European Heart Journal - Imaging Methods and Practice最新文献

{"title":"Cumulative radiation dose from medical imaging in pediatric congenital heart disease patients with epicardial cardiac implantable electronic devices","authors":"O. Aboyewa, C. Laternser, Andrada Popescu, Nicole Murphy, Dhaivat Shah, Michael Monge, Cynthia Rigsby, L. Golestanirad, Gregory Webster, Daniel Kim","doi":"10.1093/ehjimp/qyae060","DOIUrl":"https://doi.org/10.1093/ehjimp/qyae060","url":null,"abstract":"\u0000 \u0000 \u0000 To determine whether pediatric congenital heart disease (CHD) patients with epicardial cardiac implantable electronic devices (CIEDs) receive high cumulative effective doses (CED) of ionizing radiation from medical imaging tests.\u0000 \u0000 \u0000 \u0000 We compared 28 pediatric CHD patients with epicardial CIEDs (cases) against 40 patients with no CIED matched by age at operation, sex, surgical era, and CHD diagnosis (controls). We performed a retrospective review of radiation exposure from medical imaging exams between 2006 and 2022. Radiation dose from computed tomography (CT) and X-ray radiography was calculated using the National Cancer Institute radiation dosimetry tool. We performed univariate analysis to compare the CED between the two groups. In the case subgroup, we convened experts review to adjudicate the prevalence of CT exams that should have been performed with MRI in the absence of a CIED. Children (median age 2.5 years at implant) with CIEDs received significantly higher median CED compared to matched controls (6.90 vs. 1.72 mSv, p = 0.0018). In cases, expert adjudication showed that 80% of the CT exams would have been performed with MRI in the absence of a CIED. This resulted, on average, a 5-fold increase in the ED from post-lead implant CTs.\u0000 \u0000 \u0000 \u0000 Pediatric CHD patients with CIED received four times higher CED than matched controls. Improved access to medical imaging tests without ionizing radiation, such as MRI, could potentially reduce the ED in CIED patients by up to five times.\u0000","PeriodicalId":508944,"journal":{"name":"European Heart Journal - Imaging Methods and Practice","volume":"32 20","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-06-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141346244","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Variability in Approach to Exercise Stress Echocardiography for Diagnosis of Heart Failure with Preserved Ejection Fraction -An International Survey on Real-World Practice","authors":"Yuta Tani, Y. Reddy, Frederik H Verbrugge, Jeong Hoon Yang, Kazuaki Negishi, T. Harada, Kazuki Kagami, Yuki Saito, Naoki Yuasa, H. Sorimachi, Fumitaka Murakami, T. Kato, N. Wada, H. Ishii, M. Obokata","doi":"10.1093/ehjimp/qyae059","DOIUrl":"https://doi.org/10.1093/ehjimp/qyae059","url":null,"abstract":"\u0000 \u0000 \u0000 The diagnosis of heart failure with preserved ejection fraction (HFpEF) remains challenging based on resting assessments. Exercise echocardiography is often used to unmask abnormalities that develop during exercise, but the diagnostic criteria have not been standardized. This study aimed to elucidate how cardiologists utilize exercise echocardiography to diagnose HFpEF in real-world practice.\u0000 \u0000 \u0000 \u0000 An international web-based survey involving 87 cardiologists was performed. We also performed a retrospective cross-sectional study to investigate the impact of different exercise echocardiographic diagnostic criteria in 652 dyspneic patients who underwent exercise echocardiography. The HFA-PEFF algorithm was the most commonly used exercise echocardiography criterion for HFpEF diagnoses (48%), followed by the ASE/EACVI criteria (24%) and other combinations of multiple parameters (22%). Among 652 patients, the proportion of HFpEF diagnosis varied substantially according to the criteria used ranging from 20.1% (ASE/EACVI criteria) to 44.3% (HFA-PEFF algorithm). Many cases (49.4-70.5%) remained indeterminate after exercise echocardiography, but only 41% of surveyed cardiologists would utilize exercise right heart catheterization to resolve an indeterminate result. Despite these diagnostic uncertainties, 54% of surveyed cardiologists would utilize exercise echocardiography results to initiate sodium-glucose co-transporter 2 inhibitors.\u0000 \u0000 \u0000 \u0000 In real-world practice, exercise echocardiographic criteria utilized across cardiologists vary, which meaningfully impacts the frequency of HFpEF diagnoses, with indeterminate results being common. Despite these diagnostic uncertainties, many cardiologists initiate pharmacotherapy based on exercise echocardiography. The lack of consensus on universal diagnostic criteria for exercise echocardiography and approaches to indeterminate results may limit the delivery of evidence-based treatment for HFpEF.\u0000","PeriodicalId":508944,"journal":{"name":"European Heart Journal - Imaging Methods and Practice","volume":"73 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-06-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141350390","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Atrial septal defect closure in children at young age is beneficial for left ventricular function","authors":"Pia Sjöberg, Henning Clausen, H. Arheden, P. Liuba, Erik Hedström","doi":"10.1093/ehjimp/qyae058","DOIUrl":"https://doi.org/10.1093/ehjimp/qyae058","url":null,"abstract":"\u0000 \u0000 \u0000 Atrial septal defects (ASD) lead to volume-loaded right ventricles (RV). Atrial septal defect closure does not always improve symptoms or exercise capacity, possibly explained by impaired left ventricular (LV) hemodynamics.\u0000 The study evaluated the effect of ASD closure in children using non-invasive LV pressure-volume (PV) loops derived from cardiac magnetic resonance imaging (CMR) and brachial blood pressure, compared with controls.\u0000 \u0000 \u0000 \u0000 Twenty-three children with ASD underwent CMR, 17 of these were re-examined 7 [6–9] months after ASD closure. Twelve controls were included. Hemodynamic variables were derived from PV loops by time-resolved LV volumes and brachial blood pressure. After ASD closure, LV volume increased (76 [70–86] ml/m2 vs 63 [57–70] ml/m2, p=0.0001), however was still smaller than in controls (76 [70–86] ml/m2 vs 82 [78–89] ml/m2, p=0.048). Compared to controls, children with ASD had higher contractility (2.6 [2.1–3.3] mmHg/ml vs 1.7 [1.5–2.2] mmHg/ml, p=0.0076) and arterial elastance (2.1 [1.4–3.1] mmHg/ml vs 1.4 [1.2–2.0] mmHg/ml, p=0.034). After ASD closure, both contractility (2.0 [1.4–2.5] mmHg/ml, p=0.0001) and arterial elastance (1.4 [1.3–2.0] mmHg/ml, p=0.0002) decreased.\u0000 \u0000 \u0000 \u0000 Despite the left-to-right atrial shunt that leads to low LV filling and RV enlargement, the LV remains efficient and there is no evidence of impaired LV hemodynamics in children. Closure of ASD at young age while the ventricle is compliant is thus beneficial for LV function. Left ventricular volumes however remained small after ASD closure, which may impact long-term cardiovascular risk and exercise performance.\u0000","PeriodicalId":508944,"journal":{"name":"European Heart Journal - Imaging Methods and Practice","volume":" 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-06-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141370368","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Coronary coding in dTGA pre- and post-ASO - verification and necessary corrections following adult CMR","authors":"Hedwig H Hövels-Gürich, Corinna Lebherz, R. Dettori, Andreas Pütz, Anca Racolta, Katharina Linden, A. Kirschfink, Ertunc Altiok, André Rüffer, Nikolaus Marx, Ulrike Herberg, M. Frick","doi":"10.1093/ehjimp/qyae055","DOIUrl":"https://doi.org/10.1093/ehjimp/qyae055","url":null,"abstract":"\u0000 \u0000 \u0000 In adult patients with transposition of the great arteries (dTGA) after arterial switch operation (ASO), the coronary artery circulation after neonatal surgical transfer remains a major culprit for long-term sequelae, including myocardial ischemia and sudden cardiac death. As coronary imaging in paediatric age is often incomplete and classification mainly relies on surgeon’s description in the operation report, we intended to develop a systematic, understandable pattern of the coronary status for each young patient, combing unambiguous coding with non-invasive imaging.\u0000 \u0000 \u0000 \u0000 The monocentric prospective study evaluated 89 young adults (mean 23 years) after ASO for dTGA including cardiac magnetic resonance (CMR) coronary angiography. Following “The Leiden Convention coronary coding system”, we describe the systematic transformation process and provide a graphical illustration considering surgical and imaging views for the 6 main coronary types, followed by comparison with adult CMR. Discordance between surgeon’s and CMR classification is evaluated.\u0000 In 7 (7.9%) patients, a discordance between the surgeon’s postoperative and the CMR classification was found; therefore, the initial classification had to be corrected according to adult CMR. Three cases (3.4%) with particularly challenging coronary variants (intramural and inter-arterial course, functional common ostium) are presented.\u0000 \u0000 \u0000 \u0000 Considering the risks of a possible neonatal coronary misclassification and of increasing additional acquired coronary artery disease with age, a reliable cooperation between surgeons, cardiologists and imaging specialists must be ensured. Therefore, after completion of growth, a systematic pattern of the coronary artery status, combing unambiguous coding with CMR imaging, should be established for each patient.\u0000","PeriodicalId":508944,"journal":{"name":"European Heart Journal - Imaging Methods and Practice","volume":"27 28","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-06-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141379932","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of epicardial adipose tissue on diastolic dysfunction in patients with chronic coronary syndrome and preserved left ventricular ejection fraction","authors":"Hirotoshi Ishikawa, Takatoshi Sugiyama, Kenichiro Otsuka, H. Yamaura, K. Hojo, Y. Kono, Asahiro Ito, Takanori Yamazaki, K. Shimada, N. Kasayuki, Daiju Fukuda","doi":"10.1093/ehjimp/qyae056","DOIUrl":"https://doi.org/10.1093/ehjimp/qyae056","url":null,"abstract":"\u0000 \u0000 \u0000 To investigate the association between left ventricular diastolic dysfunction (LVDD) and epicardial adipose tissue (EAT) accumulation in patients with chronic coronary syndrome (CCS).\u0000 \u0000 \u0000 \u0000 The study included 314 patients with preserved left ventricular ejection fraction who underwent coronary computed tomographic angiography (CCTA) and thoracic tissue Doppler echocardiography (TTDE). The EAT volume was measured using CCTA. LVDD was categorized into three groups: absent LVDD, undetermined LVDD, and LVDD. Multivariate logistic regression analysis was performed to assess the association between the clinical parameters, TTDE and CCTA findings, and LVDD. Patients (mean age: 66±13 years; 52% men) were divided into LVDD present (30 patients, 9.6%), LVDD absent (219 patients, 69.7%), and LVDD undetermined (65 patients, 20.7%) groups. CCTA showed that patients with LVDD had a significantly higher coronary artery calcium (CAC) score and % plaque volume (%PV) than those without LVDD, whereas the prevalence of obstructive coronary artery disease was comparable between the groups. The EAT volume index correlated with each LVDD diagnostic component, except for tricuspid regurgitation velocity. A multivariate model showed that age [odds ratio (OR), 1.13; p < 0.001] and EAT volume index (OR, 1.02; p = 0.038) were independently associated with LVDD, even after adjusting for LV mass index (OR, 1.05; p = 0.005). There was no significant association between the CAC score and %PV or LVDD.\u0000 \u0000 \u0000 \u0000 This study demonstrated that EAT volume index and LV mass were robust predictors of LVDD; however, there was no independent association between coronary atherosclerotic disease burden and LVDD.\u0000","PeriodicalId":508944,"journal":{"name":"European Heart Journal - Imaging Methods and Practice","volume":"10 7","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-06-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141383608","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Where have the microbubbles come from? Left Inferior Pulmonary Arteriovenous Fistula detected by Transesophageal Echocardiography","authors":"R. Horita, D. Hachinohe, Y. Kasai, Ryo Otake, Hidemasa Shitan, Tsutomu Fujita","doi":"10.1093/ehjimp/qyae052","DOIUrl":"https://doi.org/10.1093/ehjimp/qyae052","url":null,"abstract":"","PeriodicalId":508944,"journal":{"name":"European Heart Journal - Imaging Methods and Practice","volume":"4 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141099714","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Awareness of strengths and weaknesses of Cardiovascular Magnetic Resonance Imaging (CMR) – Results from a questionnaire survey","authors":"Victoria Zieschang, Rebecca Elisabeth Beyer, Maximilian Leo Müller, Frederike Trautmann, Titus Kühne, Eike Nagel, Andreas Rolf, Andreas Schuster, Grigorios Korosoglou, Henning Steen, Ali Yilmaz, Steffen E Petersen, Bjoern Andrew Remppis, Gisela Thiede, Anna Clara Nolden, Sebastian Kelle","doi":"10.1093/ehjimp/qyae050","DOIUrl":"https://doi.org/10.1093/ehjimp/qyae050","url":null,"abstract":"\u0000 \u0000 \u0000 Extensive research has established cardiovascular magnetic resonance (CMR) as a powerful tool for diagnosing and monitoring various cardiovascular diseases (CVD). However, CMR has yet to reach its full potential in routine clinical care, which is mainly due to reimbursement issues. Among other factors, overcoming this gap requires adequate awareness among healthcare professionals and potential patients, the extent of which is currently unknown. Therefore, we conducted a survey to assess awareness and identify knowledge gaps regarding the clinical role and socio-economic factors associated with CMR.\u0000 \u0000 \u0000 \u0000 144 subjects not involved in direct patient care were enrolled at a German health conference and completed a 24-item survey, including procedural, clinical and socio-economic questions about CMR. Respondents were well aware of the socio-economic impact of CVD. Common CMR indications were correctly identified by most participants, but only 22.9% knew the full spectrum. Participants underestimated the modality’s benefits, such as absence of ionizing radiation and rare allergic reactions to contrast agents (only 70.9% and 37.6% correct answers, respectively). Respondents estimated the therapeutic guidance of CMR to be high (50.7% voted impact >50%) and the annual demand to be increasing (89.9%). Attitudes towards CMR were generally positive, with 77.1% of participants willing to travel >25km and 60.4% willing to pay >125 Euros to have a CMR examination.\u0000 \u0000 \u0000 \u0000 Despite great interest in CMR, significant knowledge gaps hinder its optimal use in clinical practice. The development and implementation of awareness and education strategies are needed to realize the full clinical potential of CMR.\u0000","PeriodicalId":508944,"journal":{"name":"European Heart Journal - Imaging Methods and Practice","volume":"15 12","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141107011","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cardiac power output is associated with adverse outcomes in patients with preserved ejection fraction after transcatheter aortic valve implantation","authors":"Daisuke Miyahara, M. Izumo, Yukio Sato, Tatsuro Shoji, Mitsuki Yamaga, Yoshikuni Kobayashi, T. Kai, T. Okuno, S. Kuwata, M. Koga, Yasuhiro Tanabe, Y. Akashi","doi":"10.1093/ehjimp/qyae048","DOIUrl":"https://doi.org/10.1093/ehjimp/qyae048","url":null,"abstract":"\u0000 \u0000 \u0000 Cardiac power output (CPO) measures cardiac performance, and its prognostic significance in heart failure with preserved ejection fraction (EF) has been previously reported. However, the effectiveness of CPO in risk stratification of patients with valvular heart disease and postoperative valvular disease has not been reported. We aimed to determine the association between CPO and clinical outcomes in patients with preserved left ventricular (LV) EF after transcatheter aortic valve implantation (TAVI).\u0000 \u0000 \u0000 \u0000 This retrospective observational study included 1047 consecutive patients with severe aortic stenosis after TAVI. All patients were followed up for all-cause mortality and hospitalization for HF. CPO was calculated as 0.222×cardiac output × mean blood pressure (BP)/LV mass, where 0.222 was the conversion constant to W/100 g of the LV myocardium. CPO was assessed using transthoracic echocardiography at discharge after TAVI. Of the 1047 patients, 253 were excluded following the exclusion criteria, including those with low LVEF, and 794 patients (84.0 [80.0–88.0] years; 35.8% male) were included in this study. During a median follow-up period of 684 (237–1114) days, the composite endpoint occurred in 196 patients. A dose-dependent association was observed between the CPO levels and all-cause mortality. Patients in the lowest CPO tertile had significantly lower event-free survival rates (log-rank test, p = 0.043). Multivariate Cox regression analysis showed that CPO was independently associated with adverse outcomes (hazard ratio = 0.561, p = 0.020). CPO provided an incremental prognostic effect in the model based on clinical and echocardiographic markers (p = 0.034).\u0000 \u0000 \u0000 \u0000 CPO is independently and incrementally associated with adverse outcomes in patients with preserved LVEF following TAVI.\u0000","PeriodicalId":508944,"journal":{"name":"European Heart Journal - Imaging Methods and Practice","volume":"122 25","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141115588","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"ECG-Gated CT improves Diagnosis in Prosthetic Valve Degeneration","authors":"Jonathan X Fang, T. Frisoli, G. Giustino, P. Villablanca, Pedro E Gonzalez, B. O'Neill, DeeDee Wang, William W. O’Neill, James C Lee","doi":"10.1093/ehjimp/qyae049","DOIUrl":"https://doi.org/10.1093/ehjimp/qyae049","url":null,"abstract":"","PeriodicalId":508944,"journal":{"name":"European Heart Journal - Imaging Methods and Practice","volume":"105 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141115827","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Differential Culprit Plaque Morphology in Acute Coronary Syndrome: A Comparison Between Very Young Patients (<=35 Years) and Older Counterparts Using Optical Coherence Tomography","authors":"G. Chaudhary, B. Gupta, Shubhajeet Roy, S. Chandra, Akhil Sharma, A. Pradhan, M. Bhandari, P. Vishwakarma, R. Sethi, S. Dwivedi, Vinit Baliyan, Prachi Sharma, Vikash Jaiswal, Abhishek Singh, A. Shukla, Sajina Shrestha, Alessia Gimelli","doi":"10.1093/ehjimp/qyae046","DOIUrl":"https://doi.org/10.1093/ehjimp/qyae046","url":null,"abstract":"\u0000 \u0000 \u0000 Underlying mechanisms responsible for acute coronary syndrome (ACS) in young patients compared to older counterparts are yet to be explored with optical coherence tomography (OCT).\u0000 \u0000 \u0000 \u0000 To explore underlying mechanisms of ACS in ≤35 (very young) and >35-year-old (older counterparts) ACS patients using OCT.\u0000 \u0000 \u0000 \u0000 This was a prospective, single-center, investigational study. Patients were divided into groups according to age (≤35 and >35 years) and further subdivided according to the underlying mechanism i.e. plaque rupture (PR) and plaque erosion (PE).\u0000 \u0000 \u0000 \u0000 A total of 93 patients were analyzed. Thin cap fibroatheroma (TCFA) was significantly higher among older counterparts than very young patients for both PR (80.0% vs. 31.8%, p=0.002) and PE (66.7% vs. 6.3%, p<0.001) groups. Micro-channels were also significantly more prevalent among older than very young patients for both PR (65.0% vs. 18.2%, p=0.004) and PE groups (55.6% vs.12.5%, p=0.013). Macrophages were significantly higher in older than very young patients for both PR (25.0% vs. 0%, p=0.018) and PE (44.4% vs. 0%, p=0.003) groups. In contrast, fibrous cap thickness was greater in very young than older patients for both PR (105.71±48.02 µm vs. 58.00±15.76 µm, p<0.001) and PE (126.67±48.22 µm vs. 54.38±24.21 µm, p<0.001) groups. Intimal thickness was greater in older than very young patients for both PR (728.00±313.92 µm vs. 342.27±142.02 µm, p<0.001) and PE (672.78±334.57 µm vs. 295.00±99.60 µm, p<0.001) groups.\u0000 \u0000 \u0000 \u0000 Frequency of TCFA, micro-channels, macrophages, and intimal thickness was significantly higher in older ACS patients compared to very young patients. However, fibrous cap thickness was significantly greater in very young ACS patients compared to older patients.\u0000","PeriodicalId":508944,"journal":{"name":"European Heart Journal - Imaging Methods and Practice","volume":"119 26","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141115510","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}