Ibrutinib-associated hematoma of the liver: role of ultrasound in diagnosis and clinical management.

IF 1.4 Q3 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING

Journal of Ultrasound Pub Date : 2025-09-09 DOI:10.1007/s40477-025-01059-y

Rosa Buonamassa, Emilia Cappello, Angela Di Matteo, Marcello Maestri, Sofia Frattola, Enrico Brunetti

引用次数: 0

Abstract

Ibrutinib, a Bruton's tyrosine kinase (BTK) inhibitor, has transformed the management of mantle cell lymphoma (MCL) but is associated with an elevated risk of bleeding. We report a rare case of hepatic subcapsular hematoma due to ibrutinib in a patient with relapsed MCL. Ultrasound was crucial in the early detection, monitoring, and management of this rare but potentially severe complication.

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依鲁替尼相关的肝脏血肿：超声在诊断和临床处理中的作用。

Ibrutinib是一种布鲁顿酪氨酸激酶（BTK）抑制剂，已经改变了套细胞淋巴瘤（MCL）的治疗，但与出血风险升高有关。我们报告一个罕见的病例肝包膜下血肿由于伊鲁替尼患者复发的MCL。超声在这种罕见但潜在严重并发症的早期发现、监测和治疗中起着至关重要的作用。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Journal of Ultrasound RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING-

CiteScore

4.10

自引率

15.00%

发文量

133

期刊介绍： The Journal of Ultrasound is the official journal of the Italian Society for Ultrasound in Medicine and Biology (SIUMB). The journal publishes original contributions (research and review articles, case reports, technical reports and letters to the editor) on significant advances in clinical diagnostic, interventional and therapeutic applications, clinical techniques, the physics, engineering and technology of ultrasound in medicine and biology, and in cross-sectional diagnostic imaging. The official language of Journal of Ultrasound is English.