Developmental Neurorehabilitation最新文献

筛选
英文 中文
Exploring Clinical and Neurophysiological Factors Associated with Response to Constraint Therapy and Brain Stimulation in Children with Hemiparetic Cerebral Palsy. 探讨与偏瘫性脑瘫患儿约束治疗和脑刺激反应相关的临床和神经生理因素。
IF 1.3 4区 医学
Developmental Neurorehabilitation Pub Date : 2022-05-01 Epub Date: 2021-08-14 DOI: 10.1080/17518423.2021.1964103
Hsing-Ching Kuo, Jennifer Litzenberger, Alberto Nettel-Aguirre, Ephrem Zewdie, Adam Kirton
{"title":"Exploring Clinical and Neurophysiological Factors Associated with Response to Constraint Therapy and Brain Stimulation in Children with Hemiparetic Cerebral Palsy.","authors":"Hsing-Ching Kuo,&nbsp;Jennifer Litzenberger,&nbsp;Alberto Nettel-Aguirre,&nbsp;Ephrem Zewdie,&nbsp;Adam Kirton","doi":"10.1080/17518423.2021.1964103","DOIUrl":"https://doi.org/10.1080/17518423.2021.1964103","url":null,"abstract":"<p><strong>Background: </strong>Perinatal stroke causes hemiparetic cerebral palsy (HCP) and lifelong disability. Constraint-induced movement therapy (CIMT) and neurostimulation may enhance motor function, but the individual factors associated with responsiveness are undetermined.</p><p><strong>Objective: </strong>We explored the clinical and neurophysiological factors associated with responsiveness to CIMT and/or brain stimulation within a clinical trial.</p><p><strong>Methods: </strong>PLASTIC CHAMPS was a randomized, blinded, sham-controlled trial (n = 45) of CIMT and neurostimulation paired with intensive, goal-directed therapy. Primary outcome was the Assisting Hand Assessment (AHA). Classification trees created through recursive partitioning suggested clinical and neurophysiological profiles associated with improvement at 6-months.</p><p><strong>Results: </strong>Both clinical (stroke side (left) and age >14 years) and neurophysiological (intracortical inhibition/facilitation and motor threshold) were associated with responsiveness across treatment groups with positive predictive values (PPV) approaching 80%.</p><p><strong>Conclusion: </strong>This preliminary analysis suggested sets of variables that may be associated with response to intensive therapies in HCP. Further modeling in larger trials is required.</p>","PeriodicalId":51227,"journal":{"name":"Developmental Neurorehabilitation","volume":null,"pages":null},"PeriodicalIF":1.3,"publicationDate":"2022-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39322973","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Process Evaluation of Home-based Bimanual Training in Children with Unilateral Cerebral Palsy (The COAD-study): A Mixed Methods Study. 单侧脑瘫儿童家庭双手训练的过程评价(coad研究):一项混合方法研究。
IF 1.3 4区 医学
Developmental Neurorehabilitation Pub Date : 2022-05-01 Epub Date: 2021-12-26 DOI: 10.1080/17518423.2021.2011459
Lwme Beckers, Rjem Smeets, Mac de Mooij, B Piškur, Jjw van der Burg, Eaa Rameckers, Pbm Aarts, Coad Author Group, Yjm Janssen-Potten
{"title":"Process Evaluation of Home-based Bimanual Training in Children with Unilateral Cerebral Palsy (The COAD-study): A Mixed Methods Study.","authors":"Lwme Beckers,&nbsp;Rjem Smeets,&nbsp;Mac de Mooij,&nbsp;B Piškur,&nbsp;Jjw van der Burg,&nbsp;Eaa Rameckers,&nbsp;Pbm Aarts,&nbsp;Coad Author Group,&nbsp;Yjm Janssen-Potten","doi":"10.1080/17518423.2021.2011459","DOIUrl":"https://doi.org/10.1080/17518423.2021.2011459","url":null,"abstract":"<p><strong>Purpose: </strong>To evaluate the processes and factors that influenced implementation and impact of a home-based bimanual training program in children with unilateral cerebral palsy aged 2 through 7 years.</p><p><strong>Methods: </strong>The program encompassed bimanual task-specific training (3.5 hours/week for 12 weeks) adopting either implicit or explicit motor learning. A therapist and remedial educationalist coached parents. This mixed methods study included course attendance monitoring, questionnaires, registration form, video analysis, interviews, focus group discussion, and drop-out monitoring.</p><p><strong>Results: </strong>Fourteen families participated. The program was not fully implemented as intended. Parents positively experienced the training and were well able to provide it. The program was demanding for the children and time-consuming for parents. Several components positively contributed to the program: task-analysis, instructional videos, and coaching by a therapist and remedial educationalist. Several modifications to the program were proposed.</p><p><strong>Conclusion: </strong>Home-based bimanual training forms a demanding but promising therapeutic approach with potential for optimization.</p>","PeriodicalId":51227,"journal":{"name":"Developmental Neurorehabilitation","volume":null,"pages":null},"PeriodicalIF":1.3,"publicationDate":"2022-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39624434","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
Effect of upper extremity constraints on functional and dynamic postural control in children with hemiplegic cerebral palsy. 上肢约束对偏瘫性脑瘫儿童功能和动态姿势控制的影响。
IF 1.3 4区 医学
Developmental Neurorehabilitation Pub Date : 2022-05-01 Epub Date: 2021-12-31 DOI: 10.1080/17518423.2021.2020351
Meysam Roostaei, Parvin Raji, Khosro Khademi Kalantari, Elham Faghihzadeh, Maria Fragala-Pinkham
{"title":"Effect of upper extremity constraints on functional and dynamic postural control in children with hemiplegic cerebral palsy.","authors":"Meysam Roostaei,&nbsp;Parvin Raji,&nbsp;Khosro Khademi Kalantari,&nbsp;Elham Faghihzadeh,&nbsp;Maria Fragala-Pinkham","doi":"10.1080/17518423.2021.2020351","DOIUrl":"https://doi.org/10.1080/17518423.2021.2020351","url":null,"abstract":"<p><strong>Purpose: </strong>To compare the effects of upper extremity constraints on functional and dynamic postural control in children with hemiplegic cerebral palsy.</p><p><strong>Materials and methods: </strong>Twelve children with hemiplegic cerebral palsy and 12 typically developing children ages 5 to 12 years (GMFCS I-II) were evaluated with the Timed Up and Go (TUG) and Biodex Balance System during three upper extremity (UE) conditions: 1) Free UEs (no constraints), 2) Simple UE constraint (unaffected/dominant UE constrained with a sling), and 3) Difficult UE constraint (Simple constraint plus the other UE holding cup of water).</p><p><strong>Results: </strong>The UE condition had significant effects on Overall Stability Index (OSI) (F<sub>(2,44)</sub> = 24.899, <i>p</i> < .001), Medial-Lateral Stability Index (MLSI) (F<sub>(2,44)</sub> = 4.380, <i>p</i> = .018), Anterior-Posterior Stability Index (F<sub>(2,44)</sub> = 6.187, <i>p</i> = .004), and TUG scores (F<sub>(2,44)</sub> = 113.372, <i>p</i> < .001). Group was significant for OSI (F<sub>(1,22)</sub> = 7.906, <i>p</i> = .010), MLSI (F<sub>(1,22)</sub> = 13.113, <i>p</i> = .002), and TUG (F<sub>(1,22)</sub> = 36.282, <i>p</i> < .001).</p><p><strong>Conclusions: </strong>The upper extremity appears to have a role in maintaining functional balance and postural stability in children with hemiplegic cerebral palsy and should be considered during intervention programs.</p>","PeriodicalId":51227,"journal":{"name":"Developmental Neurorehabilitation","volume":null,"pages":null},"PeriodicalIF":1.3,"publicationDate":"2022-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39775231","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
Attention-Deficit/Hyperactivity Disorder Symptoms, Gastrointestinal Symptoms, Sleep Problems, Challenging Behavior, Adaptive Behavior, and Quality of Life in Children and Adolescents with Autism Spectrum Disorder. 自闭症谱系障碍儿童和青少年的注意力缺陷/多动障碍症状、胃肠道症状、睡眠问题、挑战行为、适应行为和生活质量
IF 1.3 4区 医学
Developmental Neurorehabilitation Pub Date : 2022-05-01 Epub Date: 2021-08-08 DOI: 10.1080/17518423.2021.1964005
Geraldine Leader, Emma Dooley, Sally Whelan, Shawn P Gilroy, June L Chen, Autumn Farren Barton, Rory Coyne, Arlene Mannion
{"title":"Attention-Deficit/Hyperactivity Disorder Symptoms, Gastrointestinal Symptoms, Sleep Problems, Challenging Behavior, Adaptive Behavior, and Quality of Life in Children and Adolescents with Autism Spectrum Disorder.","authors":"Geraldine Leader,&nbsp;Emma Dooley,&nbsp;Sally Whelan,&nbsp;Shawn P Gilroy,&nbsp;June L Chen,&nbsp;Autumn Farren Barton,&nbsp;Rory Coyne,&nbsp;Arlene Mannion","doi":"10.1080/17518423.2021.1964005","DOIUrl":"https://doi.org/10.1080/17518423.2021.1964005","url":null,"abstract":"<p><p>This study investigated the relationship between sleep, gastrointestinal symptoms, challenging behavior, adaptive behavior, and quality of life between children and adolescents with autism spectrum disorder (ASD), with and without attention-deficit/hyperactivity disorder (AD/HD) symptoms. Parents of 118 children and adolescents with ASD completed the Conners Early Childhood Rating Scale-Parent Short Form or the Conners 3-Parent Short Form, Children's Sleep Habits Questionnaire, Gastrointestinal Symptom Inventory, Behavior Problems Inventory-Short Form, Pediatric Quality of Life Inventory and the Vineland Adaptive Behavior Scales, Second Edition. The ASD group and the ASD with AD/HD groups differed significantly in sleep problems, gastrointestinal symptoms, and quality of life. Regressions indicated that AD/HD symptoms accounted for a small proportion of the variance for the differences in sleep problems and quality of life. AD/HD symptoms contribute to the complex needs of individuals with ASD. Research is necessary to investigate how these symptoms exacerbate comorbidities.</p>","PeriodicalId":51227,"journal":{"name":"Developmental Neurorehabilitation","volume":null,"pages":null},"PeriodicalIF":1.3,"publicationDate":"2022-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39291866","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 6
A Pilot Study Exploring Social Validity Ratings of Social Profiles for College Students. 一项探索大学生社会档案社会有效性评级的试点研究。
IF 1.3 4区 医学
Developmental Neurorehabilitation Pub Date : 2022-05-01 Epub Date: 2021-12-04 DOI: 10.1080/17518423.2021.2011460
Helena Bush, John T Rapp, Nadrat Nuhu
{"title":"A Pilot Study Exploring Social Validity Ratings of Social Profiles for College Students.","authors":"Helena Bush,&nbsp;John T Rapp,&nbsp;Nadrat Nuhu","doi":"10.1080/17518423.2021.2011460","DOIUrl":"https://doi.org/10.1080/17518423.2021.2011460","url":null,"abstract":"<p><p>Nuhu and Rapp identified three profiles undergraduates displayed during social interactions. We evaluated the social validity of these three profiles in two studies. In Study 1 we presented video exemplars of speakers representing each profile to undergraduate participants and asked them to rate the speaker in respect to various statements. Results showed that one profile was rated significantly different than the other two profiles on all but one statement. In Study 2 we further evaluated the role of eye contact in the profile that participants rated differently in Study 1. Results from Study 2 showed that a speaker engaging in low eye contact was rated lower than a speaker engaging in either a validated or high level of eye contact. Likewise, participants with self-reported high social competency provided more negative ratings of a speaker who displayed low eye contact than participants with self-reported Moderate and Low social competency.</p>","PeriodicalId":51227,"journal":{"name":"Developmental Neurorehabilitation","volume":null,"pages":null},"PeriodicalIF":1.3,"publicationDate":"2022-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39693843","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Comparison of the Upper and Lower Extremity and Trunk Muscle Masses between Children with Down Syndrome and Children with Typical Development. 唐氏综合征患儿与正常发育患儿上肢、下肢及躯干肌肉质量的比较。
IF 1.3 4区 医学
Developmental Neurorehabilitation Pub Date : 2022-05-01 Epub Date: 2021-12-20 DOI: 10.1080/17518423.2021.2018518
Mitsuhiro Masaki, Seina Maruyama, Yukika Inagaki, Yukine Ogawa, Yoshino Sato, Minori Yokota, Moeka Takeuchi, Maki Kasahara, Kota Minakawa, Kana Kato, Kenji Sakaino
{"title":"Comparison of the Upper and Lower Extremity and Trunk Muscle Masses between Children with Down Syndrome and Children with Typical Development.","authors":"Mitsuhiro Masaki,&nbsp;Seina Maruyama,&nbsp;Yukika Inagaki,&nbsp;Yukine Ogawa,&nbsp;Yoshino Sato,&nbsp;Minori Yokota,&nbsp;Moeka Takeuchi,&nbsp;Maki Kasahara,&nbsp;Kota Minakawa,&nbsp;Kana Kato,&nbsp;Kenji Sakaino","doi":"10.1080/17518423.2021.2018518","DOIUrl":"https://doi.org/10.1080/17518423.2021.2018518","url":null,"abstract":"<p><strong>Purpose: </strong>Comparison of not only the upper and lower extremity but also trunk muscle masses measured by means of an ultrasound imaging device between children with Down syndrome (DS) and children with typical development (TD).</p><p><strong>Methods: </strong>The study included 35 children with TD (TD group) and 26 children with DS (DS group). The upper and lower extremity and trunk muscle thicknesses were measured using an ultrasound imaging device.</p><p><strong>Results: </strong>The thicknesses of the rectus abdominis, obliquus externus and internus abdominis, rectus femoris, and short head of the biceps femoris muscles were significantly lower in the DS group than in the TD group. The thicknesses of the other upper and lower extremity and trunk muscles did not differ significantly between the groups.</p><p><strong>Conclusions: </strong>The results of this study demonstrated lower masses of trunk flexor and knee extensor and flexor muscles in children with DS compared to those in children with TD.</p>","PeriodicalId":51227,"journal":{"name":"Developmental Neurorehabilitation","volume":null,"pages":null},"PeriodicalIF":1.3,"publicationDate":"2022-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39829878","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Determinants of Manual Abilities of Children with Cerebral Palsy: A National Registry-Based Study. 脑瘫儿童手工能力的决定因素:一项基于全国登记的研究。
IF 1.3 4区 医学
Developmental Neurorehabilitation Pub Date : 2022-04-01 Epub Date: 2021-04-14 DOI: 10.1080/17518423.2021.1914761
Sana M N Abu-Dahab, Nihad A Almasri, Maysoun Saleh, Somaya H Malkawi
{"title":"Determinants of Manual Abilities of Children with Cerebral Palsy: A National Registry-Based Study.","authors":"Sana M N Abu-Dahab,&nbsp;Nihad A Almasri,&nbsp;Maysoun Saleh,&nbsp;Somaya H Malkawi","doi":"10.1080/17518423.2021.1914761","DOIUrl":"https://doi.org/10.1080/17518423.2021.1914761","url":null,"abstract":"<p><strong>Purpose: </strong>This cross-sectional study aimed to identify determinants of manual abilities of children with cerebral palsy (CP), as measured by the Manual Ability Classification System (MACS), in terms of intrinsic (child-related) and extrinsic (service-related) variables.</p><p><strong>Methods: </strong>The participants were 106 children with a confirmed diagnosis of CP (aged 4-16 years). Two ordinal logistic regression models were conducted to identify intrinsic and extrinsic determinants of manual abilities.</p><p><strong>Results: </strong>Four child-related (intrinsic) variables were found to be significant determinants of manual abilities: bimanual ability, ability to maintain and assume chair sitting, presence of seizures, and gross motor function, and only one service-related (extrinsic) significant variable was identified, which was receiving spasticity medications.</p><p><strong>Discussion: </strong>The results highlight several determinants that should be considered when assessing and intervening to improve manual abilities of children with CP. The findings are discussed in relation to the intervention approach, contextual modification, and assistive device prescription.</p>","PeriodicalId":51227,"journal":{"name":"Developmental Neurorehabilitation","volume":null,"pages":null},"PeriodicalIF":1.3,"publicationDate":"2022-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1080/17518423.2021.1914761","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25599872","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Solution-Focused Coaching to Support Clinicians' Professional Development: An Analysis of Relational Strategies and Co-constructed Outcomes. 以解决方案为中心的指导以支持临床医生的专业发展:关系策略和共同构建结果的分析。
IF 1.3 4区 医学
Developmental Neurorehabilitation Pub Date : 2022-04-01 Epub Date: 2021-12-03 DOI: 10.1080/17518423.2021.2011458
Gillian King, Patricia Baldwin, Michelle Servais, Sheila Moodie
{"title":"Solution-Focused Coaching to Support Clinicians' Professional Development: An Analysis of Relational Strategies and Co-constructed Outcomes.","authors":"Gillian King,&nbsp;Patricia Baldwin,&nbsp;Michelle Servais,&nbsp;Sheila Moodie","doi":"10.1080/17518423.2021.2011458","DOIUrl":"https://doi.org/10.1080/17518423.2021.2011458","url":null,"abstract":"<p><strong>Purpose: </strong>To explore solution-focused coaching (SFC) as a means to enhance pediatric rehabilitation practitioners' development of listening skills.</p><p><strong>Methods: </strong>Six clinicians each participated in two SFC sessions with an experienced coach who used a practice model developed for pediatric rehabilitation (SFC-peds). The transcribed interviews were analyzed by inductive content analysis to identify the coach's use of relational strategies and the nature of what was being co-constructed in the sessions.</p><p><strong>Results: </strong>The coach used six relational strategies (e.g., supporting reflective and critical thinking). Through dialogue and reflection, the coach and clinician co-constructed four important outcomes, including shared meaning, awareness and discovery of strengths and values, discovery of strategies and opportunities, and forward movement.</p><p><strong>Conclusions: </strong>The study informs our understanding of the relational processes and benefits of SFC conversations. These conversations appear to provide an optimal learning space to enhance professional development, by facilitating the co-creation of meaning, awareness, and intentionality.</p>","PeriodicalId":51227,"journal":{"name":"Developmental Neurorehabilitation","volume":null,"pages":null},"PeriodicalIF":1.3,"publicationDate":"2022-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39956509","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
An assistive technology program for enabling five adolescents emerging from a minimally conscious state to engage in communication, occupation, and leisure opportunities. 一个辅助技术项目,使五名青少年从最低意识状态中脱颖而出,从事交流,职业和休闲机会。
IF 1.3 4区 医学
Developmental Neurorehabilitation Pub Date : 2022-04-01 Epub Date: 2021-12-11 DOI: 10.1080/17518423.2021.2011457
Fabrizio Stasolla, Alessandro O Caffò, Sara Bottiroli, Donatella Ciarmoli
{"title":"An assistive technology program for enabling five adolescents emerging from a minimally conscious state to engage in communication, occupation, and leisure opportunities.","authors":"Fabrizio Stasolla,&nbsp;Alessandro O Caffò,&nbsp;Sara Bottiroli,&nbsp;Donatella Ciarmoli","doi":"10.1080/17518423.2021.2011457","DOIUrl":"https://doi.org/10.1080/17518423.2021.2011457","url":null,"abstract":"<p><strong>Background: </strong>Post-coma patients emerging from a minimally conscious state may have extensive motor disabilities and pose serious challenges to medical centers and home settings.</p><p><strong>Objectives: </strong>To promote academic performance and communication skills of post-coma individuals with traumatic brain injuries emerging from a minimally conscious state through an Assistive Technology setup. To evaluate its effects on the participants' positive participation. To generalize the learning process. To assess the intervention's clinical and social validity.</p><p><strong>Method: </strong>Study I included five adolescents exposed to an Assistive Technology setup enabling them with targeted adaptive behaviors. Study II involved fifty external raters in a social validation assessment.</p><p><strong>Results: </strong>Data evidenced an improved performance of all the participants during the intervention, assessed through a concurrent multiple baseline design across participants. Social raters favorably scored the use of the technology.</p><p><strong>Conclusion: </strong>An Assistive Technology setup may be helpful to enhance the performance and positive participation of adolescents with traumatic brain injuries emerging from a minimally conscious state.</p>","PeriodicalId":51227,"journal":{"name":"Developmental Neurorehabilitation","volume":null,"pages":null},"PeriodicalIF":1.3,"publicationDate":"2022-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39828188","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 5
Evaluation and Maintenance of Behavioral Interventions for 22q11.2 Deletion Syndrome. 22q11.2缺失综合征行为干预的评估与维持
IF 1.3 4区 医学
Developmental Neurorehabilitation Pub Date : 2022-04-01 Epub Date: 2021-08-03 DOI: 10.1080/17518423.2021.1960919
Louis Busch, Valdeep Saini, Sidrah Karim, Roland Jones
{"title":"Evaluation and Maintenance of Behavioral Interventions for 22q11.2 Deletion Syndrome.","authors":"Louis Busch,&nbsp;Valdeep Saini,&nbsp;Sidrah Karim,&nbsp;Roland Jones","doi":"10.1080/17518423.2021.1960919","DOIUrl":"https://doi.org/10.1080/17518423.2021.1960919","url":null,"abstract":"<p><p>22q11.2-deletion syndrome is a genetic disorder caused by a small deletion of chromosome 22. This deletion often results in developmental delays, learning disabilities, medical conditions, and comorbid psychiatric conditions. Patients with 22q11.2DS may present with a variety of behavioral phenotypes including obsessiveness and rigidity, poor social skills, and anxiety. In some cases, the phenotype can consist of destructive and inappropriate behavior including harming self and others. Behavioral difficulties are reported as one of the most challenging aspects of 22q11.2-deletion syndrome for families of patients, however, few studies have examined behavioral interventions as a possible therapeutic treatment for this population. Using principles derived from operant-behavioral psychology, we conducted functional assessments to determine the environmental correlates of destructive and inappropriate behaviors in two adult men with 22q11.2-deletion syndrome. Subsequently, behavioral interventions based on differential reinforcement were incorporated into each participant's natural environment to eliminate these behaviors. Significant reductions in destructive and inappropriate behavior were observed with both participants and therapeutic gains were maintained at follow-up. We discuss the role of behavioral interventions in combination with appropriate psychotropic medication when addressing challenging behaviors in this population.</p>","PeriodicalId":51227,"journal":{"name":"Developmental Neurorehabilitation","volume":null,"pages":null},"PeriodicalIF":1.3,"publicationDate":"2022-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39269587","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
相关产品
×
本文献相关产品
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信