European Heart Journal - Imaging Methods and Practice最新文献

{"title":"CMR characterisation of patients with heart failure and Left Bundle Branch Block","authors":"Raluca Tomoaia, Peter Harrison, Lydia Bevis, A. Wahab, Patrick Thompson, Christopher ED Saunderson, Eylem Levelt, Erica Dall’Armellina, Pankaj Garg, John P Greenwood, Sven Plein, Peter P Swoboda","doi":"10.1093/ehjimp/qyae047","DOIUrl":"https://doi.org/10.1093/ehjimp/qyae047","url":null,"abstract":"\u0000 \u0000 \u0000 We aimed to identify the distinctive cardiovascular magnetic resonance (CMR) features of patients with left bundle branch block (LBBB) and heart failure with reduced ejection fraction (HFrEF) of presumed non-ischaemic aetiology. The secondary aim was to determine whether these individuals exhibit characteristics that could potentially serve as predictors of left ventricular ejection fraction (LVEF) recovery as compared to patients without LBBB.\u0000 \u0000 \u0000 \u0000 We prospectively recruited patients with HFrEF (LVEF ≤40%) on echocardiography who were referred for early CMR examination. Patients with an established diagnosis of coronary artery disease and known structural or congenital heart disease were excluded. LV recovery was defined as achieving ≥10% absolute improvement to ≥40% in LVEF between baseline evaluation to CMR.\u0000 \u0000 \u0000 \u0000 A total of 391 patients were recruited including 115 (29.4%) with LBBB. Compared to HF patients without LBBB, those with LBBB exhibited larger left ventricles and smaller right ventricles, but no differences were observed with respect to LVEF (35.8 ± 12 vs. 38 ± 12 %, p=0.105). The overall rate of LV recovery from baseline echocardiogram to CMR (70 [42 - 128] days) was not significantly different between LBBB and non-LBBB patients (27.8% vs. 31.5%, p=0.47). Reduced LVEF remained an independent predictor of LV non-recovery only in patients with LBBB.\u0000 \u0000 \u0000 \u0000 Patients presenting with HFrEF and LBBB had larger LV cavities and smaller RV cavities than those without LBBB but no difference in prevalence of scar or ischaemia. The rates of LV recovery were similar between both groups, which supports current guidelines to defer device therapy until 3-6 months of GDMT, rather than early CMR and device implantation.\u0000","PeriodicalId":508944,"journal":{"name":"European Heart Journal - Imaging Methods and Practice","volume":"54 13","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140965776","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Artificial Intelligence Based Quantitative Myocardial Blood Flow Assessment Facilitates the Detection of Multi-Vessel Coronary Artery Disease Following Vasodilator Stress Perfusion Cardiovascular MR Imaging","authors":"Georgios Moutzoukis, Benedikt Wagner, Marie K Lorenz, Heiko Mahrholdt, A. Seitz","doi":"10.1093/ehjimp/qyae045","DOIUrl":"https://doi.org/10.1093/ehjimp/qyae045","url":null,"abstract":"","PeriodicalId":508944,"journal":{"name":"European Heart Journal - Imaging Methods and Practice","volume":"13 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140966878","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cardiac diffusion tensor imaging approaching cellular length scales reveals striking microstructural detail","authors":"I. Teh, Erica Dall'Armellina, Jurgen E Schneider","doi":"10.1093/ehjimp/qyae043","DOIUrl":"https://doi.org/10.1093/ehjimp/qyae043","url":null,"abstract":"","PeriodicalId":508944,"journal":{"name":"European Heart Journal - Imaging Methods and Practice","volume":"4 5","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140967770","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Joint shape/texture representation learning for cardiovascular disease diagnosis from MRI","authors":"Xiang Chen, Yan Xia, Erica Dall'Armellina, N. Ravikumar, A. F. Frangi","doi":"10.1093/ehjimp/qyae042","DOIUrl":"https://doi.org/10.1093/ehjimp/qyae042","url":null,"abstract":"\u0000 \u0000 \u0000 Cardiovascular diseases (CVDs) are the leading cause of mortality worldwide. Cardiac image and mesh are two primary modalities to present the shape and structure of the heart and have been demonstrated to be efficient in CVD prediction and diagnosis. However, previous research has been generally focused on a single modality (image or mesh), and few of them have tried to jointly consider the image and mesh representations of heart. To obtain efficient and explainable biomarkers for CVD prediction and diagnosis, it is needed to jointly consider both representations.\u0000 \u0000 \u0000 \u0000 We design a novel multi-channel variational auto-encoder (VAE), MIVAE, to learn joint representation of paired mesh and image. After training, the shape-aware image representation (SAIR) can be learned directly from the raw images and applied for further CVD prediction and diagnosis. We demonstrate our method on data from UK Biobank (UKBB) study and two other datasets via extensive experiments. In acute myocardial infarction prediction, SAIR achieves 81.43% accuracy, significantly higher than traditional biomarkers like Metadata and clinical indices (left ventricle and right ventricle clinical indices of cardiac function like chamber volume, mass, ejection fraction, etc.).\u0000 \u0000 \u0000 \u0000 Our MIVAE provides a novel approach for 3D cardiac mesh reconstruction from images. The extraction of SAIR is fast and without need of segmentation masks, and its focusing can be visualised in the corresponding cardiac meshes. SAIR archives better performance than traditional biomarkers and can be applied as an efficient supplement to them, which is of significant potential in CVD analysis.\u0000","PeriodicalId":508944,"journal":{"name":"European Heart Journal - Imaging Methods and Practice","volume":"4 5","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140982108","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparing Flow And Pulmonary Artery Growth Post PDA Stenting In Patients With Ductal-Dependent Pulmonary Flow Using Four-Dimensional Magnetic Resonance Imaging (4D Flow MRI)","authors":"F. Al Kindi, H. A. Al Kindi, M. Maddali, A. Al Farqani, K. Al Alawi, A. Al Balushi, M. Al Ghafri, S. Khalil, S. Kumar","doi":"10.1093/ehjimp/qyae044","DOIUrl":"https://doi.org/10.1093/ehjimp/qyae044","url":null,"abstract":"\u0000 \u0000 \u0000 The Four-Dimensional Magnetic Resonance Imaging (4D Flow MRI) provides a qualitative and quantitative assessment of cardiovascular structures and processes. 4D flow MRI was used to study pulmonary flow in post-patent ductus arteriosus (PDA) stent insertion in duct-dependent pulmonary flow neonates at baseline (PDA stent insertion) and after 6 months. Also, to evaluate effect of flow dynamics on growth of pulmonary arteries.\u0000 \u0000 \u0000 \u0000 This prospective observational study included neonates with ductus arteriosus-dependent pulmonary circulation who underwent ductal stenting between June 2021 and November 2022.Cardiac 4D flow MRI and magnetic resonance angiography (MRA) were conducted in 2 phases; after the deployment of the PDA stent during the neonatal period and after 6 months from stent deployment.\u0000 \u0000 \u0000 \u0000 Eight neonates were recruited, but only five completed both scans. A total of 10 pulmonary arteries were evaluated during each phase. The median LPA and RPA diameters and indexed flow for LPA and RPAwere evaluated. The growth rate of LPA was observed to be lower than that of RPA [percentage diameter increase: 74% vs 153%]. LPA Z score was lower than RPA. Indexed flow in both LPA and RPA showed a reduction in the 6-month scan, which was consistent with reduced stent patency.\u0000 \u0000 \u0000 \u0000 4D flow cardiac MRI showed different growth rates and reduced flow between LPA and RPA post-PDA stent. These insights can aid in future management decisions.\u0000","PeriodicalId":508944,"journal":{"name":"European Heart Journal - Imaging Methods and Practice","volume":"81 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140978648","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The effect of tube voltage on Scan-Rescan Reproducibility of compositional plaque volume: technical variability is not true biological change","authors":"F. Calicchio, Eric Hu, Shawn Newlander, Alexander van Rosendael, Elizabeth Epstein, Austin Robinson, Samantha R Spierling Bagsic, Jadranka Stojanovska, Jorge Gonzalez, G. Wesbey","doi":"10.1093/ehjimp/qyae041","DOIUrl":"https://doi.org/10.1093/ehjimp/qyae041","url":null,"abstract":"","PeriodicalId":508944,"journal":{"name":"European Heart Journal - Imaging Methods and Practice","volume":"71 9","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140984930","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Standardized Ketogenic Dietary Preparation for Metabolic PET Imaging in Suspected and Known Cardiac Sarcoidosis","authors":"E. Hutt, Ghazaleh Goldar, Wael A. Jaber, Paul C. Cremer","doi":"10.1093/ehjimp/qyae037","DOIUrl":"https://doi.org/10.1093/ehjimp/qyae037","url":null,"abstract":"\u0000 \u0000 \u0000 A major limitation of cardiac positron emission tomography (PET) with F18-fluorodeoxyglucose (F18-FDG) for the evaluation of cardiac sarcoidosis (CS) is associated with physiologic myocardial glucose uptake. The optimal dietary protocol to suppress physiologic myocardial F18-FDG uptake is not well-established. We aimed to evaluate the diagnostic performance of a novel dietary preparation using a ketone-based infant formula.\u0000 \u0000 \u0000 \u0000 Between 2018 and 2021, consecutive studies using a ketogenic dietary preparation were identified (n=198). The rate of non-diagnostic studies due to failure to suppress myocardial glucose was 7.1% (n= 14) with a similar incidence in diabetics (n= 6, 8.1%). Among studies reported to have no inflammation (N= 137), 130 studies (66%) had mean myocardial SUV less than or equal to mean blood pool SUV.\u0000 \u0000 \u0000 \u0000 Patient preparation with a ketone-based infant formula resulted in low rate of inappropriate myocardial glucose suppression in patients undergoing F18-FDG cardiac PET to evaluate cardiac sarcoidosis.\u0000","PeriodicalId":508944,"journal":{"name":"European Heart Journal - Imaging Methods and Practice","volume":" 32","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140996267","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Beware the glowing fat: pericarditis pitfall","authors":"A. Vaz","doi":"10.1093/ehjimp/qyae036","DOIUrl":"https://doi.org/10.1093/ehjimp/qyae036","url":null,"abstract":"","PeriodicalId":508944,"journal":{"name":"European Heart Journal - Imaging Methods and Practice","volume":" 42","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140996482","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Combined low dose dobutamine and exercise stress echocardiography: a new hybrid protocol to detect inducible ischaemia","authors":"Konstantinos Vakalis, Max Berrill, Majimen Jimeno, Ruth Chester, Shelley Rahman-Haley, Anthony Barron, A. Baltabaeva","doi":"10.1093/ehjimp/qyae038","DOIUrl":"https://doi.org/10.1093/ehjimp/qyae038","url":null,"abstract":"\u0000 \u0000 \u0000 Myocardial response to stress echocardiography may be elicited physiologically, through exercise, or pharmacologically, often with dobutamine. Both have advantages but also limitations due to reduced exercise capacity or side-effects to stressor agent/lack of closeness to true pathophysiology of ischaemic cascade. We have combined low-dose dobutamine and exercise, creating a “hybrid” protocol to utilise the advantages of both techniques and limit the drawbacks. The aim of the study was to evaluate its safety and feasibility.\u0000 \u0000 \u0000 \u0000 In the hybrid protocol low dose dobutamine infusion (up to 10 mcg/kg/min) is enhanced by supine bicycle exercise at 3 min increments of workload of 25W to achieve target heart rate. We analysed safety and outcome data for all patients who underwent this protocol from 2017-2022.\u0000 \u0000 \u0000 \u0000 727/835 (87.1%) patients referred for evaluation of ischaemia underwent the hybrid protocol. The median age was 61 years old and 61% (442/727) were men. The median exercise time was 11 (9-13.5) minutes with a median maximum workload of 100W (75-125). 670/727 (92.2%) achieved target heart rate. Atropine was not used. 192/727 (26.4%) of studies were positive for ischaemia. 102/122 (83.6%) with positive stress who underwent invasive angiography had significant coronary disease. The incidence of complications was low: 1/727 - severe arrhythmia, 5/727 (0.7%) developed a vasovagal episode and 14/727 (1.9%) had a hypertensive response to exercise.\u0000 \u0000 \u0000 \u0000 Our findings suggest that this protocol is safe, feasible and has a high success rate in achieving target heart rate.\u0000","PeriodicalId":508944,"journal":{"name":"European Heart Journal - Imaging Methods and Practice","volume":"90 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141004094","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"AI-QCT, CT-FFR, and physician visual interpretation in the per-vessel prediction of abnormal invasive adenosine FFR","authors":"Andrew Chiou, M. Hermel, Rajbir Sidhu, Eric Hu, Alexander van Rosendael, Samantha Bagsic, E. Udoh, Ricardo Kosturakis, Mohammad Aziz, Christina Rodriguez Ruiz, Shawn Newlander, Bahram Khadivi, Jason Parker Brown, M. L. Charlat, P. Teirstein, C. Stinis, Richard Schatz, Matthew J. Price, Jeffrey Cavendish, Michael Salerno, Austin Robinson, Sanjeev P Bhavnani, Jorge Gonzalez, G. Wesbey","doi":"10.1093/ehjimp/qyae035","DOIUrl":"https://doi.org/10.1093/ehjimp/qyae035","url":null,"abstract":"\u0000 \u0000 \u0000 A comparison of diagnostic performance comparing AI-QCTISCHEMIA, CT-FFR, and physician visual interpretation on the prediction of invasive adenosine FFR have not been evaluated. Furthermore, the coronary plaque characteristics impacting these tests have not been assessed.\u0000 \u0000 \u0000 \u0000 In a single center, 43-month retrospective review of 442 patients referred for CCTA and CT-FFR, 44 patients with CT-FFR had 54 vessels assessed using intracoronary adenosine FFR within 60 days. A comparison of the diagnostic performance among these three techniques for the prediction of FFR ≤ 0.80 was reported.\u0000 \u0000 \u0000 \u0000 The mean age of the study population was 65 years, 76.9% were male, and the median CAC was 623. When analyzing the per vessel ischemia prediction, AI-QCTISCHEMIA had greater specificity, PPV, diagnostic accuracy, and AUC vs. CT- FFR and physician visual interpretation CAD-RADS. The AUC for AI-QCTISCHEMIA was 0.91 vs. 0.76 for CT-FFR and 0.62 for CADRADS ≥3. Plaque characteristics that were different in false positive vs true positive cases for AI-QCTISCHEMIA was max stenosis diameter (50 vs 70%, p = 0.03); for CT-FFR were maximum stenosis diameter (40 vs 70%, p < 0.001), total noncalcified plaque (9 vs 13%, p = 0.02); and for physician visual interpretation CADRADS ≥3 were total noncalcified plaque (8 vs 12%, p = 0.01), lumen volume (681 vs 510mm3, p = 0.03), maximum stenosis diameter (40 vs 60%, p < 0.001), total plaque (19 vs 33%, p = 0.006, total calcified plaque (11 vs 22%, p = 0.008).\u0000 \u0000 \u0000 \u0000 Regarding per-vessel prediction of FFR ≤ 0.8, AI-QCTISCHEMIA revealed greater specificity, PPV, accuracy, and AUC vs. CT-FFR and physician visual interpretation CADRADS ≥3.\u0000","PeriodicalId":508944,"journal":{"name":"European Heart Journal - Imaging Methods and Practice","volume":"22 S8","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141010952","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}