Journal of Geriatric Cardiology最新文献

{"title":"Robot-assisted percutaneous coronary intervention: a prospective, multicenter, randomized controlled, non-inferiority clinical trial.","authors":"Yi Yu, Zheng Chen, Zhi-Jian Wang, Yue-Ping Li, Li-Xia Yang, Jing Qi, Jing Xie, Tao Huang, Dong-Mei Shi, Yu-Jie Zhou","doi":"10.26599/1671-5411.2025.08.008","DOIUrl":"10.26599/1671-5411.2025.08.008","url":null,"abstract":"<p><strong>Objective: </strong>To evaluate the safety and effectiveness of robot-assisted percutaneous coronary intervention (R-PCI) compared to traditional manual percutaneous coronary intervention (M-PCI).</p><p><strong>Methods: </strong>This prospective, multicenter, randomized controlled, non-inferior clinical trial enrolled patients with coronary heart disease who met the inclusion criteria and had indications for elective percutaneous coronary intervention. Participants were randomly assigned to either the R-PCI group or the M-PCI group. Primary endpoints were clinical and technical success rates. Clinical success was defined as visually estimated residual post-percutaneous coronary intervention stenosis < 30% with no 30-day major adverse cardiac events. Technical success in the R-PCI group was defined as successful completion of percutaneous coronary intervention using the ETcath200 robot-assisted system, without conversion to M-PCI in the event of a guidewire or balloon/stent catheter that was unable to cross the vessel or was poorly supported by the catheter. Secondary endpoints included total procedure time, percutaneous coronary intervention procedure time, fluoroscopy time, contrast volume, operator radiation exposure, air kerma, and dose-area product.</p><p><strong>Results: </strong>The trial enrolled 152 patients (R-PCI: 73 patients, M-PCI: 79 patients). Lesions were predominantly B2/C type (73.6%). Both groups achieved 100% clinical success rate. No major adverse cardiac events occurred during the 30-day follow-up. The R-PCI group had a technical success rate of 100%. The R-PCI group had longer total procedure and fluoroscopy times, but lower operator radiation exposure. The percutaneous coronary intervention procedure time, contrast volume, air kerma, and dose-area product were similar between the two groups.</p><p><strong>Conclusions: </strong>For certain complex lesions, performing percutaneous coronary intervention using the ETcath200 robot-assisted system is safe and effective and does not result in conversion to M-PCI.</p>","PeriodicalId":51294,"journal":{"name":"Journal of Geriatric Cardiology","volume":"22 8","pages":"725-735"},"PeriodicalIF":2.6,"publicationDate":"2025-08-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12411764/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145016704","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Expanding geriatric risk stratification in transcatheter aortic valve implantation: addressing overlooked domains.","authors":"Barina Khan, Abdullah Saad","doi":"10.26599/1671-5411.2025.08.005","DOIUrl":"10.26599/1671-5411.2025.08.005","url":null,"abstract":"","PeriodicalId":51294,"journal":{"name":"Journal of Geriatric Cardiology","volume":"22 8","pages":"751-752"},"PeriodicalIF":2.6,"publicationDate":"2025-08-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12411763/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145016610","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Geriatric health changes during the COVID-19 pandemic: impacts on body composition and vascular aging.","authors":"Bo Min Kim, Young Jin Tak, Jeong Gyu Lee, Yu Hyeon Yi, Seung-Hun Lee, Gyu Lee Kim, Young Jin Ra, Sang Yeoup Lee, Young Hye Cho, Eun Ju Park, Young In Lee, Jung In Choi, Sae Rom Lee, Ryuk Jun Kwon, Soo Min Son","doi":"10.26599/1671-5411.2025.08.007","DOIUrl":"10.26599/1671-5411.2025.08.007","url":null,"abstract":"","PeriodicalId":51294,"journal":{"name":"Journal of Geriatric Cardiology","volume":"22 8","pages":"753-756"},"PeriodicalIF":2.6,"publicationDate":"2025-08-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12411766/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145016635","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Contrast-induced delayed coronary vasospasm and optical coherence tomography-confirmed plaque rupture-induced ST-segment elevation myocardial infarction: a case series of Kounis syndrome.","authors":"Yuan Xu, Yu-Peng Wang, Yuan-Yuan Fan, Wei Fu, Ling-Yun Zu","doi":"10.26599/1671-5411.2025.08.003","DOIUrl":"10.26599/1671-5411.2025.08.003","url":null,"abstract":"","PeriodicalId":51294,"journal":{"name":"Journal of Geriatric Cardiology","volume":"22 8","pages":"746-750"},"PeriodicalIF":2.6,"publicationDate":"2025-08-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12411769/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145016683","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Caffeine and cardiovascular aging: exploring sex-specific impacts on risk and arrhythmias.","authors":"Alberto Farinetti, Antonio Manenti, Camilla Cocchi, Anna Vittoria Mattioli","doi":"10.26599/1671-5411.2025.08.001","DOIUrl":"10.26599/1671-5411.2025.08.001","url":null,"abstract":"<p><p>Caffeine is a widely consumed stimulant known for its cardiovascular and metabolic effects. However, its impact on cardiovascular risk, including arrhythmias, in older adults remains underexplored. Emerging evidence highlights sex-specific differences in caffeine metabolism, which may influence its role in cardiovascular health. This perspective examines the interaction between caffeine, hormonal changes, metabolic processes, and lifestyle factors, focusing on older women compared to men. Understanding these differences is essential for tailoring dietary and clinical recommendations to mitigate cardiovascular risks and promote healthy aging.</p>","PeriodicalId":51294,"journal":{"name":"Journal of Geriatric Cardiology","volume":"22 8","pages":"736-745"},"PeriodicalIF":2.6,"publicationDate":"2025-08-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12411768/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145016628","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Ventricular arrhythmia in an elderly patient with renal cell carcinoma: seeing the invisible with cardiac magnetic resonance.","authors":"Shing Ching, Kei Tung Wong","doi":"10.26599/1671-5411.2025.08.006","DOIUrl":"10.26599/1671-5411.2025.08.006","url":null,"abstract":"","PeriodicalId":51294,"journal":{"name":"Journal of Geriatric Cardiology","volume":"22 8","pages":"757-758"},"PeriodicalIF":2.6,"publicationDate":"2025-08-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12411767/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145016618","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Global, regional, and national epidemiology of cardiovascular diseases attributable to physical inactivity among adults aged 70 years and older from 1990 to 2021.","authors":"Cao Wang, Ben-Jun Zhou, Wei Gao, Yi-Min Li","doi":"10.26599/1671-5411.2025.08.004","DOIUrl":"10.26599/1671-5411.2025.08.004","url":null,"abstract":"<p><strong>Background: </strong>Physical inactivity is a significant yet underappreciated risk factor for cardiovascular disease (CVD), particularly among older adults. The aim of this study was to analyze the global burden of CVD attributable to physical inactivity in individuals aged 70 years and older from 1990 to 2021 using the Global Burden of Disease data.</p><p><strong>Methods: </strong>We assessed trends in disability-adjusted life years (DALYs) and deaths, decomposed changes into population growth, aging, and epidemiological factors, and examined health inequalities across sociodemographic index (SDI) regions.</p><p><strong>Results: </strong>From 1990 to 2021, a substantial rise in DALYs was observed, especially in low and middle SDI regions, with a 120.06% increase in the low SDI region, but a 23.10% decline in the high SDI region. Decomposition analysis identified population aging and growth as primary drivers for the burden, contributing 66.39% and 83.56% to the increase in middle and low SDI regions, respectively. By contrast, epidemiological improvements alleviated burden in the high SDI region (54.91%). Gender disparities persisted, with women experiencing a higher burden. Inequality analysis indicated a shift in CVD burden towards the low SDI region, with declining concentration indices for DALYs (-0.03 to -0.13) and deaths (-0.07 to -0.15). The Bayesian age-period-cohort projections suggest continued increases in DALYs and deaths through 2050, with women disproportionately affected.</p><p><strong>Conclusions: </strong>These findings highlight the urgent need for targeted interventions promoting physical activity, improving healthcare access, and implementing region-specific prevention strategies.</p>","PeriodicalId":51294,"journal":{"name":"Journal of Geriatric Cardiology","volume":"22 8","pages":"709-724"},"PeriodicalIF":2.6,"publicationDate":"2025-08-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12411765/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145016639","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical characteristics, therapeutic strategies, and outcomes in elderly patients on oral anticoagulant therapy undergoing percutaneous coronary interventions: <i>post-hoc</i> analysis of the PERSEO Registry.","authors":"Simona Minardi, Salvatore De Rosa, Nicolò Salvi, Giuseppe Andò, Giuseppe Talanas, Claudio D'angelo, Carolina Moretti, Tiziano Maria Mazza, Bernardo Cortese, Giuseppe Musumeci, Andrea Rubboli, Alessandro Sciahbasi","doi":"10.26599/1671-5411.2025.08.002","DOIUrl":"10.26599/1671-5411.2025.08.002","url":null,"abstract":"<p><strong>Background: </strong>Antithrombotic strategies after percutaneous coronary interventions (PCI) in elderly patients on oral anticoagulant therapy (OAT) are debated due to the balance between ischemic and bleeding risks. Recent guidelines recommend early transitioning from triple antithrombotic therapy to dual antithrombotic therapy, but there are limited data on elderly patients.</p><p><strong>Methods: </strong>We performed a <i>post-hoc</i> age-specific analysis of the PERSEO Registry population aimed to compare clinical features, therapeutic strategies, and outcomes of individuals aged ≥ 80 years and < 80 years who were on OAT and underwent PCI with stent. The primary endpoint was net adverse clinical events at 1-year follow-up. Secondary endpoints included major adverse cardiac and cerebral events (MACCE), major bleeding [Bleeding Academic Research Consortium (BARC) type 3-5], and clinically relevant bleeding (BARC type 2-5).</p><p><strong>Results: </strong>Among the 1234 patients enrolled, 31% of patients were aged ≥ 80 years (84 ± 3 years, 76% males). Compared to younger patients, elderly patients had higher rates of comorbidities such as hypertension, anaemia or chronic kidney disease, and atrial fibrillation was the leading indication for OAT. Elderly patients were more often discharged on dual antithrombotic therapy (23%) compared to younger patients (13%) (<i>P</i> < 0.0001). They experienced higher net adverse clinical events (38% <i>vs.</i> 21%, <i>P</i> < 0.001), MACCE (24% <i>vs.</i> 12%, <i>P</i> < 0.001), as well as higher bleeding rates. Specifically, rates of major bleeding (9% <i>vs.</i> 6%, <i>P</i> = 0.026), and clinically relevant bleeding (21% <i>vs.</i> 12%, <i>P</i> < 0.001) were significantly higher in elderly patients.</p><p><strong>Conclusions: </strong>Elderly patients on OAT undergoing PCI are a particular frail population with higher risk of MACCE and bleeding compared to younger patients despite a less aggressive antithrombotic therapy.</p>","PeriodicalId":51294,"journal":{"name":"Journal of Geriatric Cardiology","volume":"22 8","pages":"701-708"},"PeriodicalIF":2.6,"publicationDate":"2025-08-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12411762/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145016637","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Patient reported experience measures in TAVI procedures: VALVEX study.","authors":"Miryam González-Cebrian, Jose Luis Mendoza García, Ignacio Cruz-González, Sara Alonso Meléndez, Rocio Castillo Poyo, Raquel Zafrilla Nieto, Pedro L Sánchez, Cristina Ruiz Segria, Elena Calvo Barriuso","doi":"10.26599/1671-5411.2025.07.009","DOIUrl":"10.26599/1671-5411.2025.07.009","url":null,"abstract":"<p><strong>Background: </strong>Transcatheter Aortic Valve Implantation (TAVI) has changed the treatment paradigm of the aortic stenosis (AS). It has become the treatment of choice in patients with symptomatic AS and surgical high risk, and a valid alternative to surgical aortic valve replacement in patients with low and medium surgical risk. Despite numerous evidence on clinical results, indications and benefits, only a few studies analyse it from patient's perspective and the impact of TAVI on them. The objective of this study is to evaluate the experience of patients undergoing TAVI.</p><p><strong>Methods: </strong>Cross-sectional, descriptive observational study in two Spanish hospitals, with a establish Nurse TAVI program, with 100 patients undergoing TAVI. A specific questionnaire was designed (VALVEX questionnaire) and a pilot study was conducted by a multidisciplinary team of doctors, nurses and patients. The questionnaire was given to patients at 30 days after TAVI procedure during the follow up at the TAVI nurse clinic.</p><p><strong>Results: </strong>The study demonstrated a mean satisfaction of 9 for the TAVI program, with 96% of patients that would recommend TAVI to other patients. Patients scored a high satisfaction on the information received prior to the procedure. During the procedure and admission, the satisfaction was high in relation to the care received. During the follow up, satisfaction was high in relation to the role of the TAVI nurse, for the information and continuation of care during the procedure, in reducing anxiety, organising their admission and understanding the process. However, questions with less scores were related to hospital catering, delay between diagnosed and treatment, and patient decision-making process.</p><p><strong>Conclusion: </strong>The evaluation of patient experience allows us to improve the information given to the patient during their TAVI process and it can also allow patients to be more relax, aware and prepared for the procedure. Continuous follow up enables monitoring of patient recovery and helps to discuss any doubts improving patient's satisfaction. The use of PREMs and PROMs associated to TAVI pathway combined with an active participation of the patient on the design of the questionnaire is essential for keeping the patient in the centre of the TAVI pathway.</p>","PeriodicalId":51294,"journal":{"name":"Journal of Geriatric Cardiology","volume":"22 7","pages":"638-647"},"PeriodicalIF":2.6,"publicationDate":"2025-07-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12394955/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144977681","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association between long-term total sleep duration and physical activity trajectories and cardiovascular diseases among middle-aged and older adults: a 9-year longitudinal study.","authors":"Yan Li, Ya-Ling Huang, Hai-Rou Su, Gui-Bing Wu, Zhi-Xin Zhu","doi":"10.26599/1671-5411.2025.07.008","DOIUrl":"10.26599/1671-5411.2025.07.008","url":null,"abstract":"<p><strong>Background: </strong>It remains unclear whether sleep duration and physical activity (PA) trajectories in middle-aged and older adults are associated with different risks of cardiovascular diseases (CVDs). This study aimed to explore the trajectories of total sleep duration and PA among middle-aged and older Chinese adults and their impact on CVD risk.</p><p><strong>Methods: </strong>This study was based on the China Health and Retirement Longitudinal Study. 12009 adults aged 45 years and older from five waves were included. CVD events were measured by self-reports of heart disease and stroke. We first used group-based trajectory modeling to identify total sleep duration and PA trajectories from 2011 to 2020, and then employed logistic regression models to analyze their risk for CVD.</p><p><strong>Results: </strong>We identified three sleep duration and PA trajectories. The risk of heart disease increased by 33% (OR = 1.31, 95% CI: 1.12-1.53) for the short sleep duration trajectory (<i>vs.</i> moderate sleep duration trajectory), by 40% (OR = 1.40, 95% CI: 1.06-1.84) for the high decreasing PA trajectory, and by 20% (OR = 1.20, 95% CI: 1.01-1.42) for the low stable PA trajectory (<i>vs.</i> high stable PA trajectory), respectively. Similar results for stroke and CVD as the outcomes were also observed, but the higher risk of stroke in the high decreasing PA trajectory group was not statistically significant. The joint effects of sleep and PA showed lower risks of heart disease and stroke in trajectories with moderate or long sleep duration and high stable PA compared with short sleep duration and a low stable PA trajectory.</p><p><strong>Conclusions: </strong>Short total sleep duration, high decreasing PA, and low stable PA trajectories could increase the risk of CVDs among middle-aged and older adults. Long-term moderate to long total sleep durations and high stable PA trajectories might be optimal for preventing CVDs.</p>","PeriodicalId":51294,"journal":{"name":"Journal of Geriatric Cardiology","volume":"22 7","pages":"625-637"},"PeriodicalIF":2.6,"publicationDate":"2025-07-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12394957/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144977463","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}