Advances in Virus Research最新文献_第3页

The New Zealand perspective of an ecosystem biology response to grapevine leafroll disease. 新西兰从生态系统生物学角度应对葡萄落叶病。

2区医学

Advances in Virus Research Pub Date : 2024-01-01 Epub Date: 2024-02-29 DOI: 10.1016/bs.aivir.2024.02.001

Kar Mun Chooi, Vaughn A Bell, Arnaud G Blouin, Manoharie Sandanayaka, Rebecca Gough, Asha Chhagan, Robin M MacDiarmid

{"title":"The New Zealand perspective of an ecosystem biology response to grapevine leafroll disease.","authors":"Kar Mun Chooi, Vaughn A Bell, Arnaud G Blouin, Manoharie Sandanayaka, Rebecca Gough, Asha Chhagan, Robin M MacDiarmid","doi":"10.1016/bs.aivir.2024.02.001","DOIUrl":"10.1016/bs.aivir.2024.02.001","url":null,"abstract":"Grapevine leafroll-associated virus 3 (GLRaV-3) is a major pathogen of grapevines worldwide resulting in grapevine leafroll disease (GLD), reduced fruit yield, berry quality and vineyard profitability. Being graft transmissible, GLRaV-3 is also transmitted between grapevines by multiple hemipteran insects (mealybugs and soft scale insects). Over the past 20 years, New Zealand has developed and utilized integrated pest management (IPM) solutions that have slowly transitioned to an ecosystem-based biological response to GLD. These IPM solutions and combinations are based on a wealth of research within the temperate climates of New Zealand's nation-wide grape production. To provide context, the grapevine viruses present in the national vineyard estate and how these have been identified are described; the most pathogenic and destructive of these is GLRaV-3. We provide an overview of research on GLRaV-3 genotypes and biology within grapevines and describe the progressive development of GLRaV-3/GLD diagnostics based on molecular, serological, visual, and sensor-based technologies. Research on the ecology and control of the mealybugs Pseudococcus calceolariae and P. longispinus, the main insect vectors of GLRaV-3 in New Zealand, is described together with the implications of mealybug biological control agents and prospects to enhance their abundance and/or fitness in the vineyard. Virus transmission by mealybugs is described, with emphasis on understanding the interactions between GLRaV-3, vectors, and plants (grapevines, alternative hosts, or non-hosts of the virus). Disease management through grapevine removal and the economic influence of different removal strategies is detailed. Overall, the review summarizes research by an interdisciplinary team working in close association with the national industry body, New Zealand Winegrowers. Teamwork and communication across the whole industry has enabled implementation of research for the management of GLD.","PeriodicalId":50977,"journal":{"name":"Advances in Virus Research","volume":"118 ","pages":"213-272"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140068952","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Human norovirus cultivation models, immune response and vaccine landscape. 人类诺如病毒培养模型、免疫反应和疫苗前景。

2区医学

Advances in Virus Research Pub Date : 2024-01-01 Epub Date: 2024-09-24 DOI: 10.1016/bs.aivir.2024.09.001

Thomas D Burton, Julio Carrera Montoya, Thalia Frota, Jason M Mackenzie

引用次数: 0

Usutu virus, an emerging arbovirus with One Health importance. 乌苏图病毒，一种对 "一个健康 "具有重要意义的新出现的虫媒病毒。

2区医学

Advances in Virus Research Pub Date : 2024-01-01 Epub Date: 2024-09-27 DOI: 10.1016/bs.aivir.2024.09.002

Sarah C Kuchinsky, Nisha K Duggal

{"title":"Usutu virus, an emerging arbovirus with One Health importance.","authors":"Sarah C Kuchinsky, Nisha K Duggal","doi":"10.1016/bs.aivir.2024.09.002","DOIUrl":"10.1016/bs.aivir.2024.09.002","url":null,"abstract":"Usutu virus (USUV, Flaviviridae) is an emerging arbovirus that has led to epizootic outbreaks in birds and numerous human neuroinvasive disease cases in Europe. It is maintained in an enzootic cycle with Culex mosquitoes and passerine birds, a transmission cycle that is shared by West Nile virus (WNV) and St. Louis encephalitis virus (SLEV), two flaviviruses that are endemic in the United States. USUV and WNV co-circulate in Africa and Europe, and SLEV and WNV co-circulate in North America. These three viruses are prime examples of One Health issues, in which the interactions between humans, animals, and the environments they reside in can have important health impacts. The three facets of One Health are interwoven throughout this article as we discuss the mechanisms of flavivirus transmission and emergence. We explore the possibility of USUV emergence in the United States by analyzing the shared characteristics among USUV, WNV, and SLEV, including the role that flavivirus co-infections and sequential exposures may play in viral emergence. Finally, we provide insights on the importance of integrated surveillance programs as One Health tools that can be used to mitigate USUV emergence and spread.","PeriodicalId":50977,"journal":{"name":"Advances in Virus Research","volume":"120 ","pages":"39-75"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142512396","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

CMV-encoded GPCRs in infection, disease, and pathogenesis. CMV 编码的 GPCR 在感染、疾病和发病机制中的作用。

2区医学

Advances in Virus Research Pub Date : 2024-01-01 Epub Date: 2024-02-21 DOI: 10.1016/bs.aivir.2024.01.001

William E Miller, Christine M O'Connor

引用次数: 0

Selection of nonstandard viral genomes during the evolution of RNA viruses: A virus survival strategy or a pesky inconvenience? RNA 病毒进化过程中对非标准病毒基因组的选择：病毒的生存策略还是令人讨厌的不便？

2区医学

Advances in Virus Research Pub Date : 2024-01-01 Epub Date: 2024-06-08 DOI: 10.1016/bs.aivir.2024.05.002

Lavinia J González Aparicio, Carolina B López

引用次数: 0

Ubiquitination in viral entry and replication: Mechanisms and implications. 病毒进入和复制过程中的泛素化：机制和影响。

2区医学

Advances in Virus Research Pub Date : 2024-01-01 Epub Date: 2024-06-08 DOI: 10.1016/bs.aivir.2024.05.001

Maria Velez-Brochero, Padmanava Behera, Kazi Sabrina Afreen, Abby Odle, Ricardo Rajsbaum

引用次数: 0

Critical points for the design and application of RNA silencing constructs for plant virus resistance. 植物抗病毒RNA沉默构建物设计与应用的关键点。

2区医学

Advances in Virus Research Pub Date : 2023-01-01 DOI: 10.1016/bs.aivir.2023.02.001

Masoud Akbarimotlagh, Abdolbaset Azizi, Masoud Shams-Bakhsh, Majid Jafari, Aysan Ghasemzadeh, Peter Palukaitis

{"title":"Critical points for the design and application of RNA silencing constructs for plant virus resistance.","authors":"Masoud Akbarimotlagh, Abdolbaset Azizi, Masoud Shams-Bakhsh, Majid Jafari, Aysan Ghasemzadeh, Peter Palukaitis","doi":"10.1016/bs.aivir.2023.02.001","DOIUrl":"https://doi.org/10.1016/bs.aivir.2023.02.001","url":null,"abstract":"Control of plant virus diseases is a big challenge in agriculture as is resistance in plant lines to infection by viruses. Recent progress using advanced technologies has provided fast and durable alternatives. One of the most promising techniques against plant viruses that is cost-effective and environmentally safe is RNA silencing or RNA interference (RNAi), a technology that could be used alone or along with other control methods. To achieve the goals of fast and durable resistance, the expressed and target RNAs have been examined in many studies, with regard to the variability in silencing efficiency, which is regulated by various factors such as target sequences, target accessibility, RNA secondary structures, sequence variation in matching positions, and other intrinsic characteristics of various small RNAs. Developing a comprehensive and applicable toolbox for the prediction and construction of RNAi helps researchers to achieve the acceptable performance level of silencing elements. Although the attainment of complete prediction of RNAi robustness is not possible, as it also depends on the cellular genetic background and the nature of the target sequences, some important critical points have been discerned. Thus, the efficiency and robustness of RNA silencing against viruses can be improved by considering the various parameters of the target sequence and the construct design. In this review, we provide a comprehensive treatise regarding past, present and future prospective developments toward designing and applying RNAi constructs for resistance to plant viruses.","PeriodicalId":50977,"journal":{"name":"Advances in Virus Research","volume":"115 ","pages":"159-203"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9513331","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

How do they do it? The infection biology of potyviruses. 他们是怎么做到的？potyviruses的感染生物学。

2区医学

Advances in Virus Research Pub Date : 2023-01-01 Epub Date: 2023-09-15 DOI: 10.1016/bs.aivir.2023.07.001

Kristiina Mäkinen, William Aspelin, Maija Pollari, Linping Wang

引用次数: 0

Entry and egress of human astroviruses. 人类星形病毒的进出。

2区医学

Advances in Virus Research Pub Date : 2023-01-01 Epub Date: 2023-09-07 DOI: 10.1016/bs.aivir.2023.08.001

Pedro Soares Porto, Andres Rivera, Rootjikarn Moonrinta, Christiane E Wobus

{"title":"Entry and egress of human astroviruses.","authors":"Pedro Soares Porto, Andres Rivera, Rootjikarn Moonrinta, Christiane E Wobus","doi":"10.1016/bs.aivir.2023.08.001","DOIUrl":"10.1016/bs.aivir.2023.08.001","url":null,"abstract":"Astroviruses encapsidate a positive-sense, single-stranded RNA genome into ∼30nm icosahedral particles that infect a wide range of mammalian and avian species, but their biology is not well understood. Human astroviruses (HAstV) are divided into three clades: classical HAstV serotypes 1-8, and novel or non-classical HAstV of the MLB and VA clades. These viruses are part of two genogroups and phylogenetically cluster with other mammalian astroviruses, highlighting their zoonotic potential. HAstV are a highly prevalent cause of nonbacterial gastroenteritis, primarily in children, the elderly and immunocompromised. Additionally, asymptomatic infections and extraintestinal disease (e.g., encephalitis), are also observed, mostly in immunocompetent or immunocompromised individuals, respectively. While these viruses are highly prevalent, no approved vaccines or antivirals are available to prevent or treat infections. This is in large part due to their understudied nature and the limited understanding of even very basic features of their life cycle and pathogenesis at the cellular and organismal level. This review will summarize molecular features of human astrovirus biology, pathogenesis, and tropism, and then focus on two stages of the viral life cycle, namely entry and egress, since these are proven targets for therapeutic interventions. We will further highlight gaps in knowledge in hopes of stimulating future research into these understudied viruses.","PeriodicalId":50977,"journal":{"name":"Advances in Virus Research","volume":"117 ","pages":"81-119"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41219528","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Novel insights into virus-host interactions using the model organism C. elegans. 利用模式生物 C. elegans 对病毒-宿主相互作用的新见解。

2区医学

Advances in Virus Research Pub Date : 2023-01-01 Epub Date: 2023-04-03 DOI: 10.1016/bs.aivir.2023.03.001

Chika Fujii, David Wang

{"title":"Novel insights into virus-host interactions using the model organism C. elegans.","authors":"Chika Fujii, David Wang","doi":"10.1016/bs.aivir.2023.03.001","DOIUrl":"10.1016/bs.aivir.2023.03.001","url":null,"abstract":"Viruses continue to pose a public health threat raising the need for effective management strategies. Currently existing antiviral therapeutics are often specific to only a single viral species, and resistance to the therapeutic can often arise, and therefore new therapeutics are needed. The C. elegans-Orsay virus system offers a powerful platform for studying RNA virus-host interactions that could ultimately lead to novel targets for antiviral therapy. The relative simplicity of C. elegans, the well-established experimental tools, and its extensive evolutionary conservation of genes and pathways with mammals are key features of this model. Orsay virus, a bisegmented positive sense RNA virus, is a natural pathogen of C. elegans. Orsay virus infection can be studied in a multicellular organismal context, overcoming some of the limitations inherent to tissue culture-based systems. Moreover, compared to mice, the rapid generation time of C. elegans enables robust and facile forward genetics. This review aims to summarize studies that have laid the foundation for the C. elegans-Orsay virus experimental system, experimental tools, and key examples of C. elegans host factors that impact Orsay virus infection that have evolutionarily conserved function in mammalian virus infection.","PeriodicalId":50977,"journal":{"name":"Advances in Virus Research","volume":"115 ","pages":"135-158"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9460225","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0