Nanoscale Research Letters最新文献

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Controlled growth of citrate-stabilized gold nanoparticles using a semi-continuous seed-mediated route 利用半连续种子介导途径控制柠檬酸稳定金纳米颗粒的生长
IF 5.5 3区 材料科学
Nanoscale Research Letters Pub Date : 2025-02-17 DOI: 10.1186/s11671-025-04189-8
Muhammad Bilal, Sulalit Bandyopadhyay
{"title":"Controlled growth of citrate-stabilized gold nanoparticles using a semi-continuous seed-mediated route","authors":"Muhammad Bilal,&nbsp;Sulalit Bandyopadhyay","doi":"10.1186/s11671-025-04189-8","DOIUrl":"10.1186/s11671-025-04189-8","url":null,"abstract":"<div><p>Gold nanoparticles (Au NPs) hold unique optical and electronic properties due to their surface plasmon resonance. The size, shape, and surface chemistry of Au NPs are key parameters for altering their optical properties to fine-tune Au NPs for specific applications. We report a size-controlled synthesis of citrate-stabilized Au NPs via the Turkevich method, followed by their growth through a semi-continuous seed-mediated approach. Au NPs of up to 53 nm were synthesized by controlled addition of chloroauric acid (HAuCl₄) to pre-prepared citrate stabilized Au NP seeds. Our approach leverages the residual sodium citrate from the Turkevich reaction to reduce HAuCl₄ during seed-mediated growth of Au NPs. Notably, we observed that a boiling temperature, as opposed to 70 °C, provided better control over nanoparticle size and morphology. Our method addresses several challenges associated with seed-mediated growth by yielding relatively spherical, monodisperse, citrate-stabilized, water-dispersible Au NPs in a single growth step, without sacrificing yield. Furthermore, a kinetics study revealed a continuous increase in particle diameter over the reaction period, hinting at the continuous and uniform growth of Au NPs.</p></div>","PeriodicalId":51136,"journal":{"name":"Nanoscale Research Letters","volume":"20 1","pages":""},"PeriodicalIF":5.5,"publicationDate":"2025-02-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://link.springer.com/content/pdf/10.1186/s11671-025-04189-8.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143430957","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Influence of fiber dimensions on the mechanical properties of silica glass nanofibers 纤维尺寸对二氧化硅玻璃纳米纤维力学性能的影响
IF 5.5 3区 材料科学
Nanoscale Research Letters Pub Date : 2025-02-14 DOI: 10.1186/s11671-025-04210-0
Raúl Barciela, Félix Quintero, Thiruvilla S. Mahadevan, Antonio Riveiro, Juan Pou, Jincheng Du
{"title":"Influence of fiber dimensions on the mechanical properties of silica glass nanofibers","authors":"Raúl Barciela,&nbsp;Félix Quintero,&nbsp;Thiruvilla S. Mahadevan,&nbsp;Antonio Riveiro,&nbsp;Juan Pou,&nbsp;Jincheng Du","doi":"10.1186/s11671-025-04210-0","DOIUrl":"10.1186/s11671-025-04210-0","url":null,"abstract":"<div><p>The understanding of the mechanical properties in glass nanofibers remains a challenge. As the fiber diameter decreases, surface-to-volume atom fraction increases, making the impact of surface defects more significant. To elucidate these effects, we employed classical molecular dynamics (MD) simulations to investigate how fiber dimensions and the surface layer influence the mechanical properties of silica glass nanofibers. Our simulation methodology included fibers of varying diameters, generated using two different production methods (i.e. “cutting” and “casting” methods) that produce different degrees of surface atomic defects, and compared with bulk samples without surface atoms. The defect-rich surface layer of these fibers was carefully analyzed. Then, MD tensile simulations were performed to analyze the effect of the fiber surface on the mechanical properties and to explain the onset of the brittle-to-ductile transition experimentally observed at a few tens of nanometers. The results revealed that the surface layer maintains a fixed thickness independent of the fiber diameter, resulting in a pronounced increase of the fiber defects in thin fibers. Also, the tensile test simulations show that surface defects significantly reduce tensile strength, without appreciably increasing ductility compared to bulk samples. In turn, we show that the brittle-to-ductile transition is not caused by the surface defects, but related to a balance between fracture energy and elastic energy, which varies with fiber length. Using experimental values of different glass properties, our theory predicted a threshold length of around 200 nm, below which ductile fracture dominates, in reasonable agreement with experimental results.</p><h3>Graphic abstract</h3><div><figure><div><div><picture><source><img></source></picture></div></div></figure></div></div>","PeriodicalId":51136,"journal":{"name":"Nanoscale Research Letters","volume":"20 1","pages":""},"PeriodicalIF":5.5,"publicationDate":"2025-02-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://link.springer.com/content/pdf/10.1186/s11671-025-04210-0.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143423151","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Nanotechnology in the manufacturing of sustainable food packaging: a review 纳米技术在可持续食品包装制造中的应用综述。
IF 5.5 3区 材料科学
Nanoscale Research Letters Pub Date : 2025-02-14 DOI: 10.1186/s11671-025-04213-x
Sabyasachi Ghosh, Rakesh Kumar Mandal, Ayan Mukherjee, Swarup Roy
{"title":"Nanotechnology in the manufacturing of sustainable food packaging: a review","authors":"Sabyasachi Ghosh,&nbsp;Rakesh Kumar Mandal,&nbsp;Ayan Mukherjee,&nbsp;Swarup Roy","doi":"10.1186/s11671-025-04213-x","DOIUrl":"10.1186/s11671-025-04213-x","url":null,"abstract":"<div><p>At present, there is an escalating concern among consumers regarding the spoilage and safety of food items. Furthermore, the packaging materials used within the packaging industry are typically unsustainable food packaging. To confront this significant challenge, nanotechnology may offer a feasible alternative to standard packaging practices. Several naturally derived polymers are capable of substituting petrochemical-based polymers. The application of biopolymers has demonstrated an ability to prolong the shelf life of food items. However, these materials frequently exhibit limited functionality. The incorporation of nanomaterials can significantly enhance the capabilities of these films. Furthermore, the fields of nanotechnology and food packaging are trending areas of research that hold promise for addressing various challenges within the packaging sector. Integrating nanomaterials into food packaging materials yields significant advantages relative to traditional packaging approaches. It contributes to enhanced food quality and safety, provides consumers with insights into their dietary practices, enables the repair of packaging tears, and increases the longevity of food storage. Incorporating various nanomaterials into biobased films has gained prominence in sustainable food packaging. This review explores the general overview of the historical perspective of nanotechnology. In addition, we addressed the various kinds of nanomaterials involved in food packaging. The functions of nanomaterials in food packaging applications are briefly reviewed. The compilation and discussion highlight the nanotechnology for safe, sustainable, and satisfiable food packaging. Finally, the toxicity, safety, and future trends of the nanomaterials in sustainable food packaging were briefly summarized. This review underscores the necessity of nanotechnology in sustainable food packaging.</p></div>","PeriodicalId":51136,"journal":{"name":"Nanoscale Research Letters","volume":"20 1","pages":""},"PeriodicalIF":5.5,"publicationDate":"2025-02-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://link.springer.com/content/pdf/10.1186/s11671-025-04213-x.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143416330","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Superresolution based on coherent thermal radiation with selective information 基于选择性相干热辐射的超分辨率
IF 5.5 3区 材料科学
Nanoscale Research Letters Pub Date : 2025-02-13 DOI: 10.1186/s11671-025-04209-7
Duan-Hsin Huang, Chih-Wei Chang
{"title":"Superresolution based on coherent thermal radiation with selective information","authors":"Duan-Hsin Huang,&nbsp;Chih-Wei Chang","doi":"10.1186/s11671-025-04209-7","DOIUrl":"10.1186/s11671-025-04209-7","url":null,"abstract":"<div><p>We reexamine superresolution methods that may have been overlooked by previous optical microscopy techniques. For a one-dimensional (1D) system, we show that maximizing the information capacity of an imaging system is not a necessary condition for surpassing the Abbe diffraction limit. Specifically, the spatial resolution of two coherent emitters can go beyond the Abbe diffraction limit if an appropriate information zone, but not the full information zone, is selected for far-field imaging. Based on this principle, we show that <i>λ</i>/2.6 superresolution can be easily achieved for two coherent thermal radiative sources with a sufficiently large phase difference. Similar effects can be found for a 1D array of thermal radiative sources coupled by surface phonon polaritons. Introducing a dielectric microsphere into the system can further enhance the phase difference among the radiative sources, achieving superresolution better than <i>λ</i>/4. The concept and method presented here can be implemented to enhance the spatial resolution of thermal imaging.</p></div>","PeriodicalId":51136,"journal":{"name":"Nanoscale Research Letters","volume":"20 1","pages":""},"PeriodicalIF":5.5,"publicationDate":"2025-02-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://link.springer.com/content/pdf/10.1186/s11671-025-04209-7.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143404232","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Eco-friendly synthesis of ZnO, CuO, and ZnO/CuO nanoparticles using extract of spent Pleurotus ostreatus substrate, and their antioxidant and anticancer activities 利用废平菇底物提取物环保合成ZnO、CuO和ZnO/CuO纳米颗粒及其抗氧化和抗癌活性研究
IF 5.5 3区 材料科学
Nanoscale Research Letters Pub Date : 2025-02-13 DOI: 10.1186/s11671-025-04199-6
Simangele Ngwenya, Nkanyiso J. Sithole, Khosi Ramachela, Doctor M. N. Mthiyane, Mulunda Mwanza, Moganavelli Singh, Damian C. Onwudiwe
{"title":"Eco-friendly synthesis of ZnO, CuO, and ZnO/CuO nanoparticles using extract of spent Pleurotus ostreatus substrate, and their antioxidant and anticancer activities","authors":"Simangele Ngwenya,&nbsp;Nkanyiso J. Sithole,&nbsp;Khosi Ramachela,&nbsp;Doctor M. N. Mthiyane,&nbsp;Mulunda Mwanza,&nbsp;Moganavelli Singh,&nbsp;Damian C. Onwudiwe","doi":"10.1186/s11671-025-04199-6","DOIUrl":"10.1186/s11671-025-04199-6","url":null,"abstract":"<div><p>Biosynthesis techniques for nanomaterials have advanced significantly, promoting eco-friendly synthesis chemistry as a sustainable alternative to conventional methods. This study presents a novel and environmentally friendly approach for synthesizing nanoparticulate ZnO, CuO, and ZnO/CuO nanocomposites using aqueous extracts of <i>Pleurotus ostreatus</i> spent substrate, is reported. The structural, optical, and morphological properties of the synthesized NPs were analysed. A hexagonal phase of ZnO NPs and a monoclinic phase of CuO NPs were obtained according to the X-ray diffraction analysis. A reduction in the peak intensity of these metal oxides was observed in the ZnO/CuO NPs due to reduced crystallinity. The absorption spectra, obtained from the UV–vis analysis, showed peaks at 354, 365, and 525 nm for the ZnO, CuO, and ZnO/CuO NPs, respectively. An anticancer assay of the NPs was conducted using human embryonic kidney (HEK 293) and cervical carcinoma (HeLa) cell lines, while a 1,1-diphenyl-2-picrylhydrazyl (DPPH) assay was used for the antioxidant evaluation. The ZnO, CuO, and ZnO/CuO NPs showed higher antioxidant potency with IC<sub>50</sub> of 2.15, 2.16, and 3.18 µg/mL, respectively, than the ascorbic acid (4.25 µg/mL). This indicates that the nanoparticles were more effective in capturing DPPH free radicals. Anticancer assays showed strong cytotoxic effects for all nanoparticles, with ZnO NPs exhibiting the highest activity (IC<sub>50</sub>: 1.94 μM for HEK 293 cells, 3.23 μM for HeLa cells), surpassing CuO and ZnO/CuO NPs. Cell viability for both HEK 293 and HeLa cells decreased as nanoparticle concentration increased, confirming dose-dependent cytotoxicity. The green synthesized metal oxides and their composite have the potential for biomedical applications.</p></div>","PeriodicalId":51136,"journal":{"name":"Nanoscale Research Letters","volume":"20 1","pages":""},"PeriodicalIF":5.5,"publicationDate":"2025-02-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://link.springer.com/content/pdf/10.1186/s11671-025-04199-6.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143404231","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Nanodelivery of nucleic acids for plant genetic engineering 植物基因工程中核酸的纳米递送
IF 5.5 3区 材料科学
Nanoscale Research Letters Pub Date : 2025-02-12 DOI: 10.1186/s11671-025-04207-9
Shufeng Liu, Yixian Zheng, Linsi Pan, Wencai Wang, Yongquan Li, Zhaojun Liu, Xianzhi Zhang
{"title":"Nanodelivery of nucleic acids for plant genetic engineering","authors":"Shufeng Liu,&nbsp;Yixian Zheng,&nbsp;Linsi Pan,&nbsp;Wencai Wang,&nbsp;Yongquan Li,&nbsp;Zhaojun Liu,&nbsp;Xianzhi Zhang","doi":"10.1186/s11671-025-04207-9","DOIUrl":"10.1186/s11671-025-04207-9","url":null,"abstract":"<div><p>Genetic engineering in plants serves as a crucial method for enhancing crop quality, yield, and climate resilience through the manipulation of genetic circuits. A novel genetic transformation approach utilizing nanocarriers as a sound plant genetic engineering technique enables the delivery of DNAs or RNAs into the plant cells. Significant advances have recently been made on the nanotechnology-based delivery of nucleic acids in plants. In this review, several nanoparticle-mediated DNA and RNA delivery systems are discussed respectively, involving latest progresses and drawbacks of these approaches used in plant genetic engineering. We also underscores the current challenges that must be addressed in the implementation of nanoparticles-based strategies for plant gene delivery. Furthermore and more importantly, plant-derived exosome-like nanoparticles that facilitate nucleic acids transfer between organisms was initially proposed as a novel and promising nanodelivery platform for the CRISPR/Cas9 genome editing toolkit in plants. We believe that this review will be beneficial for an effective exploration of nucleic acid nanodelivery to aid the plant genetic engineering in modern agriculture.</p></div>","PeriodicalId":51136,"journal":{"name":"Nanoscale Research Letters","volume":"20 1","pages":""},"PeriodicalIF":5.5,"publicationDate":"2025-02-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://link.springer.com/content/pdf/10.1186/s11671-025-04207-9.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143396522","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Paraffin-based composites containing high density particles: lead and bismuth and its’ oxides as γ-ray shielding materials: an experimental study 含高密度颗粒的石蜡基复合材料:铅、铋及其氧化物作为γ射线屏蔽材料的实验研究
IF 5.5 3区 材料科学
Nanoscale Research Letters Pub Date : 2025-02-12 DOI: 10.1186/s11671-025-04203-z
Jolanta Sobczak, Krzysztof Cioch, Gaweł Żyła
{"title":"Paraffin-based composites containing high density particles: lead and bismuth and its’ oxides as γ-ray shielding materials: an experimental study","authors":"Jolanta Sobczak,&nbsp;Krzysztof Cioch,&nbsp;Gaweł Żyła","doi":"10.1186/s11671-025-04203-z","DOIUrl":"10.1186/s11671-025-04203-z","url":null,"abstract":"<div><p>Shielding nano- and microcomposites have emerged as a promising solution in the constantly growing requirements and expectations in the field of radiological protection. The majority of gamma and X-ray shielding nanocomposites are based on polymers due to lightweight, low cost and flexibility as the inviting features in comparison to traditional lead shields. Taking this into consideration, the following study proposes gamma-ray shielding composites characterized by their susceptibility to shape change using the heat and manual pressure. The paraffin-based composites were filled with pure lead and bismuth particles (Bi and Pb, in one mass fraction: 10 wt%) as well as it’s oxides: bismuth (III) oxide (Bi<sub>2</sub>O<sub>3</sub>) particles and lead (II,IV) oxide particles (Pb<sub>3</sub>O<sub>4</sub>) (manufactured in two concentrations: 10 and 50 wt%). Based on experimental studies utilizing <sup>60</sup>Co the half-value layers were calculated approximately 13–14 cm and ca. 9 cm for 10 wt% and 50 wt% filler concentration, respectively. The relatively quick and straightforward manufacturing process, utilizing two commercially available components, allows for the production of a gamma-ray shielding composite featuring a variety of shape choices, facilitating its use in areas where acquiring complex shields remains problematic, or the desired shape development requires repetition of the production process, changes in some of its stages and modification of the composition.</p></div>","PeriodicalId":51136,"journal":{"name":"Nanoscale Research Letters","volume":"20 1","pages":""},"PeriodicalIF":5.5,"publicationDate":"2025-02-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://link.springer.com/content/pdf/10.1186/s11671-025-04203-z.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143396520","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Design and simulation of a highly efficient eco-friendly, non-toxic perovskite solar cell 一种高效、环保、无毒的钙钛矿太阳能电池的设计与模拟
IF 5.5 3区 材料科学
Nanoscale Research Letters Pub Date : 2025-02-12 DOI: 10.1186/s11671-025-04190-1
G. S. Ahathiyan, H. Victor Du John, D. Jackuline Moni, K. Martin Sagayam, Binay Kumar Pandey, Digvijay Pandey, Mesfin Esayas Lelisho
{"title":"Design and simulation of a highly efficient eco-friendly, non-toxic perovskite solar cell","authors":"G. S. Ahathiyan,&nbsp;H. Victor Du John,&nbsp;D. Jackuline Moni,&nbsp;K. Martin Sagayam,&nbsp;Binay Kumar Pandey,&nbsp;Digvijay Pandey,&nbsp;Mesfin Esayas Lelisho","doi":"10.1186/s11671-025-04190-1","DOIUrl":"10.1186/s11671-025-04190-1","url":null,"abstract":"<div><p>A highly efficient and nontoxic material methylammoniumtin(II) iodideperovskite solar cell is proposed. This proposed solar cell uses CH<sub>3</sub>NH<sub>3</sub>SnI<sub>3</sub> as the absorber layer, TiO<sub>2</sub> as an Electron transport layer (ETL), Indium tin oxide as a buffer layer, and Copper(I) oxide as the hole transport layer (HTL). The device is simulated using the SCAPS-1D simulation tool. This study details the optimization of a set of parameters, including the defect densities and the thickness of the absorber layer. The proposed structure is highly optimized result of 31.73% of enhanced power conversion efficiency (PCE), a J<sub>SC</sub> of 24.526 mA/cm<sup>2</sup> (short-circuit current), FF of 81.40% (fill factor), and a V<sub>OC</sub> of 1.56 V (open-circuit voltage) is obtained through simulation process. Compared to previously reported works, the performance of the device has improved significantly due to better optimization. Along with this electrical characteristic temperature analyses, conductance voltage, capacitance–voltage, and bandgap analyses have also been carried out to examine the device’s efficiency and performance.</p></div>","PeriodicalId":51136,"journal":{"name":"Nanoscale Research Letters","volume":"20 1","pages":""},"PeriodicalIF":5.5,"publicationDate":"2025-02-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://link.springer.com/content/pdf/10.1186/s11671-025-04190-1.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143396519","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Fabrication of lipid-modified drug nanocrystals loaded injectable hydrogel for breast cancer therapy 载可注射水凝胶的脂质修饰药物纳米晶体制备用于乳腺癌治疗
IF 5.5 3区 材料科学
Nanoscale Research Letters Pub Date : 2025-02-12 DOI: 10.1186/s11671-025-04195-w
Manish Kumar, Abhishek Jha, Pooja Goswami, Ritika Srivastava, Manjit Manjit, Kanchan Bharti, Biplob Koch, Brahmeshwar Mishra
{"title":"Fabrication of lipid-modified drug nanocrystals loaded injectable hydrogel for breast cancer therapy","authors":"Manish Kumar,&nbsp;Abhishek Jha,&nbsp;Pooja Goswami,&nbsp;Ritika Srivastava,&nbsp;Manjit Manjit,&nbsp;Kanchan Bharti,&nbsp;Biplob Koch,&nbsp;Brahmeshwar Mishra","doi":"10.1186/s11671-025-04195-w","DOIUrl":"10.1186/s11671-025-04195-w","url":null,"abstract":"<div><p>The current study includes the design of soluplus stabilized, lipid-coated, and fucoidan-oleylamine conjugate modified paclitaxel nanocrystals. The nanocrystals (Lipid-NCs) were about 100 nm, homogeneous, stable and showed improved drug release compared to pure PTX. The nanocrystals were subsequently loaded in an in situ gel-forming hydrogel for the intratumoral injection. The resulting hydrogel exhibited a sol-form at the lower temperature of 2–8 °C while converted to a gel-form at the body temperature. The injectable hydrogel had a reasonable viscosity, an acceptable pH, good syringeability, and a quick sol–gel transition. The hydrogel demonstrated high payload potential, homogeneous distribution, and controlled long-term drug release. In vivo studies revealed the higher efficacy of Lipid-NCs hydrogel in tumor inhibition while avoiding systemic toxicity, compared to pure PTX-loaded hydrogel and intravenously administered PTX. In conclusion, nanocrystal-loaded hydrogel is a promising localized drug delivery system for breast cancer therapy.</p><h3>Graphical abstract</h3>\u0000<div><figure><div><div><picture><source><img></source></picture></div></div></figure></div></div>","PeriodicalId":51136,"journal":{"name":"Nanoscale Research Letters","volume":"20 1","pages":""},"PeriodicalIF":5.5,"publicationDate":"2025-02-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://link.springer.com/content/pdf/10.1186/s11671-025-04195-w.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143396521","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Synthesis of SrAl2O4 and MgCoO2 bimetallic inorganic nanomaterials for thermal and electrochemical applications 热和电化学双金属无机纳米材料SrAl2O4和MgCoO2的合成
IF 5.5 3区 材料科学
Nanoscale Research Letters Pub Date : 2025-02-11 DOI: 10.1186/s11671-025-04198-7
Arunkumar Lagashetty, B. J. Girija, H. Mohana, B. Jyothibai, Roja Kasal, B. M. Roja, J. Thipperudrappa
{"title":"Synthesis of SrAl2O4 and MgCoO2 bimetallic inorganic nanomaterials for thermal and electrochemical applications","authors":"Arunkumar Lagashetty,&nbsp;B. J. Girija,&nbsp;H. Mohana,&nbsp;B. Jyothibai,&nbsp;Roja Kasal,&nbsp;B. M. Roja,&nbsp;J. Thipperudrappa","doi":"10.1186/s11671-025-04198-7","DOIUrl":"10.1186/s11671-025-04198-7","url":null,"abstract":"<div><p>Bimetallic inorganic nanoparticles are vital due to their high biocompatibility, stability and comparatively less toxicity. Nanosized bimetallic oxide materials have been extensively studied worldwide due to their unique properties such as electrical, magnetic and mechanical properties. Present work is reporting the size-controlled synthesis of strontium aluminate and magnesium cobaltate nanoparticles (SrAl<sub>2</sub>O<sub>4</sub> and MgCoO<sub>2</sub>) by self-propagating combustion reaction using polymer fuel. Size of the prepared SrAl<sub>2</sub>O<sub>4</sub> and MgCoO<sub>2</sub> samples distributed on the DLS spectrum was 76 nm and 100 nm respectively. The structural and morphological characterization of the prepared nano oxide samples were carried out by X-ray diffraction (XRD) and scanning electron microscope (SEM) analysis respectively. It shows high crystalline and compact nature of the samples. FT-IR instrumentation was used to study the bonding nature of both the oxide nano samples. Formation of metal oxide and metal–metal bonding can supports the sample formation. EDX analysis carried out to further confirm the presence of Sr, Al, Mg and Co metals and also characteristics absorption peaks of signals demonstrate the final phases of the samples. UV–vis spectroscopic analysis and fluorescence study of the samples was undertaken to know the absorption and emission behaviour respectively. In continuation, the thermal and electrochemical studies of prepared samples were analyzed. Thermal investigation assesses the thermal behaviour of the samples, which shows high thermal stability. The preliminary results of CV study concluding that, the samples are electro active nature and also show possible electrochemical applications. The insights gained from this work contribute to the growing body of knowledge in metal oxide nanomaterials and pave the way for innovations in electrical and thermal-related technologies.</p></div>","PeriodicalId":51136,"journal":{"name":"Nanoscale Research Letters","volume":"20 1","pages":""},"PeriodicalIF":5.5,"publicationDate":"2025-02-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://link.springer.com/content/pdf/10.1186/s11671-025-04198-7.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143388717","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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