Academic Radiology最新文献

{"title":"Growth Prediction of Ground-Glass Nodules Based on Pulmonary Vascular Morphology Nomogram","authors":"Jingyan Wu ,&nbsp;Keying Wang ,&nbsp;Lin Deng ,&nbsp;Hanzhou Tang ,&nbsp;Limin Xue ,&nbsp;Ting Yang ,&nbsp;Jinwei Qiang","doi":"10.1016/j.acra.2024.11.041","DOIUrl":"10.1016/j.acra.2024.11.041","url":null,"abstract":"<div><h3>Rationale and Objectives</h3><div>To construct a nomogram combining conventional CT features (CCTFs), morphologically abnormal tumor-related vessels (MATRVs), and clinical features to predict the two-year growth of lung ground-glass nodule (GGN).</div></div><div><h3>Methods</h3><div>High-resolution CT targeted scan images of 158 patients including 167 GGNs from January 2016 to September 2019 were retrospectively analyzed. The CCTF and MATRV of each GGN were recorded. All GGNs were randomly divided into a training set (<em>n</em> = 118) and a validation set (<em>n</em> = 49). Multiple stepwise regression was used to select the features. Multivariate logistic regression was used to construct the CCTF, CCTF-CTRV (category of tumor-related vessel), and CCTF-QTRV (quantity of tumor-related vessel) nomograms. The performance and utility of the nomograms were evaluated using the area under the receiver operating characteristic curve (AUC), net reclassification improvement (NRI), integrated discrimination improvement (IDI), and decision curve analysis (DCA).</div></div><div><h3>Results</h3><div>The AUC of the CCTF-QTRV nomogram, which included the features of smoking history, nodule pattern, lobulation, and the number of distorted and dilated vessels, was higher than the AUCs of the CCTF and CCTF-CTRV nomograms in both the training set (AUC: 0.906 vs. 0.857; vs. 0.851) and the validation set (AUC: 0.909 vs. 0.796; vs. 0.871). DCA indicated that both patients and clinicians could benefit from using the nomogram.</div></div><div><h3>Conclusion</h3><div>The nomogram constructed by combining MATRV, CCTF, and clinical information can more effectively predict the two-year growth of GGNs. This integrated approach enhances the predictive accuracy, making it a valuable tool for clinicians in managing and monitoring patients with GGNs.</div></div>","PeriodicalId":50928,"journal":{"name":"Academic Radiology","volume":"32 4","pages":"Pages 2297-2308"},"PeriodicalIF":3.8,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142792764","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evidence-Based Radiology: The Importance of Reviewers","authors":"N. Reed Dunnick MD","doi":"10.1016/j.acra.2025.02.027","DOIUrl":"10.1016/j.acra.2025.02.027","url":null,"abstract":"","PeriodicalId":50928,"journal":{"name":"Academic Radiology","volume":"32 4","pages":"Pages 1781-1782"},"PeriodicalIF":3.8,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143574574","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Diagnostic Characteristics and Clinical Relevance of Incidental Hypermetabolic Breast Lesions Detected on 18F-FDG PET-CT: A Retrospective Evaluation","authors":"Yasemin Kayadibi MD ,&nbsp;Seyfullah Halit Karagoz MD ,&nbsp;Seda Aladag Kurt MD ,&nbsp;Osman Aykan Kargin MD ,&nbsp;Cansu Guneren MD ,&nbsp;Onur Erdem Sahin MD ,&nbsp;Rauf Hamid MD ,&nbsp;Mehmet Halit Yilmaz MD","doi":"10.1016/j.acra.2024.11.031","DOIUrl":"10.1016/j.acra.2024.11.031","url":null,"abstract":"<div><h3>Rationale and Objectives</h3><div>The study aimed to evaluate demographic and radiological characteristics of breast incidentalomas found on 18-fluorodeoxyglucose Positron Emission Tomography-Computed Tomography (¹⁸F-FDG PET-CT) performed for extramammary indications.</div></div><div><h3>Materials and Methods</h3><div>A total of 12633 ¹⁸F-FDG PET-CT scans performed between January 1, 2018 and January 1, 2024, were retrospectively reviewed. Breast incidentalomas that had undergone breast imaging, tissue diagnosis, or at least 2-year radiological follow-up were included. Demographic data and lesion size were recorded. Maximum and average standardized uptake values (SUV_max-SUV_avg) and SUV corrected for lean body mass (SUL) were calculated using region of interest (ROI).</div></div><div><h3>Results</h3><div>The inclusion criteria were met in 101 lesions (81 benign and 20 malignant). The most common benign lesion was fibroadenoma (n = 21), followed by stable lesions during follow-up (n = 18) and benign breast parenchyma (n = 11). The most common malignant lesion was invasive ductal carcinoma (n = 11). The diagnostic characteristics of SUV_max≥ 3, SUL_max≥ 2, SUV_avg≥ 0.735, SUL_avg≥ 0.48, and BI-RADS≥ 4 were 75%, 70%, 75%, 70% and 100% for sensitivity, 69%, 69%, 62%, 62% and 67% for specificity, and 69.3%, 68.3%, 62.4%, 61.4% and 73.3% for accuracy, respectively. The highest negative predictive values (NPV) were obtained with BI-RADS and SUV_max (100% and 92%, respectively). No significant difference in malignancy rate was observed for the lesion size and age of the patients (<em>p</em> &gt; 0.05).</div></div><div><h3>Conclusion</h3><div>There is a risk of detecting malignancy in incidental lesions showing ¹⁸F-FDG uptake. Radiological workup must be done, but SUV_max, with a high NPV value, can be used in conjunction with BI-RADS assessment for appropriate patient selection and effective management of resources.</div></div>","PeriodicalId":50928,"journal":{"name":"Academic Radiology","volume":"32 4","pages":"Pages 1806-1815"},"PeriodicalIF":3.8,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142866045","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Generating Synthetic T2*-Weighted Gradient Echo Images of the Knee with an Open-source Deep Learning Model.","authors":"Konstantinos Vrettos, Evangelia E Vassalou, Grigoria Vamvakerou, Apostolos H Karantanas, Michail E Klontzas","doi":"10.1016/j.acra.2025.03.015","DOIUrl":"https://doi.org/10.1016/j.acra.2025.03.015","url":null,"abstract":"<p><strong>Rationale and objectives: </strong>Routine knee MRI protocols for 1.5 T and 3 T scanners, do not include T2*-w gradient echo (T2*W) images, which are useful in several clinical scenarios such as the assessment of cartilage, synovial blooming (deposition of hemosiderin), chondrocalcinosis and the evaluation of the physis in pediatric patients. Herein, we aimed to develop an open-source deep learning model that creates synthetic T2*W images of the knee using fat-suppressed intermediate-weighted images.</p><p><strong>Materials and methods: </strong>A cycleGAN model was trained with 12,118 sagittal knee MR images and tested on an independent set of 2996 images. Diagnostic interchangeability of synthetic T2*W images was assessed against a series of findings. Voxel intensity of four tissues was evaluated with Bland-Altman plots. Image quality was assessed with the use of root mean squared error (NRMSE), structural similarity index (SSIM) and peak signal-to-noise ratio (PSNR). Code, model and a standalone executable file are provided on github.</p><p><strong>Results: </strong>The model achieved a median NRMSE, PSNR and SSIM of 0.5, 17.4, and 0.5, respectively. Images were found interchangeable with an intraclass correlation coefficient >0.95 for all findings. Mean voxel intensity was equal between synthetic and conventional images. Four types of artifacts were identified: geometrical distortion (86/163 cases), object insertion/omission (11/163 cases), a wrap-around-like (26/163 cases) and an incomplete fat-suppression artifact (120/163 cases), which had a median 0 impact (no impact) on the diagnosis.</p><p><strong>Conclusion: </strong>In conclusion, the developed open-source GAN model creates synthetic T2*W images of the knee of high diagnostic value and quality. The identified artifacts had no or minor effect on the diagnostic value of the images.</p>","PeriodicalId":50928,"journal":{"name":"Academic Radiology","volume":" ","pages":""},"PeriodicalIF":3.8,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143774783","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Contrast Enhancement of Cochlea after Direct Microneedle Intracochlear Injection of Gadodiamide through the Round Window Membrane with Minimal Dosage","authors":"Chaoqun Zhou MS ,&nbsp;Sharon J. Feng MD ,&nbsp;Stephen Leong MD ,&nbsp;Eugénie Breil MD ,&nbsp;François Voruz MD ,&nbsp;Chris Valentini MD ,&nbsp;Daniella R. Hammer MS ,&nbsp;Aykut Aksit PhD ,&nbsp;Elizabeth S. Olson PhD ,&nbsp;Jia Guo PhD, Assistant Professor of Neurobiology ,&nbsp;Jeffrey W. Kysar PhD ,&nbsp;Anil K. Lalwani MD","doi":"10.1016/j.acra.2024.10.022","DOIUrl":"10.1016/j.acra.2024.10.022","url":null,"abstract":"<div><h3>Rationale and Objectives</h3><div>The potential of contrast-enhanced MRI for diagnosing endolymphatic hydrops is limited by long wait times following intravenous (IV) or intratympanic (IT) delivery, high contrast dosages, and inconsistent signal intensity enhancements. This study investigates microneedle-mediated intracochlear (IC) gadodiamide injection for consistent and efficient contrast delivery with minimal contrast dosage.</div></div><div><h3>Materials and Methods</h3><div>A 100 µm diameter microneedle with 35 µm lumen was used to inject 1 µL of diluted gadodiamide (17.4 mM) into a guinea pig cochlea via the round window membrane. Serial MRI imaging was performed in a post-mortem animal using a 9.4 T small-animal MRI. Maximum intensity projections of MRI scans were generated to visualize diffusion of contrast within cochlea over time; mean intensities in defined regions of interest (ROIs) were calculated. Contrast diffusion time and intensity enhancements were determined.</div></div><div><h3>Results</h3><div>Contrast was observed in the basal turn of scala tympani (ST) and scala vestibuli (SV) in the first MRI scan for all subjects which was acquired as early as 35 min after injection. Two-tailed paired t-tests confirmed that contrast reached the first two turns of ST and SV within 60 min, and the second half of third turns and apical turns of ST and SV within 90 min (p &lt; 0.05). Intensity enhancements, defined as the percentage increase of the ROI mean intensity in the injection side compared to the contralateral side, exceeded 100% in the first turn and ranged from 12% to 32% in the third and apical turns of ST and SV at 90 min after injection.</div></div><div><h3>Conclusions</h3><div>IC gadodiamide enables controllable and efficient contrast delivery with significantly lower contrast dosage, making it a viable alternative for contrast-enhanced cochlear MRI.</div></div>","PeriodicalId":50928,"journal":{"name":"Academic Radiology","volume":"32 4","pages":"Pages 2152-2162"},"PeriodicalIF":3.8,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142584936","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Accelerated Spine MRI with Deep Learning Based Image Reconstruction: A Prospective Comparison with Standard MRI","authors":"Jie Li MM ,&nbsp;Yi Xia MD ,&nbsp;Taohu Zhou MM ,&nbsp;Qian Dong MD ,&nbsp;Xiaoqing Lin MM ,&nbsp;Lingling Gu MM ,&nbsp;Song Jiang RT ,&nbsp;Meiling Xu RT ,&nbsp;Xinyi Wan RT ,&nbsp;Guangwen Duan RT ,&nbsp;Dongqing Zhu RT ,&nbsp;Rutan Chen RT ,&nbsp;Zhihao Zhang MSc ,&nbsp;Lei Xiang PhD ,&nbsp;Li Fan MD ,&nbsp;Shiyuan Liu MD","doi":"10.1016/j.acra.2024.11.004","DOIUrl":"10.1016/j.acra.2024.11.004","url":null,"abstract":"<div><h3>Rationale and Objectives</h3><div>To evaluate the performance of deep learning (DL) reconstructed MRI in terms of image acquisition time, overall image quality and diagnostic interchangeability compared to standard-of-care (SOC) MRI.</div></div><div><h3>Materials and Methods</h3><div>This prospective study recruited participants between July 2023 and August 2023 who had spinal discomfort. All participants underwent two separate MRI examinations (Standard and accelerated scanning). Signal-to-noise ratios (SNR), contrast-to-noise ratios (CNR) and similarity metrics were calculated for quantitative evaluation. Four radiologists performed subjective quality and lesion characteristic assessment. Wilcoxon test was used to assess the differences of SNR, CNR and subjective image quality between DL and SOC. Various lesions of spine were also tested for interchangeability using individual equivalence index. Interreader and intrareader agreement and concordance (κ and Kendall τ and W statistics) were computed and McNemar tests were performed for comprehensive evaluation.</div></div><div><h3>Results</h3><div>200 participants (107 male patients, mean age 46.56 ± 17.07 years) were included. Compared with SOC, DL enabled scan time reduced by approximately 40%. The SNR and CNR of DL were significantly higher than those of SOC (P &lt; 0.001). DL showed varying degrees of improvement (0–0.35) in each of similarity metrics. All absolute individual equivalence indexes were less than 4%, indicating interchangeability between SOC and DL. Kappa and Kendall showed a good to near-perfect agreement in range of 0.72–0.98. There is no difference between SOC and DL regarding subjective scoring and frequency of lesion detection.</div></div><div><h3>Conclusion</h3><div>Compared to SOC, DL provided high-quality image for diagnosis and reduced examination time for patients. DL was found to be interchangeable with SOC in detecting various spinal abnormalities.</div></div>","PeriodicalId":50928,"journal":{"name":"Academic Radiology","volume":"32 4","pages":"Pages 2121-2132"},"PeriodicalIF":3.8,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142696077","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Factors Associated with Malignant Biopsy Results for Newly Detected Lesions within One Year after Breast Cancer Surgery","authors":"Arim Yeom MD ,&nbsp;Eun Young Ko MD, PhD ,&nbsp;Chorong Seo MD ,&nbsp;Haejung Kim MD ,&nbsp;Myoung Kyoung Kim MD ,&nbsp;Boo-Kyung Han MD, PhD ,&nbsp;Eun Sook Ko MD, PhD ,&nbsp;Ji Soo Choi MD, PhD","doi":"10.1016/j.acra.2024.10.044","DOIUrl":"10.1016/j.acra.2024.10.044","url":null,"abstract":"<div><h3>Rationale and Objectives</h3><div>This study aimed to identify the factors associated with malignant biopsy results for new lesions within one year after breast cancer surgery.</div></div><div><h3>Materials and Methods</h3><div>This retrospective study included 192 lesions from 186 patients who underwent biopsy for newly developed breast lesions within one year of breast cancer surgery. All patients underwent breast ultrasound (US) at 6 months and breast US with mammography one year after surgery. We analyzed the biopsy results, patient age, characteristics of previous cancers (histologic type, stage, molecular subtype, histologic and nuclear grade, Ki-67 index, extensive intraductal component, lymphovascular invasion (LVI)), history of neoadjuvant chemotherapy (NAC), adjuvant therapy, and characteristics of biopsied lesions (location, mode of detection, imaging features, and Breast Imaging Reporting and Data System category). Multivariate logistic regression was performed to predict malignant results after a biopsy of the new lesion in the early postoperative period.</div></div><div><h3>Results</h3><div>The mean patient age was 49.0 (range, 28–82) years. During follow-up, 137 lesions developed in the ipsilateral remnant breast or mastectomy bed, and 55 lesions developed in the contralateral breast. In total, 37 (19.3%) of the biopsied lesions were malignant, and the following conditions were associated with malignant results in the newly detected lesions: irregularly shaped hypoechoic mass with increased vascularity, presence of previous LVI, history of NAC, and no history of adjuvant radiotherapy or hormone therapy in the indicated patients.</div></div><div><h3>Conclusion</h3><div>Active biopsy may be warranted for new lesions with suspicious imaging findings in the breast or operation bed of patients with LVI, a history of NAC, and no history of adjuvant radiotherapy or hormone therapy, even within one year of breast cancer surgery.</div></div>","PeriodicalId":50928,"journal":{"name":"Academic Radiology","volume":"32 4","pages":"Pages 1838-1850"},"PeriodicalIF":3.8,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142792763","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Quantitative and Visual Benefits of Data-Driven Motion Correction on Oncologic PET/CT: A Prospective Cross-sectional Study","authors":"Semra Ince MD ,&nbsp;M. Allan Thomas PhD ,&nbsp;Malak Itani MD ,&nbsp;Christopher Swingle DO ,&nbsp;Richard Laforest PhD ,&nbsp;Adeel Haq MD ,&nbsp;Genevieve Muñoz MD ,&nbsp;Saeed Ashrafinia PhD ,&nbsp;Paul Schleyer PhD ,&nbsp;Richard L. Wahl MD ,&nbsp;Tyler J. Fraum MD","doi":"10.1016/j.acra.2024.12.016","DOIUrl":"10.1016/j.acra.2024.12.016","url":null,"abstract":"<div><h3>Rationale and Objective</h3><div>Conventional positron emission tomography (PET) respiratory gating utilizes a fraction of acquired PET counts (i.e., optimal gate [OG]), whereas elastic motion correction with deblurring (EMCD) utilizes all PET counts to reconstruct motion-corrected images without increasing image noise. Our aim was to assess the quantitative and visual impacts of EMCD-based motion correction on FDG-PET and DOTATATE-PET images relative to OG and ungated (UG) images.</div></div><div><h3>Materials and Methods</h3><div>This prospective, single-center study enrolled adults undergoing FDG or DOTATATE oncologic PET/CT between June 2020 and October 2022. Subjects underwent a standard-of-care (SOC) PET acquisition while wearing a respiratory gating belt. UG, belt-gating-derived optimal gate (BG-OG), EMCD utilizing belt gating (BG-EMCD), and EMCD utilizing data-driven gating (DDG-EMCD) images were reconstructed. Tracer-avid lesions in the lower chest or upper abdomen were segmented. Quantitative metrics were extracted. Two independent, blinded readers assessed image quality via a 4-point scale and counted lesions on each reconstruction. Differences between reconstructions were assessed via the Wilcoxon signed-rank test (alpha, 0.05).</div></div><div><h3>Results</h3><div>This study enrolled 78 subjects; 36 subjects (mean age, 64.8 years; 20 males) with 136 tracer-avid lesions were analyzed. Data provided are medians across all tracers. Lesion SUV-max was significantly higher (<em>P<!--> </em>&lt;<!--> <!-->0.001) on motion-corrected images (BG-OG: 10.77, BG-EMCD: 10.75, DDG-EMCD: 10.74) than UG images (9.00). Lesion contrast-to-noise ratios (CNRs) were significantly lower (<em>P<!--> </em>&lt;<!--> <!-->0.001) for BG-OG (6.31) and UG images (7.89) than BG-EMCD (9.14) and DDG-EMCD (8.89) images. FDG and DOTATATE subgroup analyses produced similar results. Among motion-corrected images, both readers preferred EMCD-based images to BG-OG images for all tracers (<em>P<!--> </em>&lt;<!--> <!-->0.001) and both subgroups. EMCD-based images occasionally demonstrated more tracer-avid lesions than BG-OG or UG images.</div></div><div><h3>Conclusion</h3><div>EMCD-based motion correction beneficially impacts lesion quantitation (including higher SUVs and CNRs) and overall image quality.</div></div><div><h3>Clinical Impact</h3><div>When employed on capable scanners, EMCD can improve the quality of oncologic PET imaging.</div></div>","PeriodicalId":50928,"journal":{"name":"Academic Radiology","volume":"32 4","pages":"Pages 2257-2269"},"PeriodicalIF":3.8,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143043212","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Are Mock Interviews Worth It? A Different Perspective in a Middle-Income Country","authors":"Ana M. Rendón-Garavito MD ,&nbsp;Juan M. Leguízamo-Isaza MD ,&nbsp;Gustavo Adolfo Triana MD","doi":"10.1016/j.acra.2025.01.040","DOIUrl":"10.1016/j.acra.2025.01.040","url":null,"abstract":"","PeriodicalId":50928,"journal":{"name":"Academic Radiology","volume":"32 4","pages":"Page 2384"},"PeriodicalIF":3.8,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143416160","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Integrating Omics: A New Paradigm in the Management of Hepatocellular Carcinoma","authors":"Aymen Bahsoun MD,&nbsp;Hero K. Hussain MD","doi":"10.1016/j.acra.2025.02.016","DOIUrl":"10.1016/j.acra.2025.02.016","url":null,"abstract":"","PeriodicalId":50928,"journal":{"name":"Academic Radiology","volume":"32 4","pages":"Pages 2330-2333"},"PeriodicalIF":3.8,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143674786","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}