Trends in Cardiovascular Medicine最新文献_第7页

A call to consider an aortic stenosis screening program 呼吁考虑主动脉瓣狭窄筛查计划

IF 7.3 2区医学

Trends in Cardiovascular Medicine Pub Date : 2024-07-01 DOI: 10.1016/j.tcm.2023.04.003

Ju Young Bae , Arzhang Fallahi , Wayne Miller , Martin B. Leon , Theodore P. Abraham , Sripal Bangalore , David H. Hsi

引用次数: 0

Editorial commentary: Clinical translation of vagus nerve stimulation in cardiovascular diseases: How bright is the light at the end of the tunnel? 编辑评论：迷走神经刺激在心血管疾病中的临床应用：隧道尽头的曙光有多亮？

IF 7.3 2区医学

Trends in Cardiovascular Medicine Pub Date : 2024-07-01 DOI: 10.1016/j.tcm.2023.07.006

Richard L. Verrier

引用次数: 0

Vagus nerve stimulation for cardiovascular diseases: Is there light at the end of the tunnel? 迷走神经刺激治疗心血管疾病：隧道尽头是否有曙光？

IF 7.3 2区医学

Trends in Cardiovascular Medicine Pub Date : 2024-07-01 DOI: 10.1016/j.tcm.2023.07.003

Stefanos Zafeiropoulos , Umair Ahmed , Alexia Bikou , Ibrahim T. Mughrabi , Stavros Stavrakis , Stavros Zanos

引用次数: 0

Opioids-induced inhibition of HERG ion channels and sudden cardiac death, a systematic review of current literature 阿片类药物诱导的 HERG 离子通道抑制与心脏性猝死，当前文献的系统回顾

IF 7.3 2区医学

Trends in Cardiovascular Medicine Pub Date : 2024-07-01 DOI: 10.1016/j.tcm.2023.03.006

Adham El Sherbini , Kiera Liblik , Junsu Lee , Adrian Baranchuk , Shetuan Zhang , Mohammad El-Diasty

{"title":"Opioids-induced inhibition of HERG ion channels and sudden cardiac death, a systematic review of current literature","authors":"Adham El Sherbini , Kiera Liblik , Junsu Lee , Adrian Baranchuk , Shetuan Zhang , Mohammad El-Diasty","doi":"10.1016/j.tcm.2023.03.006","DOIUrl":"10.1016/j.tcm.2023.03.006","url":null,"abstract":"<div><h3>Background</h3><p>It is estimated that over 60 million individuals regularly use opioids globally, with opioid use disorder increasing substantially in the past decade. Several reports have linked sudden cardiac death, QTc prolongation, and other adverse cardiovascular outcomes with opioid use through their inhibitory effect on the human ether-a-go-go-related gene (HERG) ion channel. Therefore, understanding this underlying mechanism may be critical for risk prevention and management in prescribing opioids and treating patients with opioid dependency.</p></div><div><h3>Aim</h3><p>The present systematic review summarizes the current literature on the impact of opioids-induced inhibition of HERG channel function and its relationship with sudden cardiac death, QTc prolongation, and other cardiovascular adverse effects.</p></div><div><h3>Methods</h3><p>A systematic review was conducted of the databases PubMed, EMBASE, Cochrane, and ClinicalTrials.gov of primary studies that reported the effects of opioids on HERG channel function and associated cardiovascular outcomes.</p></div><div><h3>Results</h3><p>The search identified 1,546 studies, of which 12 were finally included for data extraction. Based on the current literature, methadone, oliceridine, l-α-acetylmethadol (LAAM), and fentanyl were found to inhibit the HERG channel function and were associated with QTc prolongation. However, other opioids such as morphine, codeine, tramadol, and buprenorphine were not associated with inhibition of HERG channels or QTc prolongation. Additional cardiac outcomes associated with opioid related HERG channels dysfunction included sudden cardiac death and Torsade de Pointes.</p></div><div><h3>Conclusion</h3><p>Our findings suggest that certain opioid consumption may result in the inhibition of HERG channels, subsequently prolonging the QTc interval and increasing patient susceptibility to sudden cardiac death.</p></div>","PeriodicalId":51199,"journal":{"name":"Trends in Cardiovascular Medicine","volume":"34 5","pages":"Pages 279-285"},"PeriodicalIF":7.3,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9264857","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Benefits of early rhythm control of atrial fibrillation 早期控制心房颤动节律的益处

IF 7.3 2区医学

Trends in Cardiovascular Medicine Pub Date : 2024-07-01 DOI: 10.1016/j.tcm.2023.04.001

L. Eckardt , J. Wolfes , G. Frommeyer

{"title":"Benefits of early rhythm control of atrial fibrillation","authors":"L. Eckardt , J. Wolfes , G. Frommeyer","doi":"10.1016/j.tcm.2023.04.001","DOIUrl":"10.1016/j.tcm.2023.04.001","url":null,"abstract":"<div><p><span><span>In contrast to current guidelines and earlier trials, recent studies demonstrated superiority of rhythm- over rate-control and challenged the strategy of \"rate versus rhythm\" therapy </span>in patients with atrial fibrillation. These newer studies have started to shift the use of rhythm-control therapy from the symptom-driven therapy of current guidelines to a risk-reducing strategy aimed at restoring and maintaining </span>sinus rhythm<span>. This review discusses recent data and presents an overview on the current discourse: The concept of early rhythm control seems attractive. Patients with rhythm control may undergo less atrial remodeling<span><span> compared to those with rate control. In addition, in EAST-AFNET 4 an outcome-reducing effect of rhythm control was achieved by delivering therapy with relatively few complications early after the initial AF diagnosis. Successful rhythm control therapy and most likely reduced AF burden, estimated by the presence of sinus rhythm at 12 months after randomization, explained most of the reduction in cardiovascular outcomes achieved by rhythm control. However, it is too early to call for early rhythm control for all AF patients. Rhythm control may raise concerns regarding the generalizability of trial results in routine practice involving important questions on the definition of \"early\" and \"successful\", and the relevant issue of antiarrhythmic drugs versus </span>catheter ablation. Further information is required to select patients who will benefit from an early ablative or non-ablative rhythm management.</span></span></p></div>","PeriodicalId":51199,"journal":{"name":"Trends in Cardiovascular Medicine","volume":"34 5","pages":"Pages 288-294"},"PeriodicalIF":7.3,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9338007","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

How to build an actionable narrative for cardio-oncology. 如何为心脏肿瘤学编写可操作的叙述。

IF 7.3 2区医学

Trends in Cardiovascular Medicine Pub Date : 2024-06-29 DOI: 10.1016/j.tcm.2024.06.001

Mark T Nolan, Doan T M Ngo, Aaron L Sverdlov

引用次数: 0

Editorial commentary: Infective endocarditis: Harnessing the power of advanced imaging. 编辑评论：感染性心内膜炎：利用先进成像技术的力量。

IF 9.3 2区医学

Trends in Cardiovascular Medicine Pub Date : 2024-06-04 DOI: 10.1016/j.tcm.2024.05.001

Mina Owlia, David H Hsi

引用次数: 0

Electrocardiographic features and rhythm disorders in cardiac amyloidosis 心脏淀粉样变性的心电图特征和心律紊乱。

IF 9.3 2区医学

Trends in Cardiovascular Medicine Pub Date : 2024-05-01 DOI: 10.1016/j.tcm.2023.02.006

Nicolò Martini , Giulio Sinigiani , Laura De Michieli , Roberta Mussinelli , Martina Perazzolo Marra , Sabino Iliceto , Alessandro Zorzi , Stefano Perlini , Domenico Corrado , Alberto Cipriani

{"title":"Electrocardiographic features and rhythm disorders in cardiac amyloidosis","authors":"Nicolò Martini , Giulio Sinigiani , Laura De Michieli , Roberta Mussinelli , Martina Perazzolo Marra , Sabino Iliceto , Alessandro Zorzi , Stefano Perlini , Domenico Corrado , Alberto Cipriani","doi":"10.1016/j.tcm.2023.02.006","DOIUrl":"10.1016/j.tcm.2023.02.006","url":null,"abstract":"<div><p>Cardiac amyloidosis (CA) is an infiltrative cardiomyopathy caused by extracellular deposition of amyloid fibrils, mainly derived from transthyretin, either wild-type or hereditary variants, or immunoglobulin light chains misfolding. It is characterized by an increased left ventricular (LV) mass and diastolic dysfunction, which can lead to heart failure with preserved ejection fraction and/or conduction disturbances. The diagnosis is based on invasive pathology demonstration of amyloid deposits, or non-invasive criteria using advanced cardiovascular imaging techniques. Nevertheless, 12-lead electrocardiogram (ECG) remains of crucial importance in the assessment of patients with CA, since they can manifest peculiar features such as low QRS voltages, in discordance with the LV hypertrophy, but also pseudo-infarction patterns, sinus node dysfunction, atrioventricular blocks, premature supraventricular and ventricular beats, which support the presence of a myocardial disease. Great awareness of these common ECG characteristics of CA is needed to increase diagnostic performance and improve patient's outcome. In the present review, we discuss the current role of the ECG in the diagnosis and management of CA, focusing on the most common ECG abnormalities and rhythm disorders.</p></div>","PeriodicalId":51199,"journal":{"name":"Trends in Cardiovascular Medicine","volume":"34 4","pages":"Pages 257-264"},"PeriodicalIF":9.3,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1050173823000245/pdfft?md5=b000e2010d57610ad96b4740ad34b50c&pid=1-s2.0-S1050173823000245-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9080096","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Conduction system disease in cardiac amyloidosis 心脏淀粉样变性中的传导系统疾病

IF 9.3 2区医学

Trends in Cardiovascular Medicine Pub Date : 2024-05-01 DOI: 10.1016/j.tcm.2023.02.004

Ala’ Assaf, Mario Mekhael, Charbel Noujaim, Nour Chouman, Hadi Younes, Omar Kreidieh, Nassir Marrouche, Eoin Donnellan

引用次数: 0

Editorial commentary: Heart rate and rhythm in cardiac amyloidosis 编辑评论：心脏淀粉样变性的心率和心律

IF 9.3 2区医学

Trends in Cardiovascular Medicine Pub Date : 2024-05-01 DOI: 10.1016/j.tcm.2023.03.004

Brett W. Sperry , Uttsav B. Sandesara , Jessica A Kline

引用次数: 0