European Journal of Oncology Nursing最新文献

{"title":"Symptom experience and self-management strategies of adults undergoing hematopoietic stem cell transplantation after hospital discharge: A longitudinal qualitative study","authors":"","doi":"10.1016/j.ejon.2024.102666","DOIUrl":"10.1016/j.ejon.2024.102666","url":null,"abstract":"<div><h3>Purpose</h3><p>To explore the symptom experience and self-management strategies of adults undergoing hematopoietic stem cell transplantation after hospital discharge.</p></div><div><h3>Methods</h3><p>A longitudinal qualitative study was employed. A heterogeneous sample of 22 patients who underwent hematopoietic stem cell transplantation from August 2022 to April 2023 were included. Semi-structured interviews were conducted at three time points post-discharge and provided a dataset of 56 interviews. The content analysis method was used for manual analysis. This study followed the COREQ checklist.</p></div><div><h3>Results</h3><p>The data from this study were categorized into four themes and 14 subthemes: (1) complexity and multidimensionality of symptom experience: diversity, dynamism, continuity, relatedness, and functional loading; (2) multiple variations in symptom self-management; (3) barriers to symptom self-management: limited access to information resources, insufficient awareness and skills in symptom self-management, lack of economic and social support, and difficulties in medical visits and reviews; and (4) facilitators of symptom self-management: perceived benefits, experience-driven, and peer experiences.</p></div><div><h3>Conclusion</h3><p>Patients undergoing hematopoietic stem cell transplantation experience multiple and complex symptom experiences after hospital discharge, and their symptom self-management remains challenging. The findings underscore the necessity for healthcare professionals to regularly and consistently evaluate the symptoms and self-management practices of patients undergoing hematopoietic stem cell transplantation and execute focused interventions to alleviate their symptom load and enhance their long-term well-being.</p></div>","PeriodicalId":51048,"journal":{"name":"European Journal of Oncology Nursing","volume":null,"pages":null},"PeriodicalIF":2.7,"publicationDate":"2024-07-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141702633","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effects of online mindful self-compassion intervention on negative body image in breast cancer patients: A randomized controlled trail","authors":"","doi":"10.1016/j.ejon.2024.102664","DOIUrl":"10.1016/j.ejon.2024.102664","url":null,"abstract":"<div><h3>Purpose</h3><p>The incidence of breast cancer patients with negative body image has increased. However, research on interventions that explicitly reduce negative body image among breast cancer patients remains inadequate. The development of more pragmatic interventions is imperative. Therefore, we conducted this study to assess the effectiveness of a 6-week online Mindful Self-Compassion (MSC) intervention to reduce the negative body image in breast cancer patients.</p></div><div><h3>Methods</h3><p>We randomly assigned 64 female breast cancer patients to either the MSC group or the control group. The MSC group received a 6-week online Mindful Self-Compassion intervention, while the control group received no psychological training. Participants were surveyed by the Self-Compassion Scale-Short Form (SCS-SF), the Self-Acceptance Questionnaire (SAQ), the Chinese Perceived Stress Scale (CPSS), and the Body Image Scale (BIS) at baseline (T1), post-intervention (T2), and 1-month follow-up (T3).</p></div><div><h3>Results</h3><p>All outcome variables demonstrated significant time main effects and nonsignificant group main effects. The MSC and control groups had significant time × group interaction effects on self-compassion, self-acceptance, perceived stress, and negative body image. Simple main effects analysis revealed significant improvements in outcome variables at three-time points for the MSC group.</p></div><div><h3>Conclusion</h3><p>A 6-week online Mindful Self-Compassion intervention can improve self-compassion and self-acceptance and reduce perceived stress and negative body image among the breast cancer patients in MSC group. Mindful Self-Compassion intervention shows promise as a viable way to maintain the mental well-being of breast cancer patients.</p></div>","PeriodicalId":51048,"journal":{"name":"European Journal of Oncology Nursing","volume":null,"pages":null},"PeriodicalIF":2.7,"publicationDate":"2024-07-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141690596","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Recognizing and acknowledging end-of-life for patients with cancer - a balancing act. A qualitative study of doctors' and nurses' experiences","authors":"Gry Ciekals Wallgren ,&nbsp;Janet Bakken ,&nbsp;Bodil Furnes ,&nbsp;Hartwig Kørner ,&nbsp;Venke Ueland","doi":"10.1016/j.ejon.2024.102654","DOIUrl":"https://doi.org/10.1016/j.ejon.2024.102654","url":null,"abstract":"<div><h3>Purpose</h3><p>Doctors and nurses are central in the challenging task of end-of-life (EOL) care, and this study aims to explore and describe doctors' and nurses' experiences of recognition and acknowledgment of the end of life for patients with cancer.</p></div><div><h3>Methods</h3><p>A qualitative, explorative research design with individual interviews was carried out based on a semi-open interview guide. A total of 6 doctors and 6 nurses working in medical or surgical departments at a Norwegian University hospital were interviewed. The interviews were analyzed using qualitative content analysis.</p></div><div><h3>Results</h3><p>The study’s findings highlight that recognizing and acknowledging patients with cancer as being at end-of-life is a challenging process. Three subthemes emerged from the analysis; <em>the significance of being experienced</em>, <em>the significance of organizational structures,</em> and <em>the significance of having a common understanding.</em> A main theme was analyzed further and abstracted from the subthemes<em>; Being safe to manage the balancing act of recognizing and acknowledging the end of life.</em></p></div><div><h3>Conclusions</h3><p>Much is at stake in the EOL setting, and healthcare professionals (HCP) must balance several aspects regarding EOL decisions. Striking the right balance in these situations is challenging. HCPs need a <em>safety net</em> through collaboration with, and support from, colleagues, supporting organizational structures and experience. Strengthening the <em>safety net</em> will have a clear impact on improving clinical practice to reduce futile treatment and provide high-quality EOL care for all dying patients in hospitals.</p></div>","PeriodicalId":51048,"journal":{"name":"European Journal of Oncology Nursing","volume":null,"pages":null},"PeriodicalIF":2.7,"publicationDate":"2024-07-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1462388924001522/pdfft?md5=c840d77625360e2eea279c35feec756b&pid=1-s2.0-S1462388924001522-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141605799","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A study of the relationship and mediating effects of perceived stress and post-traumatic growth in patients undergoing postoperative chemotherapy for breast cancer","authors":"Xiao Wan ,&nbsp;Yiqiu Zhang ,&nbsp;Qianwen Peng ,&nbsp;Yiming Zhang ,&nbsp;Guangli Lu ,&nbsp;Shejuan Liu ,&nbsp;Chaoran Chen","doi":"10.1016/j.ejon.2024.102659","DOIUrl":"https://doi.org/10.1016/j.ejon.2024.102659","url":null,"abstract":"<div><h3>Objective</h3><p>The traumatic experience of cancer, in addition to its negative impact on breast cancer patients, can also bring about positive change, i.e., post-traumatic growth (PTG). PTG can help boost patients’ confidence in their fight against the disease and improve their adherence to treatment, thereby facilitating their recovery. The study aimed to investigate the effect of perceived stress on the PTG of patients undergoing postoperative chemotherapy for breast cancer and to examine the roles of rumination and self-efficacy between two.</p></div><div><h3>Methods</h3><p>The data was collected using a cross-sectional design. From December 2021 to October 2022, a total of 306 breast cancer patients who had undergone chemotherapy following surgery and met the inclusion and exclusion criteria were selected from three tertiary-level A hospitals in Henan Province, China. We conducted descriptive analysis, Pearson correlation analysis, and a regression analysis using PROCESS Macro Model 80 to explore the relationships among perceived stress, rumination, self-efficacy, and PTG.</p></div><div><h3>Results</h3><p>Perceived stress of patients undergoing postoperative chemotherapy for breast cancer had a negative predictive effect on PTG (<em>r</em> = −0.340, <em>P</em> &lt; 0.01); Rumination and self-efficacy played a partial mediating effect between perceived stress and PTG, accounting for 45.25% of the total effect.</p></div><div><h3>Conclusions</h3><p>Clinical nursing staff could promote PTG by strengthening psychological assessment and timely psychological intervention for patients with high perceived stress levels, encourage patients to adopt a positive way of thinking about illness and improve their self-efficacy level, so as to improve their PTG level.</p></div>","PeriodicalId":51048,"journal":{"name":"European Journal of Oncology Nursing","volume":null,"pages":null},"PeriodicalIF":2.7,"publicationDate":"2024-07-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141605797","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The association between patient characteristics, psychological distress, and coping in the diagnostic phase of prostate cancer – A cross-sectional multicenter study","authors":"Maja Elisabeth Juul Søndergaard ,&nbsp;Kirsten Lode ,&nbsp;Sissel Eikeland Husebø ,&nbsp;Ingvild Dalen ,&nbsp;Svein Reidar Kjosavik","doi":"10.1016/j.ejon.2024.102658","DOIUrl":"https://doi.org/10.1016/j.ejon.2024.102658","url":null,"abstract":"<div><h3>Purpose</h3><p>This study aims to investigate the associations between patient characteristics, psychological distress, and coping in the diagnostic phase of prostate cancer.</p></div><div><h3>Methods</h3><p>A cross-sectional multicentre study was conducted from 2017 to 2019. A total of 250 patients were recruited from three hospitals in western Norway. The patients completed a questionnaire while awaiting their prostate biopsy. Patient characteristics were collected, and the Hospital Anxiety and Depression Scale and the Revised Ways of Coping Checklist were used to measure psychological distress and evaluate coping strategies and primary appraisal, respectively.</p></div><div><h3>Results</h3><p>Approximately 15% and 5% of the patients experienced symptoms of anxiety and depression, respectively. Younger age and poorer self-reported health were associated with higher anxiety levels. Anxiety was associated with all five coping strategies but showed the strongest correlation with wishful thinking. The patients who appraised their situation as a threat experienced more symptoms of both anxiety and depression and used more wishful thinking and avoidance than did the patients who appraised their situation as a challenge or benign.</p></div><div><h3>Conclusion</h3><p>A subgroup of patients experiences psychological distress during diagnostic evaluation of prostate cancer. Age, self-reported health, and primary appraisal may contribute to the development of psychological distress. Identification of patient characteristics associated with higher levels of psychological distress may guide nurses in implementing early interventions aimed at supporting beneficial coping and enhancing well-being.</p></div>","PeriodicalId":51048,"journal":{"name":"European Journal of Oncology Nursing","volume":null,"pages":null},"PeriodicalIF":2.7,"publicationDate":"2024-07-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S146238892400156X/pdfft?md5=79cc72665aa0bce87a5a80c64f2116b2&pid=1-s2.0-S146238892400156X-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141605464","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Symptom network and quality of life of breast cancer patients receiving multimodal cancer treatment: Cross-sectional study","authors":"Yong Bae Kim ,&nbsp;Ik Jae Lee ,&nbsp;Hwa Kyung Byun ,&nbsp;Yun Young Choi ,&nbsp;Bomi Hong ,&nbsp;Jiyeon Lee","doi":"10.1016/j.ejon.2024.102661","DOIUrl":"10.1016/j.ejon.2024.102661","url":null,"abstract":"<div><h3>Purpose</h3><p>Breast cancer patients experience symptoms and side effects from multimodal treatments, which often include menopausal symptoms resulting from cytotoxic chemotherapy or estrogen suppression therapy. This study aimed to explore the symptom network and clusters and its relationship to quality of life (QoL) in breast cancer patients who receive multimodal cancer treatment and experience treatment-related menopausal symptoms.</p></div><div><h3>Methods</h3><p>A correlational study was conducted. Breast cancer patients receiving multimodal cancer treatment and experiencing treatment-related menopausal symptoms were included while they were receiving radiation therapy (N = 250). Symptoms, functions and QoL were assessed using the EORTC QLQ-C30 and BR45. Network analysis, principal component analysis, exploratory factor analysis, and multiple linear regression analysis were conducted.</p></div><div><h3>Results</h3><p>Fatigue was the most central symptom in the symptom-only network as well as in the network consisting of symptoms and QoL. Fatigue, systemic therapy side effects, appetite loss, and cognitive symptoms demonstrated significant associations with QoL. The cancer and treatment related symptom cluster consisted of fatigue, cognitive symptoms, emotional symptoms and systemic therapy side effects. Breast cancer therapy-specific symptoms, such as arm symptoms, skin mucosis symptoms, and breast symptoms, formed a cluster with pain.</p></div><div><h3>Conclusion</h3><p>Fatigue was the most central symptom in breast cancer patients receiving multimodal cancer treatment and experiencing menopausal symptoms. Evaluation of fatigue and providing interventions to manage fatigue would contribute to improvement of QoL of breast cancer patients receiving multimodal cancer treatments. Future network analysis and symptom cluster studies should specify the population of interest and the treatment phase using comprehensive symptom evaluation tools.</p></div>","PeriodicalId":51048,"journal":{"name":"European Journal of Oncology Nursing","volume":null,"pages":null},"PeriodicalIF":2.7,"publicationDate":"2024-07-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141604450","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Effect of Pushing Technique with Normal Saline on Peripheral Intravenous Catheter Placement Success: A Randomized Controlled Trial","authors":"Meltem GÜRCAN ,&nbsp;Nimet KARATAŞ ,&nbsp;Ayla KAYA ,&nbsp;Sevcan ATAY. TURAN ,&nbsp;Elif GÜLER","doi":"10.1016/j.ejon.2024.102656","DOIUrl":"10.1016/j.ejon.2024.102656","url":null,"abstract":"<div><h3>Purpose</h3><p>The aim of the present study is to determine the effect of the pushing technique with saline on the success of peripheral IV catheter placement in a paediatric haematology and oncology sample.</p></div><div><h3>Methods</h3><p>The randomized controlled trial was conducted among 60 paediatric haematology and oncology patients aged between 0 and 17. The participants were randomly assigned to two peripheral intravenous catheter placement groups (intervention group, n:30, control group, n:30). Each patient was evaluated with the Difficult Intravenous Access (DIVA) score before being included in the study. Each patient was assessed using the Personal Information Form for Children and Catheter Registration Form.</p></div><div><h3>Results</h3><p>The average age of the children was 86.4 months (SD = 60.0); 36.7% were female. The pushing technique with saline significantly increased the success of placing a peripheral IV catheter on the first attempt in the intervention group compared to the control group (F=42.391, p=0.000). The number of attempts during peripheral IV catheter placement significantly decreased in the intervention group compared with the control group (t=-5.676, p=0.000). Complications were less in the intervention group compared with the control group (χ2=24.438, p=0.000). The procedure time was significantly shorter in the intervention group compared with the control group (t=-4.026, p=0.000).</p></div><div><h3>Conclusion</h3><p>The pushing technique with saline is an effective method to increase the first attempt success rate, decrease the number of attempts, reduce the procedure time, and reduce the complications during peripheral intravenous catheter placement procedures in paediatric haematology and oncology patients with difficult intravenous access.</p></div>","PeriodicalId":51048,"journal":{"name":"European Journal of Oncology Nursing","volume":null,"pages":null},"PeriodicalIF":2.7,"publicationDate":"2024-07-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141604451","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of oral health education on improving knowledge, attitude, practice, and oral health status of patients with liver cancer: A quasi-experimental study","authors":"Yue Tao ,&nbsp;Yan Zhang ,&nbsp;Jie Chen ,&nbsp;Leisheng Wang ,&nbsp;Na Zhu ,&nbsp;Hao Hu","doi":"10.1016/j.ejon.2024.102660","DOIUrl":"10.1016/j.ejon.2024.102660","url":null,"abstract":"<div><h3>Purpose</h3><p>To evaluate the effectiveness of the PRECEDE-PROCEED model (PPM) in helping patients with liver cancer be aware of their knowledge, skills, and abilities in self-oral health behaviors and improve their oral health status.</p></div><div><h3>Methods</h3><p>This is a quasi-experimental study of 90 patients with liver cancer assigned to an oral health education or a control group. The intervention group was educated with the PRECEDE-PROCEED model. A brief oral scale and the knowledge, attitude, and practice oral health questionnaire were employed to measure the oral health status and cognitive behavioral ability to seek oral health in patients.</p></div><div><h3>Results</h3><p>Among 102 eligible patients, 90 (88.23%) agreed to participate in the present study and were divided to intervention (n = 45) or control (n = 45) groups. After the intervention and one month after discharge, the oral health scores of patients in the Intervention group were lower than those of the control group (<em>P</em> &lt; 0.05). In addition, after the intervention and one month after discharge, the patients in the test group had higher scores on knowledge, beliefs, and behaviors of oral health than the control group (<em>P</em> &lt; 0.05). One month after discharge, the mean knowledge and skills scores were significantly higher in the intervention group than in the control group.</p></div><div><h3>Conclusions</h3><p>Our findings suggest that oral health education may be a useful health intervention for patients with liver cancer. It may also improve the knowledge and beliefs of liver cancer patients seeking oral health. Larger long-term investigations are necessary to provide more support for these preliminary conclusions.</p></div>","PeriodicalId":51048,"journal":{"name":"European Journal of Oncology Nursing","volume":null,"pages":null},"PeriodicalIF":2.7,"publicationDate":"2024-07-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1462388924001583/pdfft?md5=72cc9935b04ba95363b13422bbcd2531&pid=1-s2.0-S1462388924001583-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141538901","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The effect of a hybrid structured pulmonary rehabilitation education program for patients with lung cancer with a high risk of postoperative pulmonary complications: A quasi-experimental study","authors":"Yan Liang ,&nbsp;Ting Deng ,&nbsp;Yangyang Long ,&nbsp;Jin Li ,&nbsp;Jinfen Yang ,&nbsp;Yufan Hu ,&nbsp;Taiping Lu ,&nbsp;Xu Luo ,&nbsp;Lorna Kwai Ping Suen ,&nbsp;Shaolin Chen","doi":"10.1016/j.ejon.2024.102655","DOIUrl":"10.1016/j.ejon.2024.102655","url":null,"abstract":"<div><h3>Purpose</h3><p>The absence of standardized protocols and education are the main obstacles to perioperative pulmonary rehabilitation (PR), especially for patients with high-risk factors of postoperative pulmonary complications (PPCs). We aimed to explore the effect of a hybrid structured pulmonary rehabilitation education program (SPREP) on patients with lung cancer at high risk of PPCs.</p></div><div><h3>Methods</h3><p>A quasi-experimental trial with a pre-post test design was conducted. The control group (n = 53) adopted routine perioperative pulmonary rehabilitation, while the intervention group (n = 53) received SPREP. Respiratory function, 6-min walk distance, Borg dyspnea scale, quality of life, anxiety–depression scores at admission, discharge, 2 weeks and 3 months post-discharge, and incidence of PPCs were compared between the two groups.</p></div><div><h3>Results</h3><p>There were no significant differences on the 6-min walk distance and Borg Dyspnoea Scale at discharge between the two groups (<em>P</em> &gt; 0.05), whereas the intervention group showed improved performance at the remaining time points (<em>P</em> &lt; 0.05). In addition, the intervention group had improved exercise capacity, pulmonary function and quality of life, reduced levels of anxiety and depression at discharge, 2 weeks post-discharge and 3 months post-discharge (<em>P</em> &lt; 0.05). In addition, incidence of PPCs was significantly reduced in the intervention group, especially postoperative pneumonia.</p></div><div><h3>Conclusions</h3><p>The SPREP could show significant benefits in enhancing exercise capacity, lung function, and quality of life, while diminishing the occurrence of PPCs and mitigating the levels of anxiety and depression, future large RCT need to further explore the efficacy.</p></div><div><h3>Trial registration</h3><p>This study was registered with the China Clinical Trial Registration Center (ChiCTR) under the Clinical Trial Registration Number [ChiCTR2200066698].</p></div>","PeriodicalId":51048,"journal":{"name":"European Journal of Oncology Nursing","volume":null,"pages":null},"PeriodicalIF":2.7,"publicationDate":"2024-07-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141538902","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Factors associated with cancer-related cognitive impairment in patients with lung cancer: A systematic review","authors":"Tianxue Hou ,&nbsp;Wenting Peng ,&nbsp;Mu-Hsing Ho ,&nbsp;Naomi Takemura ,&nbsp;Chia-Chin Lin","doi":"10.1016/j.ejon.2024.102657","DOIUrl":"10.1016/j.ejon.2024.102657","url":null,"abstract":"<div><h3>Purpose</h3><p>Cognitive impairment is common in lung cancer patients and impacts their quality of life. Little is known about the etiology of cognitive impairment in lung cancer patients. However, the associated factors of cognitive impairment among lung cancer patients have not been systematically reviewed. This review aimed to summarize the factors related to cognitive impairment among lung cancer patients.</p></div><div><h3>Methods</h3><p>PubMed, EMBASE, PsycINFO, CINAHL Plus, and Web of Science were searched to retrieve articles published from data inception until January 21, 2024, focusing on factors associated with cognitive impairment among lung cancer patients. Critical appraisal was undertaken by two reviewers independently using the Newcastle–Ottawa Scale.</p></div><div><h3>Results</h3><p>A total of 17 observational studies were included. The results showed that 20 factors are associated with cognitive impairment, including psychological factors (loneliness, fatigue, anxiety, depression, high symptom burden, and baseline cognitive impairment), lifestyle and functional factors (daily step counts, smoking, and activities of daily living or instrumental activities of daily living impairments), medical treatment factors (cranial irradiation, chemotherapy, lobar resection, postoperative delirium, and on medication), and neuroimmunological factors (have neuronal autoantibodies, altered Default Mode Network connectivity, dysregulation in glutamate and glutamate metabolism, mitochondrial dysfunction, blood-brain barrier leakage, and reduced T-lymphocytes).</p></div><div><h3>Conclusion</h3><p>This is the first study to systematically review 20 factors associated with cognitive impairment among lung cancer patients, encompassing psychology, lifestyle and functional, medical treatment, and neuroimmunological factors. These findings can help clinicians identify at-risk patients and develop evidence-based interventions to prevent cognitive impairment among lung cancer patients.</p></div>","PeriodicalId":51048,"journal":{"name":"European Journal of Oncology Nursing","volume":null,"pages":null},"PeriodicalIF":2.7,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141499545","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}