{"title":"Age- and dose-independent adverse effect of venlafaxine-extended release on blood pressure: a case series of 13 normotensive psychiatric outpatients","authors":"M. Khosravi","doi":"10.4081/itjm.2024.1758","DOIUrl":"https://doi.org/10.4081/itjm.2024.1758","url":null,"abstract":"Dear Editor, the first antidepressant medication of the serotonin-norepinephrine reuptake inhibitor class is venlafaxine (effexor), which is taken orally with a half-life of 5 hours; however, its effective and chief metabolite (i.e., O-desmethylvenlafaxine) owns a half-life of 11 hours. [...]","PeriodicalId":508241,"journal":{"name":"Italian Journal of Medicine","volume":"84 7","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141662883","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"La sfida della prevenzione in medicina interna: a call for action","authors":"Francesco Dentali, Sara Rotunno","doi":"10.4081/itjm.q.2024.4","DOIUrl":"https://doi.org/10.4081/itjm.q.2024.4","url":null,"abstract":"\u0000Presentazione. La prevenzione è curaF. Dentali, S. Rotunno\u0000La comunicazione del rischio in prevenzione primaria, secondaria e terziariaG. Pinna\u0000Perché gli internisti ospedalieri si devono occupare di prevenzione?L. Lenzi, E. Schiavetta\u0000L’aspettativa di vita in Italia: cosa sta cambiando e perchéA. Grasso, F. Tangianu\u0000Il ruolo dell’infermiere nella prevenzione delle malattie cronicheL. Tesei, E. Perri, M. Accogli\u0000Focus: le carte del rischio cardiovascolare sono adeguate per i nostri pazienti?R. Calarco, G. Vurchio, D. Carrara\u0000Sindrome metabolica: quali strategie?G. Fontana, D. Romanello\u0000Il prediabete: l’iperglicemia intermedia può diventare un fattore preventivo di patologia?T.M. Attardo, L. Fontanella, V. Della Chiara\u0000Obesità e dislipidemia: una liaison non sempre obbligataF. Lorenzi, G.M. Pontesilli\u0000Malattia epatica associata a disfunzione metabolica e steatoepatite associata a disfunzione metabolica: possibile prevenzione dei fattori di rischioM. Spadaro, A.F.M. Vainieri\u0000Sigarette elettroniche e patologie respiratorie croniche: cosa sappiamo e cosa dovremmo sapereO. Para, G. Cassataro, A. Puggioni\u0000Scompenso cardiaco. Possibile parlare di prevenzione?N. Tarquinio, M.G. Coppola\u0000Prevenzione di genere: focus sulle malattie cardiacheT. Ciarambino, D. Addesi, P. Crispino\u0000Dieta mediterranea e prevenzione cardiovascolareM. Guadagni, E. Panizon, C. Tieri\u0000Interventi di prevenzione nelle malattie muscolo-scheletricheA. Migliore, N. Iannarelli, U. Massafra\u0000Attività fisica: come, quando e perchéR. Buso, A. Abenante, C. Nardin, L. Tonon\u0000Malattie infettive, scenari antichi, nuove emergenze: la vaccinazione nella popolazione generale e nel paziente complessoE. Pistella, M. Nardi\u0000Le buone regole di prevenzione FADOI: quando la prevenzione è curaO. Para, L. Lenzi, M. Guadagni, T. Ciarambino, M.G. Coppola, S. Rotunno, P. Gnerre","PeriodicalId":508241,"journal":{"name":"Italian Journal of Medicine","volume":"17 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141664886","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Nguyen Minh An, Ngo Trung Kiên, Nguyen Van Duc, Vo Hoang Long
{"title":"Retroperitoneal laparoscopic radical nephrectomy in the treatment of renal cancer: a 5-year single-center experience in resource-scare setting","authors":"Nguyen Minh An, Ngo Trung Kiên, Nguyen Van Duc, Vo Hoang Long","doi":"10.4081/itjm.2024.1764","DOIUrl":"https://doi.org/10.4081/itjm.2024.1764","url":null,"abstract":"Based on a retrospective hospital-based analysis, this study examines the results of retroperitoneal laparoscopic radical nephrectomy for patients with T1-T2 renal cell carcinoma (RCC) from January 2019 to December 2023. Of the 73 patients, 4.1% had TNM stage II tumors and 95.8% had TNM stage I tumors (53.4% T1a and 42.4% T1b). In terms of frequency, clear cell RCC accounted for 84.9%, with papillary RCC coming in at 9.6% and chromophobe RCC at 4.1%. Following surgery, four patients experienced fevers, one needed a blood transfusion, two had infections, and one had emergency surgery. Lumbar masses and hematuria were absent in all patients. Subsequent metastatic lesions and abnormalities of the renal fossa were not observed on follow-up ultrasounds. 4.1% of the deaths after 25.9 months were due to the disease, and 1.4% were caused by accidents. At one, two, three, and four years, the cumulative survival rates were 100%, 97.2%, and 92.8%, respectively. 48.1 months was the mean postoperative survival period. For RCC stages T1-2, retroperitoneal laparoscopic radical nephrectomy offers significant benefits and comparable results to open surgery.","PeriodicalId":508241,"journal":{"name":"Italian Journal of Medicine","volume":"116 16","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141666684","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
P. Pisanu, Nicolò Contu, Cristiana Picciau, Stefano Milighetti, Emiliano Deiana, Valeria Vannucci, Benedetta Centonze, Sara Pirastru, Sinai Del Carmen Fabriani Sanchez, Dario Lucchetti
{"title":"The importance of cognitive intervention in acquired traumatic brain injury during 6 months of multidisciplinary rehabilitation: a case description","authors":"P. Pisanu, Nicolò Contu, Cristiana Picciau, Stefano Milighetti, Emiliano Deiana, Valeria Vannucci, Benedetta Centonze, Sara Pirastru, Sinai Del Carmen Fabriani Sanchez, Dario Lucchetti","doi":"10.4081/itjm.2024.1763","DOIUrl":"https://doi.org/10.4081/itjm.2024.1763","url":null,"abstract":"Planning an immediate and multidisciplinary rehabilitation is crucial to reduce the significant physical, cognitive, and psychosocial impact resulting from head trauma. This study highlights the importance of ongoing cognitive rehabilitation in conjunction with other rehabilitation therapies, such as motor, occupational, and speech therapy, for a 19-year-old woman who suffered an acquired traumatic brain injury in a high-energy vehicle accident. When the patient was admitted to the hospital, their cognitive functioning (LCF) was 4 (confused-agitated state), their Barthel index was 0, their Glasgow coma scale (GCS) was 7, and their disability rating scale (DRS) was 7. The patient’s cognitive functioning improved to LCF 8 (purposeful-appropriate), numerical rating scale: 0/10, Barthel index: 53, GCS:15, and DRS: 5 at the time of discharge from the neurorehabilitation unit. In conclusion, early cognitive intervention in a multidisciplinary rehabilitation program is essential to maximizing the patient’s potential and improving the rehabilitation’s outcome.","PeriodicalId":508241,"journal":{"name":"Italian Journal of Medicine","volume":"123 47","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141667699","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Clelia Nasti, Raffaele Natale, Annadora Morena, Roberta Della Pepa, Fabrizio Pasanisi, L. Santarpia
{"title":"A rare case of multiple myeloma with several atypical manifestations","authors":"Clelia Nasti, Raffaele Natale, Annadora Morena, Roberta Della Pepa, Fabrizio Pasanisi, L. Santarpia","doi":"10.4081/itjm.2024.1760","DOIUrl":"https://doi.org/10.4081/itjm.2024.1760","url":null,"abstract":"A 75-year-old woman presented asthenia and anemia after recurrent intestinal bleeding. Colonoscopy showed the presence of blood clots in the ascending colon, without active bleeding. During hospitalization, right toe cyanosis progressed to ischemic necrosis and was resistant to analgesics and vasodilators. The positron emission tomography-computed tomography scan showed a nodular thickening in the midfield of the right lung. Blood chemistry evidenced an Immunoglobulin (Ig) G-λ monoclonal peak. Multiple myeloma (MM) was diagnosed by bone marrow biopsy and serum/urine Ig-free chain dosage. The patient no longer had intestinal bleeding after the first MM chemotherapy (CHT). After 6 months of CHT, a partial hematological response and peripheral vascular improvement occurred. Extremely rare conditions may result in MM. In this case report, seemingly unrelated atypical manifestations co-existed and responded to hematological CHT for MM, confirming their association with the disease.","PeriodicalId":508241,"journal":{"name":"Italian Journal of Medicine","volume":" 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141677525","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Dao Xuan Hai, P. M. Thong, Dong-Van He, L. Dung, Duong Duc Hung, Nguyen-Thi Huyen, Nguyen Minh Duc
{"title":"Outcomes of middle meningeal artery embolization for treating chronic subdural hematoma","authors":"Dao Xuan Hai, P. M. Thong, Dong-Van He, L. Dung, Duong Duc Hung, Nguyen-Thi Huyen, Nguyen Minh Duc","doi":"10.4081/itjm.2024.1759","DOIUrl":"https://doi.org/10.4081/itjm.2024.1759","url":null,"abstract":"The study evaluates chronic subdural hematoma (cSDH) middle meningeal artery (MMA) embolization efficacy and safety. A prospective interventional study was conducted in Viet Duc Hospital from November 2021 to April 2024. All consecutive cSDH MMA embolization patients were included. Clinical and imaging data were collected before and one month after treatment. The study included 31 42-cSDH patients. Of these, 25.8% had hematoma evacuation, 83.9% were treated with surgery and embolization, and 16.1% with embolization alone. 92.9% of procedures used polyvinyl alcohol particles. The success rate was 92.9% and complications 7.1%. Asymptomatic external carotid artery vasospasm and MMA rupture occurred. Functional improvement occurred in 91.7% of patients one month after treatment. Significantly lower mean modified Rankin Scale (mRS) score (0.2±0.7 vs. 1.7±0.9; P=0.000) and higher proportion of patients with ≤2 mRS score (95.8% vs. 74.1%) were observed after treatment. Hematoma thickness decreased significantly (P=0.00) from 21.5±7.9 mm to 8.3±4.1 mm. The midline shift decreased significantly from 7.4±5.0 mm to 0.7±1.2 mm (P=0.00). Just one patient (4.2%) needed surgery. MMA embolization alone or with surgery appears to treat cSDH safely and effectively.","PeriodicalId":508241,"journal":{"name":"Italian Journal of Medicine","volume":"217 S708","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141681560","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Area of admission and short-term care: is it still possible after the COVID pandemic?","authors":"Francesco Serafini, Elia Vettore, Fabio Presotto","doi":"10.4081/itjm.2024.1746","DOIUrl":"https://doi.org/10.4081/itjm.2024.1746","url":null,"abstract":"Dear Editor, Since 2011, the Internal Medical Unit of Ospedale dell’Angelo, Mestre, has been equipped with an area of eight beds which served as a short-stay unit called area di accoglimento e degenza breve (area of admission and short-term care, ADB). All patients coming from the emergency room (99%) passed through the ADB area. Here, doctors and nurses carried out an initial clinical care triage to identify patients with features that made the discharge possible within 72 hours. [...]","PeriodicalId":508241,"journal":{"name":"Italian Journal of Medicine","volume":"17 12","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-06-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141355818","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Roberta Panarelli, Cosima Caputo, Giovanna Cavino, Antonio Scarpa, Lucia Giordano, Pasquale Palmiero
{"title":"Primary prevention of cardiovascular diseases in the elderly population","authors":"Roberta Panarelli, Cosima Caputo, Giovanna Cavino, Antonio Scarpa, Lucia Giordano, Pasquale Palmiero","doi":"10.4081/itjm.2024.1730","DOIUrl":"https://doi.org/10.4081/itjm.2024.1730","url":null,"abstract":"The epidemic of chronic cardiovascular diseases must be managed and prevented. We examine if a sample of 65-75-yearolds knows and practices the right lifestyles to prevent chronic cardiovascular diseases, their habits and risk levels, and whether the paradigm of cardiovascular prevention needs to change. We recruited 153 men (50.2%) and 152 women (49.8%), aged 65- 70 for 55% and 71-75 for 45%. Most were overweight (38.2%), obese (28.2%), and normal (33.6%). 67.1% trusted to eat right, and only 20.6% always ate low-salt. 54.4% of our population considers their exercise sufficient, but 83% do not practice it, and 72.3% know the importance of daily exercise. 54.3% consider themselves healthy, but 51% have chronic diseases, including arterial hypertension (37.2%), diabetes (23.1%), heart failure (20.5%), and chronic obstructive bronchopathy (21.8%). Understanding the disease, its effects, and complications, and taking care of one’s health can help people live longer and prevent cardiovascular events.","PeriodicalId":508241,"journal":{"name":"Italian Journal of Medicine","volume":"4 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140963363","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Vittoria Gammaldi, Anna Guida, C. Bologna, Antonietta De Sena, M. Lugará, Claudio De Luca, Fabio Granato Corigliano, Mariavittoria Guerra, Gabriella Oliva, Luca Mocerino, A. Zarrella, Maria Gabriella Coppola, Vincenzo Nuzzo, Paolo Tirelli, P. Madonna
{"title":"Acquired hemophilia A in a case of purple urine bag syndrome","authors":"Vittoria Gammaldi, Anna Guida, C. Bologna, Antonietta De Sena, M. Lugará, Claudio De Luca, Fabio Granato Corigliano, Mariavittoria Guerra, Gabriella Oliva, Luca Mocerino, A. Zarrella, Maria Gabriella Coppola, Vincenzo Nuzzo, Paolo Tirelli, P. Madonna","doi":"10.4081/itjm.2024.1713","DOIUrl":"https://doi.org/10.4081/itjm.2024.1713","url":null,"abstract":"The rare hemorrhagic disorder known as acquired hemophilia A (AHA) is brought on by the spontaneous development of autoantibodies against coagulation factor VIII (FVIII). It may be secondary to autoimmune diseases or cancers, or it may be idiopathic. Less than 10% of cases may have an infection as a secondary cause. We present the case of a 90-year-old anemic woman who was admitted to the hospital. She contracted a urinary tract infection (UTI) while in the hospital, and her urine took on a distinct purple hue. She had poor hemorrhagic manifestations and a prolonged partial thromboplastin time. After ruling out autoimmune and neoplastic causes, we diagnosed AHA as a result of a UTI caused by Enterococcus faecalis.","PeriodicalId":508241,"journal":{"name":"Italian Journal of Medicine","volume":"16 23","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140966767","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
M. Moroni, Massimo Melo, Raffaella Antonione, Massimo Fantoni, Roberto Luzzati, Massimiliano Lanzafame, Rita Murri, Fabio Gilioli, Francesco Dentali, Dario Manfellotto, Biancamaria Fraccaro, Luigi Patil
{"title":"Uso degli antibiotici nel fine vita","authors":"M. Moroni, Massimo Melo, Raffaella Antonione, Massimo Fantoni, Roberto Luzzati, Massimiliano Lanzafame, Rita Murri, Fabio Gilioli, Francesco Dentali, Dario Manfellotto, Biancamaria Fraccaro, Luigi Patil","doi":"10.4081/itjm.q.2024.3","DOIUrl":"https://doi.org/10.4081/itjm.q.2024.3","url":null,"abstract":"\u0000Introduzione \u0000Survey intersocietaria SICP-SIMIT-FADOI-SIMG \u0000La febbre in un contesto clinico di fine vita \u0000Peculiarità dei principali setting di cura \u0000Principali quadri sindromici nei pazienti a fine vita e indicazioni terapeutiche \u0000Antibiotici in infusione continua endovena o per via sottocutanea \u0000Bibliografia","PeriodicalId":508241,"journal":{"name":"Italian Journal of Medicine","volume":"34 11","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140968809","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}