European Journal of Oncology Nursing最新文献

{"title":"Marital adjustment, depression and quality of life of women with breast cancer and their intimate partners","authors":"Díaz-Heredia Luz Patricia ,&nbsp;Bueno-Robles Luz Stella ,&nbsp;Sansoni Julita ,&nbsp;Bejarano Beltrán Martha Patricia ,&nbsp;Pardo Torres Myriam Patricia ,&nbsp;Rosero Otero Mildred ,&nbsp;Erazo Martínez Myriam","doi":"10.1016/j.ejon.2024.102765","DOIUrl":"10.1016/j.ejon.2024.102765","url":null,"abstract":"<div><h3>Purpose</h3><div>Among all the types of cancer, breast cancer occurs most frequently in women. The diagnosis and treatments for this disease generate physical and emotional discomfort that affects the quality of life of both the woman and her intimate partners. Aim. The aim was to establish the relationship between marital adjustment, depression and quality of life of both women with breast cancer and their intimate partners.</div></div><div><h3>Methods</h3><div>A cross-sectional study with 143 couples composed of women diagnosed with breast cancer and their respective intimate partners, living in Colombia and Italy, were evaluated about Sociodemographic characteristics, marital adjustment, depression, and quality of life. Measures of central tendency, correlational coefficients and both simple and multiple regression analysis were applied.</div></div><div><h3>Results</h3><div>Significant correlations were reported for the variable marital adjustment (t: 0.35; p &lt; 0.001) and depression (t:0.49; p &lt; 0.001) between women and their intimate partners in Colombia, while the variables depression (t: 0.77; p &lt; 0.001) and quality of life (t: 0.50; p &lt; 0.001) showed significant correlations between couples in Italy.</div><div>Regarding the multiple regression model, it was found that the quality of life of the couples was not affected by the behavior observed in the variable depression and marital adjustment. However, when including the variable country of origin (Colombia and Italy), a significant effect on quality of life was observed (t = −2.126; p &lt; 0.034).</div></div><div><h3>Conclusions</h3><div>The quality of life of the woman and her intimate partner was related to the country where they live, a variable that is related to the timeliness and quality of health services. This result invites all professionals who care for this group of women to offer the best possible care by optimizing the resources available.</div></div>","PeriodicalId":51048,"journal":{"name":"European Journal of Oncology Nursing","volume":"74 ","pages":"Article 102765"},"PeriodicalIF":2.7,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142899247","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"To get through to survive: Exploring the symptom cluster management process during oncological treatment from the perspective of patients with lung cancer – A grounded theory study","authors":"Katarina Karlsson ,&nbsp;Maria Larsson ,&nbsp;Karin Ahlberg ,&nbsp;Ann Erlandsson ,&nbsp;Cecilia Olsson","doi":"10.1016/j.ejon.2024.102764","DOIUrl":"10.1016/j.ejon.2024.102764","url":null,"abstract":"<div><h3>Purpose</h3><div>To explore the symptom cluster management process from the perspective of patients with lung cancer within the oncological care context.</div></div><div><h3>Methods</h3><div>We used a constructivist grounded theory methodology to collect and analyze rich data from 15 patients with lung cancer via individual interviews and a two-dimensional symptom assessment scale.</div></div><div><h3>Results</h3><div>A situational theoretical model describes the symptom cluster management process through the main category ‘To get through to survive’, with the category ‘Handling symptom clusters’ together with six sub-categories concerning the patients' management strategies and the category ‘Living with symptom clusters,’ together with two sub-categories describing the outcome in their daily life. Impacting conditions are incorporated in the model.</div></div><div><h3>Conclusions</h3><div>Patients often feel left to their own devices to deal with symptom clusters and may not understand or foresee problematic circumstances as they manage their situations on a day-to-day basis. When symptoms are normalized and accepted, patients do not ask for support, or support is not being offered to them. Healthcare professionals should consider the peril of normalizing symptoms and the patients’ altered time perspective that stems from their approach of living one day at a time, in further development of nursing interventions and person-centered care for this population.</div></div>","PeriodicalId":51048,"journal":{"name":"European Journal of Oncology Nursing","volume":"74 ","pages":"Article 102764"},"PeriodicalIF":2.7,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142899702","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The effects of a psychoeducational intervention on caregivers of colorectal cancer patients: A meta-analysis of randomized controlled trials","authors":"Menghan Zhang ,&nbsp;Yanyan Xue ,&nbsp;Mengwei Shao ,&nbsp;Yi Yang ,&nbsp;Lulu Yu ,&nbsp;Bin Ma ,&nbsp;Dunhui Li ,&nbsp;Huiyue Zhou ,&nbsp;Kun Wang ,&nbsp;Changying Chen ,&nbsp;Mengzhuo Cheng ,&nbsp;Tao Wang","doi":"10.1016/j.ejon.2024.102739","DOIUrl":"10.1016/j.ejon.2024.102739","url":null,"abstract":"<div><h3>Purpose</h3><div>To investigate the impacts of psychoeducational interventions in adjusting the physical and psychological statuses of caregivers of CRC patients.</div></div><div><h3>Methods</h3><div>Nine electronic databases, including Medline, Web of Science, Embase, Cochrane Library, CINAHL Complete, CNKI, Wan Fang Database, VIP Database, and CBM, were searched to identify eligible randomized controlled trials from January 2000 to July 2023. From 1498 articles, 9 articles that met the inclusion criteria were identified and systematically analyzed. Effect sizes and moderator variables were tested using both fixed-effect models and random-effect models.</div></div><div><h3>Results</h3><div>Our results clearly showed that although psychoeducational interventions could improve all aspects of the physical health of caregivers of CRC patients, resulting in improved quality of life, reduced caregiver burden, and enhanced caregiver ability, they only partly affect the psychological conditions of caregivers. For example, while it led to improved positive coping, alleviated negative coping, and decreased disruption in the caring schedule, there were quite a few key aspects of the psychological status that did not show responses, including perception of family support, financial burden, self-esteem, and distress.</div></div><div><h3>Conclusion</h3><div>Psychoeducational interventions can significantly improve the status of caregivers of CRC both physically and psychologically and encourage active lifestyles. However, there are still outstanding problems to be solved in the psychological aspects of caregivers, such as how to improve their social support, and how to relieve their financial pressure. Even so, we firmly believe developing a standardized psychoeducational intervention mode is of great significance in improving the general well-being of caregivers of CRC patients.</div></div><div><h3>Systematic review registration</h3><div>PROSPERO (<span><span>http://www.crd.york.ac.uk/PROSPERO</span><svg><path></path></svg></span>), number CRD42023484775.</div></div>","PeriodicalId":51048,"journal":{"name":"European Journal of Oncology Nursing","volume":"74 ","pages":"Article 102739"},"PeriodicalIF":2.7,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142899731","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"School-based social and educational support for siblings of children with cancer - Siblings' and parents’ feedback on an intervention proposal (SUPREME)","authors":"Minna Devantier ,&nbsp;Marianne Olsen ,&nbsp;Mette Asbjoern Neergaard ,&nbsp;Ayo Wahlberg ,&nbsp;Natasha Nybro Boensvang ,&nbsp;Hanne Bækgaard Larsen","doi":"10.1016/j.ejon.2024.102768","DOIUrl":"10.1016/j.ejon.2024.102768","url":null,"abstract":"<div><h3>Purpose</h3><div>Siblings of children with cancer experience the consequences of their brother or sister's disease and treatment firsthand, often causing social and school-related difficulties. This study aimed to gather parents' and siblings' feedback on a proposal for a school-based social and educational support intervention for siblings with the goal of tailoring the program to meet the needs of siblings.</div></div><div><h3>Method</h3><div>Adopting a criterion sampling strategy, we conducted interviews with 20 parents and 11 siblings, aged 7–19 years, of children with cancer. During the interviews, we introduced a proposal for a school-based intervention as part of a co-creation design. Data were examined by content analysis.</div></div><div><h3>Results</h3><div>The analysis showed that both parents and siblings recognized: 1) the need to inform the class about the family's situation, 2) the need for the timing and content of the support to align with the family's stage in the cancer journey. 3) Parents' concerns centered on potentially imposing experiences on siblings, losing school as a ‘free space’, and the risk of siblings standing out. 4) Siblings' concerns related to a fear of losing control over the cancer-related information at school and the reactions of peers. The final SUPREME intervention involved clarifying family meetings before two educational, nurse-led school visits addressing challenges relevant to siblings' academic and social lives.</div></div><div><h3>Conclusion</h3><div>The participants’ responses to the intervention proposal played a key role in shaping the final intervention, encompassing valuable insights into precautions necessary for implementing school-based support for siblings of children with cancer.</div></div>","PeriodicalId":51048,"journal":{"name":"European Journal of Oncology Nursing","volume":"74 ","pages":"Article 102768"},"PeriodicalIF":2.7,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142873349","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Posttraumatic growth trajectories of couples with gynecological cancer: A longitudinal study","authors":"Yongfeng Tang ,&nbsp;Yuanyuan Song ,&nbsp;Dinghua Yang ,&nbsp;Yuan Qin ,&nbsp;Lei Wang ,&nbsp;Xiaolian Jiang","doi":"10.1016/j.ejon.2025.102795","DOIUrl":"10.1016/j.ejon.2025.102795","url":null,"abstract":"<div><h3>Purpose</h3><div>We aimed to describe and compare posttraumatic growth (PTG) levels among gynecological cancer patients and spouses at various time points within one year of diagnosis, as well as to investigate the association, trajectory, and subgroup characteristics of their PTG.</div></div><div><h3>Methods</h3><div>Couples in a longitudinal observational study filled out questionnaires within 1 month of gynecological cancer diagnosis, as well as 3, 6, and 12 months later. A growth mixture model (GMM) was utilized to explore PTG trajectories. Statistical analyses included Spearman rank correlation, chi-square test, nonparametric test, and post-hoc test.</div></div><div><h3>Results</h3><div>A significant positive correlation was found between the PTG scores of patients and spouses at different times (<em>P</em> &lt; 0.01), with the patients' scores being significantly higher (<em>P</em> &lt; 0.001). Within a year of diagnosis, patients' and their spouses' PTG showed an overall upward trend. The GMM identified three categories for patients' PTG trajectories: high stability (33.7%), decline (19.1%), and low growth (47.2%). Similarly, spouses' PTG trajectories fell into three categories: medium growth (42.8%), decline (8.6%), and low stability (48.6%). Subgroup analysis of patients and spouses with different PTG trajectories indicated significant differences concerning educational attainment, residence location, per capita monthly family income, payment method of patients' medical expenses, and subjective severity of patients' diseases (<em>P</em> &lt; 0.05).</div></div><div><h3>Conclusion</h3><div>This study represents the inaugural effort to investigate the levels and correlations of PTG between gynecological cancer patients and their spouses from a longitudinal perspective. Furthermore, three distinct trajectories were identified for both partners. Patients and spouses exhibiting different PTG trajectories possess unique demographic and disease characteristics.</div></div>","PeriodicalId":51048,"journal":{"name":"European Journal of Oncology Nursing","volume":"74 ","pages":"Article 102795"},"PeriodicalIF":2.7,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143015604","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The mediating effect of psychosomatic symptoms between physical activity and cognitive function among breast cancer patients: A path analysis","authors":"Yu Liu ,&nbsp;Yali Su ,&nbsp;Lixiao Bai ,&nbsp;Ailing Yang ,&nbsp;Shaohua Chen","doi":"10.1016/j.ejon.2024.102761","DOIUrl":"10.1016/j.ejon.2024.102761","url":null,"abstract":"<div><h3>Purpose</h3><div>Psychosomatic symptoms are frequently observed side effects in breast cancer (BC) patients and significantly influence cognitive function. However, limited research has addressed the role of psychosomatic symptoms in the relationship between physical activity and cognitive function. This study aimed to examine the mediating effect of psychosomatic symptoms on the relationship between physical activity and cognitive function in BC patients.</div></div><div><h3>Methods</h3><div>A cross-sectional study was conducted across 10 hospitals in China from April 2022 to February 2023. Cognitive function was assessed using the Functional Assessment of Cancer Therapy-Cognitive Function scale. Exercise frequency, sleep quality, fatigue, anxiety, and depression were measured using the Pittsburgh Sleep Quality Index questionnaire, Cancer Fatigue Scale, Generalized Anxiety Disorder Questionnaire–7, and Patient Health Questionnaire–9, respectively, among 741 BC patients. Correlation analysis and path analysis were performed to explore associations between variables.</div></div><div><h3>Results</h3><div>The prevalence of cognitive impairment in BC patients was found to be 9.58%. The path model demonstrated the best fit when age was included as a moderating variable, and the association between age and sleep disorders was controlled. Physical activity showed a negative correlation with both psychosomatic symptoms and cognitive impairment (<em>p</em> &lt; 0.05). It exerted a direct impact on cognitive impairment (20.3%, <em>p</em> &lt; 0.001) and an indirect impact mediated through anxiety and depression (6.3%, <em>p</em> &lt; 0.001). The total effect in the model was 38.6% (<em>p</em> &lt; 0.001).</div></div><div><h3>Conclusion</h3><div>Physical activity has a pivotal role in improving cognitive function in BC patients, both through direct mechanisms and indirectly by reducing anxiety and depression. While enhancements in sleep quality and fatigue levels were observed, their influence on cognitive function did not reach statistical significance, indicating the need for further research. These findings underscore the importance of incorporating psychological symptom management into supportive care plans to aid cognitive recovery. A combination of physical activity and psychological interventions could provide synergistic benefits, potentially boosting cognitive improvement and enhancing the overall quality of life in BC patients.</div></div>","PeriodicalId":51048,"journal":{"name":"European Journal of Oncology Nursing","volume":"74 ","pages":"Article 102761"},"PeriodicalIF":2.7,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142822653","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Formative evaluation of a mobile chat-based intervention (ChatEx) for promoting exercise behaviour in older cancer survivors","authors":"Denise Shuk Ting Cheung ,&nbsp;Chun Kit Chan ,&nbsp;Ryan E. Rhodes ,&nbsp;Pui Hing Chau ,&nbsp;Chi-Leung Chiang ,&nbsp;Michael Tse ,&nbsp;Man Ping Wang ,&nbsp;Doris Sau Fung Yu ,&nbsp;Chia-Chin Lin","doi":"10.1016/j.ejon.2024.102774","DOIUrl":"10.1016/j.ejon.2024.102774","url":null,"abstract":"<div><h3>Purpose</h3><div>To conduct a formative evaluation of ChatEx to increase and maintain exercise among older cancer survivors.</div></div><div><h3>Methods</h3><div>ChatEx is a blended intervention involving 12 weeks of theory-based instant messages and two in-person training sessions. This pilot study comprises three phases: (1)intervention development: developing a message library reviewed by experts; (2)message library pretesting: exploring the views of older cancer survivors toward the message library and making modifications (<em>n</em> = 20); and (3)intervention pilot testing: piloting the ChatEx using a non-randomized quasi-experimental design using quantitative and qualitative methods among cancer survivors aged 65+ who do not meet current exercise guidelines and have completed treatment (<em>n</em> = 40). Feasibility, Acceptability, aerobic and resistance exercise, exercise capacity, grip strength, frailty, quality of life, exercise self-efficacy were assessed as the main outcomes.</div></div><div><h3>Results</h3><div>ChatEx had a retention rate of 80%, with most participants having moderate/high levels of engagement with messaging, and 100% attendance at in-person sessions. Compared to wait-list control, the intervention group significantly increased the time spent in aerobic exercise at 24 weeks, as well as resistance exercise at both 12 weeks and 24 weeks. The intervention group also had significantly greater improvement in exercise capacity and exercise self-efficacy than control at 24 weeks. Participant interviews revealed five major themes: positive feedback, facilitators of exercise adherence, barriers to exercise adherence, negative feedback, and suggestions for improvement.</div></div><div><h3>Conclusion</h3><div>The findings support the feasibility, acceptability, and potential efficacy of ChatEx in increasing exercise behaviour among older cancer survivors. A full-scale trial with a larger and more diverse sample is now warranted.</div></div>","PeriodicalId":51048,"journal":{"name":"European Journal of Oncology Nursing","volume":"74 ","pages":"Article 102774"},"PeriodicalIF":2.7,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142973152","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"“Are you ready?” A longitudinal interpretative phenomenological analysis of couples’ experiences with breast reconstruction decision-making","authors":"Léa Demeulenaere ,&nbsp;Aurélie Untas ,&nbsp;Cécile Flahault ,&nbsp;Léonor Fasse ,&nbsp;Kristopher Lamore","doi":"10.1016/j.ejon.2025.102781","DOIUrl":"10.1016/j.ejon.2025.102781","url":null,"abstract":"<div><h3>Purpose</h3><div>In this study, we aimed to explore women's and their male partners' experiences with breast reconstruction (BR) decision and to study the evolution of their experiences since undergoing mastectomy to one year after.</div></div><div><h3>Methods</h3><div>Unstructured individual interviews with four couples facing mastectomy for breast cancer and BR decision-making were conducted following mastectomy (T1) and one year after mastectomy (T2). Longitudinal interpretative phenomenological analysis (LIPA) was conducted on the data.</div></div><div><h3>Results</h3><div>A total of 16 interviews were conducted, revealing seven group experiential themes: six applicable across time and one related to a specific timepoint. The results highlight two critical aspects: the ambivalence surrounding BR and the perceived importance of moving forward. Women and their partners expressed mixed feelings about BR, weighing the potential for improved quality of life and body image against fears of surgery and medical complications. The decision to undergo BR evolved over time, influenced by experiences related to body acceptance, aesthetic considerations, practical concerns, and societal norms for femininity. Partners played a significant role in the decision-making process, offering emotional support and influencing the decision both directly and indirectly. Moreover, the interpretative accounts underline how couples may see BR as a strategy for repairing both physical and psychological damage.</div></div><div><h3>Conclusion</h3><div>Our findings emphasize the importance of understanding BR not only as a medical procedure but also as a deeply psychosocial process shaped by individual and relational factors. Furthermore, we provide reflections on the use of LIPA since it is a rarely used method.</div></div>","PeriodicalId":51048,"journal":{"name":"European Journal of Oncology Nursing","volume":"74 ","pages":"Article 102781"},"PeriodicalIF":2.7,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143015286","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"“Try to keep things going” – Use of various resources to balance between caregiving and other aspects of life: An interview study with informal caregivers of persons living with brain tumors in Sweden","authors":"Marie Dahlberg ,&nbsp;Carolina Wannheden ,&nbsp;Stefan Andersson ,&nbsp;Ami Bylund","doi":"10.1016/j.ejon.2025.102779","DOIUrl":"10.1016/j.ejon.2025.102779","url":null,"abstract":"<div><h3>Purpose</h3><div>Persons living with brain tumors may experience severe impairment, requiring social support (i.e., informal care). Although informal caregiving can be rewarding, it can also lead to physical or psychological burdens. The aim of this study was to explore how informal caregivers of persons living with brain tumors use resources available to them, including social support, to balance caregiving with other aspects of life.</div></div><div><h3>Methods</h3><div>Sixteen informal caregivers (14 partners, two adult children) of persons living with brain tumors, varied in gender (10 female, six male), age (26–79 years), and caregiving experience (1–20 years) were interviewed. Data were analyzed using conventional content analysis.</div></div><div><h3>Findings</h3><div>We generated nine categories representing informal caregivers’ strategies grouped by resources used. Intrapersonal resources were used for: <em>Flexibly adjusting to changing life situations</em>; <em>Separating the care recipient from the illness</em>; and <em>Reflectively renegotiating self-expectations</em>. Interpersonal resources were used for: <em>Coping together with the care recipient</em>; <em>Sharing responsibilities within the family</em>; <em>Seeking guidance from persons in similar situations</em>; and <em>Grouping social relations by function</em>. Healthcare and community resources were used for: <em>Active collaborations with healthcare staff</em> and <em>Accessing professional and community resources for mental well-being</em>.</div></div><div><h3>Conclusions</h3><div>Informal caregivers used their intrapersonal, interpersonal, and healthcare and community resources in various ways for mainly emotional and instrumental support. More informational support from healthcare was desired, indicating that healthcare services, along with patient and caregiver organizations, may be able to enhance such support for informal caregivers. This could, in turn, allow more flexibility to manage caregiving alongside other life commitments.</div></div>","PeriodicalId":51048,"journal":{"name":"European Journal of Oncology Nursing","volume":"74 ","pages":"Article 102779"},"PeriodicalIF":2.7,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143015446","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Patient clusters based on demographics, clinical characteristics and cancer-related symptoms: A cross-sectional pilot study","authors":"Greta Ghizzardi ,&nbsp;Stefano Maiandi ,&nbsp;Donatella Vasaturo ,&nbsp;Carmelo Collemi ,&nbsp;Alessandra Laurano ,&nbsp;Arianna Magon ,&nbsp;Silvia Belloni ,&nbsp;Debora Sidoli ,&nbsp;Cristina Cascone ,&nbsp;Lorena Stefania Bassani ,&nbsp;Savizza Calvanese ,&nbsp;Rosario Caruso","doi":"10.1016/j.ejon.2025.102796","DOIUrl":"10.1016/j.ejon.2025.102796","url":null,"abstract":"<div><h3>Purpose</h3><div>This study aimed to identify and preliminary validate distinct clusters of patients with cancer based on demographics, clinical characteristics, and symptoms and to inform future research on sample size requirements for achieving sufficient power in clustering analyses.</div></div><div><h3>Methods</h3><div>This cross-sectional pilot study involved 114 patients with cancer from two hospitals in northern Italy. Data were collected on demographics, clinical characteristics, and 20 symptoms using the Edmonton Symptom Assessment System in October 2022. t-distributed stochastic neighbor embedding (t-SNE) was used to reduce the symptom data and demographics (e.g., age) into two components, which were then clustered using Ward's method. A Monte Carlo simulation was conducted based on the t-SNE components to estimate the sample size needed to achieve 80% power for different cluster solutions (k = 2, 3, 4).</div></div><div><h3>Results</h3><div>Two distinct clusters were identified: Cluster 1 (Higher Symptom Burden Cluster) and Cluster 2 (Lower Symptom Burden Cluster). Cluster 1 patients had a higher prevalence of depression, anxiety, and drowsiness. Monte Carlo simulations indicated that 50 patients per cluster were sufficient for k = 2 clusters to achieve 80% power, whereas 90 patients per cluster were needed for k = 3 clusters and 120 patients per cluster for k = 4 clusters.</div></div><div><h3>Conclusion</h3><div>This study identified distinct patient clusters and provided preliminary evidence on the sample size required for clustering analyses in cancer research. Understanding patient clusters enables nurses to provide tailored interventions, potentially improving symptom management and overall patient care.</div></div>","PeriodicalId":51048,"journal":{"name":"European Journal of Oncology Nursing","volume":"74 ","pages":"Article 102796"},"PeriodicalIF":2.7,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143069394","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}