Lara N. Roberts, Michael Bryan, J. Daru, Beverley J. Hunt, Sajida Kazi, Will Lester, Bethan Myers, Sue Pavord, Mari Thomas, Clare Tower, Gillian Swallow
{"title":"Interest and barriers to research in obstetric haematology – findings from a national survey in the United Kingdom","authors":"Lara N. Roberts, Michael Bryan, J. Daru, Beverley J. Hunt, Sajida Kazi, Will Lester, Bethan Myers, Sue Pavord, Mari Thomas, Clare Tower, Gillian Swallow","doi":"10.1177/1753495x231219296","DOIUrl":"https://doi.org/10.1177/1753495x231219296","url":null,"abstract":"In 2021, the steering committee members of British Society of Haematology Obstetric Haematology Special Interest Group noted difficulties in opening research studies. This led to the development of a survey to further evaluate this issue. An electronic survey was distributed to all members of the British Society of Haematology Obstetric Haematology Special Interest Group and to relevant specialty leads of the National Institute for Health and Care Research Clinical Research Network for further dissemination within these networks. Responses were received from 65 participants (73% consultant grade); mainly haematologists (52%) or obstetricians (39%). Less than a third of participants reported dedicated time for research in their job plan, with only five participants reporting no challenges in opening research studies in obstetric haematology. The survey confirmed significant interest in obstetric haematology research, with barriers to participation. We propose further actions to facilitate increased research.","PeriodicalId":51717,"journal":{"name":"Obstetric Medicine","volume":"47 20","pages":""},"PeriodicalIF":0.7,"publicationDate":"2023-12-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138949442","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Joseph O’Sullivan, Hifsa Mahmood, Ruth A Curry, Charlotte J Frise
{"title":"Pregnancy in a woman with extreme short stature and low body weight secondary to a collagen VI-related muscular dystrophy","authors":"Joseph O’Sullivan, Hifsa Mahmood, Ruth A Curry, Charlotte J Frise","doi":"10.1177/1753495x231219298","DOIUrl":"https://doi.org/10.1177/1753495x231219298","url":null,"abstract":"Pregnancy poses significant physiological demands, and women of extreme short stature may be particularly at risk of complications. Described here are two pregnancies in a woman who was 130 cm tall with a body mass index of 12 kg/m2 and the maternal and neonatal outcomes. The challenges encountered in the care of our patient included cardiorespiratory compromise, management of medication dosing, management of delivery and bleeding risk.","PeriodicalId":51717,"journal":{"name":"Obstetric Medicine","volume":"32 22","pages":""},"PeriodicalIF":0.7,"publicationDate":"2023-12-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138949027","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Editorial: Meetings, education and collaboration","authors":"S. E. Lapinsky, J. Gehlert, Charlotte J Frise","doi":"10.1177/1753495x231216514","DOIUrl":"https://doi.org/10.1177/1753495x231216514","url":null,"abstract":"","PeriodicalId":51717,"journal":{"name":"Obstetric Medicine","volume":"55 1","pages":"209 - 210"},"PeriodicalIF":0.7,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138623430","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
J. Jindal, D. Launer, Georgia Richards, Francesco Dernie, Alice Dempsey, Sarah Carter, Sarah Loveridge, Sheba Jarvis, Idoia Elorza Ridaura, Lisa Reid, Lee Gethings, Elizabeth Want, Catherine Nelson Piercy, Hayley Martin, Kate Bramham, Kate Wiles, Elizabeth Ralston, Katherine R. Clark, Francois Dos Santos, S. Walji, J. Cegla, Alessia David, Lucy Barton, Catherine Nelson-Piercy
{"title":"Proceedings from the 43rd MacDonald Obstetric Medicine Society Meeting2.11.23","authors":"J. Jindal, D. Launer, Georgia Richards, Francesco Dernie, Alice Dempsey, Sarah Carter, Sarah Loveridge, Sheba Jarvis, Idoia Elorza Ridaura, Lisa Reid, Lee Gethings, Elizabeth Want, Catherine Nelson Piercy, Hayley Martin, Kate Bramham, Kate Wiles, Elizabeth Ralston, Katherine R. Clark, Francois Dos Santos, S. Walji, J. Cegla, Alessia David, Lucy Barton, Catherine Nelson-Piercy","doi":"10.1177/1753495X231212990","DOIUrl":"https://doi.org/10.1177/1753495X231212990","url":null,"abstract":"Background: Coroners in England and Wales publish Prevention of Future Death (PFD) reports when they believe action should be taken to prevent similar deaths from occurring, and organisations have a duty to respond within 56 days. These reports are publicly available, but under-utilised and poorly disseminated. Methods: We used an established and reproducible web-scraping and case-screening method using openly available code to screen 4411 PFDs from 1st July 2013 (inception) - 1st June 2023 for maternal deaths. We extracted demographic information, coroner ’ s concerns, and organisational responses, and employed directed content analysis to identify common themes. Results: We identi fi ed 29 PFDs concerning maternal deaths. The mean age of death was 34 years and 76% occurred in hospital. The most common causes of death were suicides and consequences of thromboembolism (6 cases each). The most frequent risk factor identi fi ed was extremes of age (<17 years or >35 years). Death most commonly occurred during the antepartum period. Coroners frequently voiced concerns around poor multidisciplinary working (59% of PFDs), failure to provide appropriate treatment (48%) and failure of timely escalation (38%). Only 38% of PFDs received a response from the organisation to which they were sent. When organisations did respond, 85% of responses implemented new changes including publishing new local policies, increasing multidisciplinary training in obstetric scenarios, or committing to increasing staf fi ng levels. Conclusions: PFDs can highlight gaps in obstetric care which, if appropriately addressed, could prevent future maternal deaths. However, the low response rate to reports suggest lessons are not being learnt","PeriodicalId":51717,"journal":{"name":"Obstetric Medicine","volume":" 44","pages":"3 - 14"},"PeriodicalIF":0.7,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138620938","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Hypokalaemia in pregnancy – Prevalence, underlying causes, and an approach to investigation","authors":"Jinwen He, A. Morton","doi":"10.1177/1753495x231213537","DOIUrl":"https://doi.org/10.1177/1753495x231213537","url":null,"abstract":"To investigate the prevalence and aetiology of hypokalaemia in pregnancy. This was a five-year retrospective audit of women who received care at a tertiary hospital, who developed hypokalaemia during pregnancy and within three weeks postpartum. Serum potassium and magnesium levels cause(s) of hospitalization and investigations for hypokalaemia were obtained from hospital records. One hundred and ten women developed hypokalaemia during pregnancy and the immediate postpartum period, representing 0.36% of total births. Ninety-one per cent of patients had mild to moderate hypokalaemia (K 2.6–3.1 mmol/L), while 9% had severe hypokalaemia (K < 2.6 mmol/L). The most common associations of hypokalaemia were infection (38%), vomiting (18%), hypertensive disorders (12%) and postpartum haemorrhage (9%). Twenty-four patients did not have a clear underlying aetiology of hypokalaemia, but only five had further investigations. There was inadequate investigation and follow-up of hypokalaemia, particularly in women in whom an obvious cause was not apparent.","PeriodicalId":51717,"journal":{"name":"Obstetric Medicine","volume":"26 1","pages":""},"PeriodicalIF":0.7,"publicationDate":"2023-11-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139212726","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Kristine Barnden, Katrina Moss, Heike Roth, Amanda Henry, SE Caroline, N. D. Alwis, Sally Beard, Natalie K Binder, N. Pritchard, Tu ’ uhevaha, J. K. ’. u-Lino, Sue P Walker, Owen Stock, Katie Groom, Scott Petersen, Joanne M Said, Sean Seeho, Stefan C Kane, Stephen Tong, L. Hui, N. Hannan, Helen McDougall, Nadia Olivier, Grace Yuan, Mark Tacey, David Langsford, B. Fato, Adrian J. Hobbs, K. Bubb, Yamema Esber, M. Gow, Lynne M Roberts, Sathia Sushil, Gregory K. Davis, Mark A Brown, G. Mangos, F. Pettit, Tony O ’ Sullivan, Shuyao Yan, Donna Lohmeyer, Angela Makris, Kelly Thompson, Jessica Han, Anna Krelle, C. McCormick, P. C. D. Crespigny, Julia Unterscheider, Jie Shang, Katie Harris, Maree Hackett, Mark Woodward, Aurora Upitis, Daniella Susic, Maria E Craig, Jonathan Sen, Jordan Dixon, Emma Smith, Sam Banks, Ashleigh-Georgia Sherriff, L. Lynch, Leah Wright, M. Oreto, Tom Marwick, E. Aldridge, M. Pathirana, M. Wittwer, Susan Sierp, S. Leemaqz, Claire T. Roberts, Gustaaf A. Dekker, Margaret A. Arstall
{"title":"SOMANZ abstract packet","authors":"Kristine Barnden, Katrina Moss, Heike Roth, Amanda Henry, SE Caroline, N. D. Alwis, Sally Beard, Natalie K Binder, N. Pritchard, Tu ’ uhevaha, J. K. ’. u-Lino, Sue P Walker, Owen Stock, Katie Groom, Scott Petersen, Joanne M Said, Sean Seeho, Stefan C Kane, Stephen Tong, L. Hui, N. Hannan, Helen McDougall, Nadia Olivier, Grace Yuan, Mark Tacey, David Langsford, B. Fato, Adrian J. Hobbs, K. Bubb, Yamema Esber, M. Gow, Lynne M Roberts, Sathia Sushil, Gregory K. Davis, Mark A Brown, G. Mangos, F. Pettit, Tony O ’ Sullivan, Shuyao Yan, Donna Lohmeyer, Angela Makris, Kelly Thompson, Jessica Han, Anna Krelle, C. McCormick, P. C. D. Crespigny, Julia Unterscheider, Jie Shang, Katie Harris, Maree Hackett, Mark Woodward, Aurora Upitis, Daniella Susic, Maria E Craig, Jonathan Sen, Jordan Dixon, Emma Smith, Sam Banks, Ashleigh-Georgia Sherriff, L. Lynch, Leah Wright, M. Oreto, Tom Marwick, E. Aldridge, M. Pathirana, M. Wittwer, Susan Sierp, S. Leemaqz, Claire T. Roberts, Gustaaf A. Dekker, Margaret A. Arstall","doi":"10.1177/1753495X231199817","DOIUrl":"https://doi.org/10.1177/1753495X231199817","url":null,"abstract":"The Lancet described climate change as the greatest global health threat of the twenty-fi rst century. This talk will focus on the effects of heat and poor air quality on pregnancy outcomes, and strategies to minimise harm. Climate change magni fi es existing inequalities","PeriodicalId":51717,"journal":{"name":"Obstetric Medicine","volume":"77 1","pages":"3 - 41"},"PeriodicalIF":0.7,"publicationDate":"2023-11-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139244251","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Gokcen Unal Kocabas, Ilgın Yıldırım Şimşir, Banu Sarer Yurekli, Asli Suner Karakulah, Burak Durmaz, Esma Pehlivan Koroglu, S. Yeral, Busra Ozcan, Ali Akdemir
{"title":"The association of plasma pancreastatin levels with insulin resistance in patients with gestational diabetes mellitus","authors":"Gokcen Unal Kocabas, Ilgın Yıldırım Şimşir, Banu Sarer Yurekli, Asli Suner Karakulah, Burak Durmaz, Esma Pehlivan Koroglu, S. Yeral, Busra Ozcan, Ali Akdemir","doi":"10.1177/1753495x231216032","DOIUrl":"https://doi.org/10.1177/1753495x231216032","url":null,"abstract":"Gestational diabetes mellitus (GDM) occurs on the background of increased insulin resistance. We aimed to investigate the levels of plasma pancreastatin (PST) levels and its association with metabolic, demographic, and anthropometric parameters in gestational diabetic and normal glucose-tolerant pregnant women. A total of 165 pregnant women in the 24th–28th week of pregnancy were enrolled in this cross-sectional study. PST levels were measured using ELISA method. Median PST levels were similar between GDM (n = 62, 37.6%) and normal glucose-tolerant control group (n = 103, 62.4%). In the GDM group, PST level showed a significant positive correlation with fasting insulin and the homeostasis model assessment of insulin resistance (HOMA-IR). In binary logistic regression analysis, PST levels did not predict the presence of GDM significantly. Positive correlation of PST with fasting insulin and HOMA-IR suggests that PST could be associated with insulin resistance. Further studies are needed as regards to the role of PST in GDM pathogenesis.","PeriodicalId":51717,"journal":{"name":"Obstetric Medicine","volume":"110 1","pages":""},"PeriodicalIF":0.7,"publicationDate":"2023-11-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139260736","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jia Jennifer Ding, S. Mitta, Martha B. Kole-White, Julie Roth, I. Malhamé
{"title":"Preventability of stroke during pregnancy and postpartum","authors":"Jia Jennifer Ding, S. Mitta, Martha B. Kole-White, Julie Roth, I. Malhamé","doi":"10.1177/1753495x231213437","DOIUrl":"https://doi.org/10.1177/1753495x231213437","url":null,"abstract":"The preventability of strokes during pregnancy and postpartum is understudied. We identified patients with ischemic and hemorrhagic strokes in pregnancy or within 12 weeks postpartum between 2009 and 2020 at an obstetric teaching hospital. We described the clinical course of the included cases. A multi-disciplinary panel adjudicated each occurrence of stroke according to a modified classification system for preventability. Fifteen patients experienced a stroke during pregnancy or postpartum. Precisely, 60% presented with a headache, and 47% of events were complicated by severe obstetrical hypertension. Two cases were thought to be “possibly preventable” due to delays in presentation to care and miscommunication regarding hypertension management goals. In a cohort of pregnant and postpartum patients with stroke at a tertiary-care center, strokes may be prevented by future initiatives focusing on patient and provider education regarding early warning signs of pregnancy-associated stroke and hypertension thresholds and management specific to pregnancy.","PeriodicalId":51717,"journal":{"name":"Obstetric Medicine","volume":"5 12","pages":""},"PeriodicalIF":0.7,"publicationDate":"2023-11-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139262927","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Generalized lichen amyloidosis in a pregnant woman: Coincidence or association","authors":"Phyo Zaw Aung, T. Nararatwanchai","doi":"10.1177/1753495x231214820","DOIUrl":"https://doi.org/10.1177/1753495x231214820","url":null,"abstract":"A 32-year-old Thai woman in her first pregnancy presented with multiple hyperpigmented, hyperkeratotic, pruritic, discrete papules coalescing to form plaques with a rippled pattern on the extensor surfaces of upper and lower limbs, back, chest, and abdomen. Her mother had a similar history. Histopathology of the lesion revealed a diagnosis of lichen amyloidosis, confirmed by the Congo red stain. The lesions had started one year prior and had remained stable before pregnancy; however, they became widespread after pregnancy. Thus, prompting the question as to whether this was a coincidence or if the pregnancy had exacerbated the condition. In this case report, we will discuss our approach to this patient and our opinions concerning the relationship between pregnancy and lichen amyloidosis.","PeriodicalId":51717,"journal":{"name":"Obstetric Medicine","volume":"45 4","pages":""},"PeriodicalIF":0.7,"publicationDate":"2023-11-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139276502","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The impact of socioeconomic deprivation on the prevalence of gestational diabetes: An observational study","authors":"Sai Gnanasambanthan, Salma Jabak, Retika Mohan, Nawal Dayoub, Chiamaka Maduanusi, Shuchi Kohli, Tabea Haas-Heger, Calum Lynch, Aisha Hameed","doi":"10.1177/1753495x231213920","DOIUrl":"https://doi.org/10.1177/1753495x231213920","url":null,"abstract":"Approximately 3.5% of pregnancies in the United Kingdom are complicated by gestational diabetes mellitus (GDM). Risk factors for this mirror those contributing to type 2 diabetes (T2DM). Though socioeconomic status (SES) is presumed to contribute to GDM, evidence in the United Kingdom is limited. In this unique study, we explored the impact of SES on GDM prevalence in a London suburb population. Four thousand one hundred and sixty-three pregnant women who booked between July 2018 and March 2020 at Princess Royal University Hospital were retrospectively analyzed. Associations between GDM prevalence and SES trends (using multiple deprivation deciles (MDD)), and body mass index (BMI), age, ethnicity, screening uptake, birth-weights and birth outcomes, were analyzed. Patients with BMI >30 kg/m2, older than 35 years, and non-Caucasian ethnicity have an increased risk of developing GDM ( p < 0.0001, p < 0.0001, p < 0.0001, respectively). No association existed between MDD and GDM prevalence ( p-values over 0.05). Patients with risk factors for GDM were highest in the deprived areas p < 0.0001. MDD 1–4 (most deprived) had the highest percentage of missed screening (15% of patients with risk factors missed screening), compared to 8% in the least deprived group ( p < 0.0001). Our data surprisingly suggest that low SES did not increase the incidence of GDM, despite a higher proportion of women with risk factors for GDM living in the most deprived postcodes. However this unclear finding may be due to low screening uptake of deprived populations, and therefore lack of GDM diagnosis, or indicate that GDM is a result of a different aetiology to T2DM. Further research is needed to explore if access to screening services, lack of health education or other health inequalities were responsible for the high proportion of missed screening opportunities in deprived areas.","PeriodicalId":51717,"journal":{"name":"Obstetric Medicine","volume":"21 6","pages":""},"PeriodicalIF":0.7,"publicationDate":"2023-11-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139277502","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
求助内容：
应助结果提醒方式：
京公网安备 11010802042870号
