Vittoria Gammaldi, Anna Guida, C. Bologna, Antonietta De Sena, M. Lugará, Claudio De Luca, Fabio Granato Corigliano, Mariavittoria Guerra, Gabriella Oliva, Luca Mocerino, A. Zarrella, Maria Gabriella Coppola, Vincenzo Nuzzo, Paolo Tirelli, P. Madonna
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引用次数: 0
摘要
获得性血友病 A（AHA）是一种罕见的出血性疾病，是由针对凝血因子 VIII（FVIII）的自身抗体自发形成的。它可能继发于自身免疫性疾病或癌症，也可能是特发性的。不到 10%的病例可能继发于感染。我们为您介绍一例入院的 90 岁贫血妇女的病例。她在住院期间感染了尿路感染（UTI），尿液呈明显的紫色。她的出血性表现不佳，部分凝血活酶时间延长。在排除了自身免疫性疾病和肿瘤性疾病的病因后，我们诊断出 AHA 是由粪肠球菌引起的尿路感染所致。
Acquired hemophilia A in a case of purple urine bag syndrome
The rare hemorrhagic disorder known as acquired hemophilia A (AHA) is brought on by the spontaneous development of autoantibodies against coagulation factor VIII (FVIII). It may be secondary to autoimmune diseases or cancers, or it may be idiopathic. Less than 10% of cases may have an infection as a secondary cause. We present the case of a 90-year-old anemic woman who was admitted to the hospital. She contracted a urinary tract infection (UTI) while in the hospital, and her urine took on a distinct purple hue. She had poor hemorrhagic manifestations and a prolonged partial thromboplastin time. After ruling out autoimmune and neoplastic causes, we diagnosed AHA as a result of a UTI caused by Enterococcus faecalis.
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