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Lancet Respiratory Medicine最新文献

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Overlapping pulmonary hypertension phenotypes in smokers: a call to action 吸烟者重叠肺动脉高压表型：行动呼吁
IF 76.2 1区 医学
Lancet Respiratory Medicine Pub Date : 2025-08-14 DOI: 10.1016/s2213-2600(25)00259-0
Mohi Syed, Marc Humbert, Gabor Kovacs, Sandeep Sahay
{"title":"Overlapping pulmonary hypertension phenotypes in smokers: a call to action","authors":"Mohi Syed, Marc Humbert, Gabor Kovacs, Sandeep Sahay","doi":"10.1016/s2213-2600(25)00259-0","DOIUrl":"https://doi.org/10.1016/s2213-2600(25)00259-0","url":null,"abstract":"No Abstract","PeriodicalId":51307,"journal":{"name":"Lancet Respiratory Medicine","volume":"79 1","pages":""},"PeriodicalIF":76.2,"publicationDate":"2025-08-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144851440","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Unique perspective on cystic fibrosis at Edinburgh Fringe 独特的视角在爱丁堡边缘囊性纤维化
IF 76.2 1区 医学
Lancet Respiratory Medicine Pub Date : 2025-08-12 DOI: 10.1016/s2213-2600(25)00300-5
Peter Ranscombe
{"title":"Unique perspective on cystic fibrosis at Edinburgh Fringe","authors":"Peter Ranscombe","doi":"10.1016/s2213-2600(25)00300-5","DOIUrl":"https://doi.org/10.1016/s2213-2600(25)00300-5","url":null,"abstract":"No Abstract","PeriodicalId":51307,"journal":{"name":"Lancet Respiratory Medicine","volume":"31 1","pages":""},"PeriodicalIF":76.2,"publicationDate":"2025-08-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144825886","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
US FDA authorises Juul e-cigarette marketing, imperilling youth vaping declines 美国食品和药物管理局批准Juul电子烟营销，危及青少年吸电子烟的下降
IF 76.2 1区 医学
Lancet Respiratory Medicine Pub Date : 2025-08-06 DOI: 10.1016/s2213-2600(25)00291-7
Bryant Furlow
{"title":"US FDA authorises Juul e-cigarette marketing, imperilling youth vaping declines","authors":"Bryant Furlow","doi":"10.1016/s2213-2600(25)00291-7","DOIUrl":"https://doi.org/10.1016/s2213-2600(25)00291-7","url":null,"abstract":"No Abstract","PeriodicalId":51307,"journal":{"name":"Lancet Respiratory Medicine","volume":"99 1","pages":""},"PeriodicalIF":76.2,"publicationDate":"2025-08-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144786820","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Trump administration decimates worker health oversight 特朗普政府大幅削减了对工人健康的监管
IF 76.2 1区 医学
Lancet Respiratory Medicine Pub Date : 2025-08-01 DOI: 10.1016/s2213-2600(25)00289-9
Bryant Furlow
{"title":"Trump administration decimates worker health oversight","authors":"Bryant Furlow","doi":"10.1016/s2213-2600(25)00289-9","DOIUrl":"https://doi.org/10.1016/s2213-2600(25)00289-9","url":null,"abstract":"No Abstract","PeriodicalId":51307,"journal":{"name":"Lancet Respiratory Medicine","volume":"286 1","pages":""},"PeriodicalIF":76.2,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144763326","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Correction to Lancet Respir Med 2025; published online July 10. https://doi.org/10.1016/S2213-2600(25)00125-0 《柳叶刀呼吸医学2025》修正；7月10日在网上发表。https://doi.org/10.1016/s2213 00125 - 0 - 2600 (25)
IF 76.2 1区 医学
Lancet Respiratory Medicine Pub Date : 2025-08-01 DOI: 10.1016/s2213-2600(25)00295-4
{"title":"Correction to Lancet Respir Med 2025; published online July 10. https://doi.org/10.1016/S2213-2600(25)00125-0","authors":"","doi":"10.1016/s2213-2600(25)00295-4","DOIUrl":"https://doi.org/10.1016/s2213-2600(25)00295-4","url":null,"abstract":"<em>Lemiale V, Resche-Rigon M, Zerbib Y, et al. Adjunctive corticosteroids in non-AIDS patients with severe Pneumocystis jirovecii pneumonia (PIC): a multicentre, double-blind, randomised controlled trial.</em> Lancet Respir Med <em>2025; published online July 10. https://doi.org/10.1016/S2213-2600(25)00125-0</em>—In this Article, the seventh sentence of the fifth paragraph in the Statistical analysis section should have read “Ventilatory-free days at day 28 was calculated as ventilatory free days = 28 – x, if successfully liberated from ventilation x days after initiation…”. This correction has been made to the online version as of August 1, 2025, and will be made to the printed version.","PeriodicalId":51307,"journal":{"name":"Lancet Respiratory Medicine","volume":"27 1","pages":""},"PeriodicalIF":76.2,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144763325","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Pre-COPD: an evolving concept with practice potential copd前期：一个具有实践潜力的不断发展的概念
IF 76.2 1区 医学
Lancet Respiratory Medicine Pub Date : 2025-07-31 DOI: 10.1016/s2213-2600(25)00236-x
Dinh S Bui, Rosa Faner, George Washko, Christine Jenkins, E Haydn Walters, Shyamali C Dharmage
{"title":"Pre-COPD: an evolving concept with practice potential","authors":"Dinh S Bui, Rosa Faner, George Washko, Christine Jenkins, E Haydn Walters, Shyamali C Dharmage","doi":"10.1016/s2213-2600(25)00236-x","DOIUrl":"https://doi.org/10.1016/s2213-2600(25)00236-x","url":null,"abstract":"No Abstract","PeriodicalId":51307,"journal":{"name":"Lancet Respiratory Medicine","volume":"150 1","pages":""},"PeriodicalIF":76.2,"publicationDate":"2025-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144756372","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The walking wounded: sepsis survivors grapple with post-sepsis syndrome 行走伤员：败血症幸存者与败血症后综合症作斗争
IF 76.2 1区 医学
Lancet Respiratory Medicine Pub Date : 2025-07-31 DOI: 10.1016/s2213-2600(25)00286-3
Jackie Duda
{"title":"The walking wounded: sepsis survivors grapple with post-sepsis syndrome","authors":"Jackie Duda","doi":"10.1016/s2213-2600(25)00286-3","DOIUrl":"https://doi.org/10.1016/s2213-2600(25)00286-3","url":null,"abstract":"No Abstract","PeriodicalId":51307,"journal":{"name":"Lancet Respiratory Medicine","volume":"145 1","pages":""},"PeriodicalIF":76.2,"publicationDate":"2025-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144756368","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
RCPCH report on Clean Air Clinics RCPCH关于清洁空气诊所的报告
IF 76.2 1区 医学
Lancet Respiratory Medicine Pub Date : 2025-07-30 DOI: 10.1016/s2213-2600(25)00285-1
Udani Samarasekera
{"title":"RCPCH report on Clean Air Clinics","authors":"Udani Samarasekera","doi":"10.1016/s2213-2600(25)00285-1","DOIUrl":"https://doi.org/10.1016/s2213-2600(25)00285-1","url":null,"abstract":"No Abstract","PeriodicalId":51307,"journal":{"name":"Lancet Respiratory Medicine","volume":"20 1","pages":""},"PeriodicalIF":76.2,"publicationDate":"2025-07-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144748010","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Maximising opportunity for therapeutic success: sequential participation in cystic fibrosis nucleic acid-based therapy trials 最大化治疗成功的机会：顺序参与囊性纤维化核酸治疗试验
IF 76.2 1区 医学
Lancet Respiratory Medicine Pub Date : 2025-07-30 DOI: 10.1016/s2213-2600(25)00206-1
Nicole Mayer-Hamblett, Natanya R Kerper, John P Clancy, Jane C Davies, Jennifer L Taylor-Cousar, Scott H Donaldson, Scott C Bell, Raksha Jain, Nicholas J Simmonds, Marcus A Mall, Christopher H Goss, Jonathan H Rayment, Linda Setiawan, Joseph M Pilewski
{"title":"Maximising opportunity for therapeutic success: sequential participation in cystic fibrosis nucleic acid-based therapy trials","authors":"Nicole Mayer-Hamblett, Natanya R Kerper, John P Clancy, Jane C Davies, Jennifer L Taylor-Cousar, Scott H Donaldson, Scott C Bell, Raksha Jain, Nicholas J Simmonds, Marcus A Mall, Christopher H Goss, Jonathan H Rayment, Linda Setiawan, Joseph M Pilewski","doi":"10.1016/s2213-2600(25)00206-1","DOIUrl":"https://doi.org/10.1016/s2213-2600(25)00206-1","url":null,"abstract":"Identifying safe and effective therapies that target the underlying cause of cystic fibrosis remains a key priority for the cystic fibrosis community. CFTR modulators are first-in-class, regulatory-approved therapies that improve the function of the protein encoded by the <em>CFTR</em> gene and are associated with dramatic and sustained clinical benefits. Although approximately 90% of the population with cystic fibrosis could benefit from these therapies based on genetic eligibility, a crucial unmet need remains: developing CFTR-directed therapies for the ultra-rare population with cystic fibrosis who are not candidates for CFTR modulators due to either ineligibility or intolerance. Addressing this unmet need will depend on the clinical advancement of nucleic acid-based therapies (NABTs), a term that includes variant-specific antisense oligonucleotide therapies and variant-agnostic mRNA and DNA-based gene therapies. The clinical development of NABTs for those who are not candidates for or unable to take CFTR modulators is challenged not only by the relatively small target population, which affects feasible trial sizes, but also by unique regulatory requirements for long-term safety follow-up and the potential yet unknown short-term and long-term risks with genetic therapy cross-exposure or re-exposure. This Personal View addresses the proactive planning needed to maximise trial opportunities for the population who are not candidates for CFTR modulators, including considerations for subsequent NABT trial participation following previous NABT exposure.","PeriodicalId":51307,"journal":{"name":"Lancet Respiratory Medicine","volume":"52 1","pages":""},"PeriodicalIF":76.2,"publicationDate":"2025-07-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144747706","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Correction to Lancet Respir Med 2025; 13: e39–40 《柳叶刀呼吸医学2025》修正；13: e39-40
IF 76.2 1区 医学
Lancet Respiratory Medicine Pub Date : 2025-07-29 DOI: 10.1016/s2213-2600(25)00261-9
{"title":"Correction to Lancet Respir Med 2025; 13: e39–40","authors":"","doi":"10.1016/s2213-2600(25)00261-9","DOIUrl":"https://doi.org/10.1016/s2213-2600(25)00261-9","url":null,"abstract":"<em>Venkatesan P. The carbon footprint of inhaled medications in Australia.</em> Lancet Respir Med <em>2025; <strong>13</strong>: e39–40</em>—In this News piece, in the second paragraph, the third and fourth sentence should read “a position paper by Wurzel and colleagues highlights that hydrofluorocarbons (HFCs) in pressurised metered dose inhalers (pMDIs) are estimated to be responsible for 13% of the UK National Health Service carbon dioxide equivalent (CO<sub>2</sub>e) emissions related to the delivery of care and 3% of total health sector emissions.” This correction has been made as of July 29, 2025.","PeriodicalId":51307,"journal":{"name":"Lancet Respiratory Medicine","volume":"52 1","pages":""},"PeriodicalIF":76.2,"publicationDate":"2025-07-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144737633","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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