Veterinary Quarterly最新文献_第3页

Isatidis root polysaccharides ameliorates post-weaning diarrhea by promoting intestinal health and modulating the gut microbiota in piglets. 伊沙提斯根多糖通过促进仔猪肠道健康和调节肠道微生物群来改善断奶后腹泻。

IF 7.9 2区农林科学

Veterinary Quarterly Pub Date : 2025-12-01 Epub Date: 2025-01-03 DOI: 10.1080/01652176.2024.2447600

Miao Zhou, Zenghao Yan, Deqin Wang, Chuyuan Li, Leli Wang, Rui Li, Jie Yin, Yulong Yin

{"title":"Isatidis root polysaccharides ameliorates post-weaning diarrhea by promoting intestinal health and modulating the gut microbiota in piglets.","authors":"Miao Zhou, Zenghao Yan, Deqin Wang, Chuyuan Li, Leli Wang, Rui Li, Jie Yin, Yulong Yin","doi":"10.1080/01652176.2024.2447600","DOIUrl":"https://doi.org/10.1080/01652176.2024.2447600","url":null,"abstract":"This study aimed to investigate the effects of dietary isatidis root polysaccharide (IRP) on diarrhea, immunity, and intestinal health in weanling piglets. Forty healthy piglets were randomly assigned to five groups receiving varying dosages of IRP. The findings indicated that different concentrations of IRP significantly reduced diarrhea scores (p < 0.01). Notably, the serum levels of immunoglobulin A and immunoglobulin G increased linearly and quadratically (p < 0.01), while immunoglobulin M also showed a linear increase (p < 0.05) in IRP-fed piglets. The secretory immunoglobulin A levels in ileal contents were significantly higher compared to control piglets (p < 0.01). Key intestinal health parameters, including villus height, villus height-to-crypt depth ratio, and goblet cell numbers, showed linear and quadratic increases in both the jejunum and ileum (p < 0.05), while crypt depth decreased significantly (p < 0.01). Additionally, the expression of IL-10, ZO-1, occludin, and mucin2 was upregulated linearly and quadratically in IRP-fed piglets (p < 0.05). In cultured IPEC-J2 cells, ZO-1 and occludin expression levels significantly increased upon exposure to 400 μg/mL IRP (p < 0.01). Furthermore, the relative abundances of Escherichia coli, Ralstonia pickettii, and Desulfovibrio fairfieldensis decreased linearly with increasing dietary IRP concentration. In conclusion, IRP shows promise as an effective dietary supplement for mitigating diarrhea and enhancing intestinal health in early weaned piglets.","PeriodicalId":51207,"journal":{"name":"Veterinary Quarterly","volume":"45 1","pages":"1-15"},"PeriodicalIF":7.9,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142928693","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Large-scale evaluation of bacteriological-based method and qPCR performance for Brucellosis diagnosis in livestock using Bayesian latent class analysis. 利用贝叶斯潜类分析大规模评价基于细菌学的方法和qPCR在家畜布鲁氏菌病诊断中的性能。

IF 7.9 2区农林科学

Veterinary Quarterly Pub Date : 2025-12-01 Epub Date: 2025-06-09 DOI: 10.1080/01652176.2025.2514753

Giovanna Fusco, Alessandro Bellato, Lorena Cardillo, Agata Campione, Michela Di Roberto, Anna Cerrone, Francesca Bove, Roberta Pellicanò, Maria Ottaiano, Marco Esposito, Antonio Limone, Anna Rita Attili, Esterina De Carlo

{"title":"Large-scale evaluation of bacteriological-based method and qPCR performance for Brucellosis diagnosis in livestock using Bayesian latent class analysis.","authors":"Giovanna Fusco, Alessandro Bellato, Lorena Cardillo, Agata Campione, Michela Di Roberto, Anna Cerrone, Francesca Bove, Roberta Pellicanò, Maria Ottaiano, Marco Esposito, Antonio Limone, Anna Rita Attili, Esterina De Carlo","doi":"10.1080/01652176.2025.2514753","DOIUrl":"10.1080/01652176.2025.2514753","url":null,"abstract":"The performance of direct tests, such as bacteriological culture and qPCR, for the diagnosis of brucellosis has been evaluated in a limited number of studies, often based on small sample sizes. Moreover, the absence of a gold standard makes this assessment even more challenging. A potential alternative for evaluating the performance of direct tests is Bayesian latent class analysis (BLCA), which does not require prior knowledge of disease status or a gold standard. This study aimed to estimate the sensitivity (Se) and specificity (Sp) of bacteriological culture for brucellosis diagnosis. In a brucellosis-endemic area, a large number of seronegative and seropositive buffaloes and cattle were tested using bacteriological culture and qPCR. BLCA was applied to estimate the performance of both tests. The median Se of bacteriological culture was estimated at 61.3%, compared to 70.9% of qPCR. The median Sp was 99.6% for bacteriological culture and 89.3% for qPCR. Bacteriological culture demonstrated a higher Positive Predictive Value (PPV) than qPCR in both buffaloes and cattle, whereas the Negative Predictive Value (NPV) of the two methods did not differ significantly. These results suggest that, in settings of low brucellosis prevalence, a positive bacteriological culture has a greater predictive value than qPCR .","PeriodicalId":51207,"journal":{"name":"Veterinary Quarterly","volume":"45 1","pages":"1-10"},"PeriodicalIF":7.9,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12150646/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144250772","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Neutralizing antibody levels as a key factor in determining the immunogenic efficacy of the novel PEDV alpha coronavirus vaccine. 中和抗体水平是决定新型PEDV α冠状病毒疫苗免疫原性效果的关键因素

IF 7.9 2区农林科学

Veterinary Quarterly Pub Date : 2025-12-01 Epub Date: 2025-05-28 DOI: 10.1080/01652176.2025.2509506

Guangli Hu, Xin Luo, Jiamin Liao, Chuangchao Zou, Yihui Huang, Rui Geng, Zhiqing Zhao, Hanqin Shen, Yongchang Cao, Ouyang Peng, Hao Zhang

{"title":"Neutralizing antibody levels as a key factor in determining the immunogenic efficacy of the novel PEDV alpha coronavirus vaccine.","authors":"Guangli Hu, Xin Luo, Jiamin Liao, Chuangchao Zou, Yihui Huang, Rui Geng, Zhiqing Zhao, Hanqin Shen, Yongchang Cao, Ouyang Peng, Hao Zhang","doi":"10.1080/01652176.2025.2509506","DOIUrl":"10.1080/01652176.2025.2509506","url":null,"abstract":"Porcine epidemic diarrhea virus (PEDV) causes significant global agricultural losses. Despite commercial inactivated and live attenuated vaccines, persistent outbreaks underscore the need for more effective solutions. Here, we isolated a novel Chinese PEDV variant, PEDV ShXXY2-2023, with amino acid substitutions in key neutralizing epitopes (N-terminal domain, receptor-binding domain, and CO-26K equivalent epitope) compared to vaccine strains. An inactivated ShXXY2-2023 vaccine induced higher neutralizing antibodies and superior cross-protection versus commercial vaccines. Vaccinated sows conferred enhanced protection to offspring, improving piglet survival post-challenge. Maternal serum neutralizing antibody titers correlated strongly with piglet survival; titers of 1:377-1:774 at one week prepartum yielded >80% protective efficacy. These findings emphasize neutralizing antibodies' critical role in PEDV prevention and position ShXXY2-2023 as a promising vaccine candidate, with broader implications for coronavirus vaccine development.","PeriodicalId":51207,"journal":{"name":"Veterinary Quarterly","volume":"45 1","pages":"1-20"},"PeriodicalIF":7.9,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12120861/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144163344","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Methodological rigour and reporting quality of the literature on wildlife rescue, rehabilitation, and release: a global systematic review. 野生动物救援、康复和释放文献的方法严谨性和报告质量：一项全球系统综述。

IF 5.2 2区农林科学

Veterinary Quarterly Pub Date : 2025-12-01 Epub Date: 2025-04-07 DOI: 10.1080/01652176.2025.2478138

Gloeta N Massie, Louis J Backstrom, Daniel P Holland, Mandy B A Paterson, Richard A Fuller

{"title":"Methodological rigour and reporting quality of the literature on wildlife rescue, rehabilitation, and release: a global systematic review.","authors":"Gloeta N Massie, Louis J Backstrom, Daniel P Holland, Mandy B A Paterson, Richard A Fuller","doi":"10.1080/01652176.2025.2478138","DOIUrl":"10.1080/01652176.2025.2478138","url":null,"abstract":"Wildlife rescue, rehabilitation, and release is a global practice with a broad body of scientific literature; nonetheless, no studies have assessed and quantified the methodological rigour and reporting quality of this literature. In this PRISMA systematic review, we assessed and quantified the reporting of controls, randomisation, blinding, experimental animal data, and housing and husbandry data in 152 primary studies on wildlife rescue, rehabilitation, and release published between 1980 and 2021. We then tested for associations between reporting and study characteristics. Of the 152 reviewed studies, one study reported a control, randomisation, and blinding; 17 studies reported species, age, sex, weight, and body condition; and 14 studies reported housing size, housing location, type of food, provision of water, and provision of enrichment. No study reported all 13 of these elements. Studies published in veterinary-focused journals reported lower methodological rigour and had lower reporting quality than studies published in other types of journals. Studies on mammals had higher reporting quality than studies on birds and on reptiles, and studies that included the word \"welfare\" had higher reporting quality than studies that did not. The overall low methodological rigour and reporting quality of the literature limits study replicability and applicability and impedes meta-analyses.","PeriodicalId":51207,"journal":{"name":"Veterinary Quarterly","volume":"45 1","pages":"1-12"},"PeriodicalIF":5.2,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11980188/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143796397","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Development and immunogenicity of adenoviral Fc-fused FMDV virus-like particle vaccine in swine. 腺病毒fc融合猪口蹄疫病毒样颗粒疫苗的研制及其免疫原性。

IF 5.2 2区农林科学

Veterinary Quarterly Pub Date : 2025-12-01 Epub Date: 2025-09-30 DOI: 10.1080/01652176.2025.2564443

Jae-Yeon Park, Hye-Mi Lee, Ki-Jong Kang, Min Kyo Jung, Ji Young Mun, Moon-Ju Kim, Jae-Cheol Pyun, Seong Yun Hwang, Jong-Hyeon Park, Hyun-Jin Shin

{"title":"Development and immunogenicity of adenoviral Fc-fused FMDV virus-like particle vaccine in swine.","authors":"Jae-Yeon Park, Hye-Mi Lee, Ki-Jong Kang, Min Kyo Jung, Ji Young Mun, Moon-Ju Kim, Jae-Cheol Pyun, Seong Yun Hwang, Jong-Hyeon Park, Hyun-Jin Shin","doi":"10.1080/01652176.2025.2564443","DOIUrl":"10.1080/01652176.2025.2564443","url":null,"abstract":"Foot-and-mouth disease (FMD) remains a major threat to global livestock health, and current inactivated vaccines face limitations in biosafety and cross-protection. Virus-like particle (VLP) -based vaccines offer a safer alternative, however, their production is often hindered by the cytotoxicity of the viral 3C protease. In this study, we developed a modified 3C protease with reduced cytotoxicity, enabling efficient expression of FMDV VLPs via an internal ribosome entry site (IRES)-based system. To enhance immunogenicity, the swine IgG Fc fragment (sFc) was genetically fused to the VLP capsid protein by modifying the VP1-2A region, resulting in successful surface display of sFc on the VLPs. The modified VLPs were then incorporated into a replication-defective adenoviral vector (Ad5), allowing for efficient antigen delivery and presentation. Immunization of swine with the Ad5-FMDV VLP-sFc vaccine elicited robust FMDV-specific IgG and neutralizing antibody responses, along with a balanced Th1/Th2 cytokine profile. These findings suggest that the Ad5-FMDV VLP-sFc construct is a promising FMD vaccine candidate with enhanced safety and immunogenic potential.","PeriodicalId":51207,"journal":{"name":"Veterinary Quarterly","volume":"45 1","pages":"2564443"},"PeriodicalIF":5.2,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12486460/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145193725","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Supplemental glucose oxidase as an antibiotic substitute alleviates diarrhea and improves intestinal health in weaned piglets. 添加葡萄糖氧化酶作为抗生素替代品可减轻断奶仔猪腹泻，改善肠道健康。

IF 7.9 2区农林科学

Veterinary Quarterly Pub Date : 2025-12-01 Epub Date: 2025-01-01 DOI: 10.1080/01652176.2024.2447592

Dan Chen, Jiaming Chen, Zemin Dong, Qingyun Cao, Hui Ye, Dingyuan Feng, Changming Zhang, Jianjun Zuo, Weiwei Wang

{"title":"Supplemental glucose oxidase as an antibiotic substitute alleviates diarrhea and improves intestinal health in weaned piglets.","authors":"Dan Chen, Jiaming Chen, Zemin Dong, Qingyun Cao, Hui Ye, Dingyuan Feng, Changming Zhang, Jianjun Zuo, Weiwei Wang","doi":"10.1080/01652176.2024.2447592","DOIUrl":"https://doi.org/10.1080/01652176.2024.2447592","url":null,"abstract":"Weaning stress-induced diarrhea is a serious issue in pig production. This study aimed to evaluate the potential of glucose oxidase (GOD) as an antibiotic substitute to alleviate diarrhea and improve gut health in weaned piglets. According to a randomized complete block design, 250 piglets weaned around 21 d of age were allocated into 5 groups (5 replicates/group), which received a basal diet without or with supplemental 200 mg/kg antibiotic, 500, 1000 and 2000 U/kg GOD, respectively. Dietary treatments did not affect (p > 0.05) growth performance of piglets. However, supplemental all doses of GOD were equivalent or superior to antibiotic to reduce (p < 0.05) diarrhea as well as increase (p < 0.05) thymus index, hepatic and colonic antioxidant properties. GOD addition at 1000 and 2000 U/kg reduced (p < 0.05) cecal and rectal pH value, respectively. They also displayed similar or superior efficacy to antibiotic in improving (p < 0.05) duodenal and jejunal morphology along with certain tight junction proteins expression of jejunum and colon. Collectively, GOD represents an antibiotic alternative to reduce diarrhea of weaned piglets through associating with ameliorations of intestinal structure and functions.","PeriodicalId":51207,"journal":{"name":"Veterinary Quarterly","volume":"45 1","pages":"1-9"},"PeriodicalIF":7.9,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142916207","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

PCR testing of conjunctival swabs to detect feline leukaemia virus in domestic cats in Thailand. 泰国家猫结膜拭子检测猫白血病病毒的PCR检测。

IF 7.9 2区农林科学

Veterinary Quarterly Pub Date : 2025-12-01 Epub Date: 2025-04-21 DOI: 10.1080/01652176.2025.2488025

Hsu Po Po Aung, Tawewan Issarankura Na Ayudhaya, Kridsada Chaichoun, Jarupha Taowan, Aeknarin Saechin, Supakit Buamas, Ruangrat Buddhirongawatr

{"title":"PCR testing of conjunctival swabs to detect feline leukaemia virus in domestic cats in Thailand.","authors":"Hsu Po Po Aung, Tawewan Issarankura Na Ayudhaya, Kridsada Chaichoun, Jarupha Taowan, Aeknarin Saechin, Supakit Buamas, Ruangrat Buddhirongawatr","doi":"10.1080/01652176.2025.2488025","DOIUrl":"https://doi.org/10.1080/01652176.2025.2488025","url":null,"abstract":"This study aimed to classify the Feline leukaemia virus (FeLV) infection outcomes in domestic cats in Thailand and determine the accuracy of conjunctival swabs for FeLV proviral DNA detection by comparing results to PCR testing of blood samples. Whole blood and conjunctival swabs were collected from 126 cats with and without clinical signs. Blood specimens were evaluated for p27 FeLV antigen using the SNAP Feline Immunodeficiency Virus (FIV)/FeLV Combo Test, IDEXX Laboratories. The 3'-LTR region of the proviral FeLV was amplified from both blood and conjunctival samples. The prevalence rates of progressive and regressive FeLV infections in this study were 14.3% (95% CI: 8.69-21.63) and 36.5% (95% CI: 28.12-45.55), respectively. Cats older than 12 months of age had a higher probability of being regressively infected than cats younger than 1 year (p-value = 0.039, OR =0.294, 95% CI: 0.092-0.942). Conjunctival swabs used for detecting FeLV proviral DNA demonstrated a sensitivity of 95.3% (95% CI: 86.91-99.02) and a specificity of 100% (95% CI: 94.22-100.00) compared to conventional blood samples. The observed kappa value of 0.956 indicates that conjunctival swabs are reliable and can be used as an alternative to blood venipuncture.","PeriodicalId":51207,"journal":{"name":"Veterinary Quarterly","volume":"45 1","pages":"1-9"},"PeriodicalIF":7.9,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12051441/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144025487","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Phylogenetic network of infectious bronchitis virus: exploring the impact of migratory birds on viral clustering, evolution, and recombination. 传染性支气管炎病毒的系统发育网络：探索候鸟对病毒聚集、进化和重组的影响。

IF 7.9 2区农林科学

Veterinary Quarterly Pub Date : 2025-12-01 Epub Date: 2025-02-14 DOI: 10.1080/01652176.2025.2465570

Yu-Chen Tai, Geng-Ming Hu, Chi-Ming Chen

{"title":"Phylogenetic network of infectious bronchitis virus: exploring the impact of migratory birds on viral clustering, evolution, and recombination.","authors":"Yu-Chen Tai, Geng-Ming Hu, Chi-Ming Chen","doi":"10.1080/01652176.2025.2465570","DOIUrl":"10.1080/01652176.2025.2465570","url":null,"abstract":"Infectious bronchitis virus (IBV) presents a major threat to global poultry production, necessitating a thorough understanding of its evolutionary relationships for effective control measures. This study presents a novel distance-based Minimum Span Clustering (MSClustering) method to cluster 311 IBV strains, with a comparison of its results to the established IBV classification. Phylogenetic network and recombination analyses were employed to investigate IBV evolutionary relationships and transmission pathways. The phylogenetic network revealed distinct clusters reflecting relationships between IBV strains. Importantly, these network patterns, combined with recombination event analysis, suggest an unrecognized role for migratory birds in IBV dissemination, highlighting potential transmission pathways beyond established poultry trade routes. These findings contribute to advancing our understanding of IBV evolution and support the development of targeted strategies for controlling viral outbreaks in poultry populations. While statistical limitations may affect threshold estimation for smaller networks, our MSClustering method significantly accelerates processing speeds-approximately 100,000 times faster than PhyML when analyzing the dataset-enabling comprehensive-scale phylogenetic analysis of viruses.","PeriodicalId":51207,"journal":{"name":"Veterinary Quarterly","volume":"45 1","pages":"1-14"},"PeriodicalIF":7.9,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11834806/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143415504","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effect of paratuberculosis vaccination before and after oral experimental infection with Mycobacterium avium subspecies paratuberculosis in goats. 山羊口服实验禽分枝杆菌亚种副结核感染前后接种副结核疫苗的效果。

IF 5.2 2区农林科学

Veterinary Quarterly Pub Date : 2025-12-01 Epub Date: 2025-10-01 DOI: 10.1080/01652176.2025.2566363

Marcos Royo, Natalia Elguezábal, Rakel Arrazuria, Julio Benavides, Miguel Fernández

{"title":"Effect of paratuberculosis vaccination before and after oral experimental infection with Mycobacterium avium subspecies paratuberculosis in goats.","authors":"Marcos Royo, Natalia Elguezábal, Rakel Arrazuria, Julio Benavides, Miguel Fernández","doi":"10.1080/01652176.2025.2566363","DOIUrl":"10.1080/01652176.2025.2566363","url":null,"abstract":"Vaccination against paratuberculosis, before or after infection with Mycobacterium avium subsp. paratuberculosis (Map), could affect the progression of paratuberculosis, the development of lesions, the peripheral and local immune response, or the colonization of Map in tissues and its elimination through feces. An experimental study was conducted with thirty-five 1.5-month-old kids, which were separated into 6 experimental groups that include different intervention combinations (vaccinated, non-vaccinated, challenged and non-challenged) at different points and slaughtered at 120 and 330 days post-infection. The use of an inactivated vaccine against paratuberculosis could avoid clinical disease manifestation but does not prevent the tissue colonization, even when applied before Map exposure, achieving a reduction in the presence of viable bacteria in tissues and limiting the progression toward diffuse lesions. The therapeutic effect in vaccinated animals could not be confirmed. In this sense, vaccination not only modulates the immune response in terms of the production of IFN-γ and antibodies in peripheral blood and reduces tissue damage but also contributes to limiting the spread of infection through reduced bacterial shedding especially in goats vaccinated before Map infection.","PeriodicalId":51207,"journal":{"name":"Veterinary Quarterly","volume":"45 1","pages":"2566363"},"PeriodicalIF":5.2,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12490372/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145202064","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Validation of a new textile sensor band for on-farm heart rate variability assessment in calves. 一种用于小牛农场心率变异性评估的新型纺织传感器带的验证。

IF 5.2 2区农林科学

Veterinary Quarterly Pub Date : 2025-12-01 Epub Date: 2025-10-04 DOI: 10.1080/01652176.2025.2569550

Luca Turini, Gaia Pesenti Rossi, Giulia Sala, Giulia Foggi, Giulia Gislon, Sara Mondini, Sara Barbieri, Sara Calonaci, Elisabetta Canali, Francesca Bonelli, Marcello Mele

{"title":"Validation of a new textile sensor band for on-farm heart rate variability assessment in calves.","authors":"Luca Turini, Gaia Pesenti Rossi, Giulia Sala, Giulia Foggi, Giulia Gislon, Sara Mondini, Sara Barbieri, Sara Calonaci, Elisabetta Canali, Francesca Bonelli, Marcello Mele","doi":"10.1080/01652176.2025.2569550","DOIUrl":"10.1080/01652176.2025.2569550","url":null,"abstract":"Heart rate variability (HRV) has been studied as an indicator of stress and welfare in various species, including dairy calves, where significant changes in HRV were linked to cow-calf separation, isolation and disbudding. Wearable bands with smart textiles biotechnology offer a promising, low-stress alternative due to their comfort and ease of use without shaving or taping. The aim of this study was to examine if smart textiles biotechnology could be compared to a Standard base-apex ECG for measuring HRV in dairy calves. Twenty healthy Italian Holstein calves aged (20-60 days old) were recruited. Standard base-apex ECG and Smartex ECG were simultaneously acquired for 16 min in the standing, unsedated, unclipped calves. After extracting HRV parameters, comparisons were made using time, frequency, and nonlinear analyses. Agreement between devices was assessed using the Bland-Altman test and Spearman's 𝜚 correlations. Sperman's 𝜚 showed a very strong correlation for Mean RR, SDNN and LF (p value < .001), and a strong correlation for RMSSD, LF/HF and SampEn, indicating the most stable relationship between the two systems. Smart textiles biotechnology can be used for HRV measurement in calves, offering a valuable tool for animal welfare assessment.","PeriodicalId":51207,"journal":{"name":"Veterinary Quarterly","volume":"45 1","pages":"2569550"},"PeriodicalIF":5.2,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12498378/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145226388","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0