BioMedicine-Taiwan最新文献

{"title":"Evaluation of the diagnostic value and differentiation efficacy of high sensitivity cardiac troponin T2 (hscTnT2) for STEMI and NSTEMI Iraqi patients with acute coronary syndrome","authors":"Ali Abdul Rasool Hussein, Ali Abdulateef Hasan Al-bayati, Abdulkareem H. Issa","doi":"10.51248/.v43i3.2507","DOIUrl":"https://doi.org/10.51248/.v43i3.2507","url":null,"abstract":"Introduction and Aim: Two major clinical forms of acute coronary syndrome (ACS) were categorized; acute myocardial infarction (MI) showing ST-segment elevation (STEMI) with ECG, the other non-ST-segment elevation (NSTEMI). This study was designed using a new generation of high sensitivity cardiac troponin T2 (hscTnT2) in patients with acute coronary syndrome to evaluate the diagnostic value and its efficacy in differentiation of STEMI from NSTEMI.\u0000 \u0000Materials and Methods: one hundred twenty (120) patients diagnosed to have ACS were included in the study. Apparently, sixty-four (64) healthy subjects were considered as control.  ECG and body mass index (BMI) were performed. Blood analysis of levels of glucose, lipid profile and glutamic-oxaloacetic transaminase (GOT) were measured as well as estimated the human hscTnT2 concentrations by enzyme linked immunosorbent assay (ELISA).\u0000 \u0000Results:  ACS patients (STEMI & NSTEMI) showed significant high levels (hscTnT2), Cholesterol, TG, HDL, GOT, FBS and VLDL compared to control. Furthermore, (hscTnT2) serum level in STEMI 225.95 ±120.66 ng/L is significantly higher (P value <0.001) than NSEMI 102.32 ± 58.542 ng/L. the discrimination efficacy of hscTnT2 to differentiating STEMI from NSTEMI is high with cut off value 90.3 ng/L with high sensitivity.\u0000 \u0000Conclusion: The use of new generations of high sensitivity troponin T aided to reduce the time for accurate diagnosis of acute MI to less than 2 hours. The hscTnT serum value was higher in STEMI than NSTEMI patients and shown to be positively correlated with the degree of cardiac damage in ACS patients. The level of hscTnT can be considered as good discriminating diagnostic biomarkers to differentiate STEMI from NSTEMI patients.","PeriodicalId":51650,"journal":{"name":"BioMedicine-Taiwan","volume":null,"pages":null},"PeriodicalIF":1.7,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48901742","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Coconut (Cocos nucifera L.) inflorescence sap-derived sugar restores the glucose and lipid homeostasis in streptozotocin-induced diabetic Wistar rat model","authors":"Shilpa S. Shetty, Ramesh S. V., Arivalagan M., Roopashree P. G., Manikantan M. R., H. K. B., S. Kumari","doi":"10.51248/.v43i3.1453","DOIUrl":"https://doi.org/10.51248/.v43i3.1453","url":null,"abstract":"Introduction and Aim: Coconut palm sugar (CPS) is a functional food comprising unique phytonutrients such as polyphenolics, minerals, inulin, etc., and has a low glycemic index (GI). Based on its distinctive biochemical composition, it was hypothesized that CPS would provide a glucose homeostatic effect. We investigated the effects of CPS oral administration in Wistar rats with streptozotocin-induced diabetes.\u0000 \u0000Materials and Methods: Diabetic Wistar rats were administered with different doses of CPS (200,400 and 800 mg/Kg body weight) and standard gliclazide (5 mg/Kg b.w.) for 28 days. Biochemical estimations for fasting blood glucose, lipid profile and  antioxidant status were performed.\u0000 \u0000Results: Treatment with CPS significantly (P 0.001) decreased the plasma glucose levels at 120 min after glucose load. Serum blood glucose, hepatic enzymes (alanine transaminase (ALT), aspartate transaminase (AST), alkaline phosphatase (AP)), total cholesterol (TC), total triglycerides (TG), and low-density lipoprotein (LDL) levels were also decreased. However, levels of total serum protein and high-density lipoprotein (HDL) increased in a significant manner. Pancreatic enzymatic antioxidant levels were restored, and lipid peroxidation was decreased by CPS.\u0000 \u0000Conclusion: CPS showed quite a few health benefits in diabetic rats by bringing back the glucose and lipid homeostasis to normal and yielded favorable outcomes in case of oxidative stress.","PeriodicalId":51650,"journal":{"name":"BioMedicine-Taiwan","volume":null,"pages":null},"PeriodicalIF":1.7,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47701765","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Frequency of intestinal parasites among school children around Al Hawija, Kirkuk city","authors":"Neama Ali Ahmed, Abdullah Huseen Jasim","doi":"10.51248/.v43i3.3086","DOIUrl":"https://doi.org/10.51248/.v43i3.3086","url":null,"abstract":"Introduction and Aim: Intestinal parasite infections among children are a worldwide problem, particularly in developing countries. Intestinal parasitic infections can lead to several health issues including growth and physical development in children. This investigation aimed to determine the prevalence of intestinal parasites in school children residing in Al Hawija, Kirkuk. \u0000  \u0000Materials and Methods: This study, undertaken between May 2021 and October 2022, involved 247 children aged between 2 and 13 years residing at Al Hawija, Kirkuk City. Stools samples collected from these children were studied for intestinal parasitic infections.    \u0000  \u0000Results: Of the 247 children 194 (78.6%) were seen to harbor intestinal parasites. Among these, the prevalence of protozoal and helminthic infection was observed to be 152 (61.5%) and 42 (17%) respectively. Among the protozoans, the highest prevalence was seen for Entamoeba histolytica (61.8%), followed by Giardia lamblia (30.9%) and Entamoeba coli (7.2%). Similarly, among helminthes, the highest infection was by Ascaris lumbricoidis (45.2%), followed by Enterobius vermicularis (21.4%), Trichuris trichura (11.9%), Hymenolepis nana (11.9%) and Taenia spp. (9.5%). The prevalence for these parasitic infections was observed to be highest in children aged 2-5 years. \u0000  \u0000Conclusion: Children aged between 2- 5 years are prone to parasitic infections in comparison to children between 10-13 years. ","PeriodicalId":51650,"journal":{"name":"BioMedicine-Taiwan","volume":null,"pages":null},"PeriodicalIF":1.7,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47874839","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison of the effect of olive oil and its derivatives with atorvastatin in mitigating physiological and histological disorders due to hyperlipidemia in male rats","authors":"Dlawer Abdulhammed Ahmad Aljaff, Qays Assi Ahmed, Amjed Abbawe Salih","doi":"10.51248/.v43i3.2821","DOIUrl":"https://doi.org/10.51248/.v43i3.2821","url":null,"abstract":"Introduction: Hyperlipidemia destroys liver tissue, increasing liver enzymes. Increases liver extract ferritin, kidney and liver iron, while decreasing Hepcidin hormonal levels. Olive oil, hydroxytyrosol, and Atorvastatin were compared on liver enzymes, HMG-reductase activity, ferritin, hepcidin hormone, and iron deposition in liver and kidney tissues in experimental hyperlipidemic albino male rats.\u0000 \u0000Methodology: The experiment involved 50 albino rats grouped into two (control and test) of 25 rats each, then divided into 5 groups of 5 rats each. Animals in the first control group (blank) were fed the standard diet and gavaged distilled water for eight weeks, whereas the second to fifth groups of the first subgroup were fed the same standard diet for eight weeks followed by oral gavage with olive oil, hydroxytyrosol, olive oil + hydroxytyrosol, and atorvastatin, respectively, from the third week. Animals in the first test group were fed a diet containing 2% cholesterol for the duration of the experiment, whereas rats in the seventh, eighth, ninth, and tenth test groups were fed a high-cholesterol diet 2% for two weeks, followed by oral gavage with olive oil extract for the seventh group, hydroxytyrosol for the eighth group, olive oil extract + hydroxytyrosol for the ninth group, and a drug Atorvastatin for the tenth.\u0000 \u0000Results: Hyperlipidemia significantly increased the concentrations of liver enzyme in serum, ferritin and iron deposition in liver and kidney tissues, while decreasing the HMG-reductase activity and hepcidin hormonal levels in liver extract was seen in hyperlipidemia group in comparison to healthy controls. While the groups of treated animals showed a significant enhancement in each of the aforementioned factors, as olive oil extract + hydroxytyrosol outperformed all treatments.\u0000 \u0000Conclusion: Hypercholesterolemia increases liver enzymes, ferritin, and iron deposition while lowering hepcidin hormone and HMG-reductase activity. Hypercholesterolemia was mitigated by olive oil extract and hydroxytyrosol.","PeriodicalId":51650,"journal":{"name":"BioMedicine-Taiwan","volume":null,"pages":null},"PeriodicalIF":1.7,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43142852","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Antibacterial action of AgNPs produced from different isolates of Gram positive and Gram-negative bacteria on biofilm of Klebsiella pneumoniae isolated from RTI","authors":"Suaad Ali Ahmed, Hussam Mahmood Hasan, Enass Ghassan Sweedan","doi":"10.51248/.v43i3.2813","DOIUrl":"https://doi.org/10.51248/.v43i3.2813","url":null,"abstract":"Introduction and Aim: Klebsiella pneumoniae is a Gram-negative bacterium responsible for a wide range of infections, including respiratory tract infections (RTIs). This research was aimed to study the antibacterial and anti-biofilm effect of AgNPs produced by Gram positive and negative bacteria on RTIs associated with K. pneumoniae.\u0000 \u0000Materials and Methods: The biofilm formation of K.  pneumoniae was determined by tube method qualitatively from select bacterial species characterized by UV-Visible spectroscopy. The antibacterial susceptibility of the bacteria AgNPs was tested for their antibacterial and antibiofilm activity on a clinical isolate of K. pneumoniae.\u0000 \u0000Results: K. pneumoniae isolated from RTIs were strong biofilm producers.  The antibacterial activity of AgNPs synthesized from bacterial spp in this study had good antibacterial activity against K. pneumoniae. P. aeruginosa and P. mirabilis AgNPs had the strongest anti-biofilm effect, with 84% and 83%, respectively, while A. baumanii's AgNPs had the lowest (79%). AgNPs of P. aeruginosa and P. luteola showed the highest (80%) anti-biofilm action against the development of pre- and post-mature biofilms formed by K. pneumoniae, while AgNPs from S. mitis exhibited the lowest levels (69%).\u0000 \u0000Conclusion: AgNPs generated by Gram positive and Gram-negative bacteria, when exposed to K. pneumoniae isolated from RTIs had a good antibacterial impact and inhibited the formation of biofilm by K. pneumonia and hence could be used as an antibacterial agent against K. pneumoniae infecting the respiratory tract.","PeriodicalId":51650,"journal":{"name":"BioMedicine-Taiwan","volume":null,"pages":null},"PeriodicalIF":1.7,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41921614","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Molecular characterization of linezolid resistance in clinically significant isolates of coagulase negative Staphylococcus species, a hospital based study from Western Uttar Pradesh","authors":"Priyakshi Chaudhry, A. Pandey, P. Chaturvedi, Km. Sangita","doi":"10.51248/.v43i3.2721","DOIUrl":"https://doi.org/10.51248/.v43i3.2721","url":null,"abstract":"Introduction and aim: The emergence of Multidrug-resistant Coagulase-negative Staphylococcus species is a therapeutic problem. Linezolid-resistant CoNS (LRCoNS) are on a significant rise, with a global prevalence of around 2%. The acquisition of cfr (chloramphenicol-florfenicol resistance) gene  is the commonest  mechanism leading to resistance. This study aimed to determine the molecular characterization of linezolid resistance in clinically significant isolates of Coagulase Negative Staphylococci (CoNS).\u0000 \u0000Material and Methods: The 1061 clinical  isolates of CoNS were identified by standard bacteriological technique. Antibiotic sensitivity test was performed to determine the susceptibility to linezolid and those isolates with zone diameter 20 mm (linezolid screen positive) were further confirmed by the automated Vitek 2 compact system and MIC 8 microgram per mL was resistant . The cfr gene was detected in phenotypically confirmed LRCoNS.\u0000 \u0000Results: Resistant to Linezolid was seen in 2.5% of clinically important isolates of Coagulase Negative Staphylococci. The resistance was maximum in S.hemolyticus (70%), followed by S.cohnii (22.2%). Among the LRCoNS, the overall cfr gene was detected in 78% of isolates, predominantly in S.hemolyticus and S. cohnii. All the LRCoNs were also MRCoNS (methicillin resistance). However, all isolates were susceptible to glycopeptides.\u0000 \u0000Conclusion: There has been a surge of CoNS being reported from clinical samples with resistance to many important antimicrobials, including linezolid. The presence of cfr gene is the most common mechanism of resistance to linezolid. Early and correct identification of these isolates and adherence to infection control protocols will help for better clinical outcomes.","PeriodicalId":51650,"journal":{"name":"BioMedicine-Taiwan","volume":null,"pages":null},"PeriodicalIF":1.7,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45080368","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of thyroid autoimmunity markers in polycystic ovarian syndrome in women","authors":"Shaimaa Awadh Auda, Eqbal Awadh Gatea, Zainab Awaad Radhi","doi":"10.51248/.v43i3.2823","DOIUrl":"https://doi.org/10.51248/.v43i3.2823","url":null,"abstract":"Introduction and Aim: Polycystic ovarian syndrome (PCOS) is characterized by chronic anovulation and hyperandrogenism. PCOS also affects thyroid hormones, with multiple studies showing a link between autoimmune thyroid disease (AITD) and polycystic ovarian syndrome, although the exact pathophysiology of this interaction remains unknown. In this study the autoimmune thyroid indicators in women with PCOS were examined in order to demonstrate a link between polycystic ovarian syndrome and autoimmune thyroid disease.\u0000 \u0000Materials and Methods: The study included 85 polycystic ovarian syndrome (PCOS) patients and 50 controls with similar ages. Thyroid autoantibodies (anti-thyroglobulin (Anti-Tg) and anti-peroxidase (anti-TPO), thyroid hormones (free thyroxine (T4), triiodothyronine (T3), and thyroid stimulating hormone (TSH), follicle stimulating hormone (FSH), and luteinizing hormone (LH) were determined in both study groups of women.\u0000 \u0000Results: In women with polycystic ovarian syndrome (PCOS) the blood levels of anti-thyroid peroxidase antibody (anti-TPO), antithyroglobulin antibody (anti-TG)) and thyroid stimulating hormone (TSH) were higher than women without PCOS. However, no difference was observed for free thyroxine (FT4) levels among PCOS and no PCOS women.\u0000 \u0000Conclusion: Thyroid dysfunction and thyroid autoimmunity was found to be linked in women with PCOS.  ","PeriodicalId":51650,"journal":{"name":"BioMedicine-Taiwan","volume":null,"pages":null},"PeriodicalIF":1.7,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43838981","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Isolation and characterization of bacteriophage targeting Enterococcus faecalis isolated from root canal infection (in vitro study)","authors":"Maha F. Almelan, Uroba Khalid Abbas, Al-Zubidi M.","doi":"10.51248/.v43i3.2827","DOIUrl":"https://doi.org/10.51248/.v43i3.2827","url":null,"abstract":"Introduction and Aim: Enterococcus faecalis, a Gram-positive bacterium inhabits the human and animal intestinal tracts and the environment. E. faecalis in addition to being implicated in a wide variety of infections in humans is considered the most common threat associated with recurrent root canal treatment failures. In this investigation we aimed to characterize E. faecalis strains isolated from chronic endodontic infection and evaluate the effect of a bacteriophage for its capability to eliminate E. faecalis biofilm formation. \u0000  \u0000Materials and Methods: This study involved 65 chronic endodontic infection samples which were studied for the prevalence of Enterococcus faecalis. The identification of E. faecalis was accomplished by a combination of biochemical testing and the sequencing of the 16S rRNA gene. Phages isolated from cow dung samples were purified and evaluated based on their capability of preventing the development of biofilms by Enterococcus faecalis on biotic surfaces. \u0000  \u0000Results: Of the 65 chronic endodontic infection samples studied nineteen tested positive for the presence of E. faecalis. E. faecalis strain K3 was found to be vancomycin resistant. Biofilm development on abiotic surfaces by E. faecalis strain K3 was shown to be greatly reduced after exposure to the enterococcal phage BAG1. \u0000  \u0000Conclusion: This investigation shows that the E. faecalis bacteriophage BAG1 significantly decreases the growth of E. faecalis biofilm on abiotic surfaces.","PeriodicalId":51650,"journal":{"name":"BioMedicine-Taiwan","volume":null,"pages":null},"PeriodicalIF":1.7,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48912180","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Correlation of serum gamma-glutamyl transferase and serum glutathione-S-transferase with PAP smear as screening tests for cervical cancer","authors":"P. Sowkanthika, Maitreyee D. S., Joylene D’ Almeida, S. A. R., A. S. S., E. Premakumari, M. M.","doi":"10.51248/.v43i3.2834","DOIUrl":"https://doi.org/10.51248/.v43i3.2834","url":null,"abstract":"Introduction and Aim: Papanicolaou (PAP) smear has been the test of choice in screening for cervical cancer. However,  biochemical parameters such as enzymes have been analyzed for their use in screening,  diagnosis and prognosis of cervical cancer and cervical pre-malignancy. In our study we aimed to analyse serum gamma-glutamyl transferase (GGT) and Glutathione–S- transferase (GST) in screening for cervical cancer and correlate these activities with PAP smear results.\u0000 \u0000Materials and Methods: Women who tested positive (cases) or negative (controls) for PAP smear were the subjects of this study, and activities of GGT and GST were assayed in serum samples. \u0000 \u0000Results: Serum GST was significantly lower among the cases when compared to controls (p=0.005) while serum GGT did not differ significantly between the two groups.  There was no significant correlation between GGT and GST activities both in cases and controls.\u0000 \u0000Conclusion: Serum GST showed statistically significant difference between newly diagnosed cases of cervical intraepithelial neoplasia and women testing negative for cervical intraepithelial neoplasia during screening. Further evaluation of serum enzymes as biomarkers for screening, diagnosis, and prognosis, with larger sample size and comparison between healthy controls, cervical premalignant lesions and cervical cancer are required. This would go a long way in establishing enzymes as sensitive biomarkers of cervical cancer.","PeriodicalId":51650,"journal":{"name":"BioMedicine-Taiwan","volume":null,"pages":null},"PeriodicalIF":1.7,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49457370","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Assessment of the hygiene of the oral cavity in children of primary school age in Kyrgyzstan using dental indices","authors":"Na Li, A. Nakenova, O. Bolbachan, D. Ibraimova","doi":"10.51248/.v43i3.2885","DOIUrl":"https://doi.org/10.51248/.v43i3.2885","url":null,"abstract":"Introduction: Dental caries is a significant public health issue, and its solution calls for a worldwide effort that is better coordinated and more visible. The assessment of hygiene indices enables us to collect information that is sufficiently illuminating for use in primary school students' caries prevention programs. \u0000Methods: There were 450 students total, 231 boys and 219 girls, ages 6 to 12, from school No. 1 in Lebedinovka, Chui, a rural town, and school No. 4 in Bishkek, an urban city. EGOHID-2005 was used to determine objective indicators, or dental examination data. Dental indices were used to measure the degree of hygienic knowledge, the state of oral hygiene, and the extent and severity of plaque. \u0000Results: It was determined that both urban and rural students had a good level of hygiene. However, in urban school No. 4, it was 1.4 times higher than in rural school No. 1, and vice versa, rural students were more likely to have a 2.2 times higher level of poor hygiene than urban students. \u0000Conclusion: As a result, the findings are characterized by a lack of hygienic knowledge and the unhygienic state of schoolchildren's oral cavities. \u0000  \u0000 ","PeriodicalId":51650,"journal":{"name":"BioMedicine-Taiwan","volume":null,"pages":null},"PeriodicalIF":1.7,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47653563","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}