Encephale-Revue De Psychiatrie Clinique Biologique et Therapeutique最新文献

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Suicidal thoughts and behavior of adolescents with depression in Reunion Island - evolution before and after the initial Covid-19 lockdown. 留尼汪岛抑郁症青少年的自杀想法和行为--Covid-19 封锁行动前后的演变。
IF 2.7 4区 医学
Encephale-Revue De Psychiatrie Clinique Biologique et Therapeutique Pub Date : 2024-05-31 DOI: 10.1016/j.encep.2024.02.006
Josee Aoun, Coline Copin, Miléna Portelette, Massimiliano Orri, Michel Spodenkiewicz
{"title":"Suicidal thoughts and behavior of adolescents with depression in Reunion Island - evolution before and after the initial Covid-19 lockdown.","authors":"Josee Aoun, Coline Copin, Miléna Portelette, Massimiliano Orri, Michel Spodenkiewicz","doi":"10.1016/j.encep.2024.02.006","DOIUrl":"https://doi.org/10.1016/j.encep.2024.02.006","url":null,"abstract":"<p><strong>Background: </strong>The number of patients consulting with suicidal thoughts and behavior in the health care centers have increased since the Covid-19 pandemic. This increase has been particularly important among adolescents. Most often these patients are diagnosed with anxiety or depressive symptoms. We only have a limited amount of information on depression and STB in adolescents since epidemiological monitoring in health care institutions is based on computerized coding derived from ICD-10. This coding system is very specific for the different forms of depression yet fails to provide accurate coding for suicidal thoughts and behavior. The objectives of this study were to compare the numbers of adolescents with depression who were admitted with suicidal thoughts and behavior before and after the initial Covid-19 lockdown and to highlight possible gender disparities.</p><p><strong>Methods: </strong>Patients' medical charts for this retrospective research were obtained from the Department of Adolescent Psychiatry at the University Hospital Centre of Reunion Island, manually screened, and then analyzed. We included all adolescents diagnosed with depression who had had their first consultation between January 1, 2019 and July 31, 2021. The number of patients presenting suicidal thoughts, self-harm and suicide attempts were compared before and after the initial Covid-19 lockdown.</p><p><strong>Results: </strong>Three hundred and sixty-one adolescents diagnosed with depression participated in the study (33.5% males, 66.5% females). Their average age was 16 (SD=1.7). The number of admitted patients increased from 9 to 16 new adolescents with depression and STB each month between the period before and after the first lockdown, with a large proportion of female patients (increase of 74.1%).</p><p><strong>Conclusion: </strong>This study showed an increase in the number of adolescents consulting for suicidal thoughts or behavior in an adolescent psychiatry department in Reunion Island after the initial Covid-19 lockdown. They were mainly female. This increase has strained an already overburdened mental health system by doubling the number of adolescents that each health care provider has had to help which increases the risk of inadequate care by rapidly increasing the workload but with constant resources.</p>","PeriodicalId":51042,"journal":{"name":"Encephale-Revue De Psychiatrie Clinique Biologique et Therapeutique","volume":null,"pages":null},"PeriodicalIF":2.7,"publicationDate":"2024-05-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141187220","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Prevalence of benzodiazepines use during pregnancy in Lebanon. 黎巴嫩怀孕期间使用苯并二氮杂卓的普遍程度。
IF 2.7 4区 医学
Encephale-Revue De Psychiatrie Clinique Biologique et Therapeutique Pub Date : 2024-05-31 DOI: 10.1016/j.encep.2024.02.009
Juliana Sargi, Charline Hachem, Sami Richa, Chanel El Amil
{"title":"Prevalence of benzodiazepines use during pregnancy in Lebanon.","authors":"Juliana Sargi, Charline Hachem, Sami Richa, Chanel El Amil","doi":"10.1016/j.encep.2024.02.009","DOIUrl":"https://doi.org/10.1016/j.encep.2024.02.009","url":null,"abstract":"<p><p>Pregnancy is a period of heightened risk period for many psychiatric disorders, particularly anxiety disorders. However, there is limited knowledge regarding the usage of psychotropic medications during pregnancy. Over the past decade there has been a notable increase in the use of medications during pregnancy, with benzodiazepines being the primary choice for alleviating anxiety. It is important to note, though, that benzodiazepines have been associated with various risks for both pregnancy and newborns. In Lebanon, to date, there has been no study estimating the prevalence of the use of benzodiazepines during pregnancy. Our study aims to find the prevalence of benzodiazepines use in a population of pregnant women in Hôtel-Dieu Hospital, a tertiary care center in Beirut, and the medical center of Saint-Joseph University and to compare our results to international literature. To accomplish our objectives we administered questionnaires to over two hundred women who had recently given birth in the gynecology department. These forms encompassed inquiries about benzodiazepine consumption, as well as various medical and socio demographic details. In total, we interviewed 225 women who gave birth at the Hôtel-Dieu de France between the months of December 2019 and February 2020 and between the months of February 2021 and October 2021 in the gynecology department. The questionnaires included socio demographic, medical, and psychiatric information as well as questions about the use of benzodiazepines. We found a significantly lower prevalence of benzodiazepine use among these women compared to the figures reported in international literature. The approval of the ethics committee was obtained on December 19, 2019 after making sure that this study raised no ethical objections. (File number: CEHDF 1533).</p>","PeriodicalId":51042,"journal":{"name":"Encephale-Revue De Psychiatrie Clinique Biologique et Therapeutique","volume":null,"pages":null},"PeriodicalIF":2.7,"publicationDate":"2024-05-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141187214","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Somatic conversion in adolescents: A case study. 青少年的躯体转换:个案研究。
IF 2.7 4区 医学
Encephale-Revue De Psychiatrie Clinique Biologique et Therapeutique Pub Date : 2024-05-31 DOI: 10.1016/j.encep.2024.02.010
Yassine Benhaddouch, Françoise Dumont, Naima Boukhalfa, Amine Bout, Chadya Aarab, Rachid Aalouane
{"title":"Somatic conversion in adolescents: A case study.","authors":"Yassine Benhaddouch, Françoise Dumont, Naima Boukhalfa, Amine Bout, Chadya Aarab, Rachid Aalouane","doi":"10.1016/j.encep.2024.02.010","DOIUrl":"https://doi.org/10.1016/j.encep.2024.02.010","url":null,"abstract":"","PeriodicalId":51042,"journal":{"name":"Encephale-Revue De Psychiatrie Clinique Biologique et Therapeutique","volume":null,"pages":null},"PeriodicalIF":2.7,"publicationDate":"2024-05-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141187218","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Factors associated with sexual dysfunction in patients with bipolar disorder. 躁郁症患者性功能障碍的相关因素。
IF 2.7 4区 医学
Encephale-Revue De Psychiatrie Clinique Biologique et Therapeutique Pub Date : 2024-05-31 DOI: 10.1016/j.encep.2024.03.008
Mona Lagha, Wided Homri, Naouel Dhaouadi, Sarra Rouached
{"title":"Factors associated with sexual dysfunction in patients with bipolar disorder.","authors":"Mona Lagha, Wided Homri, Naouel Dhaouadi, Sarra Rouached","doi":"10.1016/j.encep.2024.03.008","DOIUrl":"https://doi.org/10.1016/j.encep.2024.03.008","url":null,"abstract":"<p><strong>Objectives: </strong>The aims of our study were to assess the sexual function in men with bipolar disorder type 1 in remission and to determine the various sociodemographic, clinical and therapeutic factors associated with sexual dysfunction.</p><p><strong>Methods: </strong>We conducted a cross-sectional study over an 18-month period (January 2020-June 2021) in which we included men followed up for bipolar disorder type 1 in the euthymic phase strictly defined by a score <8 on the Young Mania Rating Scale and a score ≤7 on the Hamilton Depression Rating Scale. Sexual function was assessed using the Arizona Sexual Experiences Scale (Asex) in its Arabic-validated version.</p><p><strong>Results: </strong>Sixty patients were included in the study. The mean age was 42.5 (SD=11.1) years. Among the patients, 68% had sexual dysfunction according to the total score of the Asex scale. According to univariate analysis, several factors were significantly associated with sexual dysfunction in patients with bipolar disorder type 1: age (P=0.001), total number of hospitalizations for thymic relapse (P=0.015), total number of depressive episodes (P=0.006) and depressive dominant polarity (P=0.046). The factors identified as modifying sexuality according to the total score of the Asex scale by multivariate analysis were age at first antipsychotic prescription: P=0.01; ORa=1.109; 95% CI [1.021-1.206] and number of hospitalizations for thymic relapse: P=0.015; ORa=1.259; 95% CI [1.046-1.546].</p><p><strong>Conclusion: </strong>Studies assessing factors associated with sexual dysfunction in patients with bipolar disorder type 1 in euthymia were mostly concerned with the effects of psychotropic drugs on sexual function, with factors inherent in bipolar illness itself not widely addressed in the literature. According to the results of our study, sexual dysfunction in patients with bipolar disorder in the euthymic phase is frequent and significantly associated with clinical factors inherent in the bipolar illness itself and its course.</p>","PeriodicalId":51042,"journal":{"name":"Encephale-Revue De Psychiatrie Clinique Biologique et Therapeutique","volume":null,"pages":null},"PeriodicalIF":2.7,"publicationDate":"2024-05-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141187211","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A recovery-oriented day hospital in psychiatry: A springboard for reintegration. 精神病学中以康复为导向的日间医院:重新融入社会的跳板。
IF 2.7 4区 医学
Encephale-Revue De Psychiatrie Clinique Biologique et Therapeutique Pub Date : 2024-05-23 DOI: 10.1016/j.encep.2024.02.004
Ghita Dadi, Lucie Venet-Kelma, Mauricette Mendy, Laurence Kern, Pierre-Alain Hauseux, Valérie Dauriac-Le Masson, Raphaël Gaillard, Marion Plaze, Yannick Morvan, Mona Moualla, Isabelle Amado
{"title":"A recovery-oriented day hospital in psychiatry: A springboard for reintegration.","authors":"Ghita Dadi, Lucie Venet-Kelma, Mauricette Mendy, Laurence Kern, Pierre-Alain Hauseux, Valérie Dauriac-Le Masson, Raphaël Gaillard, Marion Plaze, Yannick Morvan, Mona Moualla, Isabelle Amado","doi":"10.1016/j.encep.2024.02.004","DOIUrl":"https://doi.org/10.1016/j.encep.2024.02.004","url":null,"abstract":"<p><p>Psychiatric disorders are common and can cause psychological disabilities. While the creation of day hospitals (DHs) was intended to direct psychiatric care towards community settings, they may have paradoxically contributed to a form of chronicity. Furthermore, the heterogeneity and lack of evaluation of care within DHs prevent the availability needed to collect objective data on users outcomes. In this article, we aim to describe and measure the effects of a transformation of practice within a sector-based DH initially focused on traditional institutional psychiatry towards a rehabilitation model of care which offers different therapeutic tools, structured in three stages, and whose main objective is professional integration. This retrospective mirror study compares, before and after the transformation of this DH, several indicators including the rate of professional integration and its maintenance after two years. We found that this psychosocial rehabilitation model for care allowed a very clear increase in the professional integration rate and its maintenance at two years while reducing the length of stay to around 18 months. These promising results therefore highlight the pivotal role of DHs as \"stepping stones\" in addressing psychological disabilities towards recovery.</p>","PeriodicalId":51042,"journal":{"name":"Encephale-Revue De Psychiatrie Clinique Biologique et Therapeutique","volume":null,"pages":null},"PeriodicalIF":2.7,"publicationDate":"2024-05-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141094392","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Violent video gaming among French adolescents: Impact on mental health by gender. 法国青少年的暴力视频游戏:不同性别对心理健康的影响
IF 2.7 4区 医学
Encephale-Revue De Psychiatrie Clinique Biologique et Therapeutique Pub Date : 2024-05-15 DOI: 10.1016/j.encep.2024.02.001
Mireille Cosquer, Clara Finck, Catherine Jousselme, Aline Lefebvre
{"title":"Violent video gaming among French adolescents: Impact on mental health by gender.","authors":"Mireille Cosquer, Clara Finck, Catherine Jousselme, Aline Lefebvre","doi":"10.1016/j.encep.2024.02.001","DOIUrl":"https://doi.org/10.1016/j.encep.2024.02.001","url":null,"abstract":"<p><strong>Background: </strong>Nowadays, video games are very popular among teenagers. This popularity generates concerns, whether in the media, among families or among the scientific community, who wonder about their potential harmful effects. The aim of this study was to assess the association between different types of use of video games (absence of use, use of violent video games, use of non-violent video games) and mental health and aggression.</p><p><strong>Methods: </strong>Data was drawn from a French cross-sectional study entitled \"Portrait d'Adolescents\" which included 15,235 adolescents using anonymous self-administered questionnaires. We defined three groups of use of video games (absence of use, use of violent video games, use of non-violent video games) and explored the association with mental health indicators among boys and girls.</p><p><strong>Results: </strong>The group categorized as \"non-gamers\" consisted of 1288 adolescents (8.5%), while the \"non-violent video gamers\" group comprised 8380 adolescents (55.5%) and the \"violent video gamers\" group included 5430 participants (36%). Among adolescent boys, there was no observed association between responses to mental health-related questions and the type of video game playing. However, in the \"violent video gamers\" group, a higher percentage of boys (6.8%) reported engaging in self-harm behaviors (p=0.001). In contrast, in the \"non-violent video gamers\" group, a lower proportion of boys (9.4%) reported participating in dangerous games (p<0.0001). For girls, the \"violent video gamers\" group exhibited a higher proportion of responses indicating poorer mental health across all explored items: 22.8% reported a history of suicide attempts (p<0.0001), 22.3% reported depression (p<0.0001), 17.8% reported self harm (p<0.0001), and 11.2% reported participating in dangerous game (p<0.0001).</p><p><strong>Conclusion: </strong>Violent video games appear to be associated with varying behaviors depending on the gender of adolescents, and notably contribute to much poorer mental health among adolescent girls.</p>","PeriodicalId":51042,"journal":{"name":"Encephale-Revue De Psychiatrie Clinique Biologique et Therapeutique","volume":null,"pages":null},"PeriodicalIF":2.7,"publicationDate":"2024-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140960698","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
L’anorexie mentale : une addiction ? Application du modèle addictologique aux troubles du comportement alimentaire. Une revue narrative commentée [神经性厌食症:成瘾?成瘾模式在饮食失调症中的应用。叙事性评论综述]。
IF 1.2 4区 医学
Encephale-Revue De Psychiatrie Clinique Biologique et Therapeutique Pub Date : 2024-05-15 DOI: 10.1016/j.encep.2024.03.002
{"title":"L’anorexie mentale : une addiction ? Application du modèle addictologique aux troubles du comportement alimentaire. Une revue narrative commentée","authors":"","doi":"10.1016/j.encep.2024.03.002","DOIUrl":"10.1016/j.encep.2024.03.002","url":null,"abstract":"<div><h3>Objectives</h3><div>Addiction offers a framework for the understanding of eating disorders, particularly those characterized by hyperphagia, with growing interest in food addiction. However, the application of the addiction model to anorexia nervosa remains more controversial. In this commented narrative review, we examine and discuss the addictive features of anorexia nervosa.</div></div><div><h3>Methods</h3><div>Commented narrative review of the literature.</div></div><div><h3>Results</h3><div>Anorexia nervosa could be the consequence of the loss of control of several objects of positive reinforcement: food restriction, physical hyperactivity, and food itself. Craving has been little studied in the field of eating disorders. When investigated, studies mainly focus on food cravings and tend to highlight food cravings that are inversely correlated with the restrictive nature of the disorder. This would thus be less found in anorexia nervosa, in which it is nevertheless reported. The existence of a pre-existing food craving, or its appearance secondary to food restriction, is currently under discussion. In the meantime, the question of a craving for food restriction, underpinned by the gratifying effect of fasting, is raised.</div></div><div><h3>Conclusions</h3><div>The management of eating disorders has its place within the addiction care sectors. An integrative approach should be favored, for anorexia nervosa, combining, on the one hand, classic nutritional care, and, on the other hand, care within the framework of addiction treatment. Finally, in people with an eating disorder, the search for an addiction to food, food restriction and physical activity, including a systematic assessment of craving, should be systematized.</div></div>","PeriodicalId":51042,"journal":{"name":"Encephale-Revue De Psychiatrie Clinique Biologique et Therapeutique","volume":null,"pages":null},"PeriodicalIF":1.2,"publicationDate":"2024-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S001370062400068X/pdfft?md5=0130fcb3d26ceb60e00127c562f3a96c&pid=1-s2.0-S001370062400068X-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140960696","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Barriers and facilitators to achieving employment in mainstream settings in adults with autism spectrum disorder without intellectual developmental disorders: A scoping review. 无智力发育障碍的自闭症谱系障碍成人在主流环境中实现就业的障碍和促进因素:范围综述。
IF 2.7 4区 医学
Encephale-Revue De Psychiatrie Clinique Biologique et Therapeutique Pub Date : 2024-05-09 DOI: 10.1016/j.encep.2024.02.012
Sylvie Holc, Alexandre Yailian, Eric Pernon, Amaria Baghdadli
{"title":"Barriers and facilitators to achieving employment in mainstream settings in adults with autism spectrum disorder without intellectual developmental disorders: A scoping review.","authors":"Sylvie Holc, Alexandre Yailian, Eric Pernon, Amaria Baghdadli","doi":"10.1016/j.encep.2024.02.012","DOIUrl":"https://doi.org/10.1016/j.encep.2024.02.012","url":null,"abstract":"<p><p>Autistic people without Intellectual Developmental Disorders (IDD) have a significantly lower employment rate compared to the general population even though employment favors social integration and quality of life.</p><p><strong>Aims: </strong>To examine the barriers and facilitators to employability in mainstream settings for autistic adults without intellectual disability.</p><p><strong>Methods: </strong>Following the scoping review guidelines, we searched the Cochrane, PubMed and PsycINFO databases for references published between 01/01/2000 to 01/08/2023.</p><p><strong>Results: </strong>A review of the 44 identified articles suggests the existence of multiple individual and environmental factors influencing job access and retention.</p><p><strong>Conclusions: </strong>This is the first review to assess the facilitators and barriers to employment support for autistic people without intellectual disability. The results underline the need for studying strategies to promote access to employment and job retention for autistic people. Future research should explore the mediating and moderating factors leading to the improvement of employability of autistic people WIDD.</p>","PeriodicalId":51042,"journal":{"name":"Encephale-Revue De Psychiatrie Clinique Biologique et Therapeutique","volume":null,"pages":null},"PeriodicalIF":2.7,"publicationDate":"2024-05-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140905021","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Functions of binge eating: Cross-cultural adaptation to Brazilian Portuguese 暴饮暴食的功能:跨文化适应巴西葡萄牙语。
IF 1.2 4区 医学
Encephale-Revue De Psychiatrie Clinique Biologique et Therapeutique Pub Date : 2024-05-09 DOI: 10.1016/j.encep.2024.03.004
{"title":"Functions of binge eating: Cross-cultural adaptation to Brazilian Portuguese","authors":"","doi":"10.1016/j.encep.2024.03.004","DOIUrl":"10.1016/j.encep.2024.03.004","url":null,"abstract":"","PeriodicalId":51042,"journal":{"name":"Encephale-Revue De Psychiatrie Clinique Biologique et Therapeutique","volume":null,"pages":null},"PeriodicalIF":1.2,"publicationDate":"2024-05-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140905026","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Neuroimaging correlates of classical psychedelics effects: A systematic review]. [经典迷幻药效应的神经影像学相关性:系统综述]。
IF 2.7 4区 医学
Encephale-Revue De Psychiatrie Clinique Biologique et Therapeutique Pub Date : 2024-05-08 DOI: 10.1016/j.encep.2024.02.007
Doriane Dost, Amine Benyamina, Laurent Karila
{"title":"[Neuroimaging correlates of classical psychedelics effects: A systematic review].","authors":"Doriane Dost, Amine Benyamina, Laurent Karila","doi":"10.1016/j.encep.2024.02.007","DOIUrl":"https://doi.org/10.1016/j.encep.2024.02.007","url":null,"abstract":"<p><strong>Background: </strong>Current scientific literature supports classical psychedelic efficacy in many psychiatric disorders. However, less attention has been given to the neurological effects of these substances. The aim of this medical thesis was to conduct a systematic review examining the neuroimaging correlates of the effects of psychedelics.</p><p><strong>Method: </strong>We performed an electronic research through Medline and Science Direct databases. A comprehensive search yielded 460 articles published up to May 2022. After a cautious screening process, we selected 49 scientific papers for further analysis.</p><p><strong>Results: </strong>Major findings included reduced functional network integration, increased between-network functional connectivity, and expansion of functional connectivity patterns repertoire under psychedelics. Thalamic gating and emotional processing were also impaired. These results positively correlated with symptom improvement in pathological populations.</p><p><strong>Conclusion: </strong>To this day, our knowledge concerning psychedelic effects remains partial. Several neurocognitive theories have been developed in recent years to model psychedelic phenomenology, but no unifying theory has emerged. Studies involving larger populations investigating various psychiatric disorders, including several neuroimaging modalities and considering medium- and long-term effects, would be necessary to deepen current knowledge.</p>","PeriodicalId":51042,"journal":{"name":"Encephale-Revue De Psychiatrie Clinique Biologique et Therapeutique","volume":null,"pages":null},"PeriodicalIF":2.7,"publicationDate":"2024-05-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140900093","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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