Journal of Geriatric Cardiology最新文献

{"title":"A case of rapidly progressive fatal pulmonary hypertension in a patient with metastatic bladder cancer: reflections on the early recognition of pulmonary tumour thrombotic microangiopathy.","authors":"Zhi-Qing Fu, Na Sun, Li An","doi":"10.26599/1671-5411.2025.06.004","DOIUrl":"10.26599/1671-5411.2025.06.004","url":null,"abstract":"","PeriodicalId":51294,"journal":{"name":"Journal of Geriatric Cardiology","volume":"22 6","pages":"596-599"},"PeriodicalIF":1.8,"publicationDate":"2025-05-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12235008/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144602206","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Transcatheter edge-to-edge repair in Carpentier type IIIa mitral regurgitation: challenging conventional contraindications.","authors":"Wen-Hua Lei, Yu-Jia Liang, Zhen-Gang Zhao, Mao Chen","doi":"10.26599/1671-5411.2025.06.005","DOIUrl":"10.26599/1671-5411.2025.06.005","url":null,"abstract":"","PeriodicalId":51294,"journal":{"name":"Journal of Geriatric Cardiology","volume":"22 6","pages":"609-610"},"PeriodicalIF":1.8,"publicationDate":"2025-05-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12235009/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144602221","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Management of conduction disturbances after TAVI: the last step towards early discharge.","authors":"Guillem Muntané-Carol, Rafael Romaguera, Joan Antoni Gómez-Hospital, Jorge Nuche, François Philippon, Josep Rodés-Cabau","doi":"10.26599/1671-5411.2025.05.004","DOIUrl":"10.26599/1671-5411.2025.05.004","url":null,"abstract":"<p><p>The incidence of new-onset cardiac conduction disturbances following transcatheter aortic valve implantation (TAVI) has not decreased compared to other complications, and nowadays is by far the most frequent drawback following the procedure. Meanwhile, the global management of TAVI recipients has led to a minimalist approach with short postprocedural length of stay, which may be limited by the occurrence of late arrhythmic events in patients at high-risk. This review focuses on those strategies to overcome the conundrum between early discharge and new-onset conduction disturbances in elderly TAVI candidates and provides a perspective on future improvements in this field.</p>","PeriodicalId":51294,"journal":{"name":"Journal of Geriatric Cardiology","volume":"22 5","pages":"534-546"},"PeriodicalIF":1.8,"publicationDate":"2025-05-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12209152/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144555607","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Postdischarge cancer and mortality in patients with coronary artery disease: a retrospective cohort study.","authors":"Yi-Hao Wang, Shao-Ning Zhu, Ya-Wei Zhao, Kai-Xin Yan, Ming-Zhuang Sun, Zhi-Jun Sun, Yun-Dai Chen, Shun-Ying Hu","doi":"10.26599/1671-5411.2025.06.006","DOIUrl":"10.26599/1671-5411.2025.06.006","url":null,"abstract":"<p><strong>Background: </strong>Our understanding of the correlation between postdischarge cancer and mortality in patients with coronary artery disease (CAD) remains incomplete. The aim of this study was to investigate the relationships between postdischarge cancers and all-cause mortality and cardiovascular mortality in CAD patients.</p><p><strong>Methods: </strong>In this retrospective cohort study, 25% of CAD patients without prior cancer history who underwent coronary artery angiography between January 1, 2011 and December 31, 2015, were randomly enrolled using SPSS 26.0. Patients were monitored for the incidence of postdischarge cancer, which was defined as cancer diagnosed after the index hospitalization, survival status and cause of death. Cox regression analysis was used to explore the association between postdischarge cancer and all-cause mortality and cardiovascular mortality in CAD patients.</p><p><strong>Results: </strong>A total of 4085 patients were included in the final analysis. During a median follow-up period of 8 years, 174 patients (4.3%) developed postdischarge cancer, and 343 patients (8.4%) died. A total of 173 patients died from cardiovascular diseases. Postdischarge cancer was associated with increased all-cause mortality risk (HR = 2.653, 95% CI: 1.727-4.076, <i>P</i> < 0.001) and cardiovascular mortality risk (HR = 2.756, 95% CI: 1.470-5.167, <i>P</i> = 0.002). Postdischarge lung cancer (HR = 5.497, 95% CI: 2.922-10.343, <i>P</i> < 0.001) and gastrointestinal cancer (HR = 1.984, 95% CI: 1.049-3.750, <i>P</i> = 0.035) were associated with all-cause mortality in CAD patients. Postdischarge lung cancer was significantly associated with cardiovascular death in CAD patients (HR = 4.979, 95% CI: 2.114-11.728, <i>P</i> < 0.001), and cardiovascular death was not significantly correlated with gastrointestinal cancer or other types of cancer.</p><p><strong>Conclusions: </strong>Postdischarge cancer was associated with all-cause mortality and cardiovascular mortality in CAD patients. Compared with other cancers, postdischarge lung cancer had a more significant effect on all-cause mortality and cardiovascular mortality in CAD patients.</p>","PeriodicalId":51294,"journal":{"name":"Journal of Geriatric Cardiology","volume":"22 6","pages":"578-586"},"PeriodicalIF":1.8,"publicationDate":"2025-05-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12235010/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144602211","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prognostic value of quantitative flow ratio measured immediately after percutaneous coronary intervention for chronic total occlusion.","authors":"Zheng Qiao, Zhang-Yu Lin, Qian-Qian Liu, Rui Zhang, Chang-Dong Guan, Sheng Yuan, Tong-Qiang Zou, Xiao-Hui Bian, Li-Hua Xie, Cheng-Gang Zhu, Hao-Yu Wang, Guo-Feng Gao, Ke-Fei Dou","doi":"10.26599/1671-5411.2025.04.001","DOIUrl":"https://doi.org/10.26599/1671-5411.2025.04.001","url":null,"abstract":"<p><strong>Background: </strong>The clinical impact of post-percutaneous coronary intervention (PCI) quantitative flow ratio (QFR) in patients treated with PCI for chronic total occlusion (CTO) was still undetermined.</p><p><strong>Methods: </strong>All CTO vessels treated with successful anatomical PCI in patients from PANDA III trial were retrospectively measured for post-PCI QFR. The primary outcome was 2-year vessel-oriented composite endpoints (VOCEs, composite of target vessel-related cardiac death, target vessel-related myocardial infarction, and ischemia-driven target vessel revascularization). Receiver operator characteristic curve analysis was conducted to identify optimal cutoff value of post-PCI QFR for predicting the 2-year VOCEs, and all vessels were stratified by this optimal cutoff value. Cox proportional hazards models were employed to calculate the hazard ratio (HR) with 95% CI.</p><p><strong>Results: </strong>Among 428 CTO vessels treated with PCI, 353 vessels (82.5%) were analyzable for post-PCI QFR. 31 VOCEs (8.7%) occurred at 2 years. Mean value of post-PCI QFR was 0.92 ± 0.13. Receiver operator characteristic curve analysis shown the optimal cutoff value of post-PCI QFR for predicting 2-year VOCEs was 0.91. The incidence of 2-year VOCEs in the vessel with post-PCI QFR < 0.91 (<i>n</i> = 91) was significantly higher compared with the vessels with post-PCI QFR ≥ 0.91 (<i>n</i> = 262) (22.0% <i>vs.</i> 4.2%, HR = 4.98, 95% CI: 2.32-10.70).</p><p><strong>Conclusions: </strong>Higher post-PCI QFR values were associated with improved prognosis in the PCI practice for coronary CTO. Achieving functionally optimal PCI results (post-PCI QFR value ≥ 0.91) tends to get better prognosis for patients with CTO lesions.</p>","PeriodicalId":51294,"journal":{"name":"Journal of Geriatric Cardiology","volume":"22 4","pages":"433-442"},"PeriodicalIF":1.8,"publicationDate":"2025-04-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12060140/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144025020","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Nonlinear association between serum albumin levels and all-cause mortality in elderly patients with chronic aortic regurgitation.","authors":"Ming-Hui Li, Qing-Rong Liu, Zhen-Yan Zhao, Hai-Yan Xu, Yong-Jian Wu","doi":"10.26599/1671-5411.2025.04.003","DOIUrl":"https://doi.org/10.26599/1671-5411.2025.04.003","url":null,"abstract":"<p><strong>Background: </strong>Low serum albumin levels are established predictors of adverse outcomes in various cardiovascular conditions. However, the role of serum albumin in mortality among elderly patients with chronic aortic regurgitation (AR) has not been thoroughly investigated. This study aims to assess the relationship between serum albumin levels and mortality in this specific patient population.</p><p><strong>Methods: </strong>Our analysis included 873 elderly AR patients from the China Valvular Heart Disease study, with baseline serum albumin measured at enrollment. Mortality outcomes were monitored for two years post-enrollment, employing a Cox proportional hazards model with a two-piecewise Cox proportional hazards framework to investigate the nonlinear relationship between serum albumin levels and all-cause mortality.</p><p><strong>Results: </strong>During the 2-year follow-up period, we observed 63 all-cause deaths. The association between serum albumin levels and all-cause mortality displayed an approximating L-shaped curve, indicating a mortality threshold at 35 g/L. For serum albumin levels below 35 g/L, each 1 g/L decrease was associated with a 25% higher risk of all-cause mortality (HR = 1.25, 95% CI: 1.07-1.45). In contrast, no significant change in mortality risk was observed when serum albumin levels were greater than or equal to 35 g/L. Moreover, when serum albumin is classified as hypoproteinemia (serum albumin < 35 g/L), the higher risks of all-cause death were observed in hypoproteinemic patients (HR = 2.93, 95% CI: 1.50-5.74). More importantly, the association between serum albumin and death was significantly stronger in overweight/obese patients (≥ 24 kg/m² <i>vs.</i> < 24 kg/m², <i>P</i> _interaction = 0.006).</p><p><strong>Conclusions: </strong>In elderly patients with AR, serum albumin levels showed an approximating L-shaped relationship with all-cause death, with thresholds of 35 g/L. Body mass index was significant effect modifiers of the association. These results suggest that serum albumin, as an inexpensive and readily available biochemical marker, may further improve the stratified risk of mortality in older AR patients.</p>","PeriodicalId":51294,"journal":{"name":"Journal of Geriatric Cardiology","volume":"22 4","pages":"423-432"},"PeriodicalIF":1.8,"publicationDate":"2025-04-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12060144/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144037790","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Convergence of relative apical hypertrophic cardiomyopathy and acute myocardial infarction in an elderly patient: a case report.","authors":"Xiao-Ya Su, Zhong Yin, Wei Dong","doi":"10.26599/1671-5411.2025.04.002","DOIUrl":"https://doi.org/10.26599/1671-5411.2025.04.002","url":null,"abstract":"","PeriodicalId":51294,"journal":{"name":"Journal of Geriatric Cardiology","volume":"22 4","pages":"458-462"},"PeriodicalIF":1.8,"publicationDate":"2025-04-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12060143/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144020570","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Bilateral sceletonized internal mammary arteries for myocardial revascularization in elderly patients.","authors":"Živojin S Jonjev, Ilija Bjeljac, Aleksandar M Milosavljević, Mirko Todić, Strahinja Mrvić, Novica Kalinić","doi":"10.26599/1671-5411.2025.04.004","DOIUrl":"https://doi.org/10.26599/1671-5411.2025.04.004","url":null,"abstract":"<p><strong>Background: </strong>Bilateral internal mammary arteries (BIMAs) as the most advanced surgical option for coronary artery bypass grafting (CABG) are usually recommended for younger patients without traditional risk factors. This study compares outcomes in propensity score-matched patients aged over 70 years who received BIMAs versus those who received a single internal mammary artery (SIMA).</p><p><strong>Methods: </strong>From 2013 to 2024, 8123 patients underwent primary CABG for multivessel coronary artery disease at our institution. BIMA grafting was performed in 1233 patients (15.17%), with <i>in situ</i> BIMA grafting in 290 patients (3.57%). For <i>in situ</i> BIMA group, the right internal mammary artery was used to revascularize the right coronary artery, while the left internal mammary artery was utilized for the left anterior descending artery. BIMA patients aged over 70 years (<i>n</i> = 79) were compared with SIMA patients (<i>n</i> = 79) using propensity score matching. Primary outcome was all-cause mortality at 30 days and 8 years. Secondary outcomes included length of hospital stay, incidence of postoperative major adverse cardiovascular and cerebrovascular events, sternal wound infection and the need for subsequent percutaneous revascularization.</p><p><strong>Results: </strong>There was no difference in immediate postoperative primary and secondary outcomes. Mean follow-up was 8.3 ± 1.0 years with an 8-year freedom from death of 67.08% ± 1.1% in the BIMA group versus 58.22% ± 0.9% in the SIMA group (<i>P</i> < 0.05).</p><p><strong>Conclusions: </strong>BIMAs as <i>in situ</i> grafts can be successfully used in CABG for patients aged 70 years and older. Consequently, the refined techniques for constructing internal mammary artery grafts used in this study challenge traditionally accepted limitations regarding the use of BIMAs.</p>","PeriodicalId":51294,"journal":{"name":"Journal of Geriatric Cardiology","volume":"22 4","pages":"415-422"},"PeriodicalIF":1.8,"publicationDate":"2025-04-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12060145/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143991522","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Management challenges of aortic fibroelastomas in elderly patients: a dilemma between embolic risk and bleeding risk.","authors":"Nicholas Seton, Samantha Wilson, Maria Gabriela Matta","doi":"10.26599/1671-5411.2025.04.008","DOIUrl":"https://doi.org/10.26599/1671-5411.2025.04.008","url":null,"abstract":"","PeriodicalId":51294,"journal":{"name":"Journal of Geriatric Cardiology","volume":"22 4","pages":"463-464"},"PeriodicalIF":1.8,"publicationDate":"2025-04-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12060146/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144059569","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The successful implantation of CRT-D using the catheter within catheter technique in a patient with a type IIIA persistent left superior vena cava.","authors":"Bekir Serhat Yildiz, Ramazan Gunduz, Su Ozgur","doi":"10.26599/1671-5411.2025.04.005","DOIUrl":"https://doi.org/10.26599/1671-5411.2025.04.005","url":null,"abstract":"","PeriodicalId":51294,"journal":{"name":"Journal of Geriatric Cardiology","volume":"22 4","pages":"465-468"},"PeriodicalIF":1.8,"publicationDate":"2025-04-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12060147/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144057494","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}