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Nocardia empyema in an immunocompromised host: A case report
IF 0.8
Respiratory Medicine Case Reports Pub Date : 2025-01-01 DOI: 10.1016/j.rmcr.2025.102199
Carlos Ignacio Rodríguez Reyna , Erick Torres Luna , Ajay Sheshadri , Saadia Faiz , Lara Bashoura , Nathan Box
{"title":"Nocardia empyema in an immunocompromised host: A case report","authors":"Carlos Ignacio Rodríguez Reyna ,&nbsp;Erick Torres Luna ,&nbsp;Ajay Sheshadri ,&nbsp;Saadia Faiz ,&nbsp;Lara Bashoura ,&nbsp;Nathan Box","doi":"10.1016/j.rmcr.2025.102199","DOIUrl":"10.1016/j.rmcr.2025.102199","url":null,"abstract":"<div><div>Patients with myeloproliferative disorders such as primary myelofibrosis are at an increased risk of opportunistic infections including <em>Nocardia</em> pneumonia. <em>Nocardia</em> can become disseminated with the central nervous system being the primary site affected although any organ system can be involved. Here we present a case of <em>Nocardia</em> empyema, a rare and sparsely documented location of infection, in a post matched unrelated donor hematopoietic cell transplant patient. Further complicating this case was the presence of fungal pneumonia in the right lower lobe that led to delayed diagnosis of <em>Nocardia</em> pneumonia and empyema as non-resolving nodular opacities were thought to be worsening fungal pneumonia. This case highlights the difficulties in diagnosing <em>Nocardia</em> infections, the limitations of our diagnostic tools, the atypical presentation of empyema in an immunocompromised host, and Hickam's dictum; the idea that a patient can have multiple diagnoses occurring simultaneously.</div></div>","PeriodicalId":51565,"journal":{"name":"Respiratory Medicine Case Reports","volume":"55 ","pages":"Article 102199"},"PeriodicalIF":0.8,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143824073","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A case report: Endobronchial ultrasound guided biopsy of radiographically normal size thoracic lymph nodes supporting diagnosis of cardiac sarcoidosis 支气管超声引导下正常大小胸椎淋巴结活检支持心脏结节病诊断一例报告。
IF 0.8
Respiratory Medicine Case Reports Pub Date : 2025-01-01 DOI: 10.1016/j.rmcr.2024.102146
Jee Young You, Manuel L. Ribeiro Neto
{"title":"A case report: Endobronchial ultrasound guided biopsy of radiographically normal size thoracic lymph nodes supporting diagnosis of cardiac sarcoidosis","authors":"Jee Young You,&nbsp;Manuel L. Ribeiro Neto","doi":"10.1016/j.rmcr.2024.102146","DOIUrl":"10.1016/j.rmcr.2024.102146","url":null,"abstract":"<div><div>Sarcoidosis is a rare chronic granulomatous disease with unknown etiology. Definite diagnosis of cardiac sarcoidosis (CS) is especially difficult to establish. Several guidelines exist to make a diagnosis of CS but those have not been clinically validated. Despite the high specificity of endomyocardial biopsy, its sensitivity is low, and the severity of potential complications is high. Thus, we present 63-year-old male who was diagnosed with CS with the endobronchial ultrasound (EBUS) transbronchial needle aspiration (TBNA) of intrathoracic lymph nodes which were non-enlarged without PET avidity. EBUS TBNA of radiographically normal appearing lymph nodes showed non-necrotizing granulomas. Given challenges of diagnosing CS, EBUS TBNA can be considered even in cases without obvious evidence of active pulmonary sarcoidosis.</div></div>","PeriodicalId":51565,"journal":{"name":"Respiratory Medicine Case Reports","volume":"53 ","pages":"Article 102146"},"PeriodicalIF":0.8,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11683332/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142916252","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Pancreatopleural fistula: A rare cause of recurrent pleural effusion
IF 0.8
Respiratory Medicine Case Reports Pub Date : 2025-01-01 DOI: 10.1016/j.rmcr.2024.102163
Zehra Dhanani , Stephen Dachert
{"title":"Pancreatopleural fistula: A rare cause of recurrent pleural effusion","authors":"Zehra Dhanani ,&nbsp;Stephen Dachert","doi":"10.1016/j.rmcr.2024.102163","DOIUrl":"10.1016/j.rmcr.2024.102163","url":null,"abstract":"<div><div>Pancreatopleural fistulas, rare complications of chronic pancreatitis, are often overlooked in the initial differential diagnoses of pleural effusions, resulting in delayed diagnosis and management. We present the case of an elderly male with recurrent pleural effusion and a history of chronic pancreatitis. Diagnostic challenges arose, with the initial misdiagnosis as pneumonia. Elevated pleural fluid amylase levels (11,370U/L) along with imaging findings led to the diagnosis of a pancreatopleural fistula. This case underscores the importance of considering uncommon etiologies in pleural effusions and highlights the significance of high pleural fluid amylase levels in diagnosing pancreatopleural fistulas.</div></div>","PeriodicalId":51565,"journal":{"name":"Respiratory Medicine Case Reports","volume":"53 ","pages":"Article 102163"},"PeriodicalIF":0.8,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11757768/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143048571","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Primary malignant melanoma of the lung; a case report and literature review
IF 0.8
Respiratory Medicine Case Reports Pub Date : 2025-01-01 DOI: 10.1016/j.rmcr.2024.102161
Yub Raj Sedhai , Roshan Acharya , Priyanka Bhat , Subha Saeed , Hamza Sohail , Shreedhar Kunwar , Suman Kadariya , Muhammad Altaf Ahmed , Irfan Waheed , Rodney Steff , Tahir Muhammad Abdullah Khan , Nisar Kazimuddin , Karan Singh
{"title":"Primary malignant melanoma of the lung; a case report and literature review","authors":"Yub Raj Sedhai ,&nbsp;Roshan Acharya ,&nbsp;Priyanka Bhat ,&nbsp;Subha Saeed ,&nbsp;Hamza Sohail ,&nbsp;Shreedhar Kunwar ,&nbsp;Suman Kadariya ,&nbsp;Muhammad Altaf Ahmed ,&nbsp;Irfan Waheed ,&nbsp;Rodney Steff ,&nbsp;Tahir Muhammad Abdullah Khan ,&nbsp;Nisar Kazimuddin ,&nbsp;Karan Singh","doi":"10.1016/j.rmcr.2024.102161","DOIUrl":"10.1016/j.rmcr.2024.102161","url":null,"abstract":"<div><div>Primary pulmonary malignant melanoma is an extremely rare non-epithelial malignancy. Literature is merely limited to a few anecdotal case reports. Herein we present a case of a 74-year-old female who was diagnosed with primary malignant melanoma of the lung. To fully appraise the available evidence, we have sought to perform narrative review of the existing literature.</div></div>","PeriodicalId":51565,"journal":{"name":"Respiratory Medicine Case Reports","volume":"53 ","pages":"Article 102161"},"PeriodicalIF":0.8,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11763600/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143048575","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Addressing the consequences of missing vaccines: A case report of pertussis in a child with acute lymphoblastic leukemia
IF 0.8
Respiratory Medicine Case Reports Pub Date : 2025-01-01 DOI: 10.1016/j.rmcr.2025.102173
Diana Marcela Perea Rojas , Indiana Luz Rojas Torres , Luis Enrique Perea Vásquez
{"title":"Addressing the consequences of missing vaccines: A case report of pertussis in a child with acute lymphoblastic leukemia","authors":"Diana Marcela Perea Rojas ,&nbsp;Indiana Luz Rojas Torres ,&nbsp;Luis Enrique Perea Vásquez","doi":"10.1016/j.rmcr.2025.102173","DOIUrl":"10.1016/j.rmcr.2025.102173","url":null,"abstract":"<div><div>Pertussis, caused primarily by Bordetella pertussis and occasionally by Bordetella parapertussis, remains a major public health issue despite widespread vaccination efforts. Immunocompromised children, such as those with acute lymphoblastic leukemia, are particularly susceptible to vaccine-preventable diseases, underscoring the importance of ensuring adequate vaccination coverage. We report a case of a 3-year-old boy with ALL who developed a Bordetella parapertussis infection during chemotherapy. The child's lack of documented pertussis vaccination underscores critical gaps in primary healthcare and immunization practices. His case highlights the increased risk of severe infections in unvaccinated, immunocompromised patients and underscores the necessity of maintaining comprehensive vaccination records and robust primary healthcare systems to prevent such infections. The rapid diagnosis and initiation of appropriate antimicrobial therapy, highlights the critical role of early detection and tailored interventions in preventing severe outcomes.</div></div>","PeriodicalId":51565,"journal":{"name":"Respiratory Medicine Case Reports","volume":"53 ","pages":"Article 102173"},"PeriodicalIF":0.8,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143155574","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Clinical case of co-infection: Dengue fever and respiratory mycoplasmosis in a child
IF 0.8
Respiratory Medicine Case Reports Pub Date : 2025-01-01 DOI: 10.1016/j.rmcr.2024.102158
D.V. Preobrazhenskaia, E.V. Melekhina, Zh.B. Ponezheva
{"title":"Clinical case of co-infection: Dengue fever and respiratory mycoplasmosis in a child","authors":"D.V. Preobrazhenskaia,&nbsp;E.V. Melekhina,&nbsp;Zh.B. Ponezheva","doi":"10.1016/j.rmcr.2024.102158","DOIUrl":"10.1016/j.rmcr.2024.102158","url":null,"abstract":"<div><div>According to WHO, dengue fever (DF) is currently endemic to more than 100 countries in various regions of Africa, America, and Asia; outbreaks have been reported in Europe. In the Russian Federation, there is a much smaller proportion of children among those infected due to the imported nature of the infection.</div><div>We described a clinical case of imported dengue fever in an adolescent girl in Moscow after a 5-day vacation. Despite the fact that during the examination at the hospital in the Maldives, DENV arbovirus antigen was isolated in the blood by immunochromatographic rapid test, the course of the disease had a number of symptoms that did not conform to the classical course of the disease: catarrhal symptoms, cough, elevated C-reactive protein, and radiographic evidences of right-sided maxillary sinusitis. No improvement in the condition was observed despite the therapy administered. Additional examination confirmed an active infection caused by <em>M. pneumoniae</em>. After correction of etiotropic and pathogenetic therapy, the patient was discharged with recovery on day 10 of the disease.</div><div>After 4 years since the start of the pandemic, an increase in infectious morbidity, particularly DF, has been observed. The proportion of co-infections is increasing. Co-infection of DF and respiratory mycoplasmosis in children may occur masked as an acute respiratory viral infection (ARVI): with intensification of catarrhal and intoxication syndromes and atypical changes in laboratory parameters. All that complicates clinical and laboratory diagnosis and leads to incorrect administration of starting etiotropic therapy.</div></div>","PeriodicalId":51565,"journal":{"name":"Respiratory Medicine Case Reports","volume":"53 ","pages":"Article 102158"},"PeriodicalIF":0.8,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11754817/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143030295","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A rare case of miliary blastomycosis
IF 0.8
Respiratory Medicine Case Reports Pub Date : 2025-01-01 DOI: 10.1016/j.rmcr.2025.102203
Laura E. Ramirez , Alexander K. Foyt , Noureldien Darwish , Llewellyn Foulke , Christian Kostowniak , Amit Chopra
{"title":"A rare case of miliary blastomycosis","authors":"Laura E. Ramirez ,&nbsp;Alexander K. Foyt ,&nbsp;Noureldien Darwish ,&nbsp;Llewellyn Foulke ,&nbsp;Christian Kostowniak ,&nbsp;Amit Chopra","doi":"10.1016/j.rmcr.2025.102203","DOIUrl":"10.1016/j.rmcr.2025.102203","url":null,"abstract":"<div><div>Blastomycosis is a fungal infection caused by the fungi <em>Blastomyces dermatitidis.</em> Presentation from this infection is variable, ranging from asymptomatic cases to disseminated infection. The Capital District of New York is not traditionally considered an endemic area; however, the increasing number of reported cases suggests it may be an emerging endemic region for Blastomycosis. Thus, we present a case of pulmonary blastomycosis with a rare diffuse miliary pattern in an immunocompetent patient from CDNY. This case highlights that pulmonary blastomycosis can lead to severe disseminated infections, even in immunocompetent individuals, emphasizing the importance of heightened clinical suspicion and timely diagnosis.</div></div>","PeriodicalId":51565,"journal":{"name":"Respiratory Medicine Case Reports","volume":"55 ","pages":"Article 102203"},"PeriodicalIF":0.8,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143785668","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
First case report of isolated pleural cysticercosis demonstrating pleuroscopic findings 一例孤立性胸膜囊虫病报告，显示胸膜镜检查结果。
IF 0.8
Respiratory Medicine Case Reports Pub Date : 2025-01-01 DOI: 10.1016/j.rmcr.2024.102157
Pornchai Opartpunyasarn , Sumeth Termmathurapoj , Anan Wattanathum
{"title":"First case report of isolated pleural cysticercosis demonstrating pleuroscopic findings","authors":"Pornchai Opartpunyasarn ,&nbsp;Sumeth Termmathurapoj ,&nbsp;Anan Wattanathum","doi":"10.1016/j.rmcr.2024.102157","DOIUrl":"10.1016/j.rmcr.2024.102157","url":null,"abstract":"<div><div>Pulmonary cysticercosis is a rare manifestation of human cysticercosis, which mostly occurs in developing countries. The disease can affect the lung parenchyma and pleura, resulting in pulmonary nodules, pneumonitis, lung cavities, or pleural effusion. We herein present a case involving a man of advanced age who presented with symptomatic eosinophilic pleural effusion. A computed tomography scan of the chest showed left pleural effusion without lung parenchymal abnormalities. Pleuroscopy revealed novel findings of cysticercal pleural nodules confirmed by histological examination. The patient was diagnosed with isolated pleural cysticercosis. His symptoms and chest radiographic abnormalities improved after treatment with anthelmintic drugs.</div></div>","PeriodicalId":51565,"journal":{"name":"Respiratory Medicine Case Reports","volume":"53 ","pages":"Article 102157"},"PeriodicalIF":0.8,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11733045/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143015531","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Charcot-Marie-Tooth disease: A case report initially manifested by bilateral vocal cord paralysis
IF 0.8
Respiratory Medicine Case Reports Pub Date : 2025-01-01 DOI: 10.1016/j.rmcr.2024.102154
Seyed Hossein Mirlohi , Sanaz Tajfirooz , Mitra Rouhi
{"title":"Charcot-Marie-Tooth disease: A case report initially manifested by bilateral vocal cord paralysis","authors":"Seyed Hossein Mirlohi ,&nbsp;Sanaz Tajfirooz ,&nbsp;Mitra Rouhi","doi":"10.1016/j.rmcr.2024.102154","DOIUrl":"10.1016/j.rmcr.2024.102154","url":null,"abstract":"<div><div>Charcot-Marie-Tooth is an inherited disorder involving multiple genes, causing progressive nerve damage affecting sensation and movement. The complexity of the condition often leads to various possible diagnoses along with neuropathic diseases, sometimes resulting in significant delays in diagnosis and treatment. Thorough clinical examinations, suspicion based on symptoms, electromyography, nerve conduction tests, and specific genomic testing can expedite diagnosis. Here, we will introduce a case of Charcot-Marie-Tooth disorder, initially presenting with stridor and hoarseness due to vocal cord paralysis, later progressing to atrophy and deformity of the limbs. Diagnosis was confirmed through whole genome sequencing, revealing mutations in genes associated with the disorder.</div></div>","PeriodicalId":51565,"journal":{"name":"Respiratory Medicine Case Reports","volume":"53 ","pages":"Article 102154"},"PeriodicalIF":0.8,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11780672/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143069462","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Safety of brigatinib following alectinib-induced-pneumonitis: Case report 阿勒替尼致肺炎后布加替尼的安全性：病例报告
IF 0.8
Respiratory Medicine Case Reports Pub Date : 2025-01-01 DOI: 10.1016/j.rmcr.2024.102160
Blerina Resuli , Heidi Galarza , Laura Elsner , Diego Kauffmann-Guerrero , Jürgen Behr , Amanda Tufman
{"title":"Safety of brigatinib following alectinib-induced-pneumonitis: Case report","authors":"Blerina Resuli ,&nbsp;Heidi Galarza ,&nbsp;Laura Elsner ,&nbsp;Diego Kauffmann-Guerrero ,&nbsp;Jürgen Behr ,&nbsp;Amanda Tufman","doi":"10.1016/j.rmcr.2024.102160","DOIUrl":"10.1016/j.rmcr.2024.102160","url":null,"abstract":"<div><div>Anaplastic lymphoma kinase tyrosine kinase inhibitors (ALK TKIs) show robust efficacy and has revolutionized the treatment of NSCLC patients harboring an ALK-rearrangement. Side effects, sometimes even serious such as pneumonitis, can occur with ALK TKIs.</div><div>We report a case of a patient with ALK positive advanced NSCLC who developed pneumonitis during treatment with first-line alectinib. With no alternative etiology of pneumonitis identified, the patient was treated with corticosteroids and discontinuation of alectinib. Following rapid clinical recovery and radiographic resolution of the opacities, the patient was started with brigatinib, with no recurrence of the clinical symptoms or radiographic findings of pneumonitis. While further descriptions are needed, our experience suggests that switching to a second ALK-TKI may be a safe therapeutic option in some patients who develop drug-induced pneumonitis on ALK TKIs.</div></div>","PeriodicalId":51565,"journal":{"name":"Respiratory Medicine Case Reports","volume":"53 ","pages":"Article 102160"},"PeriodicalIF":0.8,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11743586/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143015532","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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