Current Problems in Cardiology最新文献

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The top 100 most cited articles in cardiovascular research: A bibliometric perspective 心血管研究中被引用最多的100篇文章:文献计量学视角
IF 3.3 3区 医学
Current Problems in Cardiology Pub Date : 2025-08-25 DOI: 10.1016/j.cpcardiol.2025.103153
Siddig Ibrahim Abdelwahab , Manal Mohamed Elhassan Taha , Abdullah Farasani , Jobran M Moshi , Ahmad Assiri , Saeed Alshahrani , Khaled A Sahli , Hussam M. Shubaily , Waseem Hassan
{"title":"The top 100 most cited articles in cardiovascular research: A bibliometric perspective","authors":"Siddig Ibrahim Abdelwahab ,&nbsp;Manal Mohamed Elhassan Taha ,&nbsp;Abdullah Farasani ,&nbsp;Jobran M Moshi ,&nbsp;Ahmad Assiri ,&nbsp;Saeed Alshahrani ,&nbsp;Khaled A Sahli ,&nbsp;Hussam M. Shubaily ,&nbsp;Waseem Hassan","doi":"10.1016/j.cpcardiol.2025.103153","DOIUrl":"10.1016/j.cpcardiol.2025.103153","url":null,"abstract":"<div><h3>Objective</h3><div>The aim is to analyze the citation dynamics, and research focus of the top 100 most cited cardiovascular research.</div></div><div><h3>Methods</h3><div>Data were retrieved from the Scopus database in January 2025, focusing on journals containing the term “cardio” in their title. Only original research articles and reviews were included. The data were analyzed using VOSviewer and R Studio to assess co-authorship networks, keyword co-occurrence, citation mapping, and citation impact indicators.</div></div><div><h3>Results</h3><div>A total of 100 articles, published between 1967 and 2020, were included in the analysis. These articles had an average of 2,285 citations each. The growth rate of publications was 3.74 %, with an average document age of 20.8 years. Collaboration was extensive, with 1,653 authors contributing to these papers, and 25 % of publications involved international collaboration. Citation analysis showed increasing citation rates over time, with recent papers achieving significant impact in a short period. The top authors, universities, countries, and sources of publication were identified, revealing the global nature of cardiovascular research and its collaborative nature. The title co-words analysis was also performed to understand the main focus of the most cited papers.</div></div><div><h3>Conclusions</h3><div>This study offers a deeper understanding of the most cited cardiovascular research papers, addressing gaps in previous bibliometric studies by providing insights into citation dynamics, author collaborations, and thematic shifts. Future studies should explore the quality of research and expand the scope of bibliometric analyses.</div></div>","PeriodicalId":51006,"journal":{"name":"Current Problems in Cardiology","volume":"50 11","pages":"Article 103153"},"PeriodicalIF":3.3,"publicationDate":"2025-08-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144933731","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Trends in cardiovascular risk in Peru: A 10-year population-based analysis (2015–2024) 秘鲁心血管风险趋势:基于人群的10年分析(2015-2024)
IF 3.3 3区 医学
Current Problems in Cardiology Pub Date : 2025-08-20 DOI: 10.1016/j.cpcardiol.2025.103155
Carlos Diaz-Arocutipa MD , Natalia Nombera-Aznaran MD , Vicente Benites-Zapata MD , Pedro Kikushima-Alcantara MD , Percy Herrera-Añazco MD
{"title":"Trends in cardiovascular risk in Peru: A 10-year population-based analysis (2015–2024)","authors":"Carlos Diaz-Arocutipa MD ,&nbsp;Natalia Nombera-Aznaran MD ,&nbsp;Vicente Benites-Zapata MD ,&nbsp;Pedro Kikushima-Alcantara MD ,&nbsp;Percy Herrera-Añazco MD","doi":"10.1016/j.cpcardiol.2025.103155","DOIUrl":"10.1016/j.cpcardiol.2025.103155","url":null,"abstract":"<div><h3>Background</h3><div>Data on national trends in cardiovascular risk in Latin America are limited. We aimed to evaluate changes in estimated 10-year cardiovascular risk in Peru between 2015 and 2024, and assess disparities by sex, age, residence, and region.</div></div><div><h3>Methods</h3><div>We conducted a cross-sectional analysis using nationally representative data from the Peruvian Demographic and Health Survey. Adults aged 40–74 years with complete risk factor data were included. Ten-year cardiovascular risk was estimated using the 2019 WHO non-laboratory prediction charts for Andean Latin America. Trends in mean absolute risk and the proportion of individuals at ≥high risk were assessed using joinpoint regression models, overall and by sex, age group, area of residence, and region.</div></div><div><h3>Results</h3><div>Among 104,617 participants, mean estimated 10-year cardiovascular risk declined from 5% in 2015 to 4.4% in 2024 (average annual percent change [AAPC] −2.3%; 95% C: −3.2 to −1.5). The prevalence of ≥high cardiovascular risk decreased from 10.3% to 8.5% (AAPC −3.2%; 95% CI −5.0 to −1.6). Risk declined significantly among women, younger adults, and both urban and rural populations, but remained unchanged in men and older adults. Regional trends were heterogeneous, with the steepest reductions observed in Amazonas, Ica, and Ayacucho.</div></div><div><h3>Conclusions</h3><div>Although a slight decline in estimated cardiovascular risk was observed in Peru over the past decade, the change may have limited clinical relevance. These trends emphasize the need for stronger, equity-focused efforts to reduce the burden of cardiovascular disease at the national level.</div></div>","PeriodicalId":51006,"journal":{"name":"Current Problems in Cardiology","volume":"50 10","pages":"Article 103155"},"PeriodicalIF":3.3,"publicationDate":"2025-08-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144891900","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Interatrial shunt devices in heart failure with preserved ejection fraction: A meta-analysis of randomized trials 房间分流装置用于保留射血分数的心力衰竭:随机试验的荟萃分析。
IF 3.3 3区 医学
Current Problems in Cardiology Pub Date : 2025-08-20 DOI: 10.1016/j.cpcardiol.2025.103154
Alonzo Armani Prata , Ana Carolina Covre Coan , Megan Coylewright MD, MPH , Julia Marques Fernandes , Eric Shih Katsuyama MD , Christian Ken Fukunaga , Gabriel Scarpioni Barbosa , Pedro Gabriel Scardini , Gioli-Pereira Luciana MD, PhD
{"title":"Interatrial shunt devices in heart failure with preserved ejection fraction: A meta-analysis of randomized trials","authors":"Alonzo Armani Prata ,&nbsp;Ana Carolina Covre Coan ,&nbsp;Megan Coylewright MD, MPH ,&nbsp;Julia Marques Fernandes ,&nbsp;Eric Shih Katsuyama MD ,&nbsp;Christian Ken Fukunaga ,&nbsp;Gabriel Scarpioni Barbosa ,&nbsp;Pedro Gabriel Scardini ,&nbsp;Gioli-Pereira Luciana MD, PhD","doi":"10.1016/j.cpcardiol.2025.103154","DOIUrl":"10.1016/j.cpcardiol.2025.103154","url":null,"abstract":"<div><h3>Background</h3><div>The clinical effect of an iatrogenic interatrial shunt in heart failure with preserved ejection fraction (HFpEF) was based on observational data, wherein decompression of the pressure-overloaded left atrium improved symptoms and hemodynamics. However, the identification of a specific patient population that may benefit remains unclear.</div></div><div><h3>Methods</h3><div>We searched for randomized controlled trials (RCTs) that compared the creation of interatrial shunts versus a sham procedure in patients with HFpEF. The primary outcomes of interest were HF events and Cardiovascular (CV) mortality.</div></div><div><h3>Results</h3><div>Three RCTs were included, encompassing 966 patients, of which 479 (49.5%) were in the interatrial shunt group. The mean age of the participants was 73.2 years, with an average LVEF of 58.7%. Of the 479 patients undergoing interatrial shunt placement, 69% had exercise hemodynamics to assist in selection for therapy. Interatrial shunt therapy in the selected patients showed a trend towards an increased risk of HF events (RR:1.29;95%CI:0.98-1.70;p=0.069) and CV death (RR:2.30;95%CI:0.94-5.59;p=0.067), compared with the sham procedure.</div></div><div><h3>Conclusion</h3><div>In this meta-analysis of patients with HFpEF, interatrial shunt therapy showed a trend towards an increased risk of HF events and CV mortality compared with the sham procedure, with no significant improvement in MACE, quality of life, or rates of MI and stroke/TIA. These findings raise concerns about interatrial shunt therapy for the broader HFpEF population and highlight the need for better patient selection.</div></div>","PeriodicalId":51006,"journal":{"name":"Current Problems in Cardiology","volume":"50 11","pages":"Article 103154"},"PeriodicalIF":3.3,"publicationDate":"2025-08-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144977631","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Peripartum hypertension and neonatal outcomes across races: 2016-2022 围产期高血压和不同种族新生儿结局:2016-2022
IF 3.3 3区 医学
Current Problems in Cardiology Pub Date : 2025-08-20 DOI: 10.1016/j.cpcardiol.2025.103152
Muhammad Shariq Usman MD , Ali Salman MBBS , Eliza Aisha MBBS , Uzair Khan MBBS , Sabina Naz MBBS , Sarah Faisal MBBS , Iqra Yaseen Khan MBBS , Muhammad Hammad Arif MBBS , Neha Mohiuddin MBBS , Ayesha Ali Khan MBBS , Ahson Afzal MBBS , Hamza Janjua MD , Farman Ali MD , Tariq Jamal Siddiqi MD
{"title":"Peripartum hypertension and neonatal outcomes across races: 2016-2022","authors":"Muhammad Shariq Usman MD ,&nbsp;Ali Salman MBBS ,&nbsp;Eliza Aisha MBBS ,&nbsp;Uzair Khan MBBS ,&nbsp;Sabina Naz MBBS ,&nbsp;Sarah Faisal MBBS ,&nbsp;Iqra Yaseen Khan MBBS ,&nbsp;Muhammad Hammad Arif MBBS ,&nbsp;Neha Mohiuddin MBBS ,&nbsp;Ayesha Ali Khan MBBS ,&nbsp;Ahson Afzal MBBS ,&nbsp;Hamza Janjua MD ,&nbsp;Farman Ali MD ,&nbsp;Tariq Jamal Siddiqi MD","doi":"10.1016/j.cpcardiol.2025.103152","DOIUrl":"10.1016/j.cpcardiol.2025.103152","url":null,"abstract":"<div><h3>Background</h3><div>Maternal hypertension, a major pregnancy complication, can adversely affect newborn health. Our study investigated racial/ethnic disparities in neonatal outcomes among hypertensive pregnant women in the US.</div></div><div><h3>Methods</h3><div>Using data from the CDC WONDER Natality database, we conducted a retrospective cohort study focusing on live births to hypertensive mothers from 2016 to 2022. We calculated rates [95% CI] per 1000 live births for NICU admissions, neonatal assisted ventilation, low birth weight, and in-hospital mortality across racial/ethnic groups and regions.</div></div><div><h3>Results</h3><div>We analyzed 2,392,664 live births to hypertensive women. In-hospital neonatal mortality rates were highest in Black American women (BA) (3.6 [3.5, 3.8]). Neonatal assisted ventilation rates were highest in Native Hawaiian/Pacific Islander women (NH/PI) (131.8 [123.4, 140.7]) and low birth weight rates were highest in BA (235.1 [233.9, 236.3]). Across all races, female neonates had a higher rate of low birth weight compared to male neonates, while male neonates had higher incidences of NICU admissions, neonatal assisted ventilation, and in-hospital mortality. The Midwest had the highest rates for NICU admissions in NH/PI (254.2 [217.2, 295.2]), neonatal assisted ventilation in American Indian/Alaska Native women (143.8 [133.2, 155.1]), and in-hospital mortality in BA (4.1 [3.7, 4.5]). The South had the highest rate of low birth weight for BA (244.4 [242.9, 246.0]).</div></div><div><h3>Conclusions</h3><div>Significant racial and regional disparities exist in neonatal outcomes among hypertensive women in the US, with BA mothers experiencing the poorest outcomes. Further research is necessary to develop targeted interventions for high-risk populations.</div></div>","PeriodicalId":51006,"journal":{"name":"Current Problems in Cardiology","volume":"50 10","pages":"Article 103152"},"PeriodicalIF":3.3,"publicationDate":"2025-08-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144896116","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Revisiting type 2 myocardial infarction: Unmet clinical needs 重新审视2型心肌梗死:未满足的临床需求。
IF 3.3 3区 医学
Current Problems in Cardiology Pub Date : 2025-08-07 DOI: 10.1016/j.cpcardiol.2025.103148
Andrea Palermi , Silvio Saraullo , Maria Bernadette Giordano , Fabrizio Ricci , Sabina Gallina , Giulia Renda
{"title":"Revisiting type 2 myocardial infarction: Unmet clinical needs","authors":"Andrea Palermi ,&nbsp;Silvio Saraullo ,&nbsp;Maria Bernadette Giordano ,&nbsp;Fabrizio Ricci ,&nbsp;Sabina Gallina ,&nbsp;Giulia Renda","doi":"10.1016/j.cpcardiol.2025.103148","DOIUrl":"10.1016/j.cpcardiol.2025.103148","url":null,"abstract":"<div><div>Cardiovascular disease is the most common cause of mortality and morbidity worldwide and acute coronary syndrome (ACS) is often the first clinical manifestation. Currently, the diagnosis of acute myocardial infarction (AMI) is based on the fourth universal definition of myocardial infarction (MI), with different subtypes based on their pathophysiological background. While type 1 myocardial infarction (T1MI) is defined by an acute coronary event with plaque disruption and consequent athero-thrombosis, type 2 myocardial infarction (T2MI) is defined as an event due to oxygen demand and supply imbalance, unrelated to acute coronary athero-thrombosis. The differentiation between these two entities is crucial since T1MI benefits from an early invasive approach aimed at myocardial reperfusion, while in T2MI it is critical to focus on the cause of the ischemia mismatch. Furthermore, T2MI is often associated with a poorer prognosis. The presence and severity of coronary artery disease (CAD) may significantly influence the ischemic threshold and the risk of T2MI, as it has been identified as an independent predictor of cardiovascular death and recurrent MI. The key point of contention is determining the presence of CAD in T2MI to identify patients eligible for a reperfusion strategy and to tailor therapy as well as secondary prevention strategies.</div><div>In this narrative review, we aim to highlight the differences in clinical features, imaging, and biomarkers between T1MI and T2MI, emphasizing the role of CAD, in refining the diagnostic-therapeutic algorithm in T2MI.</div></div>","PeriodicalId":51006,"journal":{"name":"Current Problems in Cardiology","volume":"50 10","pages":"Article 103148"},"PeriodicalIF":3.3,"publicationDate":"2025-08-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144812628","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Electrodes and leads in electrocardiography: a conceptual review 心电图中的电极与导联:概念回顾。
IF 3.3 3区 医学
Current Problems in Cardiology Pub Date : 2025-08-06 DOI: 10.1016/j.cpcardiol.2025.103150
Mario J. Mc Loughlin MD , Pedro Brugada MD
{"title":"Electrodes and leads in electrocardiography: a conceptual review","authors":"Mario J. Mc Loughlin MD ,&nbsp;Pedro Brugada MD","doi":"10.1016/j.cpcardiol.2025.103150","DOIUrl":"10.1016/j.cpcardiol.2025.103150","url":null,"abstract":"","PeriodicalId":51006,"journal":{"name":"Current Problems in Cardiology","volume":"50 10","pages":"Article 103150"},"PeriodicalIF":3.3,"publicationDate":"2025-08-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144805252","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Amiodarone: Get in rhythm or get off the dance floor. Analyzing the overuse of long term amiodarone in patients with atrial fibrillation 胺碘酮:要么跟上节奏,要么离开舞池。分析长期胺碘酮在房颤患者中的过度使用。
IF 3.3 3区 医学
Current Problems in Cardiology Pub Date : 2025-08-05 DOI: 10.1016/j.cpcardiol.2025.103145
Lincoln Smith DO , Jayden Navarro DO , Mikayla Kidd DO , Jacob Keesee DO , Shashi Nagabandi MD , Rami N. Khouzam MD, FACC, FACP, FASCNC, FSSCI, FASE, FSCAI
{"title":"Amiodarone: Get in rhythm or get off the dance floor. Analyzing the overuse of long term amiodarone in patients with atrial fibrillation","authors":"Lincoln Smith DO ,&nbsp;Jayden Navarro DO ,&nbsp;Mikayla Kidd DO ,&nbsp;Jacob Keesee DO ,&nbsp;Shashi Nagabandi MD ,&nbsp;Rami N. Khouzam MD, FACC, FACP, FASCNC, FSSCI, FASE, FSCAI","doi":"10.1016/j.cpcardiol.2025.103145","DOIUrl":"10.1016/j.cpcardiol.2025.103145","url":null,"abstract":"","PeriodicalId":51006,"journal":{"name":"Current Problems in Cardiology","volume":"50 10","pages":"Article 103145"},"PeriodicalIF":3.3,"publicationDate":"2025-08-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144796048","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Metabolic syndrome, ischemic heart disease, and heart failure: insights from the Colombian Heart Failure Registry (RECOLFACA) 代谢综合征、缺血性心脏病和心力衰竭:来自哥伦比亚心力衰竭登记(RECOLFACA)的见解。
IF 3.3 3区 医学
Current Problems in Cardiology Pub Date : 2025-08-05 DOI: 10.1016/j.cpcardiol.2025.103146
Miguel Álvarez Mejía MD , Sofía López Cárdenas MD , Luis Eduardo Echeverría MD , Alex Rivera-Toquica MD , Juan Esteban Gómez Mesa MD , Clara Inés Saldarriaga Gutiérrez MD , Juan Fernando Carvajal Estupiñán MD , Claudia Victoria Anchique Santos MD , Jannes Buelvas Herazo MD , Paula Luna MD , Ángel Alberto García Peña MDPhD
{"title":"Metabolic syndrome, ischemic heart disease, and heart failure: insights from the Colombian Heart Failure Registry (RECOLFACA)","authors":"Miguel Álvarez Mejía MD ,&nbsp;Sofía López Cárdenas MD ,&nbsp;Luis Eduardo Echeverría MD ,&nbsp;Alex Rivera-Toquica MD ,&nbsp;Juan Esteban Gómez Mesa MD ,&nbsp;Clara Inés Saldarriaga Gutiérrez MD ,&nbsp;Juan Fernando Carvajal Estupiñán MD ,&nbsp;Claudia Victoria Anchique Santos MD ,&nbsp;Jannes Buelvas Herazo MD ,&nbsp;Paula Luna MD ,&nbsp;Ángel Alberto García Peña MDPhD","doi":"10.1016/j.cpcardiol.2025.103146","DOIUrl":"10.1016/j.cpcardiol.2025.103146","url":null,"abstract":"<div><h3>Background</h3><div>Ischemic heart disease (IHD) is still a leading cause of morbidity and mortality worldwide, with major implications for healthcare systems, especially in low- and middle-income countries. Effective metabolic control and risk factor management, including evidence-based pharmacological therapies such as statins, ACE inhibitors (ACEIs), and angiotensin receptor-neprilysin inhibitors (ARNIs), are essential for reducing adverse outcomes. However, gaps persist in the implementation of these therapies, particularly in resource-limited regions.</div></div><div><h3>Objective</h3><div>To evaluate metabolic control and the use of evidence-based therapies in patients with IHD enrolled in the Colombian Heart Failure Registry (RECOLFACA), and to identify barriers to optimal treatment implementation.</div></div><div><h3>Methods</h3><div>This cross-sectional study analyzed demographic, clinical, and biochemical data, as well as medication usage, from patients with confirmed IHD. Descriptive and inferential statistical analyses were performed to identify treatment patterns and associated factors.</div></div><div><h3>Results</h3><div>Among 2,528 patients with heart failure (HF), 1,123 had IHD. Statins were prescribed to 73.6% (827), antiplatelets to 66.3% (745), and ARNIs to only 10.1% (114), despite guideline recommendations. Statin use was notably low among patients with chronic kidney disease (CKD) (18.1%), diabetes mellitus type 2 (15.8%), and both conditions combined (3.2%).</div></div><div><h3>Conclusions</h3><div>Despite robust evidence supporting their efficacy, the use of statins, ACEIs, and ARNIs remains suboptimal in Colombia. Addressing barriers to access, adherence, and healthcare delivery is crucial to improve outcomes and align clinical practices with international standards. These findings highlight the need for targeted interventions and future studies to evaluate strategies that enhance access to and adherence with guideline-directed therapies.</div></div>","PeriodicalId":51006,"journal":{"name":"Current Problems in Cardiology","volume":"50 10","pages":"Article 103146"},"PeriodicalIF":3.3,"publicationDate":"2025-08-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144796052","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Expanding the concept of pharma-cise: A graphical primer for clinicians, researchers and industry 扩展制药概念:临床医生,研究人员和行业的图形入门。
IF 3.3 3区 医学
Current Problems in Cardiology Pub Date : 2025-08-05 DOI: 10.1016/j.cpcardiol.2025.103144
Ross Arena PhD , Jonathan Myers PhD , Nicolaas P. Pronk PhD
{"title":"Expanding the concept of pharma-cise: A graphical primer for clinicians, researchers and industry","authors":"Ross Arena PhD ,&nbsp;Jonathan Myers PhD ,&nbsp;Nicolaas P. Pronk PhD","doi":"10.1016/j.cpcardiol.2025.103144","DOIUrl":"10.1016/j.cpcardiol.2025.103144","url":null,"abstract":"<div><div>A human’s ability to transfer oxygen from the environment to skeletal muscle and conversely remove carbon dioxide from skeletal muscle back to the environment during physical exertion is a critical representation of healthy longevity and functional capacity. Cardiorespiratory fitness (CRF) is the accepted construct for the assessment of oxygen consumption (VO<sub>2</sub>) and carbon dioxide production (VCO<sub>2</sub>) – CRF is most accurately quantified through cardiopulmonary exercise testing (CPET) in the clinical setting. All pharmacological interventions, from experimental to approved and on the market, are meant to impact one or more human physiological processes. In this context, the graphical primer on the physiological process of VO<sub>2</sub> and VCO<sub>2</sub> presented herein should facilitate the thought process on how pharmacology interacts with the factors that influence the capacity for physical exertion. Exercise is medicine and CRF is a vital sign and as such, the former should be prescribed to all capable individuals, and the latter should be considered a primary efficacy outcome measure in clinical and research settings. There is an opportunity to synergize and further enhance patient outcomes when pharmacologic and exercise interventions are considered integrated and in combination– a concept recently defined as pharma-cise – the graphical primer is proposed to facilitate application of this concept.</div></div>","PeriodicalId":51006,"journal":{"name":"Current Problems in Cardiology","volume":"50 10","pages":"Article 103144"},"PeriodicalIF":3.3,"publicationDate":"2025-08-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144796050","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Corrigendum to “Clinical outcomes and mortality in patients with atrial fibrillation and recently diagnosed lung cancer in oncology outpatient settings” [Current Problems in Cardiology 49(2024) 102239] “肿瘤门诊房颤和新近诊断的肺癌患者的临床结果和死亡率”的勘误表[心脏病学当前问题49(2024)102239]。
IF 3.3 3区 医学
Current Problems in Cardiology Pub Date : 2025-08-05 DOI: 10.1016/j.cpcardiol.2025.103132
Alberto Piserra López-Fernández De Heredia , Martín Ruiz Ortiz , Alejandro I Pérez Cabeza , Arancha Díaz Expósito , María I Fernández Valenzuela , Magdalena Carrillo Bailén , Inara Alarcón De La Lastra Cubiles , Alberto Moreno Vega , Manuel Zalabardo Aguilar , Marinela Chaparro Muñoz , Teresa García Manrique , Javier Torres Llergo , Ana Laura Ortega Granados , José J Sánchez Fernández , Julio Calvete Cadenas , Dolores Mesa Rubio , Working Groups of Atrial Fibrillation and Cardio-Onco-Hematology of the Andalusian Society of Cardiology
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