European Journal of Oncology Nursing最新文献

{"title":"Mindfulness-integrated Cognitive Behavioral Therapy reduces pain and psychological distress, and improves equanimity, hope and post-traumatic growth during breast cancer treatment: A pilot randomized controlled trial","authors":"Mohsen Arefian ,&nbsp;Karim Asgari-Mobarake","doi":"10.1016/j.ejon.2025.102881","DOIUrl":"10.1016/j.ejon.2025.102881","url":null,"abstract":"<div><h3>Purpose</h3><div>The objective of this study was to evaluate the effectiveness of a shortened version of Mindfulness-integrated Cognitive Behavior Therapy (MiCBT) in managing pain and psychological distress (including depression, anxiety, and stress), improving equanimity, hope, and post-traumatic growth in patients with Stage I-III breast cancer undergoing chemotherapy.</div></div><div><h3>Methods</h3><div>A total of 42 women were randomly assigned to either an intervention group (n = 21) or a treatment-as-usual (TAU) (n = 21). All participants completed a battery of assessments for pain, emotional distress, hope, equanimity, and post-traumatic growth before and after the intervention, as well as at the 2-month follow-up. The intervention consisted of a short (4-week) MiCBT program, which involved progressive muscle relaxation, mindfulness of breath, body scanning, and the mindfulness-based interoceptive exposure task (MIET) for pain. The program was conducted over four consecutive weeks.</div></div><div><h3>Results</h3><div>Compared with the TAU group, at post-treatment, the MiCBT group experienced larger and significant reductions in pain (<em>d</em> = 1.58), psychological distress (<em>d</em> = .99), depression (<em>d</em> = 1.59), anxiety (<em>d</em> = 1.13), and stress (<em>d</em> = 1.68), as well as improvements in equanimity (d = 1.61), hope (<em>d</em> = 1.06), and post-traumatic growth (<em>d</em> = .6) (<em>p's</em> &lt; .5). These differences remained significant at 2-month follow-up.</div></div><div><h3>Conclusion</h3><div>This study provides preliminary evidence that a four-week MiCBT intervention can improve the daily experiences of women with BC undergoing chemotherapy. Further research using larger samples and active control is needed to determine the generalizability of the results.</div></div>","PeriodicalId":51048,"journal":{"name":"European Journal of Oncology Nursing","volume":"76 ","pages":"Article 102881"},"PeriodicalIF":2.7,"publicationDate":"2025-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143759769","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The effect of an interactive nurse support program developed with a mobile application on patient outcomes in breast cancer patients who received outpatient chemotherapy: A randomized controlled trial","authors":"Handan Özdemir ,&nbsp;Ayten Demir ,&nbsp;Murat Bardakçı ,&nbsp;Doğan Uncu","doi":"10.1016/j.ejon.2025.102882","DOIUrl":"10.1016/j.ejon.2025.102882","url":null,"abstract":"<div><h3>Purpose</h3><div>To determine the effect of the interactive nurse support program developed with a mobile application on patient outcomes (symptom management, quality of life, perception of social support, anxiety) in breast cancer patients who received outpatient chemotherapy.</div></div><div><h3>Methods</h3><div>The randomized controlled study was conducted in the outpatient chemotherapy unit of a public hospital between 2021 and 2023. The study sample consisted of 100 breast cancer patients receiving anthracycline-cyclophoshamide chemotherapy. Patients in the control group received standard care, and patients in the intervention group were applied an interactive nurse support program developed with a mobile application throughout four chemotherapy cycles. Memorial Symptom Assessment Scale (MSAS), EORTC QLQ-C30, EORTC QLQ-BR23 Scales, Multidimensional Perceived Social Support Scale (MPSSS), Beck Anxiety Scale (BAS) were used in data collection. Data were collected five times, including before chemotherapy (t₀) and at the end of the first week after each chemotherapy (t₁, t₂, t₃, t₄).</div></div><div><h3>Results</h3><div>MSAS, BAS total scores, EORTC QLQ-C30 and EORTC QLQ-BR23 Scales “Symptom Dimension” scores of the patients in the intervention group were found to be significantly lower than the control group at t₁, t₂, t₃, t₄ (p˂0.05). EORTC QLQ-C30 Scale “General Well-Being”, “Functional Status”, EORTC QLQ-BR23 “Functional Status” scores, MPSSS total scores of the patients in the intervention group were found to be significantly higher than the control group at t₁, t₂, t₃, t₄ measurements (p˂0.05).</div></div><div><h3>Conclusions</h3><div>The interactive nurse support program developed with the mobile application is effective on patient outcomes in breast cancer patients who received outpatient chemotherapy.</div></div><div><h3>Trial registration</h3><div><span><span>www.clinicaltrials.gov</span><svg><path></path></svg></span><em>, NCT05739175.</em></div></div>","PeriodicalId":51048,"journal":{"name":"European Journal of Oncology Nursing","volume":"76 ","pages":"Article 102882"},"PeriodicalIF":2.7,"publicationDate":"2025-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143767937","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Self-management behaviors in patients undergoing radical prostatectomy: A structural equation model","authors":"Jieru Zhou,&nbsp;Yongcai Liu,&nbsp;Yijuan Huang,&nbsp;Xin Yao,&nbsp;Jian Cai,&nbsp;Haihong Jiang,&nbsp;Xiangxiang Ye,&nbsp;Wei Chen ,&nbsp;Haiyan Li","doi":"10.1016/j.ejon.2025.102879","DOIUrl":"10.1016/j.ejon.2025.102879","url":null,"abstract":"<div><h3>Purpose</h3><div>To investigate factors influencing self-management behaviors in post-radical prostate cancer patients' behaviors grounded on the Integrated Theory of Health Behaviour Change and to clarify the interactions among these factors.</div></div><div><h3>Methods</h3><div>In a cross-sectional study, 281 patients were recruited at The First Hospital of Wenzhou Medical University in China between December 2023 and April 2024. Illness perception, social support, self-regulation and self-management were assessed through Chinese versions of the Brief Illness Perception Questionnaire (BIPQ), Medical Outcome Study Social Support Survey-Chinese (MOS-SSS-C), Treatment Self-regulation Questionnaire (TSRQ) and The Cancer Patient Self-management Assessment Scale. Structural equations were used to explore the relationship between the four variables.</div></div><div><h3>Results</h3><div>The final structural model using the Integrated Theory of Health Behaviour Change showed a suitable fit (RMSEA = 0.073, CMIN/DF = 2.482). Illness perception directly affected self-management (β = −0.416, P &lt; 0.05) and indirectly affected self-management through self-regulation (β = 0.269, P &lt; 0.05). Self-regulation directly affected self-management (β = 0.453, P &lt; 0.05). Social support indirectly affected self-management (β = 0.225, P &lt; 0.05). These variables contributed to 62.9 % of the variability in self-management behaviors among patients after radical prostate cancer treatment.</div></div><div><h3>Conclusions</h3><div>The present study suggested a model can be useful in better understanding self-management in post-radical prostate cancer patients. Besides, these patients experience bad self-management. Illness perception and social support can affect post-radical prostate cancer patients' self-management directly and indirectly through self-regulation.</div></div>","PeriodicalId":51048,"journal":{"name":"European Journal of Oncology Nursing","volume":"76 ","pages":"Article 102879"},"PeriodicalIF":2.7,"publicationDate":"2025-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143791989","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Families' experience of anticipatory grief in home-based palliative cancer care and their support needs: A qualitative study","authors":"Kristina Svop (Clinical Nursing Specialist) ,&nbsp;Karin Brochstedt Dieperink (Deputy Head, Professor in Cancer & Family Care) ,&nbsp;Trish Livingston (Professor) ,&nbsp;Jette Marcussen (Associate Professor)","doi":"10.1016/j.ejon.2025.102880","DOIUrl":"10.1016/j.ejon.2025.102880","url":null,"abstract":"<div><h3>Purpose</h3><div>The aim of this study was to investigate how families of patients with cancer in palliative care experience anticipatory grief and their expressed support needs in relation to loss and grief.</div></div><div><h3>Method</h3><div>The study applied a qualitative hermeneutic-phenomenology framework. Qualitative data were obtained through semi-structured family interviews with five families living in a municipality in Denmark. The interviews were audiotaped, transcribed and analyzed using a thematical analytical approach.</div></div><div><h3>Results</h3><div>Three major themes were identified (1) <em>anticipatory grief constantly present in everyday life.</em> Anticipatory grief occurred when families watched the illness progress, and they experienced physical, cognitive and relational losses both with the patient and within family. (2) <em>Experience of</em> support <em>from both family and professionals.</em> (3) <em>Families change perception when illness is present in daily life.</em> Families experienced loss as a dynamic process oscillating between living their everyday life and feeling the presence of illness.</div></div><div><h3>Conclusion</h3><div>The study highlighted family's anticipatory grief is not addressed sufficiently in palliative care. Anticipatory grief occurred when families watched the illness progress, and they experienced physical, cognitive and relational losses both with the patient and within the family. Clinical interventions, such as a <em>model for family interventions during anticipatory grief,</em> are required to address different palliative care trajectories and reduce anticipatory grief in families.</div></div>","PeriodicalId":51048,"journal":{"name":"European Journal of Oncology Nursing","volume":"76 ","pages":"Article 102880"},"PeriodicalIF":2.7,"publicationDate":"2025-03-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143767941","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A phenomenological study of the cultural lived experiences among Angolan women with breast cancer","authors":"Naira Sousa-Martins ,&nbsp;Luís Azevedo ,&nbsp;Lygia Vieira Lopes ,&nbsp;Maria do Céu Barbieri-Figueiredo","doi":"10.1016/j.ejon.2025.102885","DOIUrl":"10.1016/j.ejon.2025.102885","url":null,"abstract":"<div><h3>Purpose</h3><div>This study aims to explore and describe the lived experiences of Angolan women with breast cancer, considering the socio-cultural context and health care challenges they face.</div></div><div><h3>Method</h3><div>Eighteen semi-structured interviews were conducted among Angolan women with breast cancer. Purposeful sampling was utilised to select participants with diverse age groups and ethnic backgrounds. We performed a qualitative study using Giorgi's descriptive phenomenological approach.</div></div><div><h3>Results</h3><div>The present study found cultural views of breast cancer, family support, and religious-spiritual coping to be essential themes. The results offer significant insights into the cultural framework of health in Angolan society, encompassing the information, perceptions, and cognitions employed to describe, comprehend, and elucidate illness, as well as the pursuit of therapy that seldom aligns biological criteria.</div></div><div><h3>Conclusions</h3><div>The present study has implications for nursing, as it recognises that individuals have unique behaviours and thoughts related to their current understanding of the illness, their personal experience with the illness, and their specific beliefs about health and healing.</div><div>The findings of this study provide essential insights into how Angolan women's cultural beliefs and practices shape their experiences with breast cancer, offering nurses a foundation to develop culturally competent care approaches.</div></div>","PeriodicalId":51048,"journal":{"name":"European Journal of Oncology Nursing","volume":"76 ","pages":"Article 102885"},"PeriodicalIF":2.7,"publicationDate":"2025-03-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143747285","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Heterogeneity of depression trajectories and associated risk factors during radiotherapy in patients with gastrointestinal cancer: A longitudinal study","authors":"Ke Wang ,&nbsp;Mengjia Liu ,&nbsp;Lin Yang ,&nbsp;Hong Li ,&nbsp;Yaxin Chang ,&nbsp;Min Diao ,&nbsp;Jordan Tovera Salvador ,&nbsp;Zhaoxia Yang","doi":"10.1016/j.ejon.2025.102886","DOIUrl":"10.1016/j.ejon.2025.102886","url":null,"abstract":"<div><h3>Purpose</h3><div>To identify the heterogeneity in depression trajectories and factors influencing depression during radiotherapy in patients with gastrointestinal cancer.</div></div><div><h3>Methods</h3><div>Between August 2023 and May 2024, we longitudinally tracked the symptoms of 146 patients with gastrointestinal cancer at T0 (pre-radiotherapy), T1 (mid-radiotherapy), and T2 (1-month post-radiotherapy). Group-based trajectory models were used to identify subgroups of depression trajectories. A fit-criteria assessment plot was used to assess the accuracy of grouping, and univariate and multivariate logistic regression models were used to analyze the potential independent factors associated with the subgroups.</div></div><div><h3>Results</h3><div>Patients were categorized into three subgroups: no depression (31.5 %), mild depression (54.1 %), and moderate depression (14.4 %) group. Patients aged &gt;65 years (<em>P</em> &lt; 0.05), those with a malnutrition-inflammation complex (<em>P</em> &lt; 0.05), and those accompanied by children (<em>P</em> &lt; 0.05) were more likely to belong to the moderate depression group. Between-group and within-group differences in psychoneurologic symptoms, such as fatigue, remained consistent with depression. Depressive symptoms were most severe mid-radiotherapy, and moderately depressed patients were at risk of developing major depression.</div></div><div><h3>Conclusions</h3><div>There was significant heterogeneity in depression during radiotherapy among patients with gastrointestinal cancer. Clinicians should focus on identifying high-risk patients with depression aged &gt;65 years, those with a malnutrition-inflammation complex, and those accompanied by children. They should actively implement pharmacological and non-pharmacological treatments and refer them to specialized psychological clinics, if necessary, to prevent the occurrence of major depression.</div></div>","PeriodicalId":51048,"journal":{"name":"European Journal of Oncology Nursing","volume":"76 ","pages":"Article 102886"},"PeriodicalIF":2.7,"publicationDate":"2025-03-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143767940","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Factors influencing advance care planning among cancer patients: A qualitative study","authors":"Yin Yan ,&nbsp;Tan Derong ,&nbsp;Tong Qin ,&nbsp;Xu Zhi ,&nbsp;Liu Xia","doi":"10.1016/j.ejon.2025.102884","DOIUrl":"10.1016/j.ejon.2025.102884","url":null,"abstract":"<div><h3>Purpose</h3><div>The study aims to explore the factors influencing advance care planning among cancer patients, recognizing the importance of understanding these factors to enhance patient outcomes and ensure that patients' preferences are honored.</div></div><div><h3>Methods</h3><div>Conducted from May to November 2023, this qualitative descriptive study employed a phenomenological research approach. In-depth face-to-face interviews and observations were utilized to gather insights into the factors influencing participation in advance care planning, guided by a semi-structured interview outline based on social ecosystem theory. Content analysis and thematic analysis were applied to identify and interpret key themes from the data.</div></div><div><h3>Results</h3><div>A total of 17 cancer patients participated in the interviews. The analysis revealed four main themes. Facilitating factors included optimistic health views and positive attitudes toward advance care planning, which encouraged engagement. Conversely, barriers such as a lack of understanding of advance care planning, misconceptions, and negative attitudes hindered participation. Family dynamics played a significant role; trust in family decisions facilitated discussions, while family pressure created challenges. Economic burdens and cultural taboos surrounding death, along with reliance on healthcare providers, impeded open conversations. These findings highlight the necessity for targeted strategies to enhance patient involvement in advance care planning.</div></div><div><h3>Conclusion</h3><div>Cancer patients' advance care planning is influenced by positive factors like optimistic health views and supportive family dynamics, as well as obstacles such as misconceptions, cultural taboos, and economic burdens. Targeted interventions are needed to empower patients and better align care with their values.</div></div>","PeriodicalId":51048,"journal":{"name":"European Journal of Oncology Nursing","volume":"76 ","pages":"Article 102884"},"PeriodicalIF":2.7,"publicationDate":"2025-03-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143759846","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Divergent perspectives: A cross-sectional study unveiling disparities in cancer patients' and oncology nurses' perceptions on communication and empathy","authors":"Che-Ming Chang ,&nbsp;Jhen-Jhen Li ,&nbsp;In-Fun Li ,&nbsp;Yun-Hsiang Lee","doi":"10.1016/j.ejon.2025.102877","DOIUrl":"10.1016/j.ejon.2025.102877","url":null,"abstract":"<div><h3>Purpose</h3><div>To examine the relationship between cancer patients' perceptions and oncology nurses' self-assessments of communication skills and empathy, and investigate the influence of patients' factors on these perceptions.</div></div><div><h3>Methods</h3><div>This cross-sectional study used a paired sampling approach (1:2 ratio) with 168 oncology nurses and 336 cancer patients. It assessed patients' perceptions and nurses' self-assessments of nurse-expressed communication and empathy. The study examined the relationship with patients' demographic (age, gender, education level, occupational status, and marital status), clinical (length of hospital stay and physical functional status), and psychosocial factors (religious beliefs and presence of family caregiver).</div></div><div><h3>Results</h3><div>Patients reported moderate levels of communication (Mean [M] = 54.73, Standard deviation [SD] = 8.97) and empathy (M = 21.94, SD = 6.93). No significant correlation was found between patients' and nurses' perceptions of communication (r = −.041, p = .362) and empathy (r = −.014, p = .419). Lower patient-perceived communication and empathy were associated with higher education level, poor physical functional status, longer hospital stays (&gt;15 days), being unmarried, and absence of family caregivers (only in communication perception) (all p &lt; .05).</div></div><div><h3>Conclusion</h3><div>Cancer patients' and oncology nurses' perceptions of communication and empathy were not significantly correlated. Length of hospital stay, physical functional status, marital status, presence of family caregivers, and education level significantly influenced patients' perceptions. Future interventions should focus on vulnerable groups and adapting to patients' changing needs during extended hospital stays.</div></div>","PeriodicalId":51048,"journal":{"name":"European Journal of Oncology Nursing","volume":"76 ","pages":"Article 102877"},"PeriodicalIF":2.7,"publicationDate":"2025-03-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143777215","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Coping with the unthinkable: A qualitative metasynthesis of patients’ experiences with incurable cancer","authors":"Anu Viitala ,&nbsp;Mira Palonen ,&nbsp;Juho T. Lehto ,&nbsp;Päivi Åstedt-Kurki","doi":"10.1016/j.ejon.2025.102876","DOIUrl":"10.1016/j.ejon.2025.102876","url":null,"abstract":"<div><h3>Purpose</h3><div>This study aimed to address the coping experiences of adult patients with incurable cancer palliative and hospice care. The objective of the study was to provide information that can help improve their support.</div></div><div><h3>Methods</h3><div>The study used a qualitative research design, including a literature review and semi-structured interviews with 56 adult patients. Data were analyzed using inductive content analysis and metasynthesis.</div></div><div><h3>Results</h3><div>Key coping factors identified were managing everyday life, maintaining the best possible health, utilizing support options, and accepting the incurable nature of their disease. Emotional coping and inconsistencies in the healthcare support network also played significant roles.</div></div><div><h3>Conclusions</h3><div>The study highlighted the coping experiences, expectations, and problems faced by patients with incurable cancer, aiming to make their needs more visible in public healthcare. The findings can help healthcare sectors design better services and support for these patients and their families.</div></div>","PeriodicalId":51048,"journal":{"name":"European Journal of Oncology Nursing","volume":"76 ","pages":"Article 102876"},"PeriodicalIF":2.7,"publicationDate":"2025-03-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143785661","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Couple-based group intervention for social isolation in colorectal cancer couples: A pilot study","authors":"Can Wang ,&nbsp;Xiaoke Qiu ,&nbsp;Jiayu Mao ,&nbsp;Xueli Yang ,&nbsp;Yi Lin ,&nbsp;Jie Zhao ,&nbsp;Qiuping Li","doi":"10.1016/j.ejon.2025.102878","DOIUrl":"10.1016/j.ejon.2025.102878","url":null,"abstract":"<div><h3>Purpose</h3><div>Colorectal cancer (CRC) patients and their spousal caregivers frequently experience social isolation. Nevertheless, interventions targeting social isolation mitigation in CRC dyads remain limited. This pilot study aimed to evaluate the feasibility, acceptability, and preliminary effects of couple-based group intervention for alleviating social isolation in Chinese CRC couples.</div></div><div><h3>Methods</h3><div>The study utilized a single-arm pre-post intervention design, comprising a structured six-session group program that blended face-to-face and online components. Feasibility was evaluated through recruitment and retention rates. Acceptability was assessed via a mixed-methods approach combining post-intervention surveys with open-ended interviews. Outcome measures included validated instruments: the General Alienation Scale, Lubben Social Network Scale-6, Medical Outcomes Study 12-item Short-Form version 2, Dyadic Coping Inventory, and Perceived Social Support Scale.</div></div><div><h3>Results</h3><div>The program demonstrated feasibility with a 62.5 % recruitment rate and an 85 % retention rate. Quantitative and qualitative data supported its acceptability through CRC couples' overall satisfaction. Effectiveness was evidenced by medium effect sizes (Cohen's d = 0.54–0.59) on both subjective and objective measures of social isolation and most secondary outcomes in CRC patients and spousal caregivers. Notably, spousal caregivers showed borderline significant improvements in physical health (d = 0.50, <em>P</em> = 0.056) and social support (d = 0.49, <em>P</em> = 0.063).</div></div><div><h3>Conclusion</h3><div>The feasibility, acceptability, and preliminary effects of the couple-based group intervention for social isolation in CRC couples were confirmed. These findings warrant a large-scale randomized controlled trial to rigorously evaluate the intervention's long-term effectiveness and potential for clinical implementation.</div></div>","PeriodicalId":51048,"journal":{"name":"European Journal of Oncology Nursing","volume":"76 ","pages":"Article 102878"},"PeriodicalIF":2.7,"publicationDate":"2025-03-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143747286","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}