Academic Radiology最新文献

{"title":"Usefulness of [¹⁸F]FAPI-04 and [¹⁸F]FDG PET/CT for the Detection of Peritoneal Carcinomatosis: A Comparative Study.","authors":"Chengzhi Jiang, Kai Zheng, Yanyin Zhang, Xiang Peng, Jian Yang, Hui Ye, Yue Chen","doi":"10.1016/j.acra.2025.05.067","DOIUrl":"10.1016/j.acra.2025.05.067","url":null,"abstract":"<p><strong>Rationale and objectives: </strong>In this study, we aimed to compared the performance of [¹⁸F]FAPI-04 and [¹⁸F]fluorodeoxyglucose (FDG) positron emission tomography/computer tomography (PET/CT) in the evaluation of peritoneal carcinomatosis.</p><p><strong>Materials and methods: </strong>71 patients with suspected peritoneal malignancies were enrolled in our study. All the participants underwent both [¹⁸F]FAPI-04 and [¹⁸F]FDG PET/CT imaging within 7 days. The detection rates, diagnostic accuracies, semiquantitative parameters of the tracers, peritoneal cancer index (PCI) scores, and tumor markers were evaluated and compared.</p><p><strong>Results: </strong>Among the 71 patients, 40 patients were diagnosed with peritoneal carcinomatosis, and 31 were true-negative patients. The sensitivity and accuracy of [¹⁸F]FAPI-04 PET/CT were higher than those of [¹⁸F]FDG PET/CT (sensitivity: 92.50% vs. 72.50%, p=0.003; accuracy: 91.55% vs. 80.28%, p<0.001), particularly in patients with gastric cancer. The SUVmax, tumor-to-liver background ratio (TBR-L), tumor-to-descending aorta ratio (TBR-A), and PCI score were significantly higher for [¹⁸F]FAPI-04 PET/CT than [¹⁸F]FDG PET/CT (all p<0.05). In the [¹⁸F]FAPI-04 PET/CT group, the PCI score, TBR-L, TBR-A, TBR-M and SUVmax were higher in the high level group than the low level group (all p<0.05). The carbohydrate antigen 125 (CA 125) levels were strongly correlated with the PCI of both [¹⁸F]FAPI-04 and [¹⁸F]FDG PET/CT.</p><p><strong>Conclusion: </strong>[¹⁸F]FAPI-04 PET/CT outperformed [¹⁸F]FDG PET/CT in the evaluation of peritoneal carcinomatosis, particularly in patients with gastric cancer. Furthermore, [¹⁸F]FAPI-04 PET/CT may be used for the assessment of peritoneal carcinomatosis in patients, especially FAPI-PCI.</p>","PeriodicalId":50928,"journal":{"name":"Academic Radiology","volume":" ","pages":""},"PeriodicalIF":3.8,"publicationDate":"2025-06-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144337204","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Ultrasound-Guided Radiofrequency Ablation versus Reoperation for Level VI Lymph Nodes Recurrence After Thyroidectomy.","authors":"Xiaoying Lin, Lingpeng Tang, Yuhan Xie, Ting Hu, Songsong Wu","doi":"10.1016/j.acra.2025.05.060","DOIUrl":"10.1016/j.acra.2025.05.060","url":null,"abstract":"<p><strong>Rationale and objectives: </strong>To compare the safety and efficacy of Ultrasound-Guided Radiofrequency Ablation (US-RFA) and reoperation in the management of level VI Lymph nodes (LNs) recurrence after thyroidectomy.</p><p><strong>Methods: </strong>A retrospective analysis was conducted on 74 patients who underwent treatment at Fujian Provincial Hospital between February 2019 and June 2022 for level VI LNs recurrence following thyroidectomy. All patients received either US-RFA or reoperation. The volume reduction rate (VRR) of level VI LNs was evaluated before and after US-RFA. The serum thyroglobulin (Tg) levels, recurrence and complication rates of level VI LNs were recorded and compared between the two groups. Disease progression was analyzed using Kaplan-Meier curves.</p><p><strong>Results: </strong>A total of 37 patients (mean age 48.86 ± 15.81; 25 females) in the US-RFA group and 37 patients (mean age 49.14 ± 15.76; 25 females) in the reoperation group were followed up. There were no statistically significant differences in recurrence-free survival of level VI LNs or Tg levels between the two groups (p > 0.05). The incidence rates of major and minor complications were comparable between the two groups (p > 0.05), but the overall complication rate was significantly higher in the reoperation group compared to the US-RFA group (p < 0.05). Additionally, US-RFA was related to less blood loss, smaller incisions, shorter procedure times, and a reduced length of hospitalization (all p < 0.001).</p><p><strong>Conclusion: </strong>US-RFA is as effective as reoperation for Level VI LNs recurrence after thyroidectomy, offering the advantages of being minimally invasive and associated with fewer complications.</p>","PeriodicalId":50928,"journal":{"name":"Academic Radiology","volume":" ","pages":""},"PeriodicalIF":3.8,"publicationDate":"2025-06-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144337203","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Radiomics for Detection of Prostate Cancer in PI-RADS 3 Lesions: A Systematic Review and Meta-analysis.","authors":"Qian Zhang, Yuxuan Wang, Bing Zhou, Chuanxian Liu, Ping Li, Jianzhi Ji","doi":"10.1016/j.acra.2025.05.062","DOIUrl":"10.1016/j.acra.2025.05.062","url":null,"abstract":"<p><strong>Rationale and objectives: </strong>The noninvasive diagnosis of prostate cancer (PCa) in Prostate Imaging-Reporting and Data System (PI-RADS) 3 lesions remains challenging. The effectiveness of radiomics for detecting PCa in PI-RADS 3 lesions has been explored in some studies, but systematic evidence is still lacking to date. Therefore, this study was conducted to synthesize the effectiveness of radiomics for detecting PCa in PI-RADS 3 lesions.</p><p><strong>Materials and methods: </strong>A systematic search was conducted on Embase, PubMed, Cochrane Library, and Web of Science until September 15, 2024 for studies on the detection performance of radiomics for all PCa and clinically significant PCa (csPCa) in PI-RADS 3 lesions. Quality assessment was performed using the radiomics quality score (RQS).</p><p><strong>Results: </strong>Twelve studies were included, encompassing 2367 PI-RADS 3 lesions in 2340 patients. Meta-analyses revealed that in the validation set, the pooled sensitivity, specificity, and area under the summary receiver operating characteristic curve (AUC) of radiomics were 0.76 (95%CI 0.71-0.80), 0.79 (95%CI 0.72-0.85), and 0.78 (95%CI 0.32-0.96), respectively, for detecting all PCa. In the validation set, the pooled sensitivity, specificity, and AUC of radiomics were 0.76 (95%CI 0.71-0.80), 0.82 (95%CI 0.74-0.88), and 0.77 (95%CI 0.49-0.92), respectively, for detecting csPCa.</p><p><strong>Conclusion: </strong>Radiomics possesses high accuracy in the detection of PCa in PI-RADS 3 lesions. However, both the number and quality of the original studies included were limited, so it is necessary to conduct more prospective, large-sample, multicenter studies in the future.</p>","PeriodicalId":50928,"journal":{"name":"Academic Radiology","volume":" ","pages":""},"PeriodicalIF":3.8,"publicationDate":"2025-06-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144337202","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"\"What Program Directors Think\" VI: Results of the 2024 Survey of the APDR Part 2.","authors":"Angela I Choe, Amita Kamath, Priscilla J Slanetz, Jonathan Swanson, James T Lee, Stephanie P F Yen, Carolynn M DeBenedectis, Jennifer E Gould, Lori Deitte, Anna Rozenshtein","doi":"10.1016/j.acra.2025.06.004","DOIUrl":"10.1016/j.acra.2025.06.004","url":null,"abstract":"<p><strong>Rationale and objectives: </strong>The Association of Program Directors in Radiology (APDR) surveys its members for data gathering on impediments to resident education, variations in resource allocation and recent changes to the American Board of Radiology (ABR) certifying examination.</p><p><strong>Materials and methods: </strong>This was an observational, cross-sectional study using a Web-based survey. Members of the 2022-2023 Annual Survey Committee developed survey questions resulting in 40 items, including demographic data. The survey was distributed by email to all active members of the APDR in January and February of 2024. In this paper, challenges and potential solutions to residency education, current state of resource allocation, PD's opinion on return of the ABR's oral examination, and procedural skills necessary for graduating trainees are presented.</p><p><strong>Results: </strong>The total survey response rate was 31% (84/247). The top five challenges to education were high clinical volumes (88%), insufficient protected time for teaching (64%), remote reaching on clinical rotations (58%) and high focus on relative value units (RVU) (50%). Proposed solutions included dedicated teaching faculty on the rotation schedule, RVU balancing to better value teaching, incentivize on-site faculty, universal, validated teaching resources and increasing the number of residency slots. The results of this survey were presented at the annual Association of Academic Radiology meeting in Boston, MA (April 2024).</p><p><strong>Conclusion: </strong>Survey results find that a quarter of radiology PDs do not receive the full administrative time allocation mandated by the ACGME. The majority of the respondents favor the transition to the ABR oral examination and approve of the 10 procedures created by the APDR Procedures Taskforce. The greatest challenges facing Radiology residency education are a shortage of the radiology workforce, high clinical volumes impeding the balance between education and clinical work, and a lack of engagement and desire for remote work on the part of teaching faculty. Potential solutions to the challenges in Radiology residency education that are likely to decrease burnout and promote faculty interest in education include standardizing work RVUs to account for teaching, developing a cadre of dedicated in-person teaching faculty granted clinical RVU reductions, and facilitating asynchronous teaching.</p>","PeriodicalId":50928,"journal":{"name":"Academic Radiology","volume":" ","pages":""},"PeriodicalIF":3.8,"publicationDate":"2025-06-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144337198","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Imaging the Future: Student Reflections on an Innovative Undergraduate Radiology Course.","authors":"Lulu Liu, Ali Shokralla, Erik Venalainen, Jonathon Leipsic, Waqas Ahmad, Savvas Nicolaou","doi":"10.1016/j.acra.2025.05.070","DOIUrl":"10.1016/j.acra.2025.05.070","url":null,"abstract":"<p><strong>Rationale and objectives: </strong>Radiology plays a critical role in modern healthcare, yet it is often underrepresented in undergraduate education. To address this gap, the University of British Columbia (UBC) introduced RADS 301: exploring imaging in the 21st century, the first undergraduate radiology course of its kind in Canada. This study aims to examine the demographic backgrounds, motivations, and course evaluations of students enrolled in RADS 301.</p><p><strong>Methods: </strong>An anonymous end-of-course survey was administered to students enrolled in RADS 301 during the 2024 academic term. The survey included demographic questions, multiple-choice and Likert-scale items evaluating various aspects of the course, and an open-ended feedback section. Descriptive statistics were used to analyze categorical and ordinal data, while qualitative responses were thematically reviewed.</p><p><strong>Results: </strong>Out of 187 enrolled students, 178 (95%) completed the survey. Students represented a diverse range of academic disciplines, with just over half (55%) enrolled in Health and Life Science majors and the remainder from a variety of other fields, including humanities, business, and arts. Primary motivations for taking the course included general interest in medical topics (78%) and career exploration in healthcare (52%). Course evaluations demonstrated high satisfaction across all domains, with mean ratings ranging from 4.51 (SD = 0.60) to 4.70 (SD = 0.51) on a five-point scale. The overall course rating was 4.76 (SD=0.45). Qualitative responses emphasized the engaging content, diverse instructors, impact on career clarity, and improvements in health literacy.</p><p><strong>Conclusion: </strong>RADS 301 is a promising model for early exposure to radiology and interdisciplinary healthcare education at the undergraduate level. The course was well-received by students from a wide array of backgrounds and appears to enhance interest, knowledge, and confidence in radiology. Findings support the expansion of similar undergraduate courses to foster informed career exploration and promote health literacy.</p>","PeriodicalId":50928,"journal":{"name":"Academic Radiology","volume":" ","pages":""},"PeriodicalIF":3.8,"publicationDate":"2025-06-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144334407","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"CMR-Based Risk Stratification for Adverse Outcomes in Chronic Ischemic Left Ventricular Aneurysm Patients.","authors":"Kairui Bo, Hui Wang, Feifei Zhang, Shuo Shi, Yifeng Gao, Zhen Zhou, Sha Li, Hong Zhang, Lei Xu","doi":"10.1016/j.acra.2025.05.064","DOIUrl":"10.1016/j.acra.2025.05.064","url":null,"abstract":"<p><strong>Rationale and objectives: </strong>Chronic ischemic left ventricular aneurysm (LVA) indicates poor prognosis, yet clinically effective predictive tools for risk stratification are lacking. This study aims to explore the independent risk factors for predicting major adverse cardiovascular events (MACEs) in patients with chronic ischemic LVA, based on clinical data and cardiac magnetic resonance (CMR) imaging features.</p><p><strong>Methods: </strong>From 1825 patients with myocardial infarction, a total of 243 patients with chronic ischemic LVA were enrolled in this study. Predictors of MACEs were identified using univariate Cox regression and the least absolute shrinkage and selection operator (LASSO) algorithm. Multivariate Cox regression analysis was performed to identify independent predictors and construct a nomogram.</p><p><strong>Results: </strong>Over a median follow-up period of 2.6 years, 82 (33.7%) patients experienced MACEs. Independent predictors incorporated into the predictive model were age [hazard ratio (HR) 1.03, p=0.014], New York Heart Association class (HR 1.04, p=0.001), LVA maximum transverse diameter (HR 1.02, p=0.020), extent of late gadolinium enhancement (HR 1.03, p=0.020), and left atrial booster strain (LA-εa; HR 0.84, p<0.001). Incorporating LA-εa significantly improved model discrimination (ΔC-index = 0.037, p<0.001) and reclassification (integrated discrimination improvement=0.100, net reclassification improvement=0.357, all p<0.001).</p><p><strong>Conclusion: </strong>The integration of clinical and CMR biomarkers, particularly LA-εa, is effective for predicting adverse outcomes in patients with chronic ischemic LVA.</p>","PeriodicalId":50928,"journal":{"name":"Academic Radiology","volume":" ","pages":""},"PeriodicalIF":3.8,"publicationDate":"2025-06-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144334406","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Predictive Value of Dry Brain Sign for Open Spina Bifida at First Trimester Anomaly Scan: A Case-Control study.","authors":"Hesham Kamal El Din Abd El Fatah El Emam, Hend Galal Eldeen Mohamed Ali Hassan, Sahar Mohamed El Feky, Ahmed Mohamed Osman","doi":"10.1016/j.acra.2025.04.069","DOIUrl":"https://doi.org/10.1016/j.acra.2025.04.069","url":null,"abstract":"<p><strong>Rationale and objectives: </strong>Spina bifida is a common neural tube defect resulting from incomplete closure of the spinal column, with early detection crucial for prenatal management. This work aimed to assess the diagnostic utility of the dry brain sign in first-trimester sonographic screening for open spina bifida (OSB).</p><p><strong>Materials and methods: </strong>This prospective case-control study included 50 pregnant women (aged 18-40 years) who underwent first-trimester ultrasound screening for singleton pregnancies. Participants were divided into two equal groups: 25 controls with normal ultrasound findings and 25 cases exhibiting a positive \"dry brain sign,\" defined by enlarged choroid plexuses without surrounding cerebrospinal fluid. Second and third-trimester ultrasound findings were used to confirm OSB diagnoses.</p><p><strong>Results: </strong>The case group exhibited significantly higher mean choroid plexus (CP) length, CP to occipitofrontal diameter (CP/OFD), and CP to biparietal diameter (CP/BPD) ratio (p= 0.001). BPD and OFD were significantly lower in the case group compared with the controls (p= 0.001). CP/BPD and CP/OFD demonstrated the highest diagnostic accuracy (100%) with optimal sensitivity and specificity. CP/BPD (cutoff ≥0.65, p < 0.001) and mean BPD (cutoff ≤20.5 mm, p < 0.001) were reliable markers for OSB.</p><p><strong>Conclusion: </strong>Dry brain sign could be used as sonographic markers for early screening in the first trimester for OSB by using mean CP/BPD ratio and mean CP/OFD ratios.</p>","PeriodicalId":50928,"journal":{"name":"Academic Radiology","volume":" ","pages":""},"PeriodicalIF":3.8,"publicationDate":"2025-06-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144327657","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Differential Alterations of Supraspinal Somatosensory Pathways in Complete and Incomplete Spinal Cord Injury Patients: A Task-Based fMRI Study.","authors":"Haotian Xin, Beining Yang, Yu Wang, Ling Wang, Qunya Qi, Xianglin Guo, Yulong Jia, Weimin Zheng, Xin Chen, Fang Li, Chuchu Sun, Jie Lu, Nan Chen","doi":"10.1016/j.acra.2025.05.057","DOIUrl":"https://doi.org/10.1016/j.acra.2025.05.057","url":null,"abstract":"<p><strong>Rationale and objectives: </strong>We aimed to investigate the different brain activation patterns and alterations in somatosensory pathways in complete spinal cord injury (CSCI) and incomplete spinal cord injury (ISCI) patients and to provide a theoretical basis for the rehabilitation of somatosensory function in SCI patients.</p><p><strong>Materials and methods: </strong>Fifteen CSCI patients, 15 ISCI patients and 24 healthy controls (HCs) underwent somatosensory stimulation tasks during brain functional magnetic resonance imaging. The brain activation patterns were compared. On the basis of evidence from the underlying somatosensory pathways, several somatosensory-related brain regions were selected as regions of interest (ROIs). Granger causality analysis (GCA)-an effective connectivity (EC) analysis technique-was used to measure the directional functional information flow among the aforementioned ROIs to detect alterations in the somatosensory pathways.</p><p><strong>Results: </strong>Regarding brain activation patterns, compared with the ISCI and HCs groups, the CSCI group presented significant decreases in brain activation intensity in the bilateral insula (INS) and Rolandic operculum (ROL) (cluster-level FDR correction with p < 0.05). GCA-based EC calculations revealed that compared with the ISCI group, the CSCI group presented lower EC from the right thalamus and INS to the right postcentral gyrus (PoCG) (p < 0.001; p = 0.003; separately). Compared with HCs group, decreased ECs from the right ROL to the right PoCG were found in both the CSCI and ISCI groups (p = 0.001; p = 0.006; separately).</p><p><strong>Conclusion: </strong>In conclusion, CSCI and ISCI patients exhibited different brain activations and alterations in somatosensory pathways, laying the theoretical foundation for somatosensory rehabilitation in SCI patients.</p>","PeriodicalId":50928,"journal":{"name":"Academic Radiology","volume":" ","pages":""},"PeriodicalIF":3.8,"publicationDate":"2025-06-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144318611","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Accuracy of CT-Based Radiomics Models for Preoperative Grading of Clear Cell Renal Cell Carcinoma: A Systematic Review and Meta-analysis.","authors":"Nima Broomand Lomer, Sepideh Abdi, Mohammad Amin Ashoobi, Amir Mahmoud Ahmadzadeh, Amirhosein Ghasemi, Drew A Torigian","doi":"10.1016/j.acra.2025.05.049","DOIUrl":"https://doi.org/10.1016/j.acra.2025.05.049","url":null,"abstract":"<p><strong>Purpose: </strong>High-grade clear cell renal cell carcinoma (ccRCC) is linked to aggressive behavior, higher metastatic potential, and poor overall prognosis. This study aims to assess the diagnostic performance of CT-based radiomics models for preoperative differentiation of high-grade from low-grade ccRCC.</p><p><strong>Methods: </strong>A comprehensive systematic search was conducted across PubMed, Scopus, and Embase. Study quality was evaluated using the QUADAS-2 and METRICS tools. Pooled estimates of sensitivity, specificity, positive likelihood ratio (PLR), negative likelihood ratio (NLR), diagnostic odds ratio (DOR), and area under the curve (AUC) were calculated using a bivariate random-effects model. Separate comparative analyses were performed based on tumor grading system, imaging phase, and model type. Subgroup analysis was performed to identify potential sources of heterogeneity. Sensitivity analysis was conducted to identify potential outliers. Publication bias was assessed using Deek's funnel plot asymmetry test.</p><p><strong>Results: </strong>A total of 49 studies, encompassing 11,125 patients and 11,922 lesions, were included in the review. Of these, 27 studies were eligible for meta-analysis. The pooled performance of the radiomics model demonstrated a sensitivity of 0.79, specificity of 0.85, PLR of 4.6, NLR of 0.30, DOR of 19.21, and AUC of 0.88. Pooled sensitivity exhibited substantial heterogeneity (I²=51.4%), while heterogeneity for other estimates was minimal. Studies using WHO/ISUP tumor grading system showed higher pooled sensitivity compared to those using Fuhrman grading system (Sensitivity: 0.81 vs 0.71, p=0.03, AUC: 0.88 vs. 0.82, p<0.001). Combined models performed comparably to radiomics-only models (AUC: 0.87 vs. 0.85, p=0.1). Nephrographic phase (AUC: 0.67) showed inferior performance compared to corticomedullary phase (AUC: 0.82) and non-contrast images (AUC: 0.83). No considerable publication bias was observed (p=0.73).</p><p><strong>Conclusion: </strong>CT-based radiomics models have demonstrated promise as non-invasive tools for grading ccRCC and may serve as valuable adjuncts in clinical practice.</p>","PeriodicalId":50928,"journal":{"name":"Academic Radiology","volume":" ","pages":""},"PeriodicalIF":3.8,"publicationDate":"2025-06-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144318631","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"MRI Radiomics and MAGIC Technology in Breast Cancer NAC Response Assessment.","authors":"Chao Gao, Xiaohong Xue","doi":"10.1016/j.acra.2025.05.038","DOIUrl":"https://doi.org/10.1016/j.acra.2025.05.038","url":null,"abstract":"","PeriodicalId":50928,"journal":{"name":"Academic Radiology","volume":" ","pages":""},"PeriodicalIF":3.8,"publicationDate":"2025-06-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144303432","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}