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Advances in Virus Research最新文献

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Reverse genetic systems: Rational design of coronavirus live attenuated vaccines with immune sequelae. 反向遗传系统:冠状病毒减毒活疫苗免疫后遗症的合理设计。
2区 医学
Advances in Virus Research Pub Date : 2020-01-01 Epub Date: 2020-06-30 DOI: 10.1016/bs.aivir.2020.06.003
Zhiqian Ma, Zhiwei Li, Linfang Dong, Ting Yang, Shuqi Xiao
{"title":"Reverse genetic systems: Rational design of coronavirus live attenuated vaccines with immune sequelae.","authors":"Zhiqian Ma,&nbsp;Zhiwei Li,&nbsp;Linfang Dong,&nbsp;Ting Yang,&nbsp;Shuqi Xiao","doi":"10.1016/bs.aivir.2020.06.003","DOIUrl":"https://doi.org/10.1016/bs.aivir.2020.06.003","url":null,"abstract":"<p><p>Since the end of 2019, the global COVID-19 outbreak has once again made coronaviruses a hot topic. Vaccines are hoped to be an effective way to stop the spread of the virus. However, there are no clinically approved vaccines available for coronavirus infections. Reverse genetics technology can realize the operation of RNA virus genomes at the DNA level and provide new ideas and strategies for the development of new vaccines. In this review, we systematically describe the role of reverse genetics technology in studying the effects of coronavirus proteins on viral virulence and innate immunity, cell and tissue tropism and antiviral drug screening. An efficient reverse genetics platform is useful for obtaining the ideal attenuated strain to prepare an attenuated live vaccine.</p>","PeriodicalId":50977,"journal":{"name":"Advances in Virus Research","volume":"107 ","pages":"383-416"},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/bs.aivir.2020.06.003","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38191545","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 11
Preface 前言
2区 医学
Advances in Virus Research Pub Date : 2019-09-12 DOI: 10.1016/S0065-3527(19)30051-X
Félix A. Rey
{"title":"Preface","authors":"Félix A. Rey","doi":"10.1016/S0065-3527(19)30051-X","DOIUrl":"https://doi.org/10.1016/S0065-3527(19)30051-X","url":null,"abstract":"","PeriodicalId":50977,"journal":{"name":"Advances in Virus Research","volume":"105 1","pages":"xi - xiii"},"PeriodicalIF":0.0,"publicationDate":"2019-09-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0065-3527(19)30051-X","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48563559","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Structural insights into coronavirus entry 冠状病毒进入的结构洞察
2区 医学
Advances in Virus Research Pub Date : 2019-08-22 DOI: 10.1016/bs.aivir.2019.08.002
A. Tortoricia, David Veeslera
{"title":"Structural insights into coronavirus entry","authors":"A. Tortoricia, David Veeslera","doi":"10.1016/bs.aivir.2019.08.002","DOIUrl":"https://doi.org/10.1016/bs.aivir.2019.08.002","url":null,"abstract":"","PeriodicalId":50977,"journal":{"name":"Advances in Virus Research","volume":"105 1","pages":"93 - 116"},"PeriodicalIF":0.0,"publicationDate":"2019-08-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/bs.aivir.2019.08.002","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46508295","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 614
Entry of bunyaviruses into plants and vectors. 布尼亚病毒进入植物和媒介。
2区 医学
Advances in Virus Research Pub Date : 2019-01-01 DOI: 10.1016/bs.aivir.2019.07.001
Yuting Chen, M. Dessau, D. Rotenberg, David A. Rasmussen, A. Whitfield
{"title":"Entry of bunyaviruses into plants and vectors.","authors":"Yuting Chen, M. Dessau, D. Rotenberg, David A. Rasmussen, A. Whitfield","doi":"10.1016/bs.aivir.2019.07.001","DOIUrl":"https://doi.org/10.1016/bs.aivir.2019.07.001","url":null,"abstract":"","PeriodicalId":50977,"journal":{"name":"Advances in Virus Research","volume":"474 1","pages":"65-96"},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/bs.aivir.2019.07.001","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"54045215","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 17
Hantavirus entry: Perspectives and recent advances. 汉坦病毒进入:观点和最新进展。
2区 医学
Advances in Virus Research Pub Date : 2019-01-01 DOI: 10.1016/BS.AIVIR.2019.07.002
E. Mittler, M. Dieterle, L. Kleinfelter, Megan M. Slough, K. Chandran, R. Jangra
{"title":"Hantavirus entry: Perspectives and recent advances.","authors":"E. Mittler, M. Dieterle, L. Kleinfelter, Megan M. Slough, K. Chandran, R. Jangra","doi":"10.1016/BS.AIVIR.2019.07.002","DOIUrl":"https://doi.org/10.1016/BS.AIVIR.2019.07.002","url":null,"abstract":"","PeriodicalId":50977,"journal":{"name":"Advances in Virus Research","volume":"104 1","pages":"185-224"},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/BS.AIVIR.2019.07.002","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"54045365","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 53
The viral replication organelles within cells studied by electron microscopy. 通过电子显微镜研究细胞内的病毒复制细胞器。
2区 医学
Advances in Virus Research Pub Date : 2019-01-01 Epub Date: 2019-08-19 DOI: 10.1016/bs.aivir.2019.07.005
Martin Sachse, Isabel Fernández de Castro, Raquel Tenorio, Cristina Risco
{"title":"The viral replication organelles within cells studied by electron microscopy.","authors":"Martin Sachse, Isabel Fernández de Castro, Raquel Tenorio, Cristina Risco","doi":"10.1016/bs.aivir.2019.07.005","DOIUrl":"10.1016/bs.aivir.2019.07.005","url":null,"abstract":"<p><p>Transmission electron microscopy (TEM) has been crucial to study viral infections. As a result of recent advances in light and electron microscopy, we are starting to be aware of the variety of structures that viruses assemble inside cells. Viruses often remodel cellular compartments to build their replication factories. Remarkably, viruses are also able to induce new membranes and new organelles. Here we revise the most relevant imaging technologies to study the biogenesis of viral replication organelles. Live cell microscopy, correlative light and electron microscopy, cryo-TEM, and three-dimensional imaging methods are unveiling how viruses manipulate cell organization. In particular, methods for molecular mapping in situ in two and three dimensions are revealing how macromolecular complexes build functional replication complexes inside infected cells. The combination of all these imaging approaches is uncovering the viral life cycle events with a detail never seen before.</p>","PeriodicalId":50977,"journal":{"name":"Advances in Virus Research","volume":"105 ","pages":"1-33"},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7112055/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10637289","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Key checkpoints in the movement of plant viruses through the host. 植物病毒通过宿主运动的关键检查点。
2区 医学
Advances in Virus Research Pub Date : 2019-01-01 DOI: 10.1016/BS.AIVIR.2019.05.001
J. Navarro, J. Sánchez-Navarro, V. Pallás
{"title":"Key checkpoints in the movement of plant viruses through the host.","authors":"J. Navarro, J. Sánchez-Navarro, V. Pallás","doi":"10.1016/BS.AIVIR.2019.05.001","DOIUrl":"https://doi.org/10.1016/BS.AIVIR.2019.05.001","url":null,"abstract":"","PeriodicalId":50977,"journal":{"name":"Advances in Virus Research","volume":"104 1","pages":"1-64"},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/BS.AIVIR.2019.05.001","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"54044691","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 44
Structural mass spectrometry goes viral. 结构质谱法走红。
2区 医学
Advances in Virus Research Pub Date : 2019-01-01 DOI: 10.1016/bs.aivir.2019.07.003
Jasmin Dülfer, A. Kádek, Janine-Denise Kopicki, Boris Krichel, C. Uetrecht
{"title":"Structural mass spectrometry goes viral.","authors":"Jasmin Dülfer, A. Kádek, Janine-Denise Kopicki, Boris Krichel, C. Uetrecht","doi":"10.1016/bs.aivir.2019.07.003","DOIUrl":"https://doi.org/10.1016/bs.aivir.2019.07.003","url":null,"abstract":"","PeriodicalId":50977,"journal":{"name":"Advances in Virus Research","volume":"105 1","pages":"189-238"},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/bs.aivir.2019.07.003","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"54045421","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 27
Contributors 贡献者
2区 医学
Advances in Virus Research Pub Date : 2019-01-01 DOI: 10.1016/s0065-3527(19)30050-8
{"title":"Contributors","authors":"","doi":"10.1016/s0065-3527(19)30050-8","DOIUrl":"https://doi.org/10.1016/s0065-3527(19)30050-8","url":null,"abstract":"","PeriodicalId":50977,"journal":{"name":"Advances in Virus Research","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/s0065-3527(19)30050-8","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"55768198","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Structural and cellular biology of rhabdovirus entry. 横纹肌病毒侵入的结构和细胞生物学。
2区 医学
Advances in Virus Research Pub Date : 2019-01-01 DOI: 10.1016/BS.AIVIR.2019.05.003
Laura Belot, A. Albertini, Y. Gaudin
{"title":"Structural and cellular biology of rhabdovirus entry.","authors":"Laura Belot, A. Albertini, Y. Gaudin","doi":"10.1016/BS.AIVIR.2019.05.003","DOIUrl":"https://doi.org/10.1016/BS.AIVIR.2019.05.003","url":null,"abstract":"","PeriodicalId":50977,"journal":{"name":"Advances in Virus Research","volume":"104 1","pages":"147-183"},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/BS.AIVIR.2019.05.003","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"54044851","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 27
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