Japanese Dental Science Review最新文献_第2页

Dental and oral management in the perioperative period of surgery: A scoping review 手术围手术期的牙科和口腔管理：范围综述

IF 6.6 2区医学

Japanese Dental Science Review Pub Date : 2024-04-11 DOI: 10.1016/j.jdsr.2024.03.002

Hironori Sakai , Hiroshi Kurita , Eiji Kondo , Hirokazu Tanaka , Tetsu Shimane , Masao Hashidume , Shin-Ichi Yamada

{"title":"Dental and oral management in the perioperative period of surgery: A scoping review","authors":"Hironori Sakai , Hiroshi Kurita , Eiji Kondo , Hirokazu Tanaka , Tetsu Shimane , Masao Hashidume , Shin-Ichi Yamada","doi":"10.1016/j.jdsr.2024.03.002","DOIUrl":"https://doi.org/10.1016/j.jdsr.2024.03.002","url":null,"abstract":"<div><p>Dental and oral management (DOM) is a long-established treatment modality. This scoping review aimed to narratively review previous studies, examine the effects of perioperative DOM, and identify the available evidence. A literature search was conducted using the PubMed electronic database for studies published between January 1, 2000, and March 8, 2022. The search yielded 43 studies, most of which were published in the last 10 years. The results of this study confirmed that improved perioperative oral hygiene is effective in preventing postoperative pneumonia. Our results also suggested that preoperative DOM is effective in preventing postoperative surgical site infections. Perioperative DOM is effective in reducing the incidence of postoperative pneumonia, SSI, and postsurgical complications. Further studies are needed to elucidate the various mechanism of DOM and to examine efficient intervention methods and timing.</p></div>","PeriodicalId":51334,"journal":{"name":"Japanese Dental Science Review","volume":"60 ","pages":"Pages 148-153"},"PeriodicalIF":6.6,"publicationDate":"2024-04-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1882761624000061/pdfft?md5=68a6fee97c2e957dc33b0e62c1e98847&pid=1-s2.0-S1882761624000061-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140547199","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Frequently used extraoral maxillofacial prosthetic materials and their longevity – A comprehensive review 常用口外颌面修复材料及其使用寿命--综合评述

IF 6.6 2区医学

Japanese Dental Science Review Pub Date : 2024-04-05 DOI: 10.1016/j.jdsr.2024.03.001

Lovely M. Annamma , Mariko Hattori , Islam E. Ali , Jovita Dsouza , Anam Waqar , Anshul Chugh , Yuka I. Sumita

{"title":"Frequently used extraoral maxillofacial prosthetic materials and their longevity – A comprehensive review","authors":"Lovely M. Annamma , Mariko Hattori , Islam E. Ali , Jovita Dsouza , Anam Waqar , Anshul Chugh , Yuka I. Sumita","doi":"10.1016/j.jdsr.2024.03.001","DOIUrl":"https://doi.org/10.1016/j.jdsr.2024.03.001","url":null,"abstract":"<div><p>The longevity of an extraoral prosthesis depends on its physical and mechanical properties and user maintenance. Faced with multiple outcome measures, researchers find it difficult to determine the most appropriate extraoral prosthetic material. This comprehensive review evaluates the most used extraoral prosthesis materials and qualitatively assesses their longevity and function. The study aims to identify and interpret the results of current updates on the factors that affect longevity and functionality. This comprehensive review summarizes and evaluates differences in the properties of commonly used extraoral maxillofacial prosthetic materials. The review was planned to focus on all factors related to the longevity and function of the extraoral maxillofacial prosthetics. An electronic search covered English articles in PubMed, Scopus, Google Scholar, Web of Science, and grey literature. Manual searching was also performed. Six authors participated in the screening. Search engines extracted 1107 records, and 88 studies were included for qualitative and bias assessments. Silicones are the most frequently used extraoral maxillofacial prosthetic materials. Heat-cured silicones are more color-stable than those cured at room temperature. Additional ingredients and processing techniques affect prosthesis longevity.</p></div>","PeriodicalId":51334,"journal":{"name":"Japanese Dental Science Review","volume":"60 ","pages":"Pages 137-147"},"PeriodicalIF":6.6,"publicationDate":"2024-04-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S188276162400005X/pdfft?md5=c0110c3019b2241051df16e5d904f57f&pid=1-s2.0-S188276162400005X-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140351949","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Diagnostic performance of artificial intelligence-aided caries detection on bitewing radiographs: a systematic review and meta-analysis 人工智能辅助咬翼X光片龋病检测的诊断性能：系统回顾和荟萃分析

IF 6.6 2区医学

Japanese Dental Science Review Pub Date : 2024-02-29 DOI: 10.1016/j.jdsr.2024.02.001

Nour Ammar , Jan Kühnisch

{"title":"Diagnostic performance of artificial intelligence-aided caries detection on bitewing radiographs: a systematic review and meta-analysis","authors":"Nour Ammar , Jan Kühnisch","doi":"10.1016/j.jdsr.2024.02.001","DOIUrl":"https://doi.org/10.1016/j.jdsr.2024.02.001","url":null,"abstract":"<div><p>The accuracy of artificial intelligence-aided (AI) caries diagnosis can vary considerably depending on numerous factors. This review aimed to assess the diagnostic accuracy of AI models for caries detection and classification on bitewing radiographs. Publications after 2010 were screened in five databases. A customized risk of bias (RoB) assessment tool was developed and applied to the 14 articles that met the inclusion criteria out of 935 references. Dataset sizes ranged from 112 to 3686 radiographs. While 86 % of the studies reported a model with an accuracy of ≥80 %, most exhibited unclear or high risk of bias. Three studies compared the model’s diagnostic performance to dentists, in which the models consistently showed higher average sensitivity. Five studies were included in a bivariate diagnostic random-effects meta-analysis for overall caries detection. The diagnostic odds ratio was 55.8 (95 % CI= 28.8 – 108.3), and the summary sensitivity and specificity were 0.87 (0.76 – 0.94) and 0.89 (0.75 – 0.960), respectively. Independent meta-analyses for dentin and enamel caries detection were conducted and showed sensitivities of 0.84 (0.80 – 0.87) and 0.71 (0.66 – 0.75), respectively. Despite the promising diagnostic performance of AI models, the lack of high-quality, adequately reported, and externally validated studies highlight current challenges and future research needs.</p></div>","PeriodicalId":51334,"journal":{"name":"Japanese Dental Science Review","volume":"60 ","pages":"Pages 128-136"},"PeriodicalIF":6.6,"publicationDate":"2024-02-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1882761624000048/pdfft?md5=2222a527d5cfc2e09b7d545509c0faa0&pid=1-s2.0-S1882761624000048-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139998898","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Treatment strategies for dental implant removal: A literature review 拔除牙种植体的治疗策略：文献综述

IF 6.6 2区医学

Japanese Dental Science Review Pub Date : 2024-02-23 DOI: 10.1016/j.jdsr.2024.01.002

Chihiro Masaki, Yusuke Kondo, Kei Tomoeda, Tomotaka Nodai, Takashi Munemasa, Taro Mukaibo, Ryuji Hosokawa

{"title":"Treatment strategies for dental implant removal: A literature review","authors":"Chihiro Masaki, Yusuke Kondo, Kei Tomoeda, Tomotaka Nodai, Takashi Munemasa, Taro Mukaibo, Ryuji Hosokawa","doi":"10.1016/j.jdsr.2024.01.002","DOIUrl":"https://doi.org/10.1016/j.jdsr.2024.01.002","url":null,"abstract":"<div><p>Dental implants have been widely used with success, but long-term usage sometimes leads to implant loss. The purpose of this review was to summarize the etiology of early and late failure requiring dental implant removal and the treatment strategies for the removal of failed implants and reimplantation. Early failures are often caused by patient-related factors, such as smoking, diabetes, radiotherapy, bone quality, and periodontitis of the remaining natural teeth. The most common cause of late failure is peri-implantitis, followed by implant fracture and implant malpositioning. Implants should be removed if they are mobile or if their superstructure cannot be maintained (e.g., implant fracture). For peri-implantitis, implant removal should be determined based on the patient’s age and esthetic needs, the implant site, and the severity of bone loss. Many reports have been published on implant removal techniques. The reverse torque technique should always be the first choice because of its low invasiveness. The weighted survival rate for the replacement of failed implants is 86.3%, with a much lower survival rate after the second or subsequent implantations. Therefore, patient-specific problems, such as smoking habits and bruxism, should be checked before reimplantation and controlled to the greatest extent possible.</p></div>","PeriodicalId":51334,"journal":{"name":"Japanese Dental Science Review","volume":"60 ","pages":"Pages 120-127"},"PeriodicalIF":6.6,"publicationDate":"2024-02-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1882761624000036/pdfft?md5=888807e463d2b7420b38713484e5c931&pid=1-s2.0-S1882761624000036-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139936695","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

In vivo dynamics of hard tissue-forming cell origins: Insights from Cre/loxP-based cell lineage tracing studies 硬组织形成细胞起源的体内动态：基于Cre/loxP的细胞系追踪研究的启示

IF 6.6 2区医学

Japanese Dental Science Review Pub Date : 2024-02-20 DOI: 10.1016/j.jdsr.2024.01.003

Toshihide Mizoguchi

{"title":"In vivo dynamics of hard tissue-forming cell origins: Insights from Cre/loxP-based cell lineage tracing studies","authors":"Toshihide Mizoguchi","doi":"10.1016/j.jdsr.2024.01.003","DOIUrl":"https://doi.org/10.1016/j.jdsr.2024.01.003","url":null,"abstract":"<div><p>Bone tissue provides structural support for our bodies, with the inner bone marrow (BM) acting as a hematopoietic organ. Within the BM tissue, two types of stem cells play crucial roles: mesenchymal stem cells (MSCs) (or skeletal stem cells) and hematopoietic stem cells (HSCs). These stem cells are intricately connected, where BM-MSCs give rise to bone-forming osteoblasts and serve as essential components in the BM microenvironment for sustaining HSCs. Despite the mid-20th century proposal of BM-MSCs, their <em>in vivo</em> identification remained elusive owing to a lack of tools for analyzing stemness, specifically self-renewal and multipotency. To address this challenge, Cre/loxP-based cell lineage tracing analyses are being employed. This technology facilitated the <em>in vivo</em> labeling of specific cells, enabling the tracking of their lineage, determining their stemness, and providing a deeper understanding of the <em>in vivo</em> dynamics governing stem cell populations responsible for maintaining hard tissues. This review delves into cell lineage tracing studies conducted using commonly employed genetically modified mice expressing Cre under the influence of LepR, Gli1, and Axin2 genes. These studies focus on research fields spanning long bones and oral/maxillofacial hard tissues, offering insights into the <em>in vivo</em> dynamics of stem cell populations crucial for hard tissue homeostasis.</p></div>","PeriodicalId":51334,"journal":{"name":"Japanese Dental Science Review","volume":"60 ","pages":"Pages 109-119"},"PeriodicalIF":6.6,"publicationDate":"2024-02-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1882761624000024/pdfft?md5=7889000b3f09fa410691a7b224c22164&pid=1-s2.0-S1882761624000024-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139908035","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Application of mesenchymal stem/stromal cells in periodontal regeneration: Opportunities and challenges 间充质干细胞/基质细胞在牙周再生中的应用：机遇与挑战

IF 6.6 2区医学

Japanese Dental Science Review Pub Date : 2024-01-25 DOI: 10.1016/j.jdsr.2024.01.001

Pan Gao , Mikihito Kajiya , Souta Motoike , Makoto Ikeya , Jingmei Yang

{"title":"Application of mesenchymal stem/stromal cells in periodontal regeneration: Opportunities and challenges","authors":"Pan Gao , Mikihito Kajiya , Souta Motoike , Makoto Ikeya , Jingmei Yang","doi":"10.1016/j.jdsr.2024.01.001","DOIUrl":"https://doi.org/10.1016/j.jdsr.2024.01.001","url":null,"abstract":"<div><p>Guided tissue regeneration (GTR) has been widely used in the periodontal treatment of intrabony and furcation defects for nearly four decades. The treatment outcomes have shown effectiveness in reducing pocket depth, improving attachment gain and bone filling in periodontal tissue. Although applying GTR could reconstruct the periodontal tissue, the surgical indications are relatively narrow, and some complications and race ethic problems bring new challenges. Therefore, it is challenging to achieve a consensus concerning the clinical benefits of GTR. With the appearance of stem cell-based regenerative medicine, mesenchymal stem/stromal cells (MSCs) have been considered a promising cell resource for periodontal regeneration. In this review, we highlight preclinical and clinical periodontal regeneration using MSCs derived from distinct origins, including non-odontogenic and odontogenic tissues and induced pluripotent stem cells, and discuss the transplantation procedures, therapeutic mechanisms, and concerns to evaluate the effectiveness of MSCs.</p></div>","PeriodicalId":51334,"journal":{"name":"Japanese Dental Science Review","volume":"60 ","pages":"Pages 95-108"},"PeriodicalIF":6.6,"publicationDate":"2024-01-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1882761624000012/pdfft?md5=91afd723b8261b202f34a1de9ae83cee&pid=1-s2.0-S1882761624000012-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139654193","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Application of one-piece endodontic crowns fabricated with CAD-CAM system to molars 使用 CAD-CAM 系统制作的一体式牙髓牙冠在磨牙上的应用

IF 6.6 2区医学

Japanese Dental Science Review Pub Date : 2024-01-20 DOI: 10.1016/j.jdsr.2023.12.005

Haruto Hiraba , Kensuke Nishio , Yoshimasa Takeuchi , Takashi Ito , Tetsuo Yamamori , Atsushi Kamimoto

{"title":"Application of one-piece endodontic crowns fabricated with CAD-CAM system to molars","authors":"Haruto Hiraba , Kensuke Nishio , Yoshimasa Takeuchi , Takashi Ito , Tetsuo Yamamori , Atsushi Kamimoto","doi":"10.1016/j.jdsr.2023.12.005","DOIUrl":"https://doi.org/10.1016/j.jdsr.2023.12.005","url":null,"abstract":"<div><p>Computer-aided design-computer-aided manufacturing (CAD-CAM) systems have been widely used as a fabrication method for restorations because of their high efficiency and accuracy, which significantly reduces fabrication time. However, molars with insufficient clearance or short clinical crown lengths require retention holes or grooves on the preparation, making it difficult to replicate the shapes with the CAM milling system. In these cases, restorations using the lost-wax method are selected. This article focuses on one-piece endodontic crowns (endocrowns) fabricated with a CAD-CAM system (CAD-CAM endocrowns), in which their posts and crowns are integrated. Articles from July 2012 to August 2023 were searched in PubMed with the keyword \"endocrown\". This review discusses the application of CAD-CAM endocrowns to molars from the viewpoint of model experiment (fracture resistance, adaptation) and clinical research. This technique, which allows margins and internal gaps to be set within the clinically acceptable range, is reported to be an effective way of restoring molars with high survival rates in clinical research.</p></div>","PeriodicalId":51334,"journal":{"name":"Japanese Dental Science Review","volume":"60 ","pages":"Pages 81-94"},"PeriodicalIF":6.6,"publicationDate":"2024-01-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1882761623000716/pdfft?md5=49879b785026e945e1188d48b450ace0&pid=1-s2.0-S1882761623000716-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139505307","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Time-study research on maxillofacial prosthetic treatment 颌面修复治疗的时间研究

IF 6.6 2区医学

Japanese Dental Science Review Pub Date : 2024-01-17 DOI: 10.1016/j.jdsr.2023.12.007

Mai Murase , Haruka Fujita , Meiko Oki , Fumi Yoshioka , Yuichiro Nishiyama , Tetsuo Ohyama , Chihaya Matsumoto , Satomi Usui , Yuji Sato , Tadashi Sado , Hidekazu Takahashi , Keiichi Sasaki , Miwa Matsuyama , Yuka Sumita

{"title":"Time-study research on maxillofacial prosthetic treatment","authors":"Mai Murase , Haruka Fujita , Meiko Oki , Fumi Yoshioka , Yuichiro Nishiyama , Tetsuo Ohyama , Chihaya Matsumoto , Satomi Usui , Yuji Sato , Tadashi Sado , Hidekazu Takahashi , Keiichi Sasaki , Miwa Matsuyama , Yuka Sumita","doi":"10.1016/j.jdsr.2023.12.007","DOIUrl":"https://doi.org/10.1016/j.jdsr.2023.12.007","url":null,"abstract":"<div><p>Unreasonable medical fees can cause problems such as increased medical costs, greater medical disparities, decreased medical standards, and physician shortages. To prevent such problems, it is important to set appropriate medical fees, ensure their proper use, and improve the efficiency of medical care. The treatment of patients with maxillofacial defects is generally more expensive compared with general prosthodontic treatment because it involves more materials and requires more frequently follow-ups for longer period. However, the actual time required for maxillofacial prosthetic treatment is unclear. Therefore, in this study, we aimed to clarify the amount of time spent treating maxillofacial prosthetic patients. We analyzed clinical data from patients undergoing routine maxillofacial prosthetic treatment, irrespective of difficulty level, at 8 university hospitals and 2 dental clinics. We also collected data from maxillofacial prosthodontists on the treatment time required for various Japanese health insurance items, including the fabrication of maxillofacial prostheses. The results revealed that some aspects of maxillofacial prosthetic treatment may take longer to perform and are more costly to perform than previously thought, suggesting the need for some adjustments to the health insurance reimbursement system. Maintaining an appropriate balance between expenditures and fees will greatly benefit patients and physicians, ensuring positive health outcomes and a healthy society.</p></div>","PeriodicalId":51334,"journal":{"name":"Japanese Dental Science Review","volume":"60 ","pages":"Pages 73-80"},"PeriodicalIF":6.6,"publicationDate":"2024-01-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S188276162300073X/pdfft?md5=7094ea0bc810c52ebfa75f1ed5aee098&pid=1-s2.0-S188276162300073X-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139487524","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Adjunctive aids for the detection of oral squamous cell carcinoma and oral potentially malignant disorders: A systematic review of systematic reviews 检测口腔鳞状细胞癌和口腔潜在恶性疾病的辅助工具：系统综述的系统综述

IF 6.6 2区医学

Japanese Dental Science Review Pub Date : 2024-01-11 DOI: 10.1016/j.jdsr.2023.12.004

Jeremy Lau , Guru O , Saman Warnakulasuriya , Ramesh Balasubramaniam , Agnieszka Frydrych , Omar Kujan

{"title":"Adjunctive aids for the detection of oral squamous cell carcinoma and oral potentially malignant disorders: A systematic review of systematic reviews","authors":"Jeremy Lau , Guru O , Saman Warnakulasuriya , Ramesh Balasubramaniam , Agnieszka Frydrych , Omar Kujan","doi":"10.1016/j.jdsr.2023.12.004","DOIUrl":"https://doi.org/10.1016/j.jdsr.2023.12.004","url":null,"abstract":"<div><p>This study presents the results of systematic reviews on adjunctive tools in screening and diagnosis of oral squamous cell carcinoma (OSCC) and oral potentially malignant disorders (OPMD) and to determine if the current literature supports their use as either an adjunctive tool or replacement of gold standard techniques. Systemic reviews and meta-analysis that evaluated adjunctive tools including chemiluminescence, tissue autofluorescence, tissue fluorescence spectroscopy, vital staining and cytology techniques were systematically examined using AMSTAR II. Twenty-seven systematic reviews were included. Five studies had a low quality of evidence, and nine studies had a critically low quality of evidence. This review found limited evidence to recommend chemiluminescence, tissue autofluorescence tools and vital staining as diagnostic tools, but only serve as clinical adjuncts to conventional oral examination. Cytology techniques and narrow-band imaging may be utilised as a non-invasive diagnostic adjunctive tool for the detection of OSCC and the malignant transformation of OPMD. In conclusion, this paper provides evidence on several types of adjunctive tools and provides recommendations on their use in clinical practice. These tools are considered useful as clinical adjuncts but there is insufficient evidence for their use as a diagnostic tool to replace gold standard conventional oral examination and surgical biopsy.</p></div>","PeriodicalId":51334,"journal":{"name":"Japanese Dental Science Review","volume":"60 ","pages":"Pages 53-72"},"PeriodicalIF":6.6,"publicationDate":"2024-01-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1882761623000704/pdfft?md5=c53399deba721205a818dcc1bb860835&pid=1-s2.0-S1882761623000704-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139433547","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Respiratory tract barrier dysfunction in viral-bacterial co-infection cases 病毒-细菌混合感染病例的呼吸道屏障功能障碍

IF 6.6 2区医学

Japanese Dental Science Review Pub Date : 2024-01-06 DOI: 10.1016/j.jdsr.2023.12.006

Tomoko Sumitomo , Shigetada Kawabata

{"title":"Respiratory tract barrier dysfunction in viral-bacterial co-infection cases","authors":"Tomoko Sumitomo , Shigetada Kawabata","doi":"10.1016/j.jdsr.2023.12.006","DOIUrl":"https://doi.org/10.1016/j.jdsr.2023.12.006","url":null,"abstract":"<div><p>A preceding viral infection of the respiratory tract predisposes the host to secondary bacterial pneumonia, known as a major cause of morbidity and mortality. However, the underlying mechanism of the viral-bacterial synergy that leads to disease progression has remained elusive, thus hampering the production of effective prophylactic and therapeutic intervention options. In addition to viral-induced airway epithelial damage, which allows dissemination of bacteria to the lower respiratory tract and increases their invasiveness, dysfunction of immune defense following a viral infection has been implicated as a factor for enhanced susceptibility to secondary bacterial infections. Given the proximity of the oral cavity to the respiratory tract, where viruses enter and replicate, it is also well-established that oral health status can significantly influence the initiation, progression, and pathology of respiratory viral infections. This review was conducted to focus on the dysfunction of the respiratory barrier, which plays a crucial role in providing physical and secretory barriers as well as immune defense in the context of viral-bacterial synergy. Greater understanding of barrier response to viral-bacterial co-infections, will ultimately lead to development of effective, broad-spectrum therapeutic approaches for prevention of enhanced susceptibility to these pathogens.</p></div>","PeriodicalId":51334,"journal":{"name":"Japanese Dental Science Review","volume":"60 ","pages":"Pages 44-52"},"PeriodicalIF":6.6,"publicationDate":"2024-01-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1882761623000728/pdfft?md5=3711c1ca8ae050e7b27effd0cb426558&pid=1-s2.0-S1882761623000728-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139111779","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0