Journal of Dermatology Research最新文献_第2页

The Weight of Traditional Therapy in The Management of Chronic Skin Diseases in Donka National Hospital 传统疗法在东卡国立医院慢性皮肤病治疗中的重要性

Journal of Dermatology Research Pub Date : 2024-02-19 DOI: 10.46889/jdr.2024.5107

Savané Moussa

{"title":"The Weight of Traditional Therapy in The Management of Chronic Skin Diseases in Donka National Hospital","authors":"Savané Moussa","doi":"10.46889/jdr.2024.5107","DOIUrl":"https://doi.org/10.46889/jdr.2024.5107","url":null,"abstract":"Chronic skin diseases affect patients’ physical, psychological and social well-being. They lead patients to seek care in conventional and traditional medicine. The aim of this study was to determine the contributions of traditional therapists in the management of patients with chronic skin diseases attending the Donka National Hospital. We have conducted a descriptive cross-sectional study from 10 January 2021 to 15 August 2023 in the Dermatology – STD Department of the Donka National Hospital.\u0000\u0000We considered a chronic skin disease to be one in which the duration of the disease is greater than or equal to 3 months, with repercussions on the daily life of the patient and/or those around him. Recruitment was exhaustive. A questionnaire was designed for this purpose. The Patient Global Impression Improvement Scale (PGI-I) was used to assess response to treatment. The contribution was considered positive if the patient had been referred by the traditional therapist to the specialist centre. Fifty-three of the 1011 patients suffering from chronic skin diseases were included, i.e. 9.23%.\u0000\u0000The mean age of the patients was 35.94 years, ranging from 5 to 80 years. The male/female sex ratio of patients was 0.70. Chronic skin diseases were autoimmune in 37.70% of cases. Only 17% of patients had been referred to a dermatologist by their traditional therapist, with good improvement noted in 37% of cases. This positive contribution needs to be reinforced by setting up a formal framework for collaboration between traditional and conventional medicine.","PeriodicalId":512642,"journal":{"name":"Journal of Dermatology Research","volume":"10 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139959113","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Dermatoscopic, Ultrasound and Histopathological Findings of Bullous Pilomatricoma: A Case Report 皮肤镜、超声波和组织病理学发现的大疱性扁平湿疣：病例报告

Journal of Dermatology Research Pub Date : 2024-02-18 DOI: 10.46889/jdr.2024.5106

Bernard Enmanuel Gonzales Caytuiro

引用次数: 0

Dermatoscopic, Ultrasound and Histopathological Findings of Bullous Pilomatricoma: A Case Report 皮肤镜、超声波和组织病理学发现的大疱性扁平湿疣：病例报告

Journal of Dermatology Research Pub Date : 2024-02-18 DOI: 10.46889/jdr.2024.5106

Bernard Enmanuel Gonzales Caytuiro

引用次数: 0

Oral Clarithromycin Therapy for Perioral Dermatitis in Children: A Retrospective Case-series Study 口服克拉霉素治疗儿童口周皮炎：一项回顾性病例系列研究

Journal of Dermatology Research Pub Date : 2024-02-17 DOI: 10.46889/jdr.2024.5105

Kenshi Yamasaki

{"title":"Oral Clarithromycin Therapy for Perioral Dermatitis in Children: A Retrospective Case-series Study","authors":"Kenshi Yamasaki","doi":"10.46889/jdr.2024.5105","DOIUrl":"https://doi.org/10.46889/jdr.2024.5105","url":null,"abstract":"Background: Effective treatments for pediatric periorificial dermatitis are limited. We assessed the clinical utility of oral Clarithromycin (CLR) in pediatric patients with periorificial dermatitis.\u0000\u0000Methods and Findings: A retrospective medical record review of pediatric patients with periorificial dermatitis was performed. A total of 39 pediatric patients with periorificial dermatitis received prescription of oral CLR during January 2021 and February 2023. The median age at diagnosis was 5.3 ± 3.9 years (interquartile rage 2-9). Except 8 who did not revisit the clinic and could not obtain safety data, none of 31 experienced adverse events during CLR meditation. Among 31 cases who revisited the clinic, we selected 25 cases for efficacy evaluation and excluded 6 cases who stopped medication by their own reason and/or did not take medication regularly as prescribed. Twenty-five cases included 13 females and 12 meles and average age was 6.2 ± 4.2 years (interquartile rage 2-9). Twenty-three cases achieved Complete Response (CR) by CLR: 18 achieved CR in 4 weeks and 5 achieved CR in 8 weeks. One case showed partial response (PR) by CLR and one case worsen after CLR administration with cessation of TCI. Among 23 CR cases, 7 cases (30%) had relapsed during 1.5 to 19 months after CR. All of relapse cases achieved CR by readministration of CLR.\u0000\u0000Conclusion: Oral clarithromycin is an effective and well tolerated therapeutic option for pediatric patients with periorificial dermatitis.","PeriodicalId":512642,"journal":{"name":"Journal of Dermatology Research","volume":"49 7","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139773822","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Oral Clarithromycin Therapy for Perioral Dermatitis in Children: A Retrospective Case-series Study 口服克拉霉素治疗儿童口周皮炎：一项回顾性病例系列研究

Journal of Dermatology Research Pub Date : 2024-02-17 DOI: 10.46889/jdr.2024.5105

Kenshi Yamasaki

{"title":"Oral Clarithromycin Therapy for Perioral Dermatitis in Children: A Retrospective Case-series Study","authors":"Kenshi Yamasaki","doi":"10.46889/jdr.2024.5105","DOIUrl":"https://doi.org/10.46889/jdr.2024.5105","url":null,"abstract":"Background: Effective treatments for pediatric periorificial dermatitis are limited. We assessed the clinical utility of oral Clarithromycin (CLR) in pediatric patients with periorificial dermatitis.\u0000\u0000Methods and Findings: A retrospective medical record review of pediatric patients with periorificial dermatitis was performed. A total of 39 pediatric patients with periorificial dermatitis received prescription of oral CLR during January 2021 and February 2023. The median age at diagnosis was 5.3 ± 3.9 years (interquartile rage 2-9). Except 8 who did not revisit the clinic and could not obtain safety data, none of 31 experienced adverse events during CLR meditation. Among 31 cases who revisited the clinic, we selected 25 cases for efficacy evaluation and excluded 6 cases who stopped medication by their own reason and/or did not take medication regularly as prescribed. Twenty-five cases included 13 females and 12 meles and average age was 6.2 ± 4.2 years (interquartile rage 2-9). Twenty-three cases achieved Complete Response (CR) by CLR: 18 achieved CR in 4 weeks and 5 achieved CR in 8 weeks. One case showed partial response (PR) by CLR and one case worsen after CLR administration with cessation of TCI. Among 23 CR cases, 7 cases (30%) had relapsed during 1.5 to 19 months after CR. All of relapse cases achieved CR by readministration of CLR.\u0000\u0000Conclusion: Oral clarithromycin is an effective and well tolerated therapeutic option for pediatric patients with periorificial dermatitis.","PeriodicalId":512642,"journal":{"name":"Journal of Dermatology Research","volume":"426 ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139833255","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Successful Control of Some Challenging Cases in Late Adult and Elderly Onset Atopic Dermatitis with Dupilumab Injection in Kuwaiti Patients: A Prospective Pilot Study 在科威特患者中使用杜匹单抗注射液成功控制晚期成人和老年特应性皮炎的一些棘手病例：一项前瞻性试点研究

Journal of Dermatology Research Pub Date : 2024-01-22 DOI: 10.46889/jdr.2024.5104

I. Almasry

{"title":"Successful Control of Some Challenging Cases in Late Adult and Elderly Onset Atopic Dermatitis with Dupilumab Injection in Kuwaiti Patients: A Prospective Pilot Study","authors":"I. Almasry","doi":"10.46889/jdr.2024.5104","DOIUrl":"https://doi.org/10.46889/jdr.2024.5104","url":null,"abstract":"Atopic Dermatitis is severely itchy skin disease with chronic prolonged course and relapsing flares, which was considered mainly infantile or childhood in onset for a long time. Atopic Dermatitis is not any more a pediatric dermatosis, an emerging new entity in adult and elderly patients became more and more identified. An elderly onset of Atopic Dermatitis is mainly due to aging process. There are various causes that reduce skin function, especially senile xerosis of skin in these age group. Dryness itself makes skin as weak as a protective barrier in elderly, in addition to pathophysiological changes in aging human skin. All previous factors might trigger Atopic Dermatitis pictures over elderly patient. Atopic Dermatitis in elderly might does not look so bad as morphological reflection on skin, but intolerable pruritus’ accompanied this skin condition is more concerned. Dupilumab as well-known safe and effective controlling therapy for atopic dermatitis, given a light at end of tunnel specially for severe pruritus’ which affect badly life quality in these poor patients. This article represents a close review of etiopathogenesis of late adult and elderly onset atopic dermatitis. Also, we represent 10 cases of confirmed late adult and elderly Atopic Dermatitis who have a proper control on Dupilumab injection safely without any drawbacks on patients.","PeriodicalId":512642,"journal":{"name":"Journal of Dermatology Research","volume":"41 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139523260","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Case Report of Hailey-Hailey Disease Successfully Treated with Topical Roflumilast 0.3% Cream 使用 0.3% 罗氟司特局部乳膏成功治疗海利-海利病的病例报告

Journal of Dermatology Research Pub Date : 2024-01-18 DOI: 10.46889/jdr.2024.5103

Klepper Em

引用次数: 0

JAK Inhibitor Baricitinib in the Treatment of Oral Lichen Planus: A Case Report JAK 抑制剂 Baricitinib 治疗口腔扁平苔藓：病例报告

Journal of Dermatology Research Pub Date : 2024-01-16 DOI: 10.46889/jdr.2024.5101

Fahad Ahmed

引用次数: 0

In An Incisional Model of Wound Healing, Genistein Aglycone Enhances Skin Recovery: A Comparison with Raloxifene and Estradiol in Ovariectomized Rats Is Presented 在伤口愈合切口模型中，染料木苷苷元苷元可促进皮肤恢复：在卵巢切除大鼠中与雷洛昔芬和雌二醇进行比较

Journal of Dermatology Research Pub Date : 2024-01-16 DOI: 10.46889/jdr.2024.5102

Hari Prasad Sonwani

{"title":"In An Incisional Model of Wound Healing, Genistein Aglycone Enhances Skin Recovery: A Comparison with Raloxifene and Estradiol in Ovariectomized Rats Is Presented","authors":"Hari Prasad Sonwani","doi":"10.46889/jdr.2024.5102","DOIUrl":"https://doi.org/10.46889/jdr.2024.5102","url":null,"abstract":"Context and goal: Poor wound healing is commonly associated with estrogen depletion during menopause. Experiments on anti-aging cosmetic formulations using genistein have yielded intriguing findings about skin health. Here, we examined the effects of systemically administered the genistein aglycones in an incisional wound healing model in comparison to systemically administered estradiol and raloxifene. Method of experimentation: Rats were randomly divided into groups of 12 animals each six months after Ovariectomies (OVX) and given daily treatments of raloxifene hydrochloride (0.05 and 0.5 mg·kg-1s.c.), genistein aglycone (1 and 10 mg·kg-1s.c.) or 17-a-ethinyl estradiol (0.003 and 0.03 mg·kg-1s.c.) for a period of 12 weeks. Rats with OVX and sham OVX were not treated and served as controls. Then, an incisional wound healing technique was carried out 14 or 7 days before to the experiment’s conclusion and skin specimens were gathered to assess molecular, histological and functional measurements. Important Results: Compared to samples from sham OVX animals, samples from OVX rats seven and fourteen days after wounding shown a decrease in transforming growthfactor-b1, tissue transglutaminase 2 and vascular endothelial growth factor. Genistein, raloxifene and estradiol all considerably altered this decline, but the lowest dose of genistein had a stronger impact than the other two therapies. Furthermore, the best genistein dosage for enhancing wound tensile strength and skin healing was the lowest one. Inferences and conclusions: One potential alternative treatment for the control of skin wound healing is genistein aglycone.","PeriodicalId":512642,"journal":{"name":"Journal of Dermatology Research","volume":" 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139620024","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0