Veterinary Quarterly最新文献

{"title":"Raman spectral band imaging for the diagnostics and classification of canine and feline cutaneous tumors.","authors":"Mindaugas Tamošiūnas, Martynas Maciulevičius, Romans Maļiks, Diāna Dupļevska, Daira Viškere, Ilze Matīse-van Houtana, Roberts Kadiķis, Blaž Cugmas, Renaldas Raišutis","doi":"10.1080/01652176.2025.2486771","DOIUrl":"https://doi.org/10.1080/01652176.2025.2486771","url":null,"abstract":"<p><p>This study introduces Raman imaging technique for diagnosing skin cancer in veterinary oncology patients (dogs and cats). Initially, Raman spectral bands (with specificity to certain molecular structures and functional groups) were identified in formalin-fixed samples of mast cell tumors and soft tissue sarcomas, obtained through routine veterinary biopsy submissions. Then, a custom-built Raman macro-imaging system featuring an intensified CCD camera (iXon Ultra 888, Andor, UK), tunable narrow-band Semrock (USA) optical filter compartment was used to map the spectral features at 1437 cm^-1 and 1655 cm^-1 in <i>ex vivo</i> tissue. This approach enabled wide-field (cm²), rapid (within seconds), and safe (< 400 mW/cm²) imaging conditions, supporting accurate diagnosis of tissue state. The findings indicate that machine learning classifiers - particularly support vector machine (SVM) and decision tree (DT) - effectively distinguished between soft tissue sarcoma, mastocytoma and benign tissues using Raman spectral band imaging data. Additionally, combining Raman macro-imaging with residual near-infrared (NIR) autofluorescence as a bimodal imaging technique enhanced diagnostic performance, reaching 85 - 95% in accuracy, sensitivity, specificity, and precision - even with a single spectral band (1437 cm^-1 or 1655 cm^-1). In conclusion, the proposed bi-modal imaging is a pioneering method for veterinary oncology science, offering to improve the diagnostic accuracy of malignant tumors.</p>","PeriodicalId":51207,"journal":{"name":"Veterinary Quarterly","volume":"45 1","pages":"1-17"},"PeriodicalIF":7.9,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143812669","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Exploring the interplay between <i>Eimeria</i> spp. infection and the host: understanding the dynamics of gut barrier function.","authors":"Pan Chen, Mujeeb Ur Rehman, Yanfeng He, Aoyun Li, Fuchun Jian, Longxian Zhang, Shucheng Huang","doi":"10.1080/01652176.2025.2452169","DOIUrl":"10.1080/01652176.2025.2452169","url":null,"abstract":"<p><p>Coccidiosis is a global disease caused by protozoans, typically including <i>Eimeria</i> spp., which pose a significant threat to the normal growth and development of young animals. Coccidiosis affects mainly the gut, where parasite proliferation occurs. The intestinal barrier, which consists of chemical, mechanical, biological, and immune defences, plays a crucial role in protecting the host against pathogens, xenobiotics, and toxins present in the gastrointestinal tract. When animals ingest sporulated <i>Eimeria</i> spp. oocysts, these parasites primarily reproduce in the intestinal tract, causing damage to the structure and function of the intestine. This disruption of intestinal homeostasis adversely affects animal health. Numerous studies have also revealed that <i>Eimeria</i>-infected animals experience slower bone growth rates, inferior meat quality, reduced egg production and quality, as well as impaired growth and development. Therefore, the purpose of this review is to examine the underlying mechanisms through which <i>Eimeria</i> spp. regulate intestinal damage and disturb the balance of the internal environment. Specifically, this review will focus on their effects on the structural basis of the host intestine's chemical, mechanical, biological and immune barriers. This understanding is crucial for the development of effective drugs to prevent the invasion of <i>Eimeria</i> spp. into the intestine, which is of paramount importance for maintaining host health.</p>","PeriodicalId":51207,"journal":{"name":"Veterinary Quarterly","volume":"45 1","pages":"1-22"},"PeriodicalIF":7.9,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11749151/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143015461","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical evaluation of HuDo-CSPG4 DNA electroporation as adjuvant treatment for canine oral malignant melanoma: comparison of two vaccination protocols.","authors":"Mariateresa Camerino, Davide Giacobino, Lidia Tarone, Alfredo Dentini, Marina Martano, Emanuela Morello, Erica Ilaria Ferraris, Luca Manassero, Selina Iussich, Lorella Maniscalco, Federica Cavallo, Federica Riccardo, Paolo Buracco","doi":"10.1080/01652176.2025.2473717","DOIUrl":"10.1080/01652176.2025.2473717","url":null,"abstract":"<p><p>Canine oral malignant melanoma (OMM) is an aggressive, spontaneously occurring tumor carrying a poor to guarded prognosis and relatively limited therapeutic strategies. In this landscape, chondroitin sulfate proteoglycan (CSPG)4 represents a promising immunotherapeutic target. The objective of this bi-center prospective study was to examine the clinical outcome of OMM-bearing dogs treated with surgery and adjuvant electroporation using a DNA vaccine (HuDo-CSPG4) encoding both human (Hu) and canine (Do) portions of CSPG4 through two different vaccination protocols. Dogs with stage I-III surgically resected CSPG4-positive OMM underwent HuDo-CSPG4 plasmid electroporation starting at the 3^rd-4^th post-operative week; electrovaccination was repeated after 2 weeks. In protocol 1, electrovaccination was then delivered monthly while in protocol 2, electrovaccination was performed monthly four additional times followed by semestral boosters. The survival rates of HuDo-CSPG4-vaccinated dogs were estimated and compared with a control group treated with surgery alone. Significantly longer overall survival times were observed in HuDo-CSPG4 vaccinated dogs as compared with non-vaccinated controls. Dogs receiving protocol 2 showed similar outcomes to those of dogs undergoing protocol 1, despite fewer vaccinations. The comparable humoral response against CSPG4 resulting from the administration of protocol 1 and 2 appears to have similar clinical relevance, highlighting protocol 2 as the optimal vaccination schedule.</p>","PeriodicalId":51207,"journal":{"name":"Veterinary Quarterly","volume":"45 1","pages":"1-16"},"PeriodicalIF":7.9,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11894750/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143587724","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"First assessment of the prevalence of <i>Trichinella</i> in backyard-raised pigs in Central-Southern Chile.","authors":"Javiera Guzmán-Faúndez, Vanesa Crisóstomo-Jorquera, Carlos Landaeta-Aqueveque, AnaLía Henríquez","doi":"10.1080/01652176.2025.2475986","DOIUrl":"10.1080/01652176.2025.2475986","url":null,"abstract":"<p><p>Trichinellosis is a significant zoonotic disease worldwide, with pigs as a primary reservoir host of human infection. Backyard pigs are particularly at risk due to their exposure to muscle tissue containing <i>Trichinella</i> larvae from synanthropic micromammals or home slaughter waste. In Chile, veterinary inspections of domestically slaughtered pigs are mainly conducted in veterinary clinics using muscle samples provided by farmers or consumers. While positive cases must be reported to the authorities, negative cases are not, creating a gap in official data on <i>Trichinella</i> prevalence. This study aimed to assess the prevalence of <i>Trichinella</i> sp. in backyard and intensively raised pigs in south-central Chile. Records of 2,608 backyard pigs were obtained from various veterinary clinics in the La Araucanía and Ñuble regions, with a few records from the El Maule and Biobío regions, encompassing a total of 33 communes. The overall prevalence was found to be 0.9% (95% confidence interval: 0.59-1.37). According to the available information, records of more than 50,000 pigs slaughtered in abattoirs per year corresponded to negative results after examination. Previous reports suggest that eradication is challenging; however, the decreasing incidence rate of human infection indicates the possibility of improving control measures for this zoonosis.</p>","PeriodicalId":51207,"journal":{"name":"Veterinary Quarterly","volume":"45 1","pages":"1-7"},"PeriodicalIF":7.9,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11912294/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143617345","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Molecular identification and biological characterization of <i>Eimeria columbarum</i> from domestic pigeons (<i>Columba livia domestica</i>) in Guangdong, China.","authors":"Xi He, Xue-Mei Fang, Yu-Tong Qiao, Jia-Li Su, Sheng-Qiu Tang, Ya-Biao Weng, Rui-Qing Lin","doi":"10.1080/01652176.2024.2412297","DOIUrl":"https://doi.org/10.1080/01652176.2024.2412297","url":null,"abstract":"<p><p>Pigeon coccidiosis caused by <i>Eimeria</i> spp. is an important veterinary disease with a significant economic impact on the pigeon industry. Preventive measures for <i>Eimeria columbarum</i> in pigeons have been hampered by the lack of extensive genetic, morphological, and biological data on the oocysts. In this study, we examined the prevalence and identity of <i>Eimeria</i> spp. in domestic pigeons from seven cities in Guangdong Province, China. Data show that coccidiosis was prevalent in domestic pigeons in Guangdong Province, with an overall <i>Eimeria</i> spp. detection rate of 73.4%. Five <i>Eimeria</i> species were identified, including <i>E. columbarum</i> (73.4%), <i>Eimeria kapotei</i> (25.6%), <i>Eimeria labbeana</i> (19.6%), <i>Eimeria duculai</i> (19.6%), and <i>Eimeria tropicalis</i> (6.7%). We obtained single oocyst-derived lines of the dominant <i>E. columbarum</i> from fecal specimens. <i>E. columbarum</i> oocysts measured 20.06 ± 0.69 μm × 18.63 ± 1.03 μm, and sporocysts measured 10.29 ± 0.82 μm × 85.38 ± 0.46 μm. In infection experiment using obtained <i>E. columbarum</i> isolates, 60-day-old coccidia-free pigeons exhibited a prepatent period of 105 h and patent period of 9-10 days followed by severe diarrhea, depression, anorexia, and emaciation. Endogenous development of the parasite was observed mainly in the cytoplasm of epithelial cells in the duodenum, jejunum, ileum, and rectum. Two generations of meronts developed on days 3 and 4 after infection, respectively, while gamont and gamete developed on day 5 after infection. The morphological, genetic, and biological data are expected to be useful in elucidating the biological characterization of pigeon coccidiosis to develop measures against the treatment and containment of this disease.</p>","PeriodicalId":51207,"journal":{"name":"Veterinary Quarterly","volume":"44 1","pages":"1-11"},"PeriodicalIF":7.9,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11486315/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142480145","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of chronic stress status and quality of life in cats suffering from chronic kidney disease and suspected feline infectious peritonitis based on hair cortisol concentration analysis and a questionnaire.","authors":"Chien-Hui Chen, Chao-Chin Chang, Wei-Che Chen, Ya-Jane Lee","doi":"10.1080/01652176.2024.2379327","DOIUrl":"10.1080/01652176.2024.2379327","url":null,"abstract":"<p><p>Hair cortisol concentration (HCC) and a questionnaire were used as indicators of chronic stress status and quality of life (QoL), respectively, in cats. To date, there has been limited research on the simultaneous application of both indicators in unwell cats. Our aim was to evaluate HCC and questionnaire data obtained from a healthy cat cohort (<i>n</i> = 61) and cat cohorts with either chronic kidney disease (CKD) (<i>n</i> = 78) or suspected feline infectious peritonitis (FIP) (<i>n</i> = 24). Furthermore, we also investigated the correlation between HCC and clinical pathological data. For this study, hair from the abdomen of cats was collected and analyzed for HCC using a commercial ELISA kit. Owners also completed a questionnaire, from which average-item-weighted-impact-scores (AWISs) were calculated. Cats with late-stage-CKD (median, HCC = 330.15 pg/mg, AWIS = -0.43) presented with a significantly higher HCC (<i>p</i> < 0.01) and a significantly lower AWIS (<i>p</i> < 0.01) than cats with early-stage-CKD (HCC = 183.56 pg/mg, AWIS = 1.08). Similarly, there were significant differences in both HCC (<i>p</i> < 0.001) and AWIS (<i>p</i> < 0.001) between cats with suspected FIP (HCC = 896.27 pg/mg, AWIS = -1.97) and healthy cats (HCC = 181.24 pg/mg, AWIS = 1.24). The degree of consistency between the HCC results and the questionnaire results reminds us that the severity of a chronic disease or the presence of a life-threatening disease can significantly increase stress and thus can affect the QoL of cats.</p>","PeriodicalId":51207,"journal":{"name":"Veterinary Quarterly","volume":"44 1","pages":"1-9"},"PeriodicalIF":7.9,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11262211/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141724983","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of the clinical usefulness of pancreatic alpha amylase as a novel biomarker in dogs with acute pancreatitis: a pilot study.","authors":"Keon Kim, Hee-Hong Kim, Jae-Beom Joo, Ock-Kyu Kim, Sin-Wook Park, Guk-Hyun Suh, Woong-Bin Ro, Chang-Min Lee","doi":"10.1080/01652176.2024.2326007","DOIUrl":"10.1080/01652176.2024.2326007","url":null,"abstract":"<p><p>Pancreatic alpha amylase (P-AMY) is used as a biomarker of acute pancreatitis (AP) in human medicine. To our knowledge, there are no studies evaluating the usefulness of P-AMY in dogs with AP. In this study, we evaluated the diagnostic value of P-AMY, currently not verified in veterinary medicine. The AP group (<i>n</i> = 40) consisted of dogs with AP diagnosed using clinical signs and laboratory examinations, including abnormal canine pancreatic lipase (cPL) concentration, and compatible abdominal ultrasound examination at first presentation. Evaluation of the canine AP severity (CAPS) score was performed. The control group (<i>n</i> = 38) was composed of normal dogs without any abnormalities in clinical findings, blood exams or diagnostic imaging. The correlation of P-AMY with cPL was confirmed by Pearson's correlation analysis (<i>r</i> = 0.564, <i>p</i> < .001). The sensitivity and specificity for the most appropriate cut-off values of P-AMY were recorded similar to the values of DGGR. The dogs with AP and CAPS ≥11 had significantly higher serum P-AMY (<i>p</i> = .016) contrary to DGGR lipase and cPL. Furthermore, there was a significant difference in the median P-AMY dependent on the presence of systemic inflammatory response syndrome (<i>p</i> = .001). P-AMY showed similar level of diagnostic accuracy along with sensitivity and specificity compared to DGGR lipase. In addition, P-AMY showed a significant association with CAPS score, contrary to cPL and DGGR lipase. Along with other biomarkers associated with AP, P-AMY has the potential of usefulness as a supportive diagnostic and prognostic biomarker of AP in dogs.</p>","PeriodicalId":51207,"journal":{"name":"Veterinary Quarterly","volume":"44 1","pages":"1-7"},"PeriodicalIF":6.4,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10949834/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140144546","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Live performance, nutrient digestibility, immune response and fecal microbial load modulation in Japanese quails fed a <i>Bacillus</i>-based probiotic alone or combination with xylanase.","authors":"Asad Sultan, Syed Murtaza, Shabana Naz, Ziaul Islam, Abdulwahed Fahad Alrefaei, Rifat Ullah Khan, Samia H Abdelrahman, A Chandrasekaran","doi":"10.1080/01652176.2024.2364641","DOIUrl":"10.1080/01652176.2024.2364641","url":null,"abstract":"<p><p>Animal industry seeks cost-effective solutions to enhance performance and health of domestic animals. This study investigated the effects of supplementing <i>Bacillus</i> spp. probiotics and xylanase on 2000 one-day-old Japanese quails, randomly assigned to four treatment groups (10 replicates). The control group received no supplementation, while the others were supplemented with a <i>Bacillus</i>-based probiotic at 7.5 × 10⁷ cfu/kg of feed, xylanase enzyme (2,000 U/kg) alone or in combination. Quails receiving both probiotic and enzyme exhibited significantly (<i>p</i> < 0.01) higher weekly and overall weight gain, and lower feed conversion ratios compared to the control group. Dressing percentage was higher (<i>p</i> < 0.01), and mortality lower in birds supplemented with a combination of enzyme and probiotic. Antibody titres against infectious bronchitis and infectious bursal disease were significantly (<i>p</i> < 0.01) higher in quails receiving combined probiotic and enzyme supplementation, while titres against Newcastle disease virus were higher (<i>p</i> < 0.01) in groups supplemented with probiotic and enzyme individually or in combination. Additionally, digestibility was significantly (<i>p</i> < 0.01) higher in groups receiving combined enzyme and probiotic supplementation, with higher apparent metabolizable energy compared to the control. The populations of beneficial <i>Lactobacillus</i> increased, while harmful <i>E. coli</i> and <i>Salmonella</i> decreased significantly in quails supplemented with both probiotic and enzyme. In conclusion, supplementing xylanase enzyme and probiotic together in Japanese quails positively influenced growth, nutrient digestibility, immune response, and cecal microbiota.</p>","PeriodicalId":51207,"journal":{"name":"Veterinary Quarterly","volume":"44 1","pages":"1-9"},"PeriodicalIF":7.9,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11195456/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141433305","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Diet supplementation with hemp (<i>Cannabis sativa L.</i>) inflorescences: effects on quanti-qualitative milk yield and fatty acid profile on grazing dairy goats.","authors":"Ruggero Amato, Marianna Oteri, Biagina Chiofalo, Fabio Zicarelli, Nadia Musco, Fiorella Sarubbi, Severina Pacifico, Marialuisa Formato, Pietro Lombardi, Federica Di Bennardo, Piera Iommelli, Federico Infascelli, Raffaella Tudisco","doi":"10.1080/01652176.2024.2388715","DOIUrl":"10.1080/01652176.2024.2388715","url":null,"abstract":"<p><p>Hemp (<i>Cannabis sativa L</i>.) is an annual plant belonging to the family of Cannabaceae with several varieties characterized by different fatty acid profile, content in flavonoids, polyphenols, and cannabinoid compounds. Hemp is mostly used in livestock nutrition as oil or as protein cake, but not as inflorescences. The aim of this study was to evaluate the effect of dietary hemp inflorescences on milk yield and composition in grazing dairy goats. Twenty Camosciata delle Alpi goats at their 3rd parity and with a mean body weight of 45.2 ± 2.0 kg, immediately after kidding, were equally allocated into two groups (G: Grazing and GH: grazing and hemp). For three months, all goats were fed on a permanent pasture and received 700/head/day of concentrate; diet of group GH was supplemented with 20 g/head/day of hemp inflorescences. Goats' body weight did not change during the trial. Individual milk yield was daily recorded and samples collected every 20 days for chemical composition and fatty acid profile analysis. No significant differences were found for milk yield and chemical composition. Caproic (C6:0) (1.80 <i>vs.</i> 1.74%; <i>p</i> < 0.01) and lauric acids (C12:0) were significantly higher in milk of group GH (4.83 <i>vs.</i> 4.32%; <i>p</i> < 0.01) as well as linoleic (C18:2) (2.04 <i>vs.</i> 1.93%; <i>p</i> < 0.05), adrenic acid (C22:4) (0.046 <i>vs.</i> 0.031%, <i>p</i> < 0.05), omega-6/omega-3 ratio (3.17 <i>vs.</i> 2.93, <i>p</i> < 0.05) and total conjugated linoleic acids (CLAs) (0.435 <i>vs.</i> 0.417%; <i>p</i> < 0.01). The results of this study suggest that the supplementation of grazing goats' diet with hemp inflorescences may enhance the milk nutritional characteristics by increasing its content of CLAs and other beneficial fatty acids.</p>","PeriodicalId":51207,"journal":{"name":"Veterinary Quarterly","volume":"44 1","pages":"1-8"},"PeriodicalIF":7.9,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11318486/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141908219","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A meta-analysis of livestock brucellosis prevalence in Indonesia.","authors":"Muhammad Rosyid Ridlo, Morsid Andityas, Roza Azizah Primatika, Handang Widantara, Shih Keng Loong, Dian Meididewi Nuraini","doi":"10.1080/01652176.2024.2390945","DOIUrl":"10.1080/01652176.2024.2390945","url":null,"abstract":"<p><p>Indonesia has a long history of livestock brucellosis, but the overall pooled prevalence remains unclear. This study aims to determine the pooled estimated prevalence of livestock brucellosis in Indonesia using the Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA) guidelines. Five databases were searched and screened using predefined inclusion and exclusion criteria. Data from included studies were extracted and analyzed using a random effects model in R 4.3.0 for pooled estimated prevalence, subgroup meta-analysis, and meta-regression. Publication bias and sensitivity tests were conducted using Egger's test, funnel plot, trim and fill plot, and leave-one-out. The screening process identified 46 included studies, representing 47,057 samples for brucellosis testing. The pooled estimated prevalence for livestock brucellosis was 3.25% (95% CI, 1.81%-5.78%) with high heterogeneity (<i>Q</i> = 2130.91, <i>p</i> = 0, <i>I²</i>=98%). Subgroup meta-analysis indicated no significant difference in the prevalence of livestock brucellosis across the main islands in Indonesia (<i>p</i> = 0.44) and across provinces in Sulawesi Island (<i>p</i> = 0.83), but significant differences were found among provinces in Java (<i>p</i> < 0.01). The subgroup meta-analysis based on animal type showed no significant difference between cattle, small ruminants, and pig brucellosis estimated prevalence (<i>p</i> = 0.26). Between serological tests, no significant difference was found (<i>p</i> = 0.77). Meta-regression showed no significant difference in brucellosis prevalence from 1988-2023. Egger's test and funnel plot showed publication bias. Trim and fill test indicated 21 studies should be added. As most studies were conducted in Java and Sulawesi Islands, caution should be exercised in interpreting the results, emphasizing the necessity of increasing the study of brucellosis in other regions.</p>","PeriodicalId":51207,"journal":{"name":"Veterinary Quarterly","volume":"44 1","pages":"1-14"},"PeriodicalIF":7.9,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11338204/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142005796","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}