European Journal of Oncology Nursing最新文献

{"title":"Mediating roles of cancer stigma and resilience in the relationship between type D personality and quality of life among patients with breast cancer undergoing chemotherapy","authors":"Sujin Kim ,&nbsp;Sunki Kim ,&nbsp;Hye-Ja Park","doi":"10.1016/j.ejon.2026.103122","DOIUrl":"10.1016/j.ejon.2026.103122","url":null,"abstract":"<div><h3>Purpose</h3><div>To determine the statistically mediating roles of cancer stigma and resilience in the relationship between Type D personality and quality of life (QoL) in patients with breast cancer undergoing chemotherapy.</div></div><div><h3>Methods</h3><div>This cross-sectional correlational study included 129 inpatients with breast cancer recruited from a university hospital-affiliated cancer center ward. Participants completed questionnaires assessing their Type D personality, cancer stigma, resilience, and QoL. Data were analyzed using Pearson's correlation, hierarchical regression, and PROCESS Macro-mediation analysis (Model 4, 50,000 bootstrap samples).</div></div><div><h3>Results</h3><div>Type D personality negatively correlated with resilience (r = −0.493, <em>p</em> &lt; 0.001) and QoL (r = −0.407, <em>p</em> &lt; 0.001) and positively correlated with cancer stigma (r = 0.387, <em>p</em> &lt; 0.001). Cancer stigma negatively correlated with resilience (r = −0.257, <em>p</em> = 0.003) and QoL (r = −0.455, <em>p</em> &lt; 0.001). Meanwhile, resilience was positively associated with QoL (r = 0.514, <em>p</em> &lt; 0.001). Regression analysis showed that cancer stigma and resilience significantly predicted QoL (β = −0.305, <em>p</em> &lt; 0.001; β = 0.326, <em>p</em> &lt; 0.001), accounting for 26.4% of the variance. Bootstrapped mediation analysis indicated that cancer stigma and resilience explained the link between type D personality and QoL (B = −0.0128, 95% BootCI [−0.0194, −0.0070]). Two significant indirect pathways between type D personality and QoL were identified: perceived cancer stigma (B = −0.0058, 95% BootCI [−0.0104, −0.0018]) and resilience (B = −0.0070, 95% BootCI [−0.0130, −0.0025]).</div></div><div><h3>Conclusion</h3><div>Reducing cancer stigma and enhancing resilience may help improve QoL among patients with breast cancer receiving chemotherapy, particularly those with Type D personality. These findings underscore the importance of targeted psychosocial nursing interventions.</div></div>","PeriodicalId":51048,"journal":{"name":"European Journal of Oncology Nursing","volume":"81 ","pages":"Article 103122"},"PeriodicalIF":2.7,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146116772","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"“You've got to exercise more … What does that mean?” understanding experiences of physical activity during chemotherapy (EPAC): A mixed methods study informed by the COM-B model","authors":"Rebecca Cesnik ,&nbsp;Alanah Pike ,&nbsp;Kellie Toohey ,&nbsp;Nicole Freene ,&nbsp;Stuart Semple","doi":"10.1016/j.ejon.2025.103067","DOIUrl":"10.1016/j.ejon.2025.103067","url":null,"abstract":"<div><h3>Purpose</h3><div>While the benefits of physical activity (PA) during cancer are well known, people undergoing chemotherapy are insufficiently active. This study aims to understand the experiences of PA throughout chemotherapy (EPAC).</div></div><div><h3>Methods</h3><div>The EPAC study used a mixed methods design informed by the capability, opportunity, motivation-behaviour (COM-B) model. Participants currently undergoing outpatient chemotherapy for the treatment of cancer, their carers or cancer care clinicians participated in a semi-structured interview or focus group and a questionnaire. The Godin-Shepard Leisure-Time Questionnaire identified current and pre-chemotherapy PA levels. Qualitative data were analysed using reflexive thematic analysis, and deductively mapped to the COM-B. Descriptive analysis was used for quantitative data.</div></div><div><h3>Results</h3><div>Despite 91 % of people undergoing chemotherapy expressing a desire to be more active, only 17 % were classified as 'active'. Additionally, 78 % of participants reported a decrease in PA during chemotherapy. Ten focus groups and 37 interviews were completed with 40 clinicians, 23 patients, and ten carers. From these, eight themes were developed: PA is part of life; All too much; Physical capacity; Inconsistent education; A desire for PA to be integrated; Tailored access to services; Organisational design and resources; and Workforce sustainability. Subthemes mapped to all components of the COM-B framework.</div></div><div><h3>Conclusion</h3><div>Overall, people undergoing chemotherapy wanted to be more active. Experiences across the groups emphasise the need for increased support to improve opportunities, capability and motivation for PA. These findings demonstrate the need for changes to clinical practice to embed PA into routine chemotherapy care through models that reflect the realities of treatment and its side effects, the workforce, and service design.</div></div>","PeriodicalId":51048,"journal":{"name":"European Journal of Oncology Nursing","volume":"80 ","pages":"Article 103067"},"PeriodicalIF":2.7,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145670840","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cultural acceptability and potential effectiveness of dignity therapy for patients with terminal cancer in Taiwan: A Quasi-Experimental study","authors":"Tzu-Yun Chiu ,&nbsp;Wei-Shu Lai ,&nbsp;Sheng-Yu Fan ,&nbsp;Su-Ying Fang ,&nbsp;Yu-Hsuan Liu","doi":"10.1016/j.ejon.2026.103113","DOIUrl":"10.1016/j.ejon.2026.103113","url":null,"abstract":"<div><h3>Purpose</h3><div>This study assessed the cultural acceptability and clinical effectiveness of dignity therapy (DT) among terminal cancer patients in Taiwan, addressing a significant gap in evidence regarding its applicability in East Asian contexts.</div></div><div><h3>Methods</h3><div>A quasiexperimental, nonrandomized controlled design with integrated qualitative feedback analysis was employed. Twenty-four terminal cancer patients were assigned to either an intervention group (DT plus comfort care, n = 12) or a control group (comfort care only, n = 12). Dignity-related distress was measured using the Patient Dignity Inventory–Mandarin Version (PDI-MV) at baseline, postintervention, and at the two-week follow-up. Acceptability was assessed using the Dignity Therapy Patient and Family Feedback Questionnaires (DTPFQ/DTFFQ). Quantitative data were analyzed using t tests and repeated-measures ANOVA, while qualitative responses were analyzed thematically.</div></div><div><h3>Results</h3><div>Participants in the intervention group experienced a significant reduction in dignity-related distress over time (F = 10.08, <em>P</em> &lt; 0.001), whereas no significant change was observed in the control group (F = 0.70, <em>P</em> = 0.50). High acceptability was reported by participants who received DT (M = 4.21/5) and their family members (M = 4.28/5). Qualitative analysis revealed three overarching themes: (1) emotional catharsis and relief, (2) meaning-making and restoration, and (3) mutual understanding and reconciliation.</div></div><div><h3>Conclusion</h3><div>This study provides preliminary evidence supporting the feasibility, cultural relevance, and potential efficacy of DT in Taiwan. Integrating DT into culturally responsive palliative care may preserve patient dignity, reduce existential distress, and enhance meaningful family communication at the end of life in East Asian contexts.</div></div>","PeriodicalId":51048,"journal":{"name":"European Journal of Oncology Nursing","volume":"80 ","pages":"Article 103113"},"PeriodicalIF":2.7,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146077025","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Lessons learned through childhood cancer: An AI- enhanced PhotoArt-based qualitative study of parental growth and meaning-making","authors":"Ebru Kılıçarslan ,&nbsp;Ebru Akgün Çıtak ,&nbsp;Sibel Dağlıyar ,&nbsp;Sonay İncesoy Özdemi̇r","doi":"10.1016/j.ejon.2026.103098","DOIUrl":"10.1016/j.ejon.2026.103098","url":null,"abstract":"<div><h3>Purpose</h3><div>This qualitative phenomenological study explores how parents of children diagnosed with cancer construct meaning from their caregiving experiences, the lessons they derive, and how these experiences contribute to their growth. Using a descriptive phenomenological design, the study employed AI-generated PhotoArt to elicit and enrich parents’ narratives, facilitating metaphorical expression and deepening narrative insight. By shifting the focus from distress to meaning, the study highlights caregiving as a site of personal growth, value reorientation, and life learning.\"</div></div><div><h3>Method</h3><div>Sixteen parents from a pediatric oncology unit participated in two in-depth individual interviews. In the first, they described an image that symbolized their learning; the second focused on emotional and cognitive transformation. Data were analyzed using Braun and Clarke's six-phase thematic analysis. Personalized AI-generated visuals were created to represent each parent's core theme.</div></div><div><h3>Results</h3><div>Three main themes emerged: (1) Initial experiences of Crisis, marked by emotional collapse, family disruption, and spiritual coping; (2) Lessons Acquired Through the Illness Journey, including resilience, life reprioritization, and empathy through connection; and (3) Constrained Learning Over Time, involving emotional suppression, avoidance, social withdrawal, and mistrust. Visual metaphors like a “broken-winged angel” enriched the emotional depth of verbal narratives.</div></div><div><h3>Conclusion</h3><div>The integration of visual and narrative techniques shows promise in supporting caregiver insight and resilience. Creative, meaning-centered approaches may enhance psycho-oncological support by validating both suffering and growth in the caregiving experience.</div></div>","PeriodicalId":51048,"journal":{"name":"European Journal of Oncology Nursing","volume":"80 ","pages":"Article 103098"},"PeriodicalIF":2.7,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145975906","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Towards integrated palliative care for cancer patients: A qualitative study of case management using the Chronic Care Model","authors":"Shima Yadegar Tirandaz ,&nbsp;Leila Valizadeh ,&nbsp;Vahid Zamanzadeh ,&nbsp;Maryam Rassouli ,&nbsp;Mohammad Esmaeil Akbari","doi":"10.1016/j.ejon.2025.103063","DOIUrl":"10.1016/j.ejon.2025.103063","url":null,"abstract":"<div><h3>Purpose</h3><div>Although palliative care plays a vital role in improving the quality of life for cancer patients and their caregivers, its delivery often involves considerable complexity. Case management has been recommended as a systematic and collaborative approach. Understanding experiences and perceptions of case management in palliative cancer care can provide valuable insights for the development of coordinated, continuous, and patient-centered interventions.</div></div><div><h3>Methods</h3><div>A qualitative study was conducted based on the Chronic Care Model framework. Data were collected through semi-structured, in-depth interviews with 40 participants, including patients, family caregivers, care providers, and policymakers in the field of cancer care. They were analyzed using the directed content analysis approach described by Hsieh and Shannon (2005) and coded using MAXQDA 10 software.</div></div><div><h3>Results</h3><div>Analysis of the interviews guided by the Chronic Care Model components yielded six main categories comprising 16 subcategories: community policies and resources; self-management support; decision support; delivery system design; clinical information systems; and healthcare organizations.</div></div><div><h3>Conclusions</h3><div>The findings indicate that all Chronic Care Model components are essential for a ‘palliative care case management’ framework. This study provides a conceptual extension of the Chronic Care Model and can be used as a sound reference for the development of cancer-related policies and interventions in the healthcare system.</div></div>","PeriodicalId":51048,"journal":{"name":"European Journal of Oncology Nursing","volume":"80 ","pages":"Article 103063"},"PeriodicalIF":2.7,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145624586","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Distress, problems and unmet rehabilitation needs after haematopoietic stem cell transplantation for haematologic malignancies: A cross-sectional study","authors":"Mette Seland ,&nbsp;Sylvia Rognli ,&nbsp;Tone Skaali ,&nbsp;Rune Blomhoff ,&nbsp;Geir E. Tjønnfjord ,&nbsp;Astrid M.A. Eriksen ,&nbsp;Grethe Solvang ,&nbsp;Lene Thorsen","doi":"10.1016/j.ejon.2025.103083","DOIUrl":"10.1016/j.ejon.2025.103083","url":null,"abstract":"<div><h3>Purpose</h3><div>Haematopoietic stem cell transplantation (HSCT) is an intensive treatment potentially resulting in distress, physical and psychosocial problems, and need for rehabilitation services. The purpose of this study was to assess the prevalence of distress, problems, and unmet rehabilitation needs among patients with haematological malignancies treated with HSCT, and to identify demographic and clinical factors associated with being distressed.</div></div><div><h3>Methods</h3><div>A cross-sectional questionnaire-based study among patients with a haematological malignancy was conducted 3-24 months post HSCT. Distress and problems were assessed by the National Comprehensive Network (NCCN) Distress Thermometer (DT) and Problem List (PL), and problems with physical endurance and muscle strength by 11-point scales. Unmet rehabilitation needs were assessed by a questionnaire constructed by the authors.</div></div><div><h3>Results</h3><div>Among 130 invited patients, 98 (75%) were included. Mean observation time since HSCT was 8 months, mean age at survey was 54 years and 61% were male. About half (51%) of the participants reported distress. The most common problems reported on the PL were fatigue (56%), tingling in hands/feet (49%), and worry (47%). Impaired physical endurance and muscle strength were reported by 65% and 59 %, respectively. Thirty-seven percent reported unmet rehabilitation needs. Distressed participants reported more problems included in the PL [mean 10.3 (SD 5.1) vs 4.8 (SD 2.9), p&lt;0.001] and more unmet rehabilitation needs (52% vs 21%, p=0.003) compared to non-distressed participants.</div></div><div><h3>Conclusion</h3><div>The high prevalence of distress, problems and unmet rehabilitation needs emphasize the importance of regular screening and tailored rehabilitation programs in this population.</div></div>","PeriodicalId":51048,"journal":{"name":"European Journal of Oncology Nursing","volume":"80 ","pages":"Article 103083"},"PeriodicalIF":2.7,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146037550","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The role of mindful self-care in enhancing professional quality of life among hospice medical staff in Poland","authors":"Zuzanna Gurzyńska,&nbsp;Aniela Brzezińska,&nbsp;Maciej Walkiewicz","doi":"10.1016/j.ejon.2025.103094","DOIUrl":"10.1016/j.ejon.2025.103094","url":null,"abstract":"<div><h3>Purpose</h3><div>Given the emotionally demanding nature of hospice care, identifying protective factors is essential for promoting caregiver well-being. This study examines compassion fatigue and compassion satisfaction among Polish hospice medical workers, focusing on mindful self-care practices and perceived work support. It also explores whether professional quality of life differs between those who engage in after-work rituals and those who do not.</div></div><div><h3>Methods</h3><div>In a cross-sectional study, 97 hospice medical workers (nurses, physicians, physiotherapists, psychologists, and medical caregivers) completed the Professional Quality of Life Scale (ProQOL), the Mindful Self-Care Scale (MSCS), and an author-developed survey assessing perceived work support and after-work rituals. Participants were recruited from four hospice centres in northern Poland between July 1 and October 31, 2024.</div></div><div><h3>Results</h3><div>Participants reported high levels of MSCS (M = 106.55, SD = 19.60), elevated compassion satisfaction (M = 39.86, SD = 5.94), and normative levels of burnout (M = 21.46, SD = 5.02) and secondary traumatic stress (M = 24.96, SD = 6.20). Mindful self-care was positively associated with compassion satisfaction (r = 0.32, p &lt; 0.001) and negatively associated with burnout (r = −0.49, p &lt; 0.001) and secondary traumatic stress (r = −0.22, p &lt; 0.05). Higher perceived work support correlated with more favorable ProQOL outcomes, as did engaging in after-work rituals.</div></div><div><h3>Conclusions</h3><div>Mindful self-care methods, alongside work support, should be considered potential protective factors against compassion fatigue among hospice staff. It highlights the opportunity for employers to foster supportive work environments and encourage self-care practices tailored to staff needs.</div></div>","PeriodicalId":51048,"journal":{"name":"European Journal of Oncology Nursing","volume":"80 ","pages":"Article 103094"},"PeriodicalIF":2.7,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145938815","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Hematology nurses’ perceptions of implementing primary palliative care for patients with multiple myeloma: A qualitative study","authors":"Shulamit Ohana ,&nbsp;Adir Shaulov ,&nbsp;Freda DeKeyser Ganz","doi":"10.1016/j.ejon.2025.103050","DOIUrl":"10.1016/j.ejon.2025.103050","url":null,"abstract":"<div><h3>Purpose</h3><div>Current palliative care (PC) often relies on specialist consultation. This study focuses on a newer model: integrative PC (primary PC), delivered by regular staff (specifically hematology nurses) who are trained to deliver basic palliative interventions alongside routine clinical care. While established in solid tumors, PC integration lags in hematology. The aim is to describe the hematology nurses' perceptions and experiences providing this integrative PC model to patients with Multiple Myeloma (MM).</div></div><div><h3>Methods</h3><div>A qualitative exploratory study was conducted using a phenomenological-hermeneutic approach. Ten hematology nurses who participated in the implementation were purposively selected and interviewed individually through semi-structured, in-depth interviews conducted by a female nurse researcher experienced in qualitative methods six months after the implementation of an integrative palliative care model. Thematic analysis was applied to identify key patterns and meanings in the data.</div></div><div><h3>Results</h3><div>Three main themes emerged: (1) Becoming a Therapeutic Anchor, (2) Transforming the Role from Clinical Technician to Holistic Caregiver, and (3) Bridging Systemic Gaps as the Care Coordinator. Nurses described enhanced relationships with patients, earlier symptom detection, culturally responsive holistic care, and greater involvement in emotional support and care coordination. They also highlighted the emotional burden of sustaining such care and emphasized the need for institutional support.</div></div><div><h3>Conclusion</h3><div>The findings suggest that hematology nurses may play a significant role in implementing integrative PC for patients with MM. Their involvement enhances holistic care and symptom management. However, sustaining this model requires attention to the emotional demands on nurses and the need for institutional support.</div></div>","PeriodicalId":51048,"journal":{"name":"European Journal of Oncology Nursing","volume":"80 ","pages":"Article 103050"},"PeriodicalIF":2.7,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145670812","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"“It is like he abandoned me in a war” – A qualitative study of relationship distress in parents of children diagnosed with cancer","authors":"Astrid Kuylenstierna ,&nbsp;Pia Enebrink ,&nbsp;Ulrika Kreicbergs ,&nbsp;Gustaf Ljungman ,&nbsp;Malin Lövgren ,&nbsp;Renita Sörensdotter ,&nbsp;Anna Wikman ,&nbsp;Lisa Ljungman","doi":"10.1016/j.ejon.2025.103064","DOIUrl":"10.1016/j.ejon.2025.103064","url":null,"abstract":"<div><h3>Purpose</h3><div>Up to 40 % of parents of children with cancer experience relationship distress; a significantly higher proportion compared to the general population. Despite this elevated risk, there are few in-depth qualitative studies investigating relationship distress in the paediatric oncology context. Therefore, this study aimed to explore how parents of children with cancer experience relationship distress to thereby generate an in-depth understanding of the phenomenon.</div></div><div><h3>Method</h3><div>A sample of 25 parents (17 mothers, 8 fathers) who had experienced relationship distress related to their child's cancer participated in semi-structured interviews exploring relationship dynamics, communication, conflict management, and relational changes following the child's diagnosis. The interviews were audio-recorded, transcribed verbatim, and analysed using inductive content analysis.</div></div><div><h3>Results</h3><div>Three categories and nine subcategories were identified. In addition to these, one overarching theme emerged. The first category ‘Pressure on the relationship’, illustrated factors that placed strain on the couple relationship. The second category ‘When unity fails’ included parents' experiences of challenges in dealing with the situation together as a couple. The third category ‘Fractured togetherness’ highlighted relationship deterioration as a result of the cancer experience. The theme ‘Fighting together, yet drifting apart’ linked the categories by illustrating the process of experiencing joint hardships, of trying to manage these together, but ending up with a wounded relationship.</div></div><div><h3>Conclusion</h3><div>This study contributes with an in-depth understanding of relationship distress in parents of children with cancer. Thereby, it can contribute to the development of currently limited interventions to support parents’ couple relationships in paediatric oncology care.</div></div>","PeriodicalId":51048,"journal":{"name":"European Journal of Oncology Nursing","volume":"80 ","pages":"Article 103064"},"PeriodicalIF":2.7,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145670830","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Preoperative intrinsic capacity phenotypes forecast adverse physical resilience trajectories following surgery in older bladder cancer patients","authors":"Siyu Liu ,&nbsp;Jin Zheng ,&nbsp;Jingyi Sun","doi":"10.1016/j.ejon.2025.103068","DOIUrl":"10.1016/j.ejon.2025.103068","url":null,"abstract":"<div><h3>Purpose</h3><div>This study assessed the predictive value of preoperative intrinsic capacity (IC) phenotypes for physical resilience (PR) trajectories in older adults undergoing elective bladder cancer surgery.</div></div><div><h3>Methods</h3><div>A prospective study was conducted from October 2024 to March 2025 on 327 elderly patients (mean age 69.71 ± 6.96 years) who underwent elective bladder cancer surgery. Latent class analysis (LCA) was used to identify different intrinsic capacity types based on the five domains: vitality, locomotion, cognition, psychology, and sensory. Latent class growth model (LCGM) was applied to identify different trajectories of physical resilience over time. Multiple correspondence analysis (MCA) and multivariate logistic regression were used to study the association between intrinsic capacity types and physical resilience trajectories.</div></div><div><h3>Results</h3><div>LCA identified three intrinsic capacity phenotypes: High intrinsic capacity (35.2 %), Moderate intrinsic capacity-Low Vitality (28.4 %), and Low intrinsic capacity-Low Mobility and Cognition (36.4 %). LCGM identified four physical resilience trajectories: Moderate-Stable (30.6 %), Moderate-Increasing (31.2 %), High-Increasing (28.1 %), and Low-Stable (10.0 %). A significant association was found between intrinsic capacity phenotypes and physical resilience trajectories. After adjustment, the Low Mobility-Cognition and Low Vitality phenotypes were associated with significantly higher risks of adverse recovery trajectories. Poorer self-rated health, lower BMI, and lower education level also predicted worse resilience.</div></div><div><h3>Conclusions</h3><div>Preoperative intrinsic capacity phenotypes, particularly those characterized by deficits in mobility, cognition, and vitality, independently predict physical resilience trajectories in older adults after bladder cancer surgery. Assessing these phenotypes enables early identification of high-risk patients and supports targeted prehabilitation strategies.</div></div>","PeriodicalId":51048,"journal":{"name":"European Journal of Oncology Nursing","volume":"80 ","pages":"Article 103068"},"PeriodicalIF":2.7,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145656388","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}