Filippo Sanfilippo, Cristina Santonocito, Mateusz Zawadka, Alessandro Caruso, Giovanna Bonelli, Siddharth Dugar, Philippe Vignon, Alberto Noto
{"title":"Suprasternal ascending or descending aortic velocity peak variability assessment to predict fluid-responsiveness in healthy volunteers: the SADAVA-V pilot prospective study.","authors":"Filippo Sanfilippo, Cristina Santonocito, Mateusz Zawadka, Alessandro Caruso, Giovanna Bonelli, Siddharth Dugar, Philippe Vignon, Alberto Noto","doi":"10.1007/s40477-025-01074-z","DOIUrl":"https://doi.org/10.1007/s40477-025-01074-z","url":null,"abstract":"<p><strong>Aim: </strong>Evaluating fluid responsiveness (FR) is crucial in managing critically ill patients. Measurement of respiratory variations of blood flow (V<sub>peak</sub>) is physiologically sound, but blood flow sampling through the aortic valve (AV-V<sub>peak</sub>) is not always feasible. We assessed the feasibility of suprasternal V<sub>peak</sub> (SS-V<sub>peak</sub>), at ascending or descending aorta level, as alternative to AV-V<sub>peak</sub>.</p><p><strong>Methods: </strong>Observational prospective study in spontaneously breathing healthy volunteers. We report the overall feasibility of AV- and SS-V<sub>peak</sub>, and calculated their interchangeability, the mean bias with limits of agreement (LoA) and percentage error (PE). We defined FR as a 10% increase in cardiac output measured non-invasively with finger-cuff method after passive leg raising.</p><p><strong>Results: </strong>We enrolled 67 volunteers; SS-V<sub>peak</sub> was feasible in 65 volunteers (97%), with sampling in the ascending and descending aorta in 22/65 (33.8%) and 43/65 (66.2%) volunteers, respectively. AV-V<sub>peak</sub> was feasible in 64 volunteers (95.5%). When both V<sub>peak</sub> were obtained (n = 62), interchangeability using a 12% cut-off was 67.7% (poor agreement with kappa coefficient 0.19 [-0.02;0.41]). Clinical concordance at ascending aorta level was non-significantly higher (16/22, 73% vs 26/40, 65%; p = 0.583). Prediction of FR with SS-V<sub>peak</sub> using the 12% cut-off was poor: sensitivity 85%; specificity 9%; positive predictive value 82%; negative predictive value 11%. Bland-Altman's analysis revealed a mean bias -2.6% [-4.3%;-1.0%] with LoA ranging from -15.2% [- 18.1%;- 12.4%] to 10.0% [7.2%;12.8%]. The mean PE was 7.87%.</p><p><strong>Conclusions: </strong>We report excellent feasibility for SS-V<sub>peak</sub>, though with moderate interchangeability and accuracy; however, we found poor precision and poor performances in predicting FR in healthy volunteers.</p>","PeriodicalId":51528,"journal":{"name":"Journal of Ultrasound","volume":" ","pages":""},"PeriodicalIF":1.4,"publicationDate":"2025-09-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145082490","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"An intriguing case of an unusual cystic uterine lesion: a cyst or something more?","authors":"Gaurav Bansal, Divya Drishti Sharma, Rajesh Gothi, Neha Nischal","doi":"10.1007/s40477-025-01075-y","DOIUrl":"https://doi.org/10.1007/s40477-025-01075-y","url":null,"abstract":"<p><p>Hydatid cysts infrequently affect the genital tract, with uterine involvement being exceptionally rare. Diagnosing such cases is challenging due to potentially misleading clinical and radiological findings, with confirmation often achieved only through surgical exploration and histopathological examination. In this article, we present case of a disseminated hydatid disease with rare uterine involvement.</p>","PeriodicalId":51528,"journal":{"name":"Journal of Ultrasound","volume":" ","pages":""},"PeriodicalIF":1.4,"publicationDate":"2025-09-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145058689","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Biomechanical assessment of Hoffa fat pad characteristics with ultrasound: a narrative review focusing on diagnostic imaging and image-guided interventions.","authors":"Ni Qin, Bolong Zhang, Xiaoying Zhang, Li Tian","doi":"10.1007/s40477-025-01081-0","DOIUrl":"https://doi.org/10.1007/s40477-025-01081-0","url":null,"abstract":"<p><p>The infrapatellar fat pad (IFP), a key intra-articular knee structure, plays a crucial role in biomechanical cushioning and metabolic regulation, with fibrosis and inflammation contributing to osteoarthritis-related pain and dysfunction. This review outlines the anatomy and clinical value of IFP ultrasonography in static and dynamic assessment, as well as guided interventions. Shear wave elastography (SWE), Doppler imaging, and dynamic ultrasound effectively quantify tissue stiffness, vascular signals, and flexion-extension morphology. Due to the limited penetration capability of ultrasound imaging, it is difficult to directly observe IPF through the patella. However, its real-time capability and sensitivity effectively complement the detailed anatomical information provided by MRI, making it an important supplementary method for MRI-based IPF detection. This integrated approach creates a robust diagnostic pathway, from initial assessment and precise treatment guidance to long-term monitoring. Advances in ultrasound-guided precision medicine, protocol standardization, and the integration of Artificial Intelligence (AI) with multimodal imaging hold significant promise for improving the management of IFP pathologies.</p>","PeriodicalId":51528,"journal":{"name":"Journal of Ultrasound","volume":" ","pages":""},"PeriodicalIF":1.4,"publicationDate":"2025-09-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145056205","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Temporal fossa radio- and sonoanatomy revisited: a multimodal approach to standardizing temporalis muscle thickness measurement.","authors":"Buğra İnce, Levent Özçakar","doi":"10.1007/s40477-025-01084-x","DOIUrl":"https://doi.org/10.1007/s40477-025-01084-x","url":null,"abstract":"<p><p>Temporalis muscle thickness (TMT) has gained increasing importance as a parameter for predicting sarcopenia, dysphagia, and functional outcomes, particularly in cranial pathologies such as stroke. However, the complex anatomy of the temporal fossa presents a significant challenge for the reliable assessment of TMT. This review aims to overcome this difficulty by providing a comprehensive analysis of the sonoanatomy and radiologic structure of the temporal fossa. Detailed anatomical relationship, including fascial planes, fat pads, and bony structures are presented with high-resolution images and videos. In addition to this thorough anatomical evaluation, the study introduces a novel, standardized TMT measurement technique designed to be applicable across CT, MRI, and ultrasound modalities. This technique aims to enhance the comparability of measurements and to support the use of TMT as a more effective biomarker in the evaluation and follow-up of sarcopenia, dysphagia, and other orofacial conditions.</p>","PeriodicalId":51528,"journal":{"name":"Journal of Ultrasound","volume":" ","pages":""},"PeriodicalIF":1.4,"publicationDate":"2025-09-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145058654","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Alberto Bottino, Chiara Botrugno, Ernesto Casciaro, Francesco Conversano, Aimé Lay-Ekuakille, Fiorella Anna Lombardi, Rocco Morello, Paola Pisani, Luigi Vetrugno, Sergio Casciaro
{"title":"Automatic approach for B-lines detection in lung ultrasound images using You Only Look Once algorithm.","authors":"Alberto Bottino, Chiara Botrugno, Ernesto Casciaro, Francesco Conversano, Aimé Lay-Ekuakille, Fiorella Anna Lombardi, Rocco Morello, Paola Pisani, Luigi Vetrugno, Sergio Casciaro","doi":"10.1007/s40477-025-01077-w","DOIUrl":"https://doi.org/10.1007/s40477-025-01077-w","url":null,"abstract":"<p><strong>Purpose: </strong>B-lines are among the key artifact signs observed in Lung Ultrasound (LUS), playing a critical role in differentiating pulmonary diseases and assessing overall lung condition. However, their accurate detection and quantification can be time-consuming and technically challenging, especially for less experienced operators. This study aims to evaluate the performance of a YOLO (You Only Look Once)-based algorithm for the automated detection of B-lines, offering a novel tool to support clinical decision-making. The proposed approach is designed to improve the efficiency and consistency of LUS interpretation, particularly for non-expert practitioners, and to enhance its utility in guiding respiratory management.</p><p><strong>Methods: </strong>In this observational agreement study, 644 images from both anonymized internal and clinical online database were evaluated. After a quality selection step, 386 images remained available for analysis from 46 patients. Ground truth was established by blinded expert sonographer identifying B-lines within rectangular Region Of Interest (ROI) on each frame. Algorithm performances were assessed through Precision, Recall and F1 Score, whereas to quantify the agreement between the YOLO-based algorithm and the expert operator, weighted kappa (kw) statistics were employed.</p><p><strong>Results: </strong>The algorithm achieved a precision of 0.92 (95% CI 0.89-0.94), recall of 0.81 (95% CI 0.77-0.85), and F1-score of 0.86 (95% CI 0.83-0.88). The weighted kappa was 0.68 (95% CI 0.64-0.72), indicating substantial agreement algorithm and expert annotations.</p><p><strong>Conclusions: </strong>The proposed algorithm has demonstrated its potential to significantly enhance diagnostic support by accurately detecting B-lines in LUS images.</p>","PeriodicalId":51528,"journal":{"name":"Journal of Ultrasound","volume":" ","pages":""},"PeriodicalIF":1.4,"publicationDate":"2025-09-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145042168","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Rosa Buonamassa, Emilia Cappello, Angela Di Matteo, Marcello Maestri, Sofia Frattola, Enrico Brunetti
{"title":"Ibrutinib-associated hematoma of the liver: role of ultrasound in diagnosis and clinical management.","authors":"Rosa Buonamassa, Emilia Cappello, Angela Di Matteo, Marcello Maestri, Sofia Frattola, Enrico Brunetti","doi":"10.1007/s40477-025-01059-y","DOIUrl":"https://doi.org/10.1007/s40477-025-01059-y","url":null,"abstract":"<p><p>Ibrutinib, a Bruton's tyrosine kinase (BTK) inhibitor, has transformed the management of mantle cell lymphoma (MCL) but is associated with an elevated risk of bleeding. We report a rare case of hepatic subcapsular hematoma due to ibrutinib in a patient with relapsed MCL. Ultrasound was crucial in the early detection, monitoring, and management of this rare but potentially severe complication.</p>","PeriodicalId":51528,"journal":{"name":"Journal of Ultrasound","volume":" ","pages":""},"PeriodicalIF":1.4,"publicationDate":"2025-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145024798","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Journal of UltrasoundPub Date : 2025-09-01Epub Date: 2025-03-03DOI: 10.1007/s40477-025-00999-9
Vinay Saggar, Anirudh Ramachandran, Michael Halperin, Lorena Abril, Aamir Bandagi, Ariella Gartenberg, Trevor Dixon, Nicole Leonard-Shiu, Michelle A Montenegro, Maninder Singh, Jeremy Sperling, Jonathan Maik
{"title":"Pericapsular Nerve Group block in the emergency department for hip fractures: a clinical protocol.","authors":"Vinay Saggar, Anirudh Ramachandran, Michael Halperin, Lorena Abril, Aamir Bandagi, Ariella Gartenberg, Trevor Dixon, Nicole Leonard-Shiu, Michelle A Montenegro, Maninder Singh, Jeremy Sperling, Jonathan Maik","doi":"10.1007/s40477-025-00999-9","DOIUrl":"10.1007/s40477-025-00999-9","url":null,"abstract":"<p><p>Isolated hip fractures incur significant mortality within 1 year of operative repair. Adequate analgesia is important in maintaining functional status and facilitating recovery. A multi-modal pain management strategy incorporating regional anesthesia may decrease the need for high-dose narcotics and promote faster recovery. The Pericapsular Nerve Group (PENG) block was thus developed as a regional anesthesia option for patients with hip fractures. It involves an ultrasound-guided approach that targets the anterior hip zone to provide a motor-sparing hip block. This write-up provides a sequential, step-by-step guide on how to perform the PENG block in the emergency department.</p>","PeriodicalId":51528,"journal":{"name":"Journal of Ultrasound","volume":" ","pages":"757-763"},"PeriodicalIF":1.4,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12496371/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143543469","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Evaluating the technical experience of transmuscular quadratus lumborum block in prone position: a retrospective observational study.","authors":"Sukriti Jha, Ashwin Mani, Raga Brindha, Debesh Bhoi","doi":"10.1007/s40477-025-01032-9","DOIUrl":"10.1007/s40477-025-01032-9","url":null,"abstract":"<p><strong>Background: </strong>Traditionally quadratus lumborum block has been performed in lateral or supine positions. We propose that transmuscular or anterior quadratus lumborum block performed in a prone position may offer comparable or improved technical conditions, image quality and also aid in resident training. This study aimed to assess the technical ease of performing Tm-QLB in the prone position.</p><p><strong>Methods: </strong>This retrospective study included female patients undergoing elective gynecologic oncology surgery via midline incision, who received bilateral preoperative prone-position transmuscular quadratus lumborum block. Block performance was evaluated using a composite score derived from normalized ultrasound image quality, time taken, number of attempts, and redirections. Blocks were categorized into five difficulty levels based on the composite score.</p><p><strong>Results: </strong>Ninety blocks were analyzed. Mean age was 40.18 ± 12.05 years; BMI was 23.90 ± 1.86 kg/m<sup>2</sup>. The median composite score was 0.81 (IQR: 0.17). Over 50% of blocks were rated \"Very Easy\" or \"Easy,\" reflecting high image quality, low redirection rates, and brief procedure times.</p><p><strong>Conclusion: </strong>Prone-position Tm-QLB is technically easy and operator-friendly, making it a viable alternative for training and clinical practice in suitable patients.</p>","PeriodicalId":51528,"journal":{"name":"Journal of Ultrasound","volume":" ","pages":"765-770"},"PeriodicalIF":1.4,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12496394/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144327639","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Correction to: Superb microvascular imaging (SMI) and elastosonography in thyroid nodule: diagnostic value in a real‑time cohort.","authors":"Davide Negroni, Gaetano Maddalena, Romina Bono, Flavia Abruzzese, Sara Cesano, Patrizio Conte, Chiara Airoldi, Pierluigi Neri, Alessandro Carriero","doi":"10.1007/s40477-024-00978-6","DOIUrl":"10.1007/s40477-024-00978-6","url":null,"abstract":"","PeriodicalId":51528,"journal":{"name":"Journal of Ultrasound","volume":" ","pages":"781"},"PeriodicalIF":1.4,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12496392/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142973194","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}