yu Lin","doi":"10.2196/70491","DOIUrl":"10.2196/70491","url":null,"abstract":"<p><strong>Background: </strong>Dengue fever remains the most significant vector-borne disease in Southeast Asia, imposing a substantial burden on public health systems. Global warming and increased international mobility may exacerbate the disease's prevalence. Furthermore, the unprecedented COVID-19 pandemic may have influenced the epidemiological patterns of dengue.</p><p><strong>Objective: </strong>This study aimed to evaluate epidemiological changes in dengue incidence in Southeast Asia.</p><p><strong>Methods: </strong>We conducted a retrospective, multicountry ecological study analyzing trends in dengue incidence in 7 Southeast Asian countries from January 2000 to December 2023. Data were extracted from official World Health Organization reports and national health department databases. Countries with data that were incomplete, inconsistent, or not publicly available were excluded from the final analysis. Annual incidence rates were analyzed, and linear trends were calculated to assess long-term patterns.</p><p><strong>Results: </strong>Epidemiological data from 7 Southeast Asian countries, comprising Thailand, Singapore, Vietnam, Malaysia, the Philippines, Cambodia, and Taiwan, were analyzed across the 24-year study period. A notable nadir in dengue cases was observed coinciding with the COVID-19 pandemic. Significant increasing trends in dengue incidence were identified in Singapore, Vietnam, Malaysia, and the Philippines (slopes: 8.243, 6.513, 8.737, and 8.172; R2 values: 0.14, 0.34, 0.345, and 0.46, respectively, all P<.05).</p><p><strong>Conclusions: </strong>Dengue fever continues to pose a significant public health challenge in Southeast Asia. Our analysis demonstrates a substantial increase in dengue cases in several countries over the study period. While a temporary decline was observed during the COVID-19 pandemic, a subsequent resurgence of cases highlights the persistent threat of dengue in the region. These findings underscore the critical need for sustained surveillance and innovative control strategies to mitigate the impact of dengue in Southeast Asia.</p>","PeriodicalId":51757,"journal":{"name":"Interactive Journal of Medical Research","volume":"14 ","pages":"e70491"},"PeriodicalIF":1.9,"publicationDate":"2025-09-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12416874/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145024718","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Mapping Hot Spots and Global Research Trends in Exergaming Between 1997 and 2024: Bibliometric Analysis.","authors":"Abdullah Kayhan, Elif Kose, Burcu Kayhan, Nan Zeng","doi":"10.2196/66738","DOIUrl":"10.2196/66738","url":null,"abstract":"&lt;p&gt;&lt;strong&gt;Background: &lt;/strong&gt;Exergaming, the combination of exercise and gaming, has emerged as an important area in physical activity (PA) research. By leveraging advances in video game technology, exergaming supports both physical and mental health. This growing interest in exergaming has increasingly attracted researchers over the years. Examining the development of exergaming research with a bibliometric approach is thought to offer valuable perspectives to researchers by revealing the trends and main contributions in the field.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Objective: &lt;/strong&gt;This study aims to identify the most researched concepts and topics in the field of exergaming; track the changes of trending topics over the years; identify the most influential journals as well as the authors who have contributed the most to the field; identify groundbreaking studies and neglected topics that shape future work; and reveal the countries, institutions, and collaborations that have contributed the most to the field. It also aims to identify research gaps in the field of exergaming and provide important recommendations for future research.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Methods: &lt;/strong&gt;A bibliometric analysis covering studies between 1997 and 2024 was conducted using the Web of Science database. The R-based Bibliometrix package and the Biblioshiny web interface were used for data analysis and visualization. The analysis included original research papers and reviews. These analyses provided insights into research trends, citation metrics, and thematic developments.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Results: &lt;/strong&gt;A total of 1626 studies were analyzed, and the results indicated a steep rise in exergaming research since 2015, peaking in the years 2020-2021. Major high-impact journals publishing in this area include Games for Health Journal and International Journal of Environmental Research and Public Health. Researchers who have contributed significantly and enriched the knowledge base of the exergaming field included Gao Zan, Eling de Bruin, and Zeng Nan. The most cited studies were classified into 2 different clusters, namely, cluster 1 that focuses on the concepts of PA, exercise, energy expenditure, and children, while cluster 2 focuses on rehabilitation, balance, adults, and aging. Medicine, information technology, and intention are some of the emerging themes. From a research productivity perspective, there is an undisputed front-runner, the United States, but substantial contributions have definitely come from either the Swiss Federal Institute of Technology or the Karolinska Institute.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Conclusions: &lt;/strong&gt;Despite significant growth in exergaming research over the last decade, research gaps remain, particularly in understanding how exergaming can be effectively integrated into long-term PA promotion and broader health outcomes. These gaps were identified by the absence or low representation of relevant keywords (eg, \"cost-effectiveness,\" \"community-based intervention,\" and \"lon","PeriodicalId":51757,"journal":{"name":"Interactive Journal of Medical Research","volume":"14 ","pages":"e66738"},"PeriodicalIF":1.9,"publicationDate":"2025-08-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12377698/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144978137","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"eHealth Literacy Interventions: Scoping Review.","authors":"Yan Wang, Yutian Niu, Rongjing Xu, Qingqing Zhang, Shoumei Jia, Anni Wang","doi":"10.2196/69640","DOIUrl":"10.2196/69640","url":null,"abstract":"<p><strong>Background: </strong>Electronic resources have become a predominant modality for health information dissemination in recent years. eHealth literacy (eHL) means individuals' competencies to effectively acquire and use health information from electronic sources. Enhancing eHL is thus essential to facilitate individuals' effective engagement with electronic resources and promote improved health management.</p><p><strong>Objective: </strong>This scoping review aimed to synthesize the characteristics of eHL interventions, thereby providing a reference for future intervention strategies.</p><p><strong>Methods: </strong>A comprehensive search of PubMed, Embase, Cochrane Library, Web of Science, ProQuest, CINAHL, CNKI, VIP, Wan Fang Data, and Sino Med limited to Chinese and English-language studies published before August 2024 was conducted. The interventional studies included had the explicit primary objective of enhancing eHL. We also incorporated studies that assessed eHL as a secondary outcome or mediator influencing health behaviors or clinical outcomes. All publications were required to provide publicly accessible complete datasets. We excluded conference abstracts and protocols. Academic theses and dissertations were included if they underwent institutional quality assurance through rigorous academic review processes and met predefined eligibility criteria.</p><p><strong>Results: </strong>A total of 35 studies were included in this review. The most prevalent eHL interventions (12/35, 34%) were delivered via mobile apps and devices in various settings, including educational institutions, public spaces, health care facilities, and community centers. These interventions predominantly focused on enhancing information literacy, health literacy, and computer literacy across the 6 domains of eHL: traditional, health, information, scientific, media, and computer literacy. A majority of the interventions were conducted on a weekly basis (6/13, 46%) and had a duration of 24 weeks (6/35, 17%). However, 77% (27/35) of interventions did not assess long-term effects. The primary outcomes of eHL interventions encompassed perceived eHL, actual eHealth knowledge and skills, health literacy, health behavior, and clinical outcomes, with 86% (30/35) indicating positive effects. The eHealth Literacy Scale was the most frequently used assessment tool.</p><p><strong>Conclusions: </strong>This study synthesizes the characteristics of eHL interventions. Current eHL interventions exhibit limitations in theoretical grounding, longitudinal tracking, and traditional or media literacy components. Overreliance on self-reported metrics constrains validity assessment. Future work should strengthen theoretical frameworks, integrate objective metrics, and enhance longitudinal designs.</p>","PeriodicalId":51757,"journal":{"name":"Interactive Journal of Medical Research","volume":"14 ","pages":"e69640"},"PeriodicalIF":1.9,"publicationDate":"2025-08-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12373412/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144978113","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Safety and Efficacy of Aspirin and Indobufen in the Treatment of Atherosclerotic Diseases: Systematic Review and Meta-Analysis.","authors":"Wenhao Pan, Linger Guan, Haicheng Zhang","doi":"10.2196/75363","DOIUrl":"10.2196/75363","url":null,"abstract":"<p><strong>Background: </strong>The pathogenesis of atherosclerotic thrombosis primarily involves platelet activation and aggregation, making antiplatelet therapy the cornerstone of treatment for such diseases.</p><p><strong>Objective: </strong>This meta-analysis aimed to compare the safety and efficacy of aspirin and indobufen in antiplatelet therapy for patients with atherosclerotic diseases.</p><p><strong>Methods: </strong>We searched the Cochrane Library, PubMed, Embase, Web of Science, and the Chinese Wanfang databases. The literature was screened according to predefined inclusion and exclusion criteria. Risk ratio (RR) was used to assess the magnitude of risk associated with exposure and our inclusion criteria are as follows: (1) the study population comprised adults (aged 18 years and older) with coronary heart disease caused by coronary artery atherosclerosis or stroke caused by intracranial atherosclerosis; (2) the intervention was represented by indobufen in the study groups versus aspirin in the control groups; (3) the primary outcome was the incidence of major adverse cardiovascular and cerebrovascular events or any bleeding or Bleeding Academic Research Consortium 2/3/5 bleeding; (4) the secondary outcomes were cardiovascular death, myocardial infarction, and ischemic stroke; adverse cardiovascular events such as coronary thrombus reformation, heart failure, myocardial infarction, stroke, angina pectoris, and cardiovascular death; stroke; myocardial infarction; and cardiovascular death; and (5) the studies were randomized clinical trials with either crossover or parallel designs or prospective observational trials.</p><p><strong>Results: </strong>Eighteen trials with a total of 12,981 patients were included in this study. Compared to aspirin, indobufen reduced the risk of (1) bleeding events (RR 0.54, 95% CI 0.41-0.71; P<.0001), (2) Bleeding Academic Research Consortium 2/3/5 bleeding (RR 0.50, 95% CI 0.26-0.94; P=.03), (3) adverse cardiovascular events (RR 0.43, 95% CI 0.30-0.61; P<.00001), and (4) myocardial infarction (RR 0.60, 95% CI 0.41-0.89; P=.01). However, there were no significant differences between the 2 groups in terms of major adverse cardiovascular and cerebrovascular events, stroke, or cardiovascular mortality.</p><p><strong>Conclusions: </strong>Compared with aspirin, indobufen demonstrated better safety and was not inferior to aspirin in terms of efficacy, with superior results in some aspects (eg, fewer risks of adverse cardiovascular events and myocardial infarction). Further studies with larger sample sizes or longer follow-up periods may provide additional evidence.</p>","PeriodicalId":51757,"journal":{"name":"Interactive Journal of Medical Research","volume":"14 ","pages":"e75363"},"PeriodicalIF":1.9,"publicationDate":"2025-08-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12391900/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144978081","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Developing Requirements for a Standardized System to Return Individual Research Results Back to Study Participants: Narrative Review.","authors":"Rosalyn Leigh Carr, Vita Chan, Nicholas C West, Matthias Görges","doi":"10.2196/65606","DOIUrl":"10.2196/65606","url":null,"abstract":"&lt;p&gt;&lt;strong&gt;Background: &lt;/strong&gt;The increasing prevalence of smart devices has created vast amounts of untapped data, presenting new opportunities for data sharing across various fields, such as environmental sciences, health management, and astrophysics. While a significant portion of the public is willing to donate personal data, we need to better understand how to obtain information about which data assets a person may hold and the risks, benefits, and potential uses of this data exchange mechanism. Developing a trusted data-sharing platform may increase participants' willingness to donate data and researchers' ability to return personalized results from research findings.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Objective: &lt;/strong&gt;This study aimed to develop a preliminary list of core requirements, which can be used to develop design recommendations for standardizing the return of individual research results to study participants across research disciplines.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Methods: &lt;/strong&gt;We conducted a narrative literature review of existing platforms used to return research results to study participants. The search strategy included English-language articles published between May 2013 and May 2023. Concepts related to returning, disseminating, and sharing research results were searched for in (1) published research reports on Web of Science and MEDLINE, (2) gray literature, and (3) the bibliographies of included articles. Screening and data extraction were performed by 2 independent reviewers using Covidence. Inclusion criteria required that the study (1) included human participants, (2) returned information based on data collected from or by participants, (3) was published in English, and (4) included a description of a results-sharing system. Articles that met all 4 inclusion criteria were included in the review; articles that met the first 3 were also presented as supplementary articles. Results and requirements were synthesized thematically.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Results: &lt;/strong&gt;Overall, 6608 abstracts were screened, and 266 articles underwent full-text review to identify 8 articles describing the development and evaluation of 7 different return of results systems. In total, 7 of the 8 articles reported the use of multimodal dissemination methods, including a combination of physical documents, emails, phone calls, and digital platforms to support text and graphical data representations. One article outlined accessibility features to serve the specific participant population. None of the articles described in detail how results were or were not anonymized. A total of 4 studies relied on an expert or clinician to share results on behalf of the research team. Additional educational or contextual materials were included alongside results in four studies, including specific materials designed for follow-up with experts and clinicians. Participants were not hesitant to receive unfavorable results and instead aimed to incorporate such information into their lives via lifest","PeriodicalId":51757,"journal":{"name":"Interactive Journal of Medical Research","volume":"14 ","pages":"e65606"},"PeriodicalIF":1.9,"publicationDate":"2025-08-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12387377/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144978027","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}