Current Problems in Cardiology最新文献

{"title":"Revisiting type 2 myocardial infarction: Unmet clinical needs","authors":"Andrea Palermi ,&nbsp;Silvio Saraullo ,&nbsp;Maria Bernadette Giordano ,&nbsp;Fabrizio Ricci ,&nbsp;Sabina Gallina ,&nbsp;Giulia Renda","doi":"10.1016/j.cpcardiol.2025.103148","DOIUrl":"10.1016/j.cpcardiol.2025.103148","url":null,"abstract":"<div><div>Cardiovascular disease is the most common cause of mortality and morbidity worldwide and acute coronary syndrome (ACS) is often the first clinical manifestation. Currently, the diagnosis of acute myocardial infarction (AMI) is based on the fourth universal definition of myocardial infarction (MI), with different subtypes based on their pathophysiological background. While type 1 myocardial infarction (T1MI) is defined by an acute coronary event with plaque disruption and consequent athero-thrombosis, type 2 myocardial infarction (T2MI) is defined as an event due to oxygen demand and supply imbalance, unrelated to acute coronary athero-thrombosis. The differentiation between these two entities is crucial since T1MI benefits from an early invasive approach aimed at myocardial reperfusion, while in T2MI it is critical to focus on the cause of the ischemia mismatch. Furthermore, T2MI is often associated with a poorer prognosis. The presence and severity of coronary artery disease (CAD) may significantly influence the ischemic threshold and the risk of T2MI, as it has been identified as an independent predictor of cardiovascular death and recurrent MI. The key point of contention is determining the presence of CAD in T2MI to identify patients eligible for a reperfusion strategy and to tailor therapy as well as secondary prevention strategies.</div><div>In this narrative review, we aim to highlight the differences in clinical features, imaging, and biomarkers between T1MI and T2MI, emphasizing the role of CAD, in refining the diagnostic-therapeutic algorithm in T2MI.</div></div>","PeriodicalId":51006,"journal":{"name":"Current Problems in Cardiology","volume":"50 10","pages":"Article 103148"},"PeriodicalIF":3.3,"publicationDate":"2025-08-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144812628","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Electrodes and leads in electrocardiography: a conceptual review","authors":"Mario J. Mc Loughlin MD ,&nbsp;Pedro Brugada MD","doi":"10.1016/j.cpcardiol.2025.103150","DOIUrl":"10.1016/j.cpcardiol.2025.103150","url":null,"abstract":"","PeriodicalId":51006,"journal":{"name":"Current Problems in Cardiology","volume":"50 10","pages":"Article 103150"},"PeriodicalIF":3.3,"publicationDate":"2025-08-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144805252","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Amiodarone: Get in rhythm or get off the dance floor. Analyzing the overuse of long term amiodarone in patients with atrial fibrillation","authors":"Lincoln Smith DO ,&nbsp;Jayden Navarro DO ,&nbsp;Mikayla Kidd DO ,&nbsp;Jacob Keesee DO ,&nbsp;Shashi Nagabandi MD ,&nbsp;Rami N. Khouzam MD, FACC, FACP, FASCNC, FSSCI, FASE, FSCAI","doi":"10.1016/j.cpcardiol.2025.103145","DOIUrl":"10.1016/j.cpcardiol.2025.103145","url":null,"abstract":"","PeriodicalId":51006,"journal":{"name":"Current Problems in Cardiology","volume":"50 10","pages":"Article 103145"},"PeriodicalIF":3.3,"publicationDate":"2025-08-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144796048","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Metabolic syndrome, ischemic heart disease, and heart failure: insights from the Colombian Heart Failure Registry (RECOLFACA)","authors":"Miguel Álvarez Mejía MD ,&nbsp;Sofía López Cárdenas MD ,&nbsp;Luis Eduardo Echeverría MD ,&nbsp;Alex Rivera-Toquica MD ,&nbsp;Juan Esteban Gómez Mesa MD ,&nbsp;Clara Inés Saldarriaga Gutiérrez MD ,&nbsp;Juan Fernando Carvajal Estupiñán MD ,&nbsp;Claudia Victoria Anchique Santos MD ,&nbsp;Jannes Buelvas Herazo MD ,&nbsp;Paula Luna MD ,&nbsp;Ángel Alberto García Peña MDPhD","doi":"10.1016/j.cpcardiol.2025.103146","DOIUrl":"10.1016/j.cpcardiol.2025.103146","url":null,"abstract":"<div><h3>Background</h3><div>Ischemic heart disease (IHD) is still a leading cause of morbidity and mortality worldwide, with major implications for healthcare systems, especially in low- and middle-income countries. Effective metabolic control and risk factor management, including evidence-based pharmacological therapies such as statins, ACE inhibitors (ACEIs), and angiotensin receptor-neprilysin inhibitors (ARNIs), are essential for reducing adverse outcomes. However, gaps persist in the implementation of these therapies, particularly in resource-limited regions.</div></div><div><h3>Objective</h3><div>To evaluate metabolic control and the use of evidence-based therapies in patients with IHD enrolled in the Colombian Heart Failure Registry (RECOLFACA), and to identify barriers to optimal treatment implementation.</div></div><div><h3>Methods</h3><div>This cross-sectional study analyzed demographic, clinical, and biochemical data, as well as medication usage, from patients with confirmed IHD. Descriptive and inferential statistical analyses were performed to identify treatment patterns and associated factors.</div></div><div><h3>Results</h3><div>Among 2,528 patients with heart failure (HF), 1,123 had IHD. Statins were prescribed to 73.6% (827), antiplatelets to 66.3% (745), and ARNIs to only 10.1% (114), despite guideline recommendations. Statin use was notably low among patients with chronic kidney disease (CKD) (18.1%), diabetes mellitus type 2 (15.8%), and both conditions combined (3.2%).</div></div><div><h3>Conclusions</h3><div>Despite robust evidence supporting their efficacy, the use of statins, ACEIs, and ARNIs remains suboptimal in Colombia. Addressing barriers to access, adherence, and healthcare delivery is crucial to improve outcomes and align clinical practices with international standards. These findings highlight the need for targeted interventions and future studies to evaluate strategies that enhance access to and adherence with guideline-directed therapies.</div></div>","PeriodicalId":51006,"journal":{"name":"Current Problems in Cardiology","volume":"50 10","pages":"Article 103146"},"PeriodicalIF":3.3,"publicationDate":"2025-08-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144796052","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Expanding the concept of pharma-cise: A graphical primer for clinicians, researchers and industry","authors":"Ross Arena PhD ,&nbsp;Jonathan Myers PhD ,&nbsp;Nicolaas P. Pronk PhD","doi":"10.1016/j.cpcardiol.2025.103144","DOIUrl":"10.1016/j.cpcardiol.2025.103144","url":null,"abstract":"<div><div>A human’s ability to transfer oxygen from the environment to skeletal muscle and conversely remove carbon dioxide from skeletal muscle back to the environment during physical exertion is a critical representation of healthy longevity and functional capacity. Cardiorespiratory fitness (CRF) is the accepted construct for the assessment of oxygen consumption (VO₂) and carbon dioxide production (VCO₂) – CRF is most accurately quantified through cardiopulmonary exercise testing (CPET) in the clinical setting. All pharmacological interventions, from experimental to approved and on the market, are meant to impact one or more human physiological processes. In this context, the graphical primer on the physiological process of VO₂ and VCO₂ presented herein should facilitate the thought process on how pharmacology interacts with the factors that influence the capacity for physical exertion. Exercise is medicine and CRF is a vital sign and as such, the former should be prescribed to all capable individuals, and the latter should be considered a primary efficacy outcome measure in clinical and research settings. There is an opportunity to synergize and further enhance patient outcomes when pharmacologic and exercise interventions are considered integrated and in combination– a concept recently defined as pharma-cise – the graphical primer is proposed to facilitate application of this concept.</div></div>","PeriodicalId":51006,"journal":{"name":"Current Problems in Cardiology","volume":"50 10","pages":"Article 103144"},"PeriodicalIF":3.3,"publicationDate":"2025-08-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144796050","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Corrigendum to “Clinical outcomes and mortality in patients with atrial fibrillation and recently diagnosed lung cancer in oncology outpatient settings” [Current Problems in Cardiology 49(2024) 102239]","authors":"Alberto Piserra López-Fernández De Heredia ,&nbsp;Martín Ruiz Ortiz ,&nbsp;Alejandro I Pérez Cabeza ,&nbsp;Arancha Díaz Expósito ,&nbsp;María I Fernández Valenzuela ,&nbsp;Magdalena Carrillo Bailén ,&nbsp;Inara Alarcón De La Lastra Cubiles ,&nbsp;Alberto Moreno Vega ,&nbsp;Manuel Zalabardo Aguilar ,&nbsp;Marinela Chaparro Muñoz ,&nbsp;Teresa García Manrique ,&nbsp;Javier Torres Llergo ,&nbsp;Ana Laura Ortega Granados ,&nbsp;José J Sánchez Fernández ,&nbsp;Julio Calvete Cadenas ,&nbsp;Dolores Mesa Rubio ,&nbsp;Working Groups of Atrial Fibrillation and Cardio-Onco-Hematology of the Andalusian Society of Cardiology","doi":"10.1016/j.cpcardiol.2025.103132","DOIUrl":"10.1016/j.cpcardiol.2025.103132","url":null,"abstract":"","PeriodicalId":51006,"journal":{"name":"Current Problems in Cardiology","volume":"50 11","pages":"Article 103132"},"PeriodicalIF":3.3,"publicationDate":"2025-08-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144790658","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Corrigendum to “Clinical profile and cardiovascular events in patients with atrial fibrillation and hematologic malignancies with recent initiation of targeted therapy: real-life data from CANAC-FA registry” [Current Problems in Cardiology 50(2025):102974]","authors":"Alberto Piserra López Fernández de Heredia ,&nbsp;Martín Ruiz Ortiz ,&nbsp;Javier Torres Llergo ,&nbsp;Magdalena Carrillo Bailen ,&nbsp;María Sánchez de Castro ,&nbsp;Margarita Fernández de la Mata ,&nbsp;Arancha Díaz Exposito ,&nbsp;Alejandro I Pérez Cabeza ,&nbsp;Mónica Delgado Ortega ,&nbsp;María García Fortes ,&nbsp;Inmaculada Fernández Valenzuela ,&nbsp;Marinela Chaparro Muñoz ,&nbsp;Alicia Rodríguez Fernández ,&nbsp;Ana María Rodríguez Almodóvar ,&nbsp;Inara Alarcón de la Lastra Cubiles ,&nbsp;Fátima Esteban Martínez ,&nbsp;Francisco Javier Capote Huelva ,&nbsp;José Javier Sánchez Fernandez ,&nbsp;Dolores Mesa Rubio ,&nbsp;Working Groups of Atrial Fibrillation and Cardio-Onco-Hematology of the Andalusian Society of Cardiology","doi":"10.1016/j.cpcardiol.2025.103131","DOIUrl":"10.1016/j.cpcardiol.2025.103131","url":null,"abstract":"","PeriodicalId":51006,"journal":{"name":"Current Problems in Cardiology","volume":"50 11","pages":"Article 103131"},"PeriodicalIF":3.3,"publicationDate":"2025-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144765780","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Corrigendum to “New severity criteria for tricuspid regurgitation in a broad population of “real life” patients: prevalence and prognostic impact” [Current Problems in Cardiology 49(2024) 102211]","authors":"Ana Fernández Ruiz ,&nbsp;Martín Ruiz Ortiz ,&nbsp;Consuelo Fernández-Avilés Irache ,&nbsp;Ana María Rodríguez Almodóvar ,&nbsp;Mónica Delgado Ortega ,&nbsp;Fátima Esteban Martínez ,&nbsp;Adriana Resúa Collazo ,&nbsp;Gloria Heredia Campos ,&nbsp;Manuel Pan Álvarez-Ossorio ,&nbsp;Dolores Mesa Rubio","doi":"10.1016/j.cpcardiol.2025.103130","DOIUrl":"10.1016/j.cpcardiol.2025.103130","url":null,"abstract":"","PeriodicalId":51006,"journal":{"name":"Current Problems in Cardiology","volume":"50 10","pages":"Article 103130"},"PeriodicalIF":3.3,"publicationDate":"2025-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144765781","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Editor’s Message","authors":"","doi":"10.1016/S0146-2806(25)00161-6","DOIUrl":"10.1016/S0146-2806(25)00161-6","url":null,"abstract":"","PeriodicalId":51006,"journal":{"name":"Current Problems in Cardiology","volume":"50 9","pages":"Article 103141"},"PeriodicalIF":3.0,"publicationDate":"2025-07-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144714066","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Title Page","authors":"","doi":"10.1016/S0146-2806(25)00155-0","DOIUrl":"10.1016/S0146-2806(25)00155-0","url":null,"abstract":"","PeriodicalId":51006,"journal":{"name":"Current Problems in Cardiology","volume":"50 9","pages":"Article 103135"},"PeriodicalIF":3.0,"publicationDate":"2025-07-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144714065","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}