European Journal of Oncology Nursing最新文献

{"title":"Understanding psychological financial hardship in lung cancer: latent profiles and correlates with patient and caregiver factors.","authors":"Shumin Jia, Pui Hing Chau, Denise Shuk Ting Cheung, Yongchun Cui, Chia-Chin Lin","doi":"10.1016/j.ejon.2025.102999","DOIUrl":"https://doi.org/10.1016/j.ejon.2025.102999","url":null,"abstract":"<p><strong>Purpose: </strong>Lung cancer imposes a significant financial burden, including psychological financial hardship (PFH). This study aims to identify latent profiles of PFH in lung cancer patients and determine associated patient and caregiver factors.</p><p><strong>Methods: </strong>A cross-sectional analysis was conducted with 305 lung cancer patient-caregiver dyads. PFH was measured using the Comprehensive Score for Financial Toxicity (COST), while quality of life (QoL) and distress were also assessed. Latent Profile Analysis (LPA) identified PFH profiles, and one-way ANOVA examined their associations with QoL and distress. Multinomial logistic regression examined correlates of PFH profiles.</p><p><strong>Results: </strong>Three PFH profiles were identified: high-level (COST 0-13), low-level (COST 14-29), and no PFH (COST 30-44). These profiles had medium effects on mental QoL (η² = 0.204), physical QoL (η² = 0.150), and distress (η² = 0.230), indicating clinical significance. Compared with no PFH group, lower caregiver education increased the odds of patients being in high-level PFH groups (OR = 3.847, 95 % CI: 1.038-11.717, p = 0.043); farming occupation was strongly associated with high-level PFH (OR = 9.658, 95 % CI: 3.369-27.689, p < 0.001); in contrast, those not reporting financial sacrifices were substantially less likely to experience high-level PFH (OR = 0.066, 95 % CI: 0.022-0.195, p < 0.001).</p><p><strong>Conclusions: </strong>Distinct PFH profiles and correlates were identified, highlighting the role of both patient and caregiver factors. Findings underscore the importance of early screening and family-centred interventions to mitigate financial hardship and support well-being in cancer care.</p>","PeriodicalId":51048,"journal":{"name":"European Journal of Oncology Nursing","volume":"79 ","pages":"102999"},"PeriodicalIF":2.7,"publicationDate":"2025-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145287659","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Informing the development of a nurse-led survivorship intervention for men with prostate cancer treated with androgen deprivation therapy: A qualitative exploratory study.","authors":"Sally A M Sara, Nicole Heneka, Suzanne K Chambers, Jeff Dunn, Victoria R Terry","doi":"10.1016/j.ejon.2025.103002","DOIUrl":"https://doi.org/10.1016/j.ejon.2025.103002","url":null,"abstract":"<p><strong>Purpose: </strong>To inform the development of a nurse-led survivorship intervention for men with prostate cancer treated with androgen deprivation therapy (ADT).</p><p><strong>Methods: </strong>Qualitative exploratory study using semi-structured interviews with men undergoing ADT and specialist nurses. Recruitment occurred purposively via Prostate Cancer Foundation Australia networks. Interview recordings were transcribed and thematically analysed. Reporting adheres to COREQ guidelines.</p><p><strong>Findings: </strong>Ten men and ten nurses were interviewed. Thematic analysis of interviews identified four key themes related to the importance of tailored information provision; the value of timely, personalised and accessible support from health professionals; men's preparedness for managing the impact of ADT; program preferences for a survivorship program for men on ADT. Men felt inadequately prepared for the side-effects of ADT and called for clearer, tailored information and personalised support extending beyond initiation of treatment. Nurses acknowledged that ADT side-effects are debilitating and challenging to manage and called for a guided education and support program targeted to individual needs with evidence-based resources, tools and checklists.</p><p><strong>Conclusions: </strong>ADT has a debilitating impact on physical and psychological health, and quality of life. Nurse-led survivorship interventions are needed that are flexible and tailorable to individual needs that men themselves express, incorporating nurses' delivery preferences in order to maximise effectiveness. Men prescribed ADT should be provided with a tailored education and support program and connected to a trained Prostate Cancer Specialist Nurse for ongoing, personalised support.</p>","PeriodicalId":51048,"journal":{"name":"European Journal of Oncology Nursing","volume":"79 ","pages":"103002"},"PeriodicalIF":2.7,"publicationDate":"2025-10-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145294386","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effectiveness and determinants of a digital health application-delivered intervention to promote rehabilitation exercises in non-adherent head and neck cancer patients: A clinical trial.","authors":"Tong Wu, Ting Han, Zehui Feng, Mingxuan Wang, Xiaoju Zhang, Dian Zhu, Yumei Dai, Xiaoyan Meng","doi":"10.1016/j.ejon.2025.103000","DOIUrl":"https://doi.org/10.1016/j.ejon.2025.103000","url":null,"abstract":"<p><strong>Purpose: </strong>To evaluate the impact of a digital health application using the Health Belief Model and computer vision on head and neck cancer rehabilitation, and explore strong factors related to rehabilitation within the model.</p><p><strong>Methods: </strong>A randomised controlled trial was conducted involving 108 patients with head and neck cancer (intervention group = 54, control group = 54). The intervention group received rehabilitation guided by the application, while the control group received usual care. Mandibular function, training adherence, health beliefs, pain perception, rehabilitation knowledge, fatigue, and quality of life between groups at T0 (baseline), T1 (1 month) and T2 (3 months) were assessed. Two-way ANOVA and multivariate regression with Bootstrap sampling were used to assess between group differences, intervention-time interactions, and mediation effects.</p><p><strong>Results: </strong>The intervention significantly improved maximal mouth-opening (p < 0.001), mandibular function (p < 0.001), training frequency and duration (p < 0.001), perceived severity (p = 0.039), perceived benefits (p = 0.003), self-efficacy (p = 0.001), action cues (p < 0.001), and rehabilitation knowledge (p < 0.001). Additionally, the intervention group experienced a significant reduction in fatigue (p < 0.001). Mediation analysis showed that self-efficacy had the strongest positive mediating effect. Action cues and perceived benefits demonstrated both immediate (T0<T1, p < 0.001) and sustained (T0<T2, Cohen's d = -0.452) complementary effects. Although perceived severity enhanced rehabilitation knowledge (β = 0.378), it was also associated with increased fatigue (β = 0.389).</p><p><strong>Conclusions: </strong>A Health Belief Model-based digital intervention significantly enhanced rehabilitation outcomes by improving self-efficacy, leveraging the complementary effects of perceived benefits and action cues, as well as the bidirectional effect of perceived severity.</p><p><strong>Registration: </strong>Clinical trial registration:ChiCTR2400090305 (2024/09/27).</p>","PeriodicalId":51048,"journal":{"name":"European Journal of Oncology Nursing","volume":"79 ","pages":"103000"},"PeriodicalIF":2.7,"publicationDate":"2025-10-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145294400","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Assessment and future projection of brain and central nervous system cancer burden using a modified quality care index: evidence from the Global Burden of Disease 2021","authors":"Chen Xu ,&nbsp;Enhui Zhou ,&nbsp;Yin Shen ,&nbsp;Lili Xiao ,&nbsp;Weijun Huang ,&nbsp;Tianjiao Zhou ,&nbsp;Jinxiu Yao ,&nbsp;Wen Lu ,&nbsp;Feifei Xu ,&nbsp;Siqiong Jiang ,&nbsp;Hongliang Yi","doi":"10.1016/j.ejon.2025.102997","DOIUrl":"10.1016/j.ejon.2025.102997","url":null,"abstract":"<div><h3>Purpose</h3><div>This study aimed to assess global central nervous system (CNS) cancer care quality and predict future trends, focusing on age, sex, and socioeconomic determinants.</div></div><div><h3>Methods</h3><div>A cross-sectional study was conducted using data from the Global Burden of Disease (GBD) database (1990–2021). Principal component analysis (PCA) was applied to develop a composite quality of care index (QCI). Stratified analyses were performed by sociodemographic index (SDI), sex, and age groups. Linear mixed-effects models (LMM) were used to evaluate associations, and Bayesian age-period-cohort (BAPC) analysis projected QCI trends from 2022 to 2050.</div></div><div><h3>Results</h3><div>From 1990 to 2021, global CNS cancer QCI improved but showed significant regional heterogeneity. Japan had the highest QCI (100), while China exhibited the fastest annual growth rate (3.41 %). Females consistently had higher QCI (37.49) compared to males (32.98). QCI declined with advancing age (5–9 years: β = −0.309; 95+ years: β = −2.385) and increased with higher SDI levels (low-middle SDI: β = 0.156; high SDI: β = 1.669). High-SDI countries accounted for 53.13 % of age-related QCI improvements. Projections indicated a sustained increase in global QCI from 2022 to 2050.</div></div><div><h3>Conclusions</h3><div>This study introduced a novel QCI framework to evaluate global CNS cancer care quality, projecting continued improvements until 2050. High-SDI regions demonstrated superior healthcare outcomes compared to low-SDI areas, with distinct age-related patterns. The findings highlight the urgent need for targeted healthcare investments in low-SDI regions and global collaborations to reduce disparities and enhance healthcare delivery worldwide.</div></div>","PeriodicalId":51048,"journal":{"name":"European Journal of Oncology Nursing","volume":"79 ","pages":"Article 102997"},"PeriodicalIF":2.7,"publicationDate":"2025-10-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145222824","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of family-centered empowerment program on quality of life and caregiving burden in family caregivers of patients with hematologic malignancies: A quasi-experimental study","authors":"Fatemeh Rashidi ,&nbsp;Mohammad Abbasi ,&nbsp;Hashim Hamid Shabeeb ,&nbsp;Niloofar Ahmadi","doi":"10.1016/j.ejon.2025.102996","DOIUrl":"10.1016/j.ejon.2025.102996","url":null,"abstract":"<div><h3>Purpose</h3><div>Supporting family caregivers plays a crucial role in cancer management. This study aimed to determine the effect of a Family-Centered Empowerment Program (FCEP) on the quality of life and caregiving burden in family caregivers of patients with hematologic malignancies.</div></div><div><h3>Methods</h3><div>This study employed a quasi-experimental pretest-posttest design with a control group, conducted from April to September 2024. The participants were recruited through convenience sampling and then divided into an experimental (n = 33) and a control group (n = 33). The experimental group received a four-step FCEP, while the control group only received standard care. Data collection instruments included the Caregiver Quality of Life Index-Cancer and Novak and Guest's Caregiving Burden Inventory.</div></div><div><h3>Results</h3><div>The results showed that at baseline, there was no significant difference between experimental and control groups in terms of quality of life and care burden, however, one month after the implementation of the FCEP, there was a statistically significant difference in the economic concern dimension (Experimental: 21.96 ± 5.33 vs. Control: 18.0 ± 6.23; <em>P</em> = <em>0.009</em>) and overall quality of life (Experimental: 78.06 ± 14.96 vs. Control: 69.03 ± 15.91; <em>P</em> = <em>0.024</em>) between the experimental and control groups. Additionally, one month after the implementation of FCEP, there was a statistically significant difference in the time-dependent (Experimental: 9.12 ± 2.32 vs. Control: 12.54 ± 4.10; <em>P &lt; 0.001</em>), social (Experimental: 4.18 ± 2.54 vs. Control: 6.22 ± 3.27; <em>P</em> = <em>0.008</em>), and overall caregiving burden (Experimental: 32.06 ± 7.11 vs. Control: 39.96 ± 13.15; <em>P</em> = <em>0.004</em>) between the experimental and control groups.</div></div><div><h3>Conclusion</h3><div>The findings of this study confirmed the effectiveness of the FCEP in improving caregivers' quality of life and reducing their care burden in various dimensions.</div></div>","PeriodicalId":51048,"journal":{"name":"European Journal of Oncology Nursing","volume":"79 ","pages":"Article 102996"},"PeriodicalIF":2.7,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145245839","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Exploring psychological resilience as a mediator between frailty and health-related quality of life among older cancer survivors: a cross-sectional study","authors":"Xueyan Cheng ,&nbsp;Miho Sato ,&nbsp;Xuyang Zhang ,&nbsp;Pui Hing Chau ,&nbsp;Takahiro Osawa ,&nbsp;Yosuke Konno ,&nbsp;Chia-Chin Lin ,&nbsp;Denise Shuk Ting Cheung","doi":"10.1016/j.ejon.2025.102993","DOIUrl":"10.1016/j.ejon.2025.102993","url":null,"abstract":"<div><h3>Purpose</h3><div>To examine the potential mediating role of psychological resilience in the relationship between frailty and Health related quality of life (HRQoL) among older cancer survivors.</div></div><div><h3>Methods</h3><div>This cross-sectional study recruited 314 older cancer survivors in Japan and Hong Kong. Questionnaires on frailty, psychological resilience, and HRQoL were administered. The associations among the variables were analyzed using multivariable linear regressions, and psychological resilience was tested as a mediator between frailty and global HRQoL using mediation analysis.</div></div><div><h3>Results</h3><div>Prefrail (β = -3.93, 95 %CI: −7.72, −0.14, <em>p</em> = 0.042) and frail (β = -11.77, 95 %CI: −19.33, −4.21, <em>p</em> = 0.002) participants showed significantly lower psychological resilience than robust individuals. Frailty was negatively associated with global HRQoL, physical, role, and cognitive functioning (β ranged from −17.22 to −14.00, all <em>p</em> &lt; 0.001), and positively associated with fatigue (β = 21.48, 95 %CI: 11.49, 31.46, p &lt; 0.001) and pain (β = 16.51, 95 %CI: 7.33, 25.69, p &lt; 0.001) compared with robust group. Psychological resilience was positively associated with global HRQoL, emotional, cognitive, and social functioning (β ranged from 0.19 to 0.41, all <em>p</em> &lt; 0.001), and negatively associated with insomnia (β = −0.51, 95 %CI: −0.73, −0.30, <em>p</em> &lt; 0.001). Psychological resilience partially mediated the relationship of frailty and global HRQoL, accounting for 32.3 % and 21.9 % of the total effect in prefrail and frail groups, respectively.</div></div><div><h3>Conclusion</h3><div>Psychological resilience served as a mediator in the association between frailty and HRQoL in older cancer survivors. Programs incorporating frailty-reducing and resilience-enhancing strategies may be helpful to improve HRQoL among older cancer survivors, particularly those who are pre-frail or frail.</div></div>","PeriodicalId":51048,"journal":{"name":"European Journal of Oncology Nursing","volume":"79 ","pages":"Article 102993"},"PeriodicalIF":2.7,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145222825","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Mindfulness-based self-compassion to enhance ontological well-being in breast cancer survivors: A randomized controlled trial","authors":"Behice Belkıs Çalışkan ,&nbsp;Fatma Yasemin Kutlu","doi":"10.1016/j.ejon.2025.102983","DOIUrl":"10.1016/j.ejon.2025.102983","url":null,"abstract":"<div><h3>Purpose</h3><div>This study aimed to evaluate the effectiveness of an 8-week mindfulness-based self-compassion program (MBSCP) in enhancing ontological well-being (OWB) among breast cancer survivors.</div></div><div><h3>Methods</h3><div>A randomized controlled trial was conducted at a university hospital in Türkiye. Seventy-one women with a history of breast cancer were randomized into an intervention group (n = 35) or a control group (n = 36). The intervention group received the MBSCP, while the control group received no additional support. Ontological well-being was measured using the Ontological Well-Being Scale (OWBS) at baseline, post-intervention, and 3-month follow-up. Data were analyzed using repeated measures ANOVA.</div></div><div><h3>Results</h3><div>Participants in the intervention group demonstrated statistically significant improvements in overall OWBS scores and in the subscales of \"hope,\" \"action,\" and \"nothingness\" compared to the control group (p &lt; .001). No significant differences were observed for the \"regret\" subscale.</div></div><div><h3>Conclusions</h3><div>The MBSCP effectively enhanced ontological well-being in breast cancer survivors. These findings suggest that integrating mindfulness-based existential support into survivorship care may promote psychological resilience and holistic well-being.</div></div>","PeriodicalId":51048,"journal":{"name":"European Journal of Oncology Nursing","volume":"79 ","pages":"Article 102983"},"PeriodicalIF":2.7,"publicationDate":"2025-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145253511","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The effect of oral cryotherapy on taste alteration, appetite level, risk of malnutrition and quality of life in patients undergoing chemotherapy: A randomized controlled trial","authors":"Zeynep Pehlivan Köksal ,&nbsp;Nesrin Nural ,&nbsp;Oğuzhan Kesen","doi":"10.1016/j.ejon.2025.102991","DOIUrl":"10.1016/j.ejon.2025.102991","url":null,"abstract":"<div><h3>Purpose</h3><div>This study aimed to evaluate the effect of oral cryotherapy on chemotherapy-induced taste alteration, appetite, nutritional risk, and quality of life in patients undergoing chemotherapy.</div></div><div><h3>Methods</h3><div>A randomized controlled trial was conducted with 65 patients receiving outpatient chemotherapy. Participants were assigned to an intervention group (oral cryotherapy plus standard care) or a control group (standard care only). Data were collected using validated tools, including the Chemotherapy-Induced Taste Alteration Scale (CITAS), the Simplified Nutritional Appetite Questionnaire (SNAQ), the Malnutrition Universal Screening Tool (MUST), and the EORTC QLQ-C30.</div></div><div><h3>Results</h3><div>Compared with the control group, patients receiving oral cryotherapy reported significantly lower levels of taste alteration and discomfort, alongside higher appetite and overall quality of life scores (p &lt; 0.05). Nutritional markers such as albumin and total protein remained stable in the intervention group, while they declined in controls. These results suggest that oral cryotherapy may both alleviate taste-related symptoms and help maintain nutritional status during chemotherapy.</div></div><div><h3>Conclusion</h3><div>Oral cryotherapy was found to be an effective method for reducing the severity of chemotherapy-induced taste alterations and improving appetite and overall quality of life. Adherence to the protocol was high (%94), though the regimen is intensive and may challenge feasibility in routine practice. These findings highlight the potential of oral cryotherapy as a supportive care strategy, warranting confirmation in larger, multi-center studies.</div></div>","PeriodicalId":51048,"journal":{"name":"European Journal of Oncology Nursing","volume":"79 ","pages":"Article 102991"},"PeriodicalIF":2.7,"publicationDate":"2025-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145234068","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Understanding psychological outcomes in cancer: The interplay between hope, dignity, demoralization, and posttraumatic growth","authors":"Ioanna Tsatsou ,&nbsp;Maria Nikoloudi ,&nbsp;Petros Galanis ,&nbsp;Kyriaki Mystakidou","doi":"10.1016/j.ejon.2025.102984","DOIUrl":"10.1016/j.ejon.2025.102984","url":null,"abstract":"<div><h3>Purpose</h3><div>The study investigates the relationship between hope and dignity with demoralization and posttraumatic growth (PTG) in cancer patients.</div></div><div><h3>Methods</h3><div>Α cross sectional study was conducted with convenience sampling. Participants completed the Hearth Hope Index (HHI), Patient Dignity Inventory (PDI), Demoralization Scale-II (DS-II) and Posttraumatic Growth Inventory (PTGI). Univariate and multivariate linear regressions were performed, taking into account demographic and clinical confounders.</div></div><div><h3>Results</h3><div>A total of 112 patients with various types of cancer participated. Mean age of the participants was 66 years and 22.3 % had lung cancer. Hope was found to be negatively correlated to demoralization (r = −0.75, p-value&lt;0.01) and positively correlated to the various factors of PTGI (r = 0.45, p-value&lt;0.01). Then, dignity was positively correlated with demoralization (r = 0.79, p-value&lt;0.01) but negatively correlated with PTGI (r = -0.37, p-value&lt;0.01). Univariate and multivariable linear regression analysis identified a negative relationship between hope and demoralization (adjusted coefficient beta = −0.574, 95 %CI = −0.769 to −0.380, p-value&lt;0.001), a positive association between dignity and demoralization (adjusted coefficient beta = 0.209, 95 %CI = 0.156 to 0.261, p-value&lt;0.001) and negative association between dignity and the factor “new possibilities” of the PTGI (adjusted coefficient beta = −0.070, 95 %CI = −0.116 to −0.024, p-value = 0.003). Finally, hope was associated with increased confrontation (adjusted coefficient beta = 0.258, 95 % CI = 0.047 to 0.469, p-value = 0.017), appreciation of life (adjusted coefficient beta = 0.215, 95 % CI = 0.074 to 0.357, p-value = 0.003), and spiritual change of the PTGI (adjusted coefficient beta = 0.134, 95 %CI = 0.019 to 0.249, p-value = 0.022).</div></div><div><h3>Conclusions</h3><div>Enhancing hope and dignity in cancer patients may contribute significantly to reducing demoralization and enhancing posttraumatic growth. There is a need for holistic interventions that take into account the emotional and existential dimensions of cancer.</div></div>","PeriodicalId":51048,"journal":{"name":"European Journal of Oncology Nursing","volume":"79 ","pages":"Article 102984"},"PeriodicalIF":2.7,"publicationDate":"2025-09-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145187268","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Changes in hope, resilience and social support throughout chemotherapy and their association with health-related quality of life in cancer patients: A longitudinal study","authors":"Sheung Yiu Chan ,&nbsp;Xueyan Cheng ,&nbsp;Pui Hing Chau ,&nbsp;Hui-Mei Chen ,&nbsp;Wing Lok Chan ,&nbsp;Chia-Chin Lin ,&nbsp;Denise Shuk Ting Cheung","doi":"10.1016/j.ejon.2025.102981","DOIUrl":"10.1016/j.ejon.2025.102981","url":null,"abstract":"<div><h3>Objective</h3><div>To investigate the association between changes in hope, resilience, social support, and cancer-related symptoms, and the change in health-related quality of life among cancer patients during chemotherapy.</div></div><div><h3>Methods</h3><div>A prospective, longitudinal study was conducted among 126 cancer patients undergoing chemotherapy. Hope, resilience, and social support were measured using the Herth Hope Index, 14-item Resilience Scale, and Multidimensional Scale of Perceived Social Support, respectively. Quality of life was assessed using Functional Assessment of Cancer Therapy–General. All measures were administered before chemotherapy started and 1 month after chemotherapy completion. Linear mixed models were employed to analyze the changes in hope, resilience, social support, and quality of life. Multivariable linear regression analysis was employed to assess the association between the changes in the psychosocial variables and quality of life.</div></div><div><h3>Results</h3><div>Physical well-being and emotional well-being significantly improved 1 month after chemotherapy compared to baseline, while no significant change was observed in hope, resilience, or social support. Change in resilience was positively associated with emotional well-being (β = 0.09, 95 %CI: 0.003, 0.18), functional well-being (β = 0.16, 95 %CI: 0.09, 0.23), and overall quality of life (β = 0.33, 95 %CI: 0.09, 0.57). Change in social support showed a positive association with change in social well-being (β = 0.16, 95 %CI: 0.06, 0.25).</div></div><div><h3>Conclusions</h3><div>This longitudinal study demonstrates that improvements in resilience and social support are positively associated with enhanced quality of life during chemotherapy. Interventions enhancing resilience and social support may help to support cancer patients better during chemotherapy.</div></div>","PeriodicalId":51048,"journal":{"name":"European Journal of Oncology Nursing","volume":"79 ","pages":"Article 102981"},"PeriodicalIF":2.7,"publicationDate":"2025-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145134831","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}