{"title":"Heart Rate Variability Biofeedback to Manage the Mental Health of Adults With Irritable Bowel Syndrome: A Pilot Study.","authors":"Séphora Minjoz, Rudy Jeanne, Laurent Vercueil, Cécile Sabourdy, Valérie Sinniger, Bruno Bonaz, Pascal Hot, Sonia Pellissier","doi":"10.1002/smi.70015","DOIUrl":"https://doi.org/10.1002/smi.70015","url":null,"abstract":"<p><p>Irritable bowel syndrome [IBS] is classified as a disorder of gut-brain interaction related to stress with no curative option. Heart rate variability biofeedback [HRV-BFB] is a non-drug therapy recently suggested to be relevant in reducing both autonomic nervous system [ANS] dysregulations and psychiatric comorbidities. Nevertheless, empirical evidence is still scarce and only a few studies have tested HRV-BFB in adults with IBS. Our aims were therefore to examine the effectiveness of HRV-BFB training on the psychophysiological states of 29 adults with IBS. The study took place in three sessions, spaced 24 days apart. In all sessions, participants completed self-report questionnaires to assess their psychological state (affectivity, anxiety, depression, perceived stress, coping strategy, life satisfaction, illness cognitions), ANS measurements were then recorded of them at rest, during completion of a mental task (reactivity), and while in recovery following this task. The first 24-day period was a control period without any practice, and the second was an intervention period with HRV-BFB. Participants practiced HRV-BFB daily for 5 min, three times a day, for 24 days. We found that HRV-BFB reduced psychological distress and the feeling of helplessness, and led to a decrease in sympathetic reactivity during the mental task. Our findings support the potential relevance of HRV-BFB to manage mental health in adults with IBS.</p>","PeriodicalId":51175,"journal":{"name":"Stress and Health","volume":"41 1","pages":"e70015"},"PeriodicalIF":3.0,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143411525","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Yun-Han Wang, Myanna Duncan, Katherine S Young, Colette Hirsch
{"title":"Modifiable Psychological Mechanisms of Resilience Among UK Trainee and Newly Qualified Teachers.","authors":"Yun-Han Wang, Myanna Duncan, Katherine S Young, Colette Hirsch","doi":"10.1002/smi.70005","DOIUrl":"10.1002/smi.70005","url":null,"abstract":"<p><p>Teaching is identified as a stressful occupation, with elevated levels of burnout among the profession. Research suggests that resilience may buffer against stress and psychological distress and potentially be a useful resource for this occupational group. This research aimed to identify mechanisms associated with trainee teachers' resilience across time. Using the cognitive model of resilience, we examined interpretation bias and emotion regulation as cognitive mechanisms associated with resilience. The study investigated whether these cognitive processes have an association with trainee teachers' resilience during teacher training and in the first year as teachers in two 1-year longitudinal online studies. Study 1 commenced before COVID-19 pandemic (September 2019), but ended during ongoing pandemic-related restrictions. Study 2 was conducted as a replication study, commenced during COVID-19 (May 2020). Resilience, short-term stress, chronic perceived stress, and cognitive mechanisms (interpretation bias, emotion regulation) were assessed at baseline (during teacher training), with resilience and short-term stress monitored at the 8-month and 13-month follow-ups. Across both studies, cross-sectional and longitudinal relationships were found between perceived stress, cognitive mechanisms, and resilience. Positive interpretation bias predicted trainee teachers' resilience across time, suggesting that it is likely to be a good target for interventions to promote resilience.</p>","PeriodicalId":51175,"journal":{"name":"Stress and Health","volume":"41 1","pages":"e70005"},"PeriodicalIF":3.0,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11750056/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143015792","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Emily Taverna, Katherine M Iverson, Shaina A Kumar, Dawne Vogt, Karen S Mitchell
{"title":"Beyond Physical and Mental Health: The Broader Impacts of Intimate Partner Violence on Psychosocial Well-Being Among Women and Men Veterans.","authors":"Emily Taverna, Katherine M Iverson, Shaina A Kumar, Dawne Vogt, Karen S Mitchell","doi":"10.1002/smi.3526","DOIUrl":"10.1002/smi.3526","url":null,"abstract":"<p><p>Research on the consequences of experiencing intimate partner violence (IPV) has predominantly focused on specific physical and mental health outcomes and have emphasized the impacts for women. Fewer studies have comprehensively documented IPV impacts on other aspects of psychosocial well-being and examined effects for both women and men. A sample of 1133 veterans (52.3% women) completed two web-based surveys approximately one year apart. Women did not differ from men with respect to their odds of experiencing past year overall IPV (OR = 1.06, 95% CI [0.81, 1.38]) but were more likely to experience overall IPV prior to the past year (OR = 1.52, 95% CI [1.19, 1.95]). Gender-stratified multivariate regressions revealed that greater frequency of past year IPV experiences was associated with lower psychosocial well-being with respect to finances (β = -0.22, p < 0.001), health (β = -0.19, p < 0.001), intimate relationships (β = -0.14, p = 0.007), and broader social relationships (β = -0.17, p = 0.018), whereas greater frequency of IPV prior to the past year was associated with lower psychosocial well-being with respect to employment (β = -0.17, p = 0.002), finances (β = -0.14, p = 0.020), and health (β = -0.16, p = 0.012) among women. For men, nonsignificant associations were observed for all associations of IPV with psychosocial well-being outcomes. Results point to the importance of attending to broader aspects of psychosocial well-being that may represent modifiable intervention targets among women who have experienced IPV. Further research is needed to better understand the psychosocial well-being impacts of IPV for men.</p>","PeriodicalId":51175,"journal":{"name":"Stress and Health","volume":"41 1","pages":"e3526"},"PeriodicalIF":3.0,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11898211/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142932974","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jin Hyung Kim, Hakseung Kim, Seho Lee, Sung Ha Kim, Sung Soo Park, Chang Woo Hong, Ki Tae Kwon, Seung Hun Lee, Hyun-Ji Kim, Kyoung Soo Kim, Jung Bin Kim, Hoon Choi, Dong-Joo Kim
{"title":"Enhancing Military Performance and Stress Management Through Mindfulness Training: The Role of Fronto-Limbic Network and Sequential Mediation Analysis.","authors":"Jin Hyung Kim, Hakseung Kim, Seho Lee, Sung Ha Kim, Sung Soo Park, Chang Woo Hong, Ki Tae Kwon, Seung Hun Lee, Hyun-Ji Kim, Kyoung Soo Kim, Jung Bin Kim, Hoon Choi, Dong-Joo Kim","doi":"10.1002/smi.70016","DOIUrl":"https://doi.org/10.1002/smi.70016","url":null,"abstract":"<p><p>Mindfulness training (MT) has been shown to be effective at managing emotions and stress. However, the underlying neural mechanism of MT is yet unclear and attempts to explore the effects of MT on both psychological factors and performance outcomes remain unexplored. Physiological questionnaire, performance measures, and EEG-based Functional connectivity (FC) in the fronto-limbic network were analyzed in both the MT (N = 39) and control (N = 43) groups. Statistical analyses were conducted to evaluate group-wise differences, within-group longitudinal change, and sequential mediation effects. MT group maintained their stress coping capacity and demonstrated improved performance during the military training weeks. There was an increase in FC between the frontal and limbic regions in all frequency bands (i.e., delta, theta, alpha, and beta) in the MT group, yielding a higher FC than the control group in the final week. Furthermore, changes in these FC and changes in stress coping capacities played a sequential mediation role in the association between the MT and changes in military performance. This study demonstrated that MT was effective for military personnel under stressful conditions, in terms of managing stress coping capacity via changes in fronto-limbic FC, and improving task performance.</p>","PeriodicalId":51175,"journal":{"name":"Stress and Health","volume":"41 1","pages":"e70016"},"PeriodicalIF":3.0,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143442753","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Stress and HealthPub Date : 2024-12-01Epub Date: 2024-10-30DOI: 10.1002/smi.3496
Marcin Czub, Marta Kowal, Rosa Esteve Zarazaga, Elena R Serrano-Ibáñez, Gema T Ruíz-Párraga, Carmen Ramírez-Maestre, Alicia E López-Martínez, Charles Paccione, Joanna Piskorz
{"title":"A slow diaphragmatic breathing intervention for anxiety: How do respiration rate and inhalation/exhalation ratio influence self-reported anxiety?","authors":"Marcin Czub, Marta Kowal, Rosa Esteve Zarazaga, Elena R Serrano-Ibáñez, Gema T Ruíz-Párraga, Carmen Ramírez-Maestre, Alicia E López-Martínez, Charles Paccione, Joanna Piskorz","doi":"10.1002/smi.3496","DOIUrl":"10.1002/smi.3496","url":null,"abstract":"<p><p>The primary aim was to investigate how respiration rate and inhalation/exhalation ratio influence self-reported state anxiety during a single slow diaphragmatic breathing exercise session. Eight hundred and twenty-eight participants completed the study at two separate geographical locations (Poland and Spain). Participants performed a 10-min online guided breathing exercise. Respiration rates were sampled from a continuous uniform distribution (ranging from 6 to 12 breaths/min). Similarly, inhalation/exhalation ratios were treated as continuous variables and sampled from a uniform distribution for each participant. An application programed for this experiment displayed visual and auditory cues adjusted for each participant. Before and after the breathing exercise, each participant filled in the Current Anxiety Level Measure questionnaire. Self-trait anxiety was measured with the Clinically Useful Anxiety Outcome Scale. A linear regression model showed that respiration rate, trait anxiety, pre-test anxiety, and nationality (Polish/Spanish) were positively related to post-test anxiety levels. Adding quadratic terms of respiration rate and inhalation/exhalation ratio did not improve model fit. Polish participants exhibited higher post-test anxiety levels compared with the Spanish subsample. Age was negatively associated with post-test anxiety. No significant relationships between inhalation/exhalation ratio and post-test anxiety level were found. Slower respiration rates during a single-session breathing exercise are linearly associated with lower post-test anxiety levels in a large and varied sample. This study is the largest to date and may offer further guidance for predicting expected effect sizes for the relationships between anxiety and respiratory dynamics.</p>","PeriodicalId":51175,"journal":{"name":"Stress and Health","volume":" ","pages":"e3496"},"PeriodicalIF":3.0,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142548834","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Stress and HealthPub Date : 2024-12-01Epub Date: 2024-11-09DOI: 10.1002/smi.3500
Niannian Dong, Ying Zhang, Xiyue Ma, Kui Yin, Yi Liu
{"title":"Carrying Ostracism Overnight: The Cognitive Mechanism Underlying the Effect of Daily Workplace Ostracism on Next-Day Work Engagement.","authors":"Niannian Dong, Ying Zhang, Xiyue Ma, Kui Yin, Yi Liu","doi":"10.1002/smi.3500","DOIUrl":"10.1002/smi.3500","url":null,"abstract":"<p><p>Integrating cognitive appraisal theory of stress and attachment theory, the current study explored the influence of daily workplace ostracism on employee short-term work engagement and examined the mediating role of negative work reflection and the moderating effects of employee attachment styles (i.e., attachment avoidance and attachment anxiety). To test the theoretical model, we employed an experience sampling method to collect daily diary data over 10 consecutive workdays, resulting in a final sample of 834 observations drawn from 133 participants. Results of multilevel path analysis indicated that daily workplace ostracism was negatively related to employee next-day work engagement through negative work reflection at night. In addition, we found that employee attachment avoidance not only moderated the within-person relationship between daily workplace ostracism and negative work reflection at night but also alleviated the indirect effect of daily workplace ostracism on next-day work engagement via negative work reflection at night. Taken together, our study contributed by unfolding the dynamic cognitive appraisal process of workplace ostracism and identifying the significant role of attachment avoidance in shaping employees' cognitive reactions to daily workplace ostracism.</p>","PeriodicalId":51175,"journal":{"name":"Stress and Health","volume":" ","pages":"e3500"},"PeriodicalIF":3.0,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142629841","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Stress and HealthPub Date : 2024-12-01Epub Date: 2024-11-12DOI: 10.1002/smi.3506
Yang Wang, Tingwei Wang, Jiesi Wang, Lingyun Zeng, Guohua Li, Junchang Li, Yongjie Zhou, Yanni Wang
{"title":"The School Bullying Victimization in Adolescents With Non-Suicidal Self-Injury: The Role of Coping Strategies and Emotion Regulation.","authors":"Yang Wang, Tingwei Wang, Jiesi Wang, Lingyun Zeng, Guohua Li, Junchang Li, Yongjie Zhou, Yanni Wang","doi":"10.1002/smi.3506","DOIUrl":"10.1002/smi.3506","url":null,"abstract":"<p><p>The present study aimed to investigate the relationship between school bullying victimization and non-suicidal self-injury (NSSI) frequency, taking into consideration the mediating roles of coping strategies and emotional regulation. Participants were 12-18-year-old outpatients and inpatients who met the NSSI and depressive disorder criteria according to the DSM-5. Assessments included the Multidimensional Peer-Victimization Scale, Coping Style Scale for Middle School Students, Emotion Regulation Questionnaire for Children and Adolescents, and the Functional Assessment of Self-Mutilation to examine the bullying victimization, coping strategies, emotion regulation, and NSSI behaviour. Serial multiple mediation effects of coping strategies and emotion regulation between bullying victimization and NSSI frequency were analysed using the SPSS macro PROCESS programme. A total of 2335 participants were included in this study. Bullying victimization significantly predicted NSSI frequency (B = 0.191, p < 0.001). Both coping strategies and emotion regulation were important mediators in the relationship between bullying victimization and NSSI frequency. Bullying victimization indirectly affected NSSI through two serial mediation pathways: (1) bullying victimization → problem-focused coping → cognitive reappraisal → NSSI frequency, and (2) bullying victimization → emotion-focused coping→ expressive suppression → NSSI frequency. The study revealed a positive association between bullying victimization and the frequency of NSSI among adolescents with depressive disorder. Strategies of coping and emotional regulation significantly mediated the link between bullying victimization and the frequency of NSSI. The findings suggested that supporting adolescents in adopting effective coping and emotional regulation strategies could be a crucial approach to mitigate the impact of bullying victimization on the frequency of NSSI.</p>","PeriodicalId":51175,"journal":{"name":"Stress and Health","volume":" ","pages":"e3506"},"PeriodicalIF":3.0,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142631045","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Stress and HealthPub Date : 2024-12-01Epub Date: 2024-09-27DOI: 10.1002/smi.3481
Néstor Montoro-Pérez, Raúl Alós-Maldonado, Raimunda Montejano-Lozoya, Miguel Richart-Martínez, Nieves Martínez-Alzamora
{"title":"A systematic review and meta-analysis of the parental stress scale's psychometric properties.","authors":"Néstor Montoro-Pérez, Raúl Alós-Maldonado, Raimunda Montejano-Lozoya, Miguel Richart-Martínez, Nieves Martínez-Alzamora","doi":"10.1002/smi.3481","DOIUrl":"10.1002/smi.3481","url":null,"abstract":"<p><p>Parental stress can affect the ability of parents to cope with the challenges of raising children. The result can be a negative cycle within the family dynamic, which in turn can interfere with children's development and emotional regulation. Among the many instruments available to assess parental stress, the Parental Stress Scale (PSS) deserves particular mention. To our knowledge, there are currently no systematic reviews evaluating the psychometric properties of the PSS. The aim of this systematic review was to assess the psychometric properties of the PSS using the COSMIN (COnsensus-based Standards for the selection of health Measurement INstruments) methodology and to conduct a meta-analysis. A thorough literature search was conducted from different databases. A meta-analysis to test the generalisability of PSS internal consistency across its component factors was performed. A total of 20 validation studies of the PSS were identified. Based on the COSMIN methodology, this instrument receives an 'A' rating, meaning that it is considered to be a cross-sectional instrument with the necessary scientific evidence for the assessment of the construct of parental stress. The meta-analysis testing the generalisability of its internal consistency yielded satisfactory results across the different factors. Future research should focus on those psychometric properties of the PSS that have not been studied as extensively, such as reproducibility, responsiveness, measurement error, and measurement invariance.</p>","PeriodicalId":51175,"journal":{"name":"Stress and Health","volume":" ","pages":"e3481"},"PeriodicalIF":3.0,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142331935","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Understanding Resilience in Parents: Longitudinal Examination of Trait Resilience, Stressful Life Events, and Psychological Distress Symptoms-Insights From the FinnBrain Study.","authors":"Viivi Mondolin, Hasse Karlsson, Laura Perasto, Jetro J Tuulari, Linnea Karlsson, Eeva-Leena Kataja","doi":"10.1002/smi.3516","DOIUrl":"10.1002/smi.3516","url":null,"abstract":"<p><p>The study aimed to investigate the persistence or changes in trait resilience of parents over a 6-year period and its association with stressful life events (SLEs). Furthermore, we explored the potential protective effect of trait resilience against exposure to stressful life events and their negative mental health consequences. The study population was drawn from the ongoing FinnBrain Birth Cohort Study and included 1388 mothers and 657 fathers who completed the CD-RISC-10 questionnaire during pregnancy and again 6 years later. Data collection involved self-report questionnaires, including CD-RISC-10, EPDS, SCL-90, and a questionnaire on SLEs. Data analysis utilised linear regression and statistical assessments. Parents in the highest or lowest quartile of resilience showed greater stability in resilience scores over time compared to those in the middle quartiles. Trait resilience during pregnancy was significantly associated with resilience 6 years later. SLEs did not moderate this association. Additionally, higher trait resilience consistently associated with lower levels of distress symptoms. The investigation of SLEs may require more nuance due to their event-specific variability of impact. Furthermore, the study's sample size of individuals who experienced a high frequency of stressful life events was limited. Trait resilience appears to be rather stable, but also susceptible to some change. Because of its persistency and the positive impact on mental health it is worthwhile to be assessed as a part of comprehensive evaluation of parents' mental health.</p>","PeriodicalId":51175,"journal":{"name":"Stress and Health","volume":" ","pages":"e3516"},"PeriodicalIF":3.0,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11636431/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142774639","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Stress and HealthPub Date : 2024-12-01Epub Date: 2024-11-14DOI: 10.1002/smi.3499
N Barrantes-Vidal, A Gizdic, P Torrecilla, P Mas-Bermejo, T Sheinbaum, S Papiol, G Lafit, I Myin-Germeys, A Rosa, T R Kwapil
{"title":"The Interaction of Polygenic Susceptibility to Stress and Childhood Adversity Dimensions Predicts Longitudinal Trajectories of Stress-Sensitivity.","authors":"N Barrantes-Vidal, A Gizdic, P Torrecilla, P Mas-Bermejo, T Sheinbaum, S Papiol, G Lafit, I Myin-Germeys, A Rosa, T R Kwapil","doi":"10.1002/smi.3499","DOIUrl":"10.1002/smi.3499","url":null,"abstract":"<p><p>Stress-sensitivity (SS) is considered a psychobiological trait possibly resulting from the interaction of genetic and environmental factors (GxE). This study examined whether the interaction of SS-related genetic markers with interview-based dimensions of childhood adversity predicted longitudinal trajectories of low versus high SS. Participants were nonclinically-ascertained young adults comprising normative and elevated scores on schizotypy. SS trajectories were defined in a previous report based on three prospective assessments (23.5, 25, 28 years-old) of both retrospective (Perceived Stress Scale; PSS) and momentary (Experience Sampling Methodology; ESM) stress ratings. A total of n = 177 and n = 165 participants with PSS and ESM stress-sensitivity trajectories, respectively, as well as genetic data, were included in the study. GxE effects between a SS Polygenic Risk Score (PRS-SS) and a Genetic Risk Score of the Hypothalamic Pituitary Adrenal axis (GRS-HPA) with childhood adversity dimensions (Intrafamilial Adversity, Threat and Deprivation) on SS trajectories were examined. Threat was the most consistent predictor of persistently high SS. PRS-SS moderated the association of Threat with high-PSS. GRS-HPA moderated the effects of all adversity dimensions on high-PSS. The interaction of PRS-SS with Deprivation and GRS-HPA with Intrafamilial Adversity predicted trajectories of momentary social stress, but the effects were driven by those with lower genetic susceptibility. Genetic-HPA-axis moderates the effects of all adversity dimensions on persistent SS trajectories, as well as PRS-SS and Threat, particularly for retrospective stress measure. The findings highlight the complex interplay between GxE factors and suggest that PSS may better capture SS trait. Including biologically-meaningful GRS indexing SS and adversity dimensions in future studies using comprehensive stress measures would enhance our knowledge on high SS susceptibility and its relationship with diverse psychopathological outcomes.</p>","PeriodicalId":51175,"journal":{"name":"Stress and Health","volume":" ","pages":"e3499"},"PeriodicalIF":3.0,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11636442/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142631008","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}