双侧乳腺内动脉切除在老年患者心肌血运重建术中的应用。

IF 1.8 4区 医学 Q3 CARDIAC & CARDIOVASCULAR SYSTEMS
Živojin S Jonjev, Ilija Bjeljac, Aleksandar M Milosavljević, Mirko Todić, Strahinja Mrvić, Novica Kalinić
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引用次数: 0

摘要

背景:双侧乳腺内动脉(BIMAs)作为冠状动脉搭桥术(CABG)最先进的手术选择通常推荐给没有传统危险因素的年轻患者。这项研究比较了倾向评分匹配的70岁以上患者接受bima和接受单一乳腺内动脉(SIMA)治疗的结果。方法:2013年至2024年,我院8123例多支冠状动脉疾病患者行原发性冠脉搭桥治疗。BIMA移植1233例(15.17%),原位BIMA移植290例(3.57%)。原位BIMA组采用右乳内动脉重建右冠状动脉血运,左乳内动脉重建左前降支。采用倾向评分匹配法将70岁以上BIMA患者(n = 79)与SIMA患者(n = 79)进行比较。主要结局是30天和8年的全因死亡率。次要结局包括住院时间、术后主要不良心脑血管事件的发生率、胸骨伤口感染和后续经皮血运重建术的需要。结果:术后即刻主要和次要结局无差异。平均随访8.3±1.0年,BIMA组8年死亡自由率为67.08%±1.1%,SIMA组为58.22%±0.9% (P < 0.05)。结论:bima作为原位移植物可成功用于70岁及以上患者的冠脉搭桥。因此,本研究中使用的构建乳腺内动脉移植物的精细技术挑战了传统上接受的关于使用BIMAs的限制。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Bilateral sceletonized internal mammary arteries for myocardial revascularization in elderly patients.

Background: Bilateral internal mammary arteries (BIMAs) as the most advanced surgical option for coronary artery bypass grafting (CABG) are usually recommended for younger patients without traditional risk factors. This study compares outcomes in propensity score-matched patients aged over 70 years who received BIMAs versus those who received a single internal mammary artery (SIMA).

Methods: From 2013 to 2024, 8123 patients underwent primary CABG for multivessel coronary artery disease at our institution. BIMA grafting was performed in 1233 patients (15.17%), with in situ BIMA grafting in 290 patients (3.57%). For in situ BIMA group, the right internal mammary artery was used to revascularize the right coronary artery, while the left internal mammary artery was utilized for the left anterior descending artery. BIMA patients aged over 70 years (n = 79) were compared with SIMA patients (n = 79) using propensity score matching. Primary outcome was all-cause mortality at 30 days and 8 years. Secondary outcomes included length of hospital stay, incidence of postoperative major adverse cardiovascular and cerebrovascular events, sternal wound infection and the need for subsequent percutaneous revascularization.

Results: There was no difference in immediate postoperative primary and secondary outcomes. Mean follow-up was 8.3 ± 1.0 years with an 8-year freedom from death of 67.08% ± 1.1% in the BIMA group versus 58.22% ± 0.9% in the SIMA group (P < 0.05).

Conclusions: BIMAs as in situ grafts can be successfully used in CABG for patients aged 70 years and older. Consequently, the refined techniques for constructing internal mammary artery grafts used in this study challenge traditionally accepted limitations regarding the use of BIMAs.

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来源期刊
Journal of Geriatric Cardiology
Journal of Geriatric Cardiology CARDIAC & CARDIOVASCULAR SYSTEMS-GERIATRICS & GERONTOLOGY
CiteScore
3.30
自引率
4.00%
发文量
1161
期刊介绍: JGC focuses on both basic research and clinical practice to the diagnosis and treatment of cardiovascular disease in the aged people, especially those with concomitant disease of other major organ-systems, such as the lungs, the kidneys, liver, central nervous system, gastrointestinal tract or endocrinology, etc.
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