Journal of Global Infectious Diseases最新文献_第2页

Evaluating Tuberculosis Screening Tools: A Decade-Long Network Meta-Analysis of Sensitivity and Specificity with Bibliometric Insights. 评估结核病筛查工具：一个长达十年的网络荟萃分析的敏感性和特异性与文献计量学的见解。

IF 1.1

Journal of Global Infectious Diseases Pub Date : 2025-12-29 eCollection Date: 2025-10-01 DOI: 10.4103/jgid.jgid_33_25

Diana Chusna Mufida, Muhammad Farhan Hibatulloh, Muhammad Yusuf Fadhil, Deva Fitra Firdausa Anwar, Cinday Kinanti Pramusinta, Zaskia Nafisa Salma, Annisa Eka Shabrina Salsabil, Aqilla Sakanti Chandrarini

{"title":"Evaluating Tuberculosis Screening Tools: A Decade-Long Network Meta-Analysis of Sensitivity and Specificity with Bibliometric Insights.","authors":"Diana Chusna Mufida, Muhammad Farhan Hibatulloh, Muhammad Yusuf Fadhil, Deva Fitra Firdausa Anwar, Cinday Kinanti Pramusinta, Zaskia Nafisa Salma, Annisa Eka Shabrina Salsabil, Aqilla Sakanti Chandrarini","doi":"10.4103/jgid.jgid_33_25","DOIUrl":"10.4103/jgid.jgid_33_25","url":null,"abstract":"Introduction: Tuberculosis (TB) remains a significant global health challenge despite numerous innovations in diagnostic methods. Accurate early identification is essential for effective TB management and prevention of disease spread.Methods: This study combined bibliometrics and network meta-analysis (NMA) to evaluate publication trends and compare the sensitivity and specificity of various TB screening tools against the gold standard, culture. Literature searches were conducted in seven databases over the period 2014-2024. Data were analyzed using a random-effects model with adjustment for quality of evidence using Confidence in NMA.Results: Of the 22 studies that met the inclusion criteria, 13 diagnostic tools were compared in 34 direct and 44 indirect comparisons. Culture remained the method with the best accuracy. TB molecular bacterial load assay (TB-MBLA), mNGS, and RT-Mycobacterium tuberculosis (RT-MTB) performed closest to culture in terms of sensitivity and specificity, making them promising candidates for TB screening. No significant incoherence was found, but there was high inconsistency and heterogeneity.Conclusion: This study highlights that molecular methods provide rapid detection and superior diagnostic performance compared to conventional methods, while also necessitating consideration of specificity factors and the risk of overdiagnosis. These findings highlight the urgent need to prioritize affordable, rapid, and scalable TB screening tools such as TB-MBLA and RT-MTB in low-resource, high-burden settings to improve early detection and reduce transmission.","PeriodicalId":51581,"journal":{"name":"Journal of Global Infectious Diseases","volume":"17 4","pages":"176-186"},"PeriodicalIF":1.1,"publicationDate":"2025-12-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12826652/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146054587","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Challenges in Management of Pulmonary Tuberculosis in Patients with Silicosis. 矽肺患者肺结核管理的挑战。

IF 1.1

Journal of Global Infectious Diseases Pub Date : 2025-12-29 eCollection Date: 2025-10-01 DOI: 10.4103/jgid.jgid_177_25

Ramakant Dixit, Komal Srivastava

引用次数: 0

Evaluation of the Diagnostic Performance of Interleukin-6, C-reactive Protein, and Soluble Triggering Receptor Expressed on Myeloid Cells^-1, Individually and Combined, in Differentiating Candidemia from Bacteremia in Intensive Care Unit Patients. 白细胞介素-6、c反应蛋白和髓细胞表达的可溶性触发受体-1单独和联合诊断重症监护病房患者念珠菌血症和菌血症的价值评价

IF 1.1

Journal of Global Infectious Diseases Pub Date : 2025-12-29 eCollection Date: 2025-10-01 DOI: 10.4103/jgid.jgid_12_25

Eka Khuchua, Tamar Didbaridze, Nino Gvajaia, Vasil Kupradze, Giorgi Ormotsadze, Tamar Sanikidze, Nino Intskirveli, Elene Pachkoria, Tamar Megrelishvili, Levan Ratiani

{"title":"Evaluation of the Diagnostic Performance of Interleukin-6, C-reactive Protein, and Soluble Triggering Receptor Expressed on Myeloid Cells-1, Individually and Combined, in Differentiating Candidemia from Bacteremia in Intensive Care Unit Patients.","authors":"Eka Khuchua, Tamar Didbaridze, Nino Gvajaia, Vasil Kupradze, Giorgi Ormotsadze, Tamar Sanikidze, Nino Intskirveli, Elene Pachkoria, Tamar Megrelishvili, Levan Ratiani","doi":"10.4103/jgid.jgid_12_25","DOIUrl":"10.4103/jgid.jgid_12_25","url":null,"abstract":"Introduction: Differentiating candidemia from bacteremia in intensive care unit (ICU) patients is critical for effective treatment but is often delayed by reliance on conventional diagnostics like blood cultures. This study evaluates the diagnostic utility of interleukin-6 (IL-6), C-reactive protein (CRP), and soluble triggering receptor expressed on myeloid cells-1 (sTREM-1), individually and in combination, for distinguishing these bloodstream infections (BSIs).Methods: This prospective observational study included 74 ICU patients with BSIs admitted to a university-affiliated hospital between September 2023 and August 2024. Biomarker levels were measured on the 2nd day of ICU admission. Diagnostic performance was assessed using the Mann-Whitney U test, logistic regression, and receiver operating characteristic curve analysis.Results: Of the 74 patients, 54 (72.9%) had bacteremia and 20 (27.1%) had candidemia. IL-6 and sTREM-1 levels were significantly higher in candidemia (P < 0.001), whereas CRP alone did not show discriminatory power (P = 0.981). The combined biomarker model achieved an area under the curve of 0.818, demonstrating superior diagnostic performance compared to individual markers.Conclusions: IL-6 and sTREM-1 are effective biomarkers for distinguishing candidemia from bacteremia, with CRP providing additional value in a multibiomarker model. This approach may enhance diagnostic precision and improve clinical decision-making in ICU settings.","PeriodicalId":51581,"journal":{"name":"Journal of Global Infectious Diseases","volume":"17 4","pages":"169-175"},"PeriodicalIF":1.1,"publicationDate":"2025-12-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12826643/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146054673","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Prevalence and Risk Factors of Liver Fibrosis in People Living with HIV/Acquired Immunodeficiency Syndrome. HIV/获得性免疫缺陷综合征患者肝纤维化的患病率及危险因素

IF 1.1

Journal of Global Infectious Diseases Pub Date : 2025-12-29 eCollection Date: 2025-10-01 DOI: 10.4103/jgid.jgid_87_25

Drupad Das, Mukesh Bairwa, Anand Sharma, Rajat Sharma, Ravi Kant

{"title":"Prevalence and Risk Factors of Liver Fibrosis in People Living with HIV/Acquired Immunodeficiency Syndrome.","authors":"Drupad Das, Mukesh Bairwa, Anand Sharma, Rajat Sharma, Ravi Kant","doi":"10.4103/jgid.jgid_87_25","DOIUrl":"10.4103/jgid.jgid_87_25","url":null,"abstract":"Introduction: With Antiretroviral therapy (ART), life expectancy in people living with HIV/acquired immunodeficiency syndrome (PLHA) has improved, shifting focus to complications like liver fibrosis. Contributing factors include HIV, ART-related metabolic changes, chronic inflammation, and co-infections (hepatitis B virus [HBV]/hepatitis C virus). However, HIV's independent role in fibrosis without traditional risk factors remains unclear. This study estimated liver fibrosis prevalence among PLHA in North India and identified associated risk factors.Methods: A cross-sectional study was conducted over 18 months at a tertiary ART center, including 354 PLHA. Liver fibrosis was assessed using FibroScan® and categorized into stages F0-F4. Laboratory tests included liver function, lipid profile, fasting glucose, glycated hemoglobin, and CD4 count. Metabolic syndrome was defined using the modified Adult Treatment Panel III of the National Cholesterol Education Program criteria. Statistical methods included Chi-square tests, Spearman correlation, and logistic regression.Results: The mean liver stiffness was 6.27 ± 1.87 kPa. Fibrosis stages included: F0-F1 (81.4%), F2 (13.6%), F3 (4.5%), and F4 (0.6%). Among HIV monoinfected patients without conventional risk factors, 12% had significant fibrosis, compared to 34% with risk factors (P < 0.001). Metabolic syndrome was the strongest independent predictor (Odds ratio = 27.86, P < 0.001). A negative correlation was observed between high-density lipoprotein and liver stiffness (ρ = -0.29, P < 0.001). No significant association was found with ART regimen, CD4 count, or viral load.Conclusion: Liver fibrosis was present in 18.7% of PLHA. Metabolic syndrome, diabetes, and HBV were key contributors. Routine fibrosis screening should be part of HIV care.","PeriodicalId":51581,"journal":{"name":"Journal of Global Infectious Diseases","volume":"17 4","pages":"200-207"},"PeriodicalIF":1.1,"publicationDate":"2025-12-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12826646/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146054785","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

State of the Globe: Multimarker Diagnostic Strategies: A Promising Leap Forward in Differentiating Candidemia from Bacteremia. 全球现状：多标记诊断策略：区分念珠菌病和菌血症的一个有希望的飞跃。

IF 1.1

Journal of Global Infectious Diseases Pub Date : 2025-12-29 eCollection Date: 2025-10-01 DOI: 10.4103/jgid.JGID-D-25-00034

Neeraj Kumar, Rose V Goncalves

引用次数: 0

Assessment of Rapid COVID-19 Isolation Ward Implementation in Reducing Healthcare Worker Infections. 快速实施COVID-19隔离病房减少医护人员感染的评估

IF 1.1

Journal of Global Infectious Diseases Pub Date : 2025-12-29 eCollection Date: 2025-10-01 DOI: 10.4103/jgid.jgid_70_24

Trong Zong Chen, Bi-Hua Cheng, Chien Liang Liu, Hung-Meng Huang

{"title":"Assessment of Rapid COVID-19 Isolation Ward Implementation in Reducing Healthcare Worker Infections.","authors":"Trong Zong Chen, Bi-Hua Cheng, Chien Liang Liu, Hung-Meng Huang","doi":"10.4103/jgid.jgid_70_24","DOIUrl":"10.4103/jgid.jgid_70_24","url":null,"abstract":"Introduction: Because of insufficient number of standardized negative-pressure isolation rooms to manage coronavirus disease 2019 (COVID-19), rapid deployment of a temporary isolation ward in our hospital was required. This report is intended to share our experience in the rapid deployment of a temporary isolation ward during a COVID-19 outbreak.Methods: We constructed a temporary hospital ward with 22 negative-pressure single-bed patient rooms to take care of COVID-19 patients. One-way traffic control for healthcare workers (HCWs) was designed. The temperature, humidity, and air changes per hour in each room were monitored. Each fan above ceiling of the nurse station was equipped with two ultraviolet-C (UV-C) 254 nm lamps to sterilize the environment and provide fresh air. All HCWs in the unit were tested for COVID-19 once a week by reverse transcriptase-polymerase chain reaction (RT-PCR) of nasopharyngeal samples.Results: During the period of May 31-June17, 2021, 55 patients with COVID-19 were admitted to this isolation ward, which was constructed in 2 days. The mean air changes per hour of the patient room were 11 times, and the temperature and humidity were 20.6°C and 74%, respectively. The pressure differential between the patient rooms and the corridor was 3 Pascals (Pa), lesser in the rooms. All of 966 PCR tests performed for HCWs were negative.Conclusion: The temporary COVID-19 isolation unit, constructed in 2 days, was effective for patient care and protection of HCWs.","PeriodicalId":51581,"journal":{"name":"Journal of Global Infectious Diseases","volume":"17 4","pages":"196-199"},"PeriodicalIF":1.1,"publicationDate":"2025-12-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12826641/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146054651","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A Mortise of Immune Cells: Leprosy with Disseminated Dermatophytosis. 免疫细胞的连锁反应：麻风病伴弥散性皮肤真菌病。

IF 1.1

Journal of Global Infectious Diseases Pub Date : 2025-12-29 eCollection Date: 2025-10-01 DOI: 10.4103/jgid.jgid_13_25

Sweta Singh, Amrita Upadhyaya, Sana Islahi, Shefali Gupta

引用次数: 0

Global Overview, Emerging Patterns, and Networking of West Nile Virus Research: A Scientometric Analysis. 西尼罗河病毒研究的全球概况、新出现的模式和网络：科学计量学分析。

IF 1.1

Journal of Global Infectious Diseases Pub Date : 2025-12-29 eCollection Date: 2025-10-01 DOI: 10.4103/jgid.jgid_206_24

Fran Espinoza-Carhuancho, Miguel Cabanillas-Lazo, Daniel Alvitez-Temoche, Frank Mayta-Tovalino

{"title":"Global Overview, Emerging Patterns, and Networking of West Nile Virus Research: A Scientometric Analysis.","authors":"Fran Espinoza-Carhuancho, Miguel Cabanillas-Lazo, Daniel Alvitez-Temoche, Frank Mayta-Tovalino","doi":"10.4103/jgid.jgid_206_24","DOIUrl":"10.4103/jgid.jgid_206_24","url":null,"abstract":"Introduction: The West Nile virus (WNV) has become a global concern, triggering major outbreaks in the United States and other regions. Effective surveillance and early detection are essential for controlling its spread. This study aims to assess the global landscape of WNV research, identify emerging trends, and analyze collaborative networks in the field.Methods: A comprehensive search was conducted in the Scopus database on July 14, 2024, covering publications from January 2019 to July 2024 that included specific keywords in their titles or abstracts. Metadata from 2305 documents were extracted and analyzed using SciVal and Bibliometrix, applying various indicators and metrics to evaluate research trends and collaborations.Results: The most prominent authors and institutions in this field include Ute Ziegler of the Friedrich-Loeffler Institute in Germany, Giovanni Savini of the Instituto Zooprofilattico Experimentale di Abruzzo e Molise in Italy, and Sylvie Lecollinet of the National Food Safety Agency, de l'Environnement et du Travail in France. The journals most central to WNV research include viruses and pathogens, the Journal of Medical Entomology, Vector-Borne and Zoonotic Diseases, and PLOS Neglected Tropical Diseases. The thematic evolution of WNV research reveals various key themes over time. Most publications were concentrated in the first quartile (Q1), although a decreasing trend was observed in the number of publications over time in all quartiles. The USA had the largest number of corresponding authors.Conclusion: These findings provide a comprehensive view of the scope, influence, and impact of WNV research, highlighting the importance of international collaboration in this field.","PeriodicalId":51581,"journal":{"name":"Journal of Global Infectious Diseases","volume":"17 4","pages":"208-214"},"PeriodicalIF":1.1,"publicationDate":"2025-12-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12826636/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146054726","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Hunting Trophozoites: A Rare Case of Amebiasis in an Infant. 狩猎滋养体：一个罕见的婴儿阿米巴病病例。

IF 1.1

Journal of Global Infectious Diseases Pub Date : 2025-11-10 eCollection Date: 2025-10-01 DOI: 10.4103/jgid.jgid_83_25

Seema Rao, Md Ali Osama, Nishant Wadhwa

引用次数: 0

Prevalence of Dengue Fever in Nigeria - A Scoping Review. 尼日利亚登革热流行情况-范围审查。

IF 1.1

Journal of Global Infectious Diseases Pub Date : 2025-09-22 eCollection Date: 2025-07-01 DOI: 10.4103/jgid.jgid_51_24

Kellu Bukar Ali, France Ncube, Yakub Yahaya, Yakubu Mohammed Yakub, Maryam Bukar Magu

{"title":"Prevalence of Dengue Fever in Nigeria - A Scoping Review.","authors":"Kellu Bukar Ali, France Ncube, Yakub Yahaya, Yakubu Mohammed Yakub, Maryam Bukar Magu","doi":"10.4103/jgid.jgid_51_24","DOIUrl":"10.4103/jgid.jgid_51_24","url":null,"abstract":"Introduction: Limited studies have investigated the seroprevalence of dengue viruses (DENVs) in Nigeria. Furthermore, there is no active surveillance program in place. Consequently, this study sought to determine the seroprevalence of DENV in relevant studies published in all six geopolitical zones in Nigeria.Methods: The scoping review was carried out using the Arksey and O'Malley framework. Twelve electronic databases were searched for relevant articles using a predesigned search strategy consisting of Mesh terms and Boolean search operators \"AND\" \"OR.\"Results: Out of a total of 2646 articles, 21 met the inclusion criteria. The results showed a high prevalence of dengue in Nigeria. The southeast and northwest zones had a prevalence of 70.8% and 64.8%, respectively. There was heterogeneity in the reviewed studies, in which enzyme-linked immunosorbent assay was used in 80%. Two studies used polymerase chain reaction and the detected serotypes were DENV 1 and DENV 2. The use of more than one laboratory method for the detection of DENV showed high sensitivity and specificity.Conclusion: Based on the above findings, it is deduced that dengue is hyperendemic in Nigeria, but there is no uniform data, only a few laboratory-backed seroprevalences are available in some parts of the country. Given this, it is advocated that there is a need for the public health authorities in Nigeria in collaboration with partners to establish a surveillance program to plan prevention and control efforts. It will also give evidence about the need to make vaccines available to especially those at higher risk.","PeriodicalId":51581,"journal":{"name":"Journal of Global Infectious Diseases","volume":"17 3","pages":"124-130"},"PeriodicalIF":1.1,"publicationDate":"2025-09-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12494312/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145234124","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0