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Surgical vs transcatheter aortic valve replacement in bicuspid aortic valve stenosis: A systematic review and meta-analysis 手术与经导管主动脉瓣置换术治疗双尖瓣主动脉瓣狭窄：系统回顾和荟萃分析
IF 7.3 2区 医学
Trends in Cardiovascular Medicine Pub Date : 2024-07-01 DOI: 10.1016/j.tcm.2023.04.004
Jimmy JH. Kang , Nicholas M. Fialka , Ryaan EL-Andari , Abeline Watkins , Yongzhe Hong , Anoop Mathew , Sabin J. Bozso , Jeevan Nagendran
{"title":"Surgical vs transcatheter aortic valve replacement in bicuspid aortic valve stenosis: A systematic review and meta-analysis","authors":"Jimmy JH. Kang ,&nbsp;Nicholas M. Fialka ,&nbsp;Ryaan EL-Andari ,&nbsp;Abeline Watkins ,&nbsp;Yongzhe Hong ,&nbsp;Anoop Mathew ,&nbsp;Sabin J. Bozso ,&nbsp;Jeevan Nagendran","doi":"10.1016/j.tcm.2023.04.004","DOIUrl":"10.1016/j.tcm.2023.04.004","url":null,"abstract":"<div><p><span>This systematic review<span><span> and meta-analysis aim to provide a comprehensive analysis of the literature directly comparing the outcomes of surgical aortic valve replacement<span> (SAVR) and TAVR </span></span>in patients<span> with BAV stenosis. Medline, PubMed, and Scopus were systematically searched for articles published between 2000 and 2023, 1862 studies were screened, and 6 retrospective studies met the inclusion criteria. We included 6550 patients in the final analyses: 3,292 and 3,258 in the SAVR and TAVR groups, respectively. Both groups have similar rates of in-hospital mortality (odds ratio (OR) 1.11; 95% CI 0.59–2.10; </span></span></span><em>p</em> = 0.75) and stroke (OR 1.25; 95% CI 0.85–1.86; <em>p</em><span> = 0.26. Patients who underwent SAVR experienced lower rates of permanent pacemaker implantation (OR 0.54; 95% CI 0.35–0.83; </span><em>p</em><span> = 0.005) and paravalvular leak (OR 0.47; 95% CI 0.26–0.86; </span><em>p</em><span> = 0.02). On the other hand, patients who underwent TAVR displayed lower rates of acute kidney injury (OR 1.81; 95% CI 1.15–2.84; </span><em>p</em> = 0.010), major bleeding (OR 3.76; 95% CI 2.18–6.49; <em>p</em> &lt; 0.00001), and pulmonary complications (OR 7.68; 95% CI 1.21–48.84; <em>p</em><span> = 0.03). Despite the early mortality data suggesting that TAVR may be a reasonable strategy for patients with bicuspid AS with low to intermediate surgical risk, the increased risk of PPI and PVL is concerning. A prospective, randomized, controlled trial reporting long-term outcomes with pre-defined subgroup analyses based on BAV morphology is paramount. In the interim, caution should be exercised in the widespread adoption of TAVR in lower surgical-risk patients.</span></p></div>","PeriodicalId":51199,"journal":{"name":"Trends in Cardiovascular Medicine","volume":"34 5","pages":"Pages 304-313"},"PeriodicalIF":7.3,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9896410","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Editorial commentary: Chronic kidney disease and aortic valve replacement: Let's filter the evidence! 编辑评论：慢性肾病与主动脉瓣置换术：让我们过滤证据！
IF 7.3 2区 医学
Trends in Cardiovascular Medicine Pub Date : 2024-07-01 DOI: 10.1016/j.tcm.2023.07.001
Matheus Simonato , Danny Dvir , Michael G. Nanna
{"title":"Editorial commentary: Chronic kidney disease and aortic valve replacement: Let's filter the evidence!","authors":"Matheus Simonato ,&nbsp;Danny Dvir ,&nbsp;Michael G. Nanna","doi":"10.1016/j.tcm.2023.07.001","DOIUrl":"10.1016/j.tcm.2023.07.001","url":null,"abstract":"","PeriodicalId":51199,"journal":{"name":"Trends in Cardiovascular Medicine","volume":"34 5","pages":"Pages 325-326"},"PeriodicalIF":7.3,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9950458","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
H_GF 510 E-Alert mo23648 full BW.pdf H_GF 510 E-Alert mo23648 full BW.pdf
IF 7.3 2区 医学
Trends in Cardiovascular Medicine Pub Date : 2024-07-01 DOI: 10.1016/S1050-1738(24)00056-2
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引用次数: 0
Transcatheter aortic valve implantation versus surgical aortic valve replacement in chronic kidney disease: Meta-analysis of reconstructed time-to-event data 慢性肾脏病患者经导管主动脉瓣植入术与手术主动脉瓣置换术的比较：重建时间到事件数据的元分析
IF 7.3 2区 医学
Trends in Cardiovascular Medicine Pub Date : 2024-07-01 DOI: 10.1016/j.tcm.2023.04.006
Xander Jacquemyn , Jef Van den Eynde , Quinten Iwens , Janne Billiau , Habib Jabagi , Derek Serna-Gallegos , Danny Chu , Ibrahim Sultan , Michel Pompeu Sá
{"title":"Transcatheter aortic valve implantation versus surgical aortic valve replacement in chronic kidney disease: Meta-analysis of reconstructed time-to-event data","authors":"Xander Jacquemyn ,&nbsp;Jef Van den Eynde ,&nbsp;Quinten Iwens ,&nbsp;Janne Billiau ,&nbsp;Habib Jabagi ,&nbsp;Derek Serna-Gallegos ,&nbsp;Danny Chu ,&nbsp;Ibrahim Sultan ,&nbsp;Michel Pompeu Sá","doi":"10.1016/j.tcm.2023.04.006","DOIUrl":"10.1016/j.tcm.2023.04.006","url":null,"abstract":"<div><h3>Background</h3><p><span>Patients with advanced chronic kidney disease (CKD) are a challenging and understudied population. Specifically, the late outcomes following surgical </span>aortic valve replacement<span> (SAVR) or transcatheter aortic valve implantation<span> (TAVI) in patients with CKD remains uncertain.</span></span></p></div><div><h3>Objectives</h3><p>To compare overall mortality risk in patients with moderate-to-severe CKD following TAVI versus SAVR.</p></div><div><h3>Methods</h3><p>Study-level meta-analysis of reconstructed time-to-event data from Kaplan-Meier curves of studies published by August 2022.</p></div><div><h3>Results</h3><p>Nine studies met our inclusion criteria. Patients who underwent TAVI had a higher 5-year mortality compared with patients undergoing SAVR in the overall population (HR 1.56, 95% CI 1.44–1.69, <em>P</em> &lt; 0.001) and in populations with similar risk scores (HR 1.15, 95% CI 1.01–1.31, <em>P</em> = 0.035). The landmark analysis revealed a lower risk of 30-day mortality with TAVI (HR 0.62, 95% CI 0.41–0.94, <em>P</em> = 0.023), followed by similar risk until 7.5 months (HR 1, 95% CI 0.78–1.27, <em>P</em> = 0.978). In contrast, the landmark analysis beyond 7.5 months yielded a reversal of the HR in favor of SAVR (TAVI with HR 1.27, 95% CI 1.08–1.49 <em>P</em> = 0.003).</p></div><div><h3>Conclusions</h3><p>In patients with CKD, TAVI provides an initial survival benefit over SAVR. However, in the long run, a significant survival benefit of SAVR over TAVI was observed. Our findings highlight the need for randomized controlled trials to investigate outcomes in this special population.</p></div>","PeriodicalId":51199,"journal":{"name":"Trends in Cardiovascular Medicine","volume":"34 5","pages":"Pages 317-324"},"PeriodicalIF":7.3,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9577567","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Enhancing cardiovascular risk stratification: Radiomics of coronary plaque and perivascular adipose tissue - Current insights and future perspectives. 加强心血管风险分层：冠状动脉斑块和血管周围脂肪组织的放射组学--当前见解和未来展望。
IF 7.3 2区 医学
Trends in Cardiovascular Medicine Pub Date : 2024-07-01 DOI: 10.1016/j.tcm.2024.06.003
Anna Corti, Francesca Lo Iacono, Francesca Ronchetti, Saima Mushtaq, Gianluca Pontone, Gualtiero I Colombo, Valentina D A Corino
{"title":"Enhancing cardiovascular risk stratification: Radiomics of coronary plaque and perivascular adipose tissue - Current insights and future perspectives.","authors":"Anna Corti, Francesca Lo Iacono, Francesca Ronchetti, Saima Mushtaq, Gianluca Pontone, Gualtiero I Colombo, Valentina D A Corino","doi":"10.1016/j.tcm.2024.06.003","DOIUrl":"10.1016/j.tcm.2024.06.003","url":null,"abstract":"<p><p>Radiomics, the quantitative extraction and mining of features from radiological images, has recently emerged as a promising source of non-invasive image-based cardiovascular biomarkers, potentially revolutionizing diagnostics and risk assessment. This review explores its application within coronary plaques and pericoronary adipose tissue, particularly focusing on plaque characterization and cardiac events prediction. By shedding light on the current state-of-the-art, achievements, and prospective avenues, this review contributes to a deeper understanding of the evolving landscape of radiomics in the context of coronary arteries. Finally, open challenges and existing gaps are emphasized to underscore the need for future efforts aimed at ensuring the robustness and reliability of radiomics studies, facilitating their clinical translation.</p>","PeriodicalId":51199,"journal":{"name":"Trends in Cardiovascular Medicine","volume":" ","pages":""},"PeriodicalIF":7.3,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141499606","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Editorial commentary: The mundane and the profound of QT prolongation in the opioid abuse crisis 社论评论：阿片类药物滥用危机中QT延长的平凡与深刻
IF 7.3 2区 医学
Trends in Cardiovascular Medicine Pub Date : 2024-07-01 DOI: 10.1016/j.tcm.2023.06.001
J. Kevin Donahue
{"title":"Editorial commentary: The mundane and the profound of QT prolongation in the opioid abuse crisis","authors":"J. Kevin Donahue","doi":"10.1016/j.tcm.2023.06.001","DOIUrl":"10.1016/j.tcm.2023.06.001","url":null,"abstract":"","PeriodicalId":51199,"journal":{"name":"Trends in Cardiovascular Medicine","volume":"34 5","pages":"Pages 286-287"},"PeriodicalIF":7.3,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9941334","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Regression and stabilization of atherogenic plaques 致动脉粥样硬化斑块的消退和稳定
IF 7.3 2区 医学
Trends in Cardiovascular Medicine Pub Date : 2024-07-01 DOI: 10.1016/j.tcm.2023.07.002
Jairo Aldana-Bitar , Deepak L. Bhatt , Matthew J. Budoff
{"title":"Regression and stabilization of atherogenic plaques","authors":"Jairo Aldana-Bitar ,&nbsp;Deepak L. Bhatt ,&nbsp;Matthew J. Budoff","doi":"10.1016/j.tcm.2023.07.002","DOIUrl":"10.1016/j.tcm.2023.07.002","url":null,"abstract":"<div><p>Atherosclerotic plaque assessment has become a crucial element in the examination of cardiovascular diseases. Plaque may exhibit progression and could become unstable if not treated, making plaque regression and stabilization among the most important goals of any cardiovascular intervention in cardiovascular medicine. In this review, we explore the current understanding of plaque regression and stabilization, discuss imaging and measurement techniques, and examine the evidence for pharmacological interventions and other interventions aimed at addressing this condition.</p></div>","PeriodicalId":51199,"journal":{"name":"Trends in Cardiovascular Medicine","volume":"34 5","pages":"Pages 340-346"},"PeriodicalIF":7.3,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10301298","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Editorial commentary: Transcatheter aortic valve implantation in bicuspid aortic valve stenosis 编辑评论：双尖瓣主动脉瓣狭窄的经导管主动脉瓣植入术
IF 7.3 2区 医学
Trends in Cardiovascular Medicine Pub Date : 2024-07-01 DOI: 10.1016/j.tcm.2023.05.001
Michel Pompeu Sá , Xander Jacquemyn , Ibrahim Sultan
{"title":"Editorial commentary: Transcatheter aortic valve implantation in bicuspid aortic valve stenosis","authors":"Michel Pompeu Sá ,&nbsp;Xander Jacquemyn ,&nbsp;Ibrahim Sultan","doi":"10.1016/j.tcm.2023.05.001","DOIUrl":"10.1016/j.tcm.2023.05.001","url":null,"abstract":"","PeriodicalId":51199,"journal":{"name":"Trends in Cardiovascular Medicine","volume":"34 5","pages":"Pages 314-316"},"PeriodicalIF":7.3,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9966222","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Editorial commentary: Rhythm control in atrial fibrillation: How the early bird may get the worm 编辑评论：心房颤动的节律控制：早起的鸟儿有虫吃
IF 7.3 2区 医学
Trends in Cardiovascular Medicine Pub Date : 2024-07-01 DOI: 10.1016/j.tcm.2023.04.002
Alexander Turin , Eugene H Chung
{"title":"Editorial commentary: Rhythm control in atrial fibrillation: How the early bird may get the worm","authors":"Alexander Turin ,&nbsp;Eugene H Chung","doi":"10.1016/j.tcm.2023.04.002","DOIUrl":"10.1016/j.tcm.2023.04.002","url":null,"abstract":"","PeriodicalId":51199,"journal":{"name":"Trends in Cardiovascular Medicine","volume":"34 5","pages":"Pages 295-296"},"PeriodicalIF":7.3,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9441536","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Editorial commentary: Understanding the pathology of plaque progression and regression 了解斑块进展和消退的病理学。
IF 7.3 2区 医学
Trends in Cardiovascular Medicine Pub Date : 2024-07-01 DOI: 10.1016/j.tcm.2023.09.004
Arielle Bellissard , Aloke V. Finn , Renu Virmani
{"title":"Editorial commentary: Understanding the pathology of plaque progression and regression","authors":"Arielle Bellissard ,&nbsp;Aloke V. Finn ,&nbsp;Renu Virmani","doi":"10.1016/j.tcm.2023.09.004","DOIUrl":"10.1016/j.tcm.2023.09.004","url":null,"abstract":"","PeriodicalId":51199,"journal":{"name":"Trends in Cardiovascular Medicine","volume":"34 5","pages":"Pages 347-349"},"PeriodicalIF":7.3,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41171830","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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