European Journal of Oncology Nursing最新文献

{"title":"Association between psychological flexibility and self-perceived burden in patients with cervical cancer: A computer-simulated network analysis","authors":"Furong Chen ,&nbsp;Ying Xiong ,&nbsp;Siyu Li ,&nbsp;Yiguo Deng ,&nbsp;Qihan Zhang ,&nbsp;Zhirui Xiao ,&nbsp;M. Tish Knobf ,&nbsp;Zengjie Ye","doi":"10.1016/j.ejon.2025.102822","DOIUrl":"10.1016/j.ejon.2025.102822","url":null,"abstract":"<div><h3>Purpose</h3><div>The study aimed to identify the profiles of psychological flexibility in patients with cervical cancer and how self-perceived burden networked to different psychological flexibility profiles.</div></div><div><h3>Methods</h3><div>The Personalized Psychological Flexibility Index and the Self-Perceived Burden for Cancer Patients were used to measure psychological flexibility and self-perceived burden in patients from the “Be Resilient to Cancer” project. Latent profile analysis was used to identify profiles and computer-simulated network analysis was conducted to determine if self-perceived burden networked to any of the psychological flexibility profiles.</div></div><div><h3>Results</h3><div>A total of 325 patients with cervical cancer were recruited in this study. Mean age was 42.26 years, the majority were married (71%) and 75.4% had early stage disease (I or II). Three profiles of psychological flexibility were identified: moderate avoidance-low acceptance/harnessing (34.8%), high avoidance-moderate acceptance/harnessing (36.9%), low avoidance and high acceptance/harnessing (28.3%). Furthermore, “worrying about damaging family relationships” and “feeling guilty about affecting family's life plans” were the most bridge symptoms as well as the targeted intervention symptoms for alleviating and aggravating the self-perceived burden respectively.</div></div><div><h3>Conclusion</h3><div>Three patterns of psychological flexibility were recognized with two symptoms might be targeted to improve the self-perceived burden in women with cervical cancer.</div></div>","PeriodicalId":51048,"journal":{"name":"European Journal of Oncology Nursing","volume":"74 ","pages":"Article 102822"},"PeriodicalIF":2.7,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143081369","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparative impact of exercise variants on depressive symptoms in cancer patients: A systematic review and network meta-analysis","authors":"Hao Zhang ,&nbsp;Zeyong Hu ,&nbsp;Jiao Tong ,&nbsp;Jianhong Hu ,&nbsp;Xinchao Wang ,&nbsp;Bingnan Wang","doi":"10.1016/j.ejon.2024.102773","DOIUrl":"10.1016/j.ejon.2024.102773","url":null,"abstract":"<div><h3>Purpose</h3><div>The aim of this study was to conduct a network meta-analysis to assess the effectiveness of various forms of exercise as an intervention for post-cancer depression and to provide a guiding program based on evidence-based medicine for subsequent clinical practice.</div></div><div><h3>Methods</h3><div>This review was registered on the PROSPERO website with ID CRD42023485407. Pubmed, Embase, Cochrane Library, and Web of Science were comprehensively searched to obtain published articles from the establishment of the database until October 7, 2023. Bayesian network meta-analysis was conducted. Statistical analysis was conducted using R4.3.2 and Stata 15.1.</div></div><div><h3>Results</h3><div>This study ultimately included 51 articles and 4956 samples. Aerobic exercise (SMD = −0.33, 95%CI: 0.58, −0.08), combined exercise (SMD = −0.48, 95%CI: 0.71, −0.26), and mind-body exercise (SMD = −0.35, 95%CI: 0.6, −0.09) significantly improved depression compared with usual care (UC). According to the SUCRA value and cumulative probability, the rank of depression improvement effect of various sports interventions is as follows: combined exercise (90.71%), mind-body exercise (69.64%), aerobic exercise (65.81%), resistance training (35.86%).</div></div><div><h3>Conclusion</h3><div>Exercise intervention can significantly improve post-cancer depression, but there is no significant difference in the effectiveness of various forms of exercise in improving post-cancer depression.</div></div>","PeriodicalId":51048,"journal":{"name":"European Journal of Oncology Nursing","volume":"74 ","pages":"Article 102773"},"PeriodicalIF":2.7,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142967276","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A cross-sectional analysis to characterise treatment decision making for advanced cancer at a tertiary treatment centre: Where can we improve the process?","authors":"Grant Punnett ,&nbsp;Melissa Perry ,&nbsp;Charlotte Eastwood ,&nbsp;Laura Green ,&nbsp;Florian Walter ,&nbsp;Janelle Yorke","doi":"10.1016/j.ejon.2024.102762","DOIUrl":"10.1016/j.ejon.2024.102762","url":null,"abstract":"<div><h3>Purpose</h3><div>In decisions relating to cancer treatment, the risks and benefits of treatment and the patient's preferences must be considered to ensure concordance with goals of care. Shared decision making (SDM) can facilitate these discussions and is associated with reduced decision conflict. This study aimed to characterise decision making for advanced cancer patients at a UK tertiary cancer centre and identify who may be at risk of suboptimal SDM and increased decision conflict.</div></div><div><h3>Methods</h3><div>Participants completed the SDM-Q-9, decision conflict and decision self-efficacy scale following a consultation where an advanced cancer treatment decision was made. Pearson's chi-square test identified patient characteristics associated with SDM-Q-9, decision self-efficacy and decision conflict score categories; odds ratios were calculated to determine which patients were at increased probability of experiencing suboptimal SDM, low decision self-efficacy or high decision conflict.</div></div><div><h3>Results</h3><div>Participant's (n = 211) scores indicated predominantly high SDM, high decision self-efficacy and low decision conflict. Patient gender and the presence of an informal caregiver in consultation were significantly associated with SDM-Q-9 score category (p &gt; 0.05). Female patients (OR = 2.466, 95% CI: 1.223–4.974) and those attending consultations alone (OR = 0.440, 95% CI: 0.222–0.874) had greater odds of reporting lower SDM scores.</div></div><div><h3>Conclusion</h3><div>High SDM scores indicate either effective SDM behaviours or satisfaction with care biasing responses. Greater support to engage with SDM is required for female patients and those who attend alone in advanced cancer treatment decision consultations.</div></div>","PeriodicalId":51048,"journal":{"name":"European Journal of Oncology Nursing","volume":"74 ","pages":"Article 102762"},"PeriodicalIF":2.7,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142973129","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A multi-center study of symptoms in patients with esophageal cancer postoperatively: A networking analysis","authors":"Furong Chen ,&nbsp;Zhenrong Shen ,&nbsp;Ying Xiong ,&nbsp;Yingting Jiang ,&nbsp;Dan Zhou ,&nbsp;Junchen Guo ,&nbsp;Hui Huang ,&nbsp;M. Tish Knobf ,&nbsp;Zengjie Ye","doi":"10.1016/j.ejon.2025.102784","DOIUrl":"10.1016/j.ejon.2025.102784","url":null,"abstract":"<div><h3>Purpose</h3><div>This study aimed to explore symptom clusters and the inter-relationship of symptoms in esophageal cancer (EC) patients during the first week after surgery.</div></div><div><h3>Methods</h3><div>A cross-sectional survey across multiple centers was carried out using the EORTCQLQ-OES18. Patients with esophageal cancer within a week post-surgery were recruited from the “Be Resilient to Cancer” project in Guangdong, Hunan, and Sichuan provinces between January and September 2024. Exploratory factor analysis with a priori algorithm was used to identify symptom clusters and network analysis was employed to recognize the relationship among core and bridge symptoms.</div></div><div><h3>Results</h3><div>The sample consisted of 501 patients with esophageal cancer, who were predominantly male (83%), married (93%) and 57% were ≥60 years. Three symptom clusters were identified: “reflux-pain”, “eating”, and “dysphagia-dry mouth”. Acid or bile coming up (support = 40.1%, confidence = 1, lift = 2.53), eating difficulties (support = 40.1%, confidence = 0.990, lift = 2.408) and dry mouth (support = 42.9%, confidence = 0.808, lift = 1.298) were marked as sentinel symptoms for these clusters, respectively. Acid indigestion or heartburn was identified as the core symptom (EI = 1.142 without covariates and EI = 1.153 with covariates), and dry mouth served as the bridge symptoms (EI = 0.63 and EI = 0.656).</div></div><div><h3>Conclusions</h3><div>Addressing acid or bile coming up, eating difficulties, dry mouth are imperative to help relief symptom burden at the cluster level. Furthermore, targeting acid indigestion and heartburn are crucial to break the chains among different symptom clusters.</div></div>","PeriodicalId":51048,"journal":{"name":"European Journal of Oncology Nursing","volume":"74 ","pages":"Article 102784"},"PeriodicalIF":2.7,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143015361","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Two sides of the same coin-sexuality from the perspective of women diagnosed with breast cancer and their partners: A qualitative study","authors":"Merve Işık ,&nbsp;Sultan Özkan Şat ,&nbsp;Bengüsu Tümer","doi":"10.1016/j.ejon.2025.102783","DOIUrl":"10.1016/j.ejon.2025.102783","url":null,"abstract":"<div><h3>Purpose</h3><div>After the diagnosis of breast cancer, women's sexuality becomes complex, and the sexual lives of couples are strongly affected by the treatment process of the disease. The aim of this study is to determine the perceptions, experiences, expectations, and needs related to sexuality from the perspective of women diagnosed with breast cancer and their partners.</div></div><div><h3>Method</h3><div>In this study, a descriptive qualitative design based on a thematic analysis approach was used. The data were collected through individual semi-structured interviews with women diagnosed with breast cancer (n = 22) and their partners (n = 14). The thematic analysis approach was used to analyse the data.</div></div><div><h3>Results</h3><div>The main themes of this study that came out from both the patients' and partners' perspectives were ‘suspension (postponement) of sexual life’ and ‘unmet need for care related to sexuality’. The main themes consist of four sub-themes: ‘changes in sexual dynamics’, ‘unsatisfied sexuality’, ‘barriers to accessing information and support’, and ‘demand for individualised and tailored comprehensive counselling’.</div></div><div><h3>Conclusion</h3><div>Women with breast cancer and their partners were found to have difficulty in asking for help about sexuality and to postpone their sexual lives. Findings of the present study suggest that sexual counselling is of critical importance at every stage of the breast cancer treatment process, and the patients and their partners need a culturally sensitive, individualised care thereof and expect a continuous support.</div></div>","PeriodicalId":51048,"journal":{"name":"European Journal of Oncology Nursing","volume":"74 ","pages":"Article 102783"},"PeriodicalIF":2.7,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143015563","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Symptoms among patients with breast cancer undergoing endocrine therapy: Application of latent profile analysis and network analysis","authors":"Xiaoge He ,&nbsp;Chunlei Liu ,&nbsp;Huanxi Li ,&nbsp;Wei Wang ,&nbsp;Mengying Sun ,&nbsp;Yanjuan Lu ,&nbsp;Yanru Song ,&nbsp;Qian Lu","doi":"10.1016/j.ejon.2025.102797","DOIUrl":"10.1016/j.ejon.2025.102797","url":null,"abstract":"<div><h3>Purpose</h3><div>To identify the subgroups and symptom networks associated with endocrine therapy in patients with breast cancer.</div></div><div><h3>Methods</h3><div>This study was a cross-sectional design using convenience sampling to select patients from a tertiary hospital in China. A total of 406 patients were invited to complete demographic and clinical questionnaires and the Chinese Breast Cancer Prevention Trial Symptom Scale was used to assess their symptoms. Latent profile analysis was used to classify the symptom subgroups of patients with breast cancer undergoing endocrine therapy. Univariate and binary multivariate logistic regression analyses were used to analyze the influence of these factors on different subgroups. Network analysis was used to identify the core symptoms of different subgroups.</div></div><div><h3>Results</h3><div>The analysis revealed two distinct subgroups: low symptom distress (74%; Class 1) and high symptom distress (26%; Class 2). Patients who were older, had a lower monthly family income per capita, and had not received radiotherapy were more likely to belong to Class 2. Furthermore, the network analysis results revealed that “difficulty concentrating” was a core symptom of the entire sample. The core symptom for Class 1 was “lack of energy,” and the core symptom for Class 2 was “joint pain.”</div></div><div><h3>Conclusion</h3><div>The symptoms of patients with breast cancer undergoing endocrine therapy were heterogeneous. Different subgroups exhibited different core symptoms. Therefore, targeted interventions should be provided according to the characteristics of the different symptom subgroups and their core symptoms to achieve precise and effective symptom management.</div></div>","PeriodicalId":51048,"journal":{"name":"European Journal of Oncology Nursing","volume":"74 ","pages":"Article 102797"},"PeriodicalIF":2.7,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143015640","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A feasibility study of a coping-focused, couple-based family resilience intervention (CCFRI) in supporting couples experiencing colorectal cancer","authors":"Xiaoke Qiu ,&nbsp;Can Wang ,&nbsp;Yi Zhang ,&nbsp;Jiayu Mao ,&nbsp;Xueli Yang ,&nbsp;Jie Zhao ,&nbsp;Yi Lin ,&nbsp;Qiuping Li","doi":"10.1016/j.ejon.2025.102821","DOIUrl":"10.1016/j.ejon.2025.102821","url":null,"abstract":"<div><h3>Purpose</h3><div>Colorectal cancer patients and their spousal caregivers possess the potential to build family resilience and navigate the challenges of the cancer journey. However, few intervention studies have focused on enhancing family resilience among colorectal cancer couples. This study aimed to evaluate the feasibility, acceptability, and preliminary effects of a coping-focused, couple-based family resilience intervention guided by the Walsh Family Resilience Model.</div></div><div><h3>Methods</h3><div>A one-group, six-week pre- and post-intervention study was conducted. Six intervention sessions were delivered either face-to-face or by telephone. Quantitative data were collected using self-report questionnaires assessing family resilience, hope, family sense of coherence, spiritual well-being, perceived social support, and couple communication quality. Qualitative data were gathered through semi-structured interviews with open-ended questions and note-taking.</div></div><div><h3>Results</h3><div>A total of 24 colorectal cancer patient-spousal caregiver dyads were initially recruited for the intervention, but only 19 couples completed all six intervention sessions. Feasibility outcomes indicated a couple recruitment rate of 68.6% and a retention rate of 79.2%. Small to moderate improvements were identified in family resilience, hope, family sense of coherence, perceived social support, and couple communication quality, though spiritual well-being showed limited change. The majority of participants were satisfied with the intervention and provided valuable suggestions for future improvements.</div></div><div><h3>Conclusions</h3><div>This study showed that the coping-focused, couple-based family resilience intervention may effectively support colorectal cancer couples, improving adaptation and coping. Future research with larger samples is needed to confirm long-term effects and further refine intervention components.</div></div>","PeriodicalId":51048,"journal":{"name":"European Journal of Oncology Nursing","volume":"75 ","pages":"Article 102821"},"PeriodicalIF":2.7,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143324179","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Profiles of chemotherapy-induced peripheral neuropathy in breast cancer patients undergoing taxane-based chemotherapy: A latent class analysis","authors":"Ruo-lin Li ,&nbsp;Li-xiao Bai ,&nbsp;Yu Liu ,&nbsp;Ai-ling Yang ,&nbsp;Lu Chen ,&nbsp;Fu-yun Zhao ,&nbsp;Ling Zhang ,&nbsp;Jun-E Liu","doi":"10.1016/j.ejon.2024.102758","DOIUrl":"10.1016/j.ejon.2024.102758","url":null,"abstract":"<div><h3>Purpose</h3><div>This study aimed to identify the potential subgroups of chemotherapy-induced peripheral neuropathy (CIPN) in breast cancer patients undergoing taxane-based chemotherapy and examine the association of the latent subtype with patient characteristics.</div></div><div><h3>Methods</h3><div>This multi-center, cross-sectional investigation was conducted between April 2022 and March 2023. CIPN was evaluated using the Functional Assessment of Cancer Therapy/Gynecologic Oncology Group-Neurotoxicity scale. Latent class analysis was employed to identify distinct CIPN subgroups, and multinomial logistic regression was used to analyze the associations between these subgroups and patient characteristics.</div></div><div><h3>Results</h3><div>In total, 397 individuals were categorized into three subgroups: high symptoms with high dysfunction (Class 1; 25.4%), moderate symptoms with low dysfunction (Class 2; 39.2%), and low symptoms with low dysfunction (Class 3; 35.3%). Taxane type, chemotherapy cycles, fatigue, β-blocker use, and depression were significant predictors of the subgroups (<em>P</em> &lt; .05).</div></div><div><h3>Conclusion</h3><div>CIPN symptoms in breast cancer patients are heterogeneous. Significant factors for the latent subgroups included taxane type, chemotherapy cycles, β-blocker use, fatigue, and depression. Identifying different subgroups of chemotherapy-induced peripheral neuropathy would help develop interventions tailored to the patients.</div></div>","PeriodicalId":51048,"journal":{"name":"European Journal of Oncology Nursing","volume":"74 ","pages":"Article 102758"},"PeriodicalIF":2.7,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142822953","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Navigating specific targets of breast cancer symptoms: An innovative computer-simulated intervention analysis","authors":"Minyu Liang ,&nbsp;Yichao Pan ,&nbsp;Jingjing Cai ,&nbsp;Ying Xiong ,&nbsp;Yanjun Liu ,&nbsp;Lisi Chen ,&nbsp;Min Xu ,&nbsp;Siying Zhu ,&nbsp;Xiaoxiao Mei ,&nbsp;Tong Zhong ,&nbsp;M. Tish Knobf ,&nbsp;Zengjie Ye","doi":"10.1016/j.ejon.2024.102708","DOIUrl":"10.1016/j.ejon.2024.102708","url":null,"abstract":"<div><h3>Purpose</h3><div>To pinpoint optimal interventions by dissecting the complex symptom interactions, encompassing both their static and temporal dimensions.</div></div><div><h3>Methods</h3><div>The study incorporated a cross-sectional survey utilizing the MD Anderson Symptom Inventory. Participants with breast cancer undergoing chemotherapy were recruited from the “Be Resilient to Breast Cancer” from April 2023 to June 2024. Static symptom interrelationships were elucidated using undirected and Bayesian network models, complemented by an exploration of their dynamic counterparts through computer-simulated interventions.</div></div><div><h3>Results</h3><div>The study included 602 patients with breast cancer. Both undirected networks and computer-simulated interventions concurred on the symptoms of distress and fatigue as optimal alleviation targets. The Bayesian network and computer-simulated interventions both emphasized “shortness of breath” as preventive care. Notably, Distress appeared to be the most effective target for interventions, and compared to fatigue (decreasing score = 1.84–2.20, decreasing prevalence = 14.2–16.7%). Conversely, disturbed sleep, despite its high position in Bayesian network, had no propelling effects on increasing the network's overall symptom activity levels (increasing score&lt;1).</div></div><div><h3>Conclusions</h3><div>Computer-simulated intervention integrating with traditional network analysis can improve intervention precision and efficacy by prioritizing individual symptom impacts, both statically and dynamically.</div></div>","PeriodicalId":51048,"journal":{"name":"European Journal of Oncology Nursing","volume":"74 ","pages":"Article 102708"},"PeriodicalIF":2.7,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142781855","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"How symptom distress mediates the relationship between individual differences and perceived controllability among women with gynecologic cancer","authors":"Fen-He Lin ,&nbsp;Jong-Long Guo ,&nbsp;Hsiao-Pei Hsu ,&nbsp;Shu-Fen Chen ,&nbsp;Hsin-Jui Lu ,&nbsp;Chiu-Ping Chuang ,&nbsp;Chiu-Mieh Huang","doi":"10.1016/j.ejon.2024.102769","DOIUrl":"10.1016/j.ejon.2024.102769","url":null,"abstract":"<div><h3>Purpose</h3><div>This study aims to investigate the individual differences in perceived controllability among women with gynecologic cancer who are undergoing chemotherapy. We also examined the mediating effect of symptom distress on the relationship between individual differences and perceived controllability.</div></div><div><h3>Methods</h3><div>This cross-sectional study employs purposive sampling; data were collected via self-reported questionnaires. In total, 170 women completed the survey. Structural equation modeling was used to examine the proposed hypotheses of the mediating effect of symptom distress.</div></div><div><h3>Results</h3><div>Results revealed that individual differences in age (r = −0.20, <em>p</em> &lt; .05), education (t = −2.24, <em>p</em> &lt; .05), employment (t = −2.05, <em>p</em> &lt; .05), cancer stage (t = 2.35, <em>p</em> &lt; .05), and number of chemotherapy sessions in the past three months (r = −0.16, <em>p</em> &lt; .05) were significantly associated with perceived treatment control. Physical, but not psychological, symptom distress fully mediated the relationship between individual differences and perceived controllability. Participants who perceived financial distress (β = 0.179, <em>p</em> &lt; .05) and those who had undergone a higher number of chemotherapy sessions within the past three months (β = 0.216, <em>p</em> &lt; .05) experienced greater physical symptom distress. Additionally, those who experienced greater physical symptom distress perceived lower personal control (β = −0.199, <em>p</em> &lt; .05) and treatment control (β = −0.217, <em>p</em> &lt; .05).</div></div><div><h3>Conclusions</h3><div>Understanding the mediating effects of symptom distress on the relationship between individual differences and perceived controllability can enhance our knowledge of the mechanisms of illness acceptance, which significantly contributes to illness adaptation among women with gynecologic cancer.</div></div>","PeriodicalId":51048,"journal":{"name":"European Journal of Oncology Nursing","volume":"74 ","pages":"Article 102769"},"PeriodicalIF":2.7,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142973153","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}