Trends in Cardiovascular Medicine最新文献_第5页

Editorial commentary: Navigating the complexities of LVAD emergency management 驾驭 LVAD 紧急情况管理的复杂性。

IF 7.3 2区医学

Trends in Cardiovascular Medicine Pub Date : 2025-04-01 DOI: 10.1016/j.tcm.2024.12.006

Aabha Divya

引用次数: 0

Editorial commentary: Moving the boundaries of the diagnosis of unexplained sudden cardiac arrest and sudden cardiac death in the young 移动年轻人不明原因心脏骤停和心脏性猝死诊断的边界。

IF 7.3 2区医学

Trends in Cardiovascular Medicine Pub Date : 2025-04-01 DOI: 10.1016/j.tcm.2024.12.009

Matteo Vatta

引用次数: 0

Editorial commentary: Applying guidelines directed medical therapy for heart failure: The cardiologist hard job 应用指南指导心力衰竭的药物治疗：心脏病医生的艰巨任务

IF 7.3 2区医学

Trends in Cardiovascular Medicine Pub Date : 2025-04-01 DOI: 10.1016/j.tcm.2024.10.004

Gabriele Fragasso

引用次数: 0

Personalization of primary prevention: Exploring the role of coronary artery calcium and polygenic risk score in cardiovascular diseases 初级预防的个性化：探索冠状动脉钙和多基因风险评分在心血管疾病中的作用。

IF 7.3 2区医学

Trends in Cardiovascular Medicine Pub Date : 2025-04-01 DOI: 10.1016/j.tcm.2024.10.003

Mario Mekhael , Ghassan Bidaoui , Austin Falloon , Amitabh C. Pandey

{"title":"Personalization of primary prevention: Exploring the role of coronary artery calcium and polygenic risk score in cardiovascular diseases","authors":"Mario Mekhael , Ghassan Bidaoui , Austin Falloon , Amitabh C. Pandey","doi":"10.1016/j.tcm.2024.10.003","DOIUrl":"10.1016/j.tcm.2024.10.003","url":null,"abstract":"<div><div>Personalized healthcare is becoming increasingly popular given the vast heterogeneity in disease manifestation between individuals. Many commonly encountered diseases within cardiology are multifactorial in nature and disease progression and response is often variable due to environmental and genetic factors influencing disease states. This makes accurate early identification and primary prevention difficult in certain populations, especially young patients with limited Atherosclerotic Cardiovascular Disease (ASCVD) risk factors. Newer strategies, such as coronary artery calcium (CAC) scans and polygenic risk scores (PRS), are being implemented to aid in the detection of subclinical disease and heritable risk, respectively. Data surrounding CAC scans have shown promising results in their ability to detect subclinical atherosclerosis and predict the risk of future coronary events, especially at the extremes; however, predictive variability exists among different patient populations, limiting the test's specificity. Furthermore, relying only on CAC scores and ASCVD risk scores may fail to identify a large group of patients needing primary prevention who lack subclinical disease and traditional risk factors, but harbor genetic variabilities strongly associated with certain cardiovascular diseases. PRS can overcome these limitations. These scores can be measured in individuals as early as birth to identify genetic variants placing them at elevated risk for developing cardiovascular disease, irrespective of their current cardiovascular health status. By applying PRS alongside CAC scores, previously overlooked patient populations can be identified and begin primary prevention strategies early to achieve optimal outcomes. In this review, we expand on the current knowledge surrounding CAC scores and PRS and highlight the future possibilities of these technologies for preventive cardiology.</div></div>","PeriodicalId":51199,"journal":{"name":"Trends in Cardiovascular Medicine","volume":"35 3","pages":"Pages 154-163"},"PeriodicalIF":7.3,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142512489","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Editorial commentary: Takotsubo syndrome: Be happy, then worry? Takotsubo综合症：先开心后担心？

IF 7.3 2区医学

Trends in Cardiovascular Medicine Pub Date : 2025-04-01 DOI: 10.1016/j.tcm.2024.12.012

J D Horowitz , A M Kucia , T H Nguyen

引用次数: 0

Guidelines for treating heart failure 心力衰竭治疗指南。

IF 7.3 2区医学

Trends in Cardiovascular Medicine Pub Date : 2025-04-01 DOI: 10.1016/j.tcm.2024.10.002

Michelle M. Kittleson

引用次数: 0

Editorial commentary: Polygenic risk and coronary artery calcium score: Joining forces in preventive cardiology 编辑评论：多基因风险与冠状动脉钙化评分：预防性心脏病学中的强强联手。

IF 7.3 2区医学

Trends in Cardiovascular Medicine Pub Date : 2025-04-01 DOI: 10.1016/j.tcm.2024.11.001

Alexandros Kasiakogias, Costas Tsioufis, George Lazaros

引用次数: 0

Unexplained sudden cardiac arrest and sudden cardiac death in the young: What is killing these young people when nothing is found? 年轻人不明原因的心脏骤停和心脏性猝死：在没有任何发现的情况下，是什么夺走了这些年轻人的生命？

IF 7.3 2区医学

Trends in Cardiovascular Medicine Pub Date : 2025-04-01 DOI: 10.1016/j.tcm.2024.11.002

Andrew S. Tseng , Mayank Sardana , John R. Giudicessi , Michael J. Ackerman

{"title":"Unexplained sudden cardiac arrest and sudden cardiac death in the young: What is killing these young people when nothing is found?","authors":"Andrew S. Tseng , Mayank Sardana , John R. Giudicessi , Michael J. Ackerman","doi":"10.1016/j.tcm.2024.11.002","DOIUrl":"10.1016/j.tcm.2024.11.002","url":null,"abstract":"<div><div>Unexplained sudden cardiac arrest (SCA) and sudden cardiac death (SCD) in the young remains a critical issue for clinicians, researchers, patients and their family members. In this review, we explore the current status of SCA and SCD evaluation in the young, including recent monogenic and polygenic disease discoveries, advancements in cardiac imaging and our growing understanding of the role of the Purkinje system in triggering life threatening and even fatal ventricular arrhythmias. Yet, despite these advancements, over a third of SCA and SCD among individuals with seemingly structurally normal hearts remain unexplained. We explore the future role of artificial intelligence, novel biomarkers, multimodality cardiac imaging, genetic discoveries, as well as wearable devices and sensors in closing this current gap. With the overarching framework provided in this review, we envision a future in which collaboration among patients, clinicians, researchers, innovators, and policy makers culminates in our ability to diagnose, predict, and ultimately prevent SCA and SCD in the young.</div></div>","PeriodicalId":51199,"journal":{"name":"Trends in Cardiovascular Medicine","volume":"35 3","pages":"Pages 177-183"},"PeriodicalIF":7.3,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142689532","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Editorial commentary: The birth and growth of Cardio-Obstetrics: Managing cardiovascular risk and disease in pregnancy 心脏产科的出生和成长：管理妊娠期心血管风险和疾病。

IF 7.3 2区医学

Trends in Cardiovascular Medicine Pub Date : 2025-04-01 DOI: 10.1016/j.tcm.2024.11.003

Yuliya Krokhaleva, Marmar Vaseghi

引用次数: 0

Happy heart syndrome – The impact of different triggers on the characteristics of takotsubo syndrome 快乐心综合征：不同触发因素对Takotsubo综合征特征的影响。

IF 7.3 2区医学

Trends in Cardiovascular Medicine Pub Date : 2025-04-01 DOI: 10.1016/j.tcm.2024.12.002

Thomas Stiermaier, Ingo Eitel

引用次数: 0