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Herpes zoster after ground-level fall. 从地面坠落后出现带状疱疹。
IF 5.3 3区 医学
American Journal of Medicine Pub Date : 2025-08-12 DOI: 10.1016/j.amjmed.2025.07.042
Ami Schattner
{"title":"Herpes zoster after ground-level fall.","authors":"Ami Schattner","doi":"10.1016/j.amjmed.2025.07.042","DOIUrl":"10.1016/j.amjmed.2025.07.042","url":null,"abstract":"","PeriodicalId":50807,"journal":{"name":"American Journal of Medicine","volume":" ","pages":""},"PeriodicalIF":5.3,"publicationDate":"2025-08-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144856915","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Sodium Glucose Co-Transporter-2 inhibitors in patients with systemic sclerosis with or without heart failure. 钠葡萄糖共转运蛋白-2抑制剂在伴有或不伴有心力衰竭的系统性硬化症患者中的应用
IF 5.3 3区 医学
American Journal of Medicine Pub Date : 2025-08-12 DOI: 10.1016/j.amjmed.2025.08.009
Silvio Nunes Augusto, David C Kaelber, Soumya Chatterjee, W H Wilson Tang
{"title":"Sodium Glucose Co-Transporter-2 inhibitors in patients with systemic sclerosis with or without heart failure.","authors":"Silvio Nunes Augusto, David C Kaelber, Soumya Chatterjee, W H Wilson Tang","doi":"10.1016/j.amjmed.2025.08.009","DOIUrl":"10.1016/j.amjmed.2025.08.009","url":null,"abstract":"<p><strong>Background: </strong>Patients with systemic sclerosis are at heightened risk of developing heart failure. Sodium-glucose cotransporter 2 inhibitors (SGLT2i) have shown cardio-renal benefits in diverse populations with cardio-renal dysfunction, but their impact on outcomes in patients with systemic sclerosis has not been described.</p><p><strong>Methods: </strong>This retrospective cohort study used the Research Network of the TriNetX platform to compare outcomes between patients with systemic sclerosis prescribed with SGLT2 inhibitors versus those without SGLT2i prescription, using data from January 1, 2013, to May 6, 2025. Following propensity score matching, each cohort included 1,402 patients with balanced baseline characteristics (standardized mean differences <0.2). The primary outcome was all-cause mortality. Secondary outcomes included first-time heart failure diagnosis, acute heart failure, acute myocardial infarction, hospitalization, stroke, cardiac arrest, and chronic kidney disease.</p><p><strong>Results: </strong>SGLT2i prescription was associated with a significantly lower risk of all-cause mortality (Hazard Ratio [HR] 0.54, 95 % confidence interval [CI] 0.44-0.66), stroke (HR 0.64, 95 % CI 0.42-0.96), and hospitalization (HR 0.76, 95 % CI 0.66-0.86). Notably, patients without a history of heart failure (HR 0.62, 95 % CI 0.45-0.87) and patients with a history of heart failure also had a lower risk of hospitalization (HR 0.76, 95 % CI 0.57-1.00). No significant differences were observed in the risks of major adverse cardiovascular events, acute myocardial infarction, or chronic kidney disease.</p><p><strong>Conclusion: </strong>In this real-world analysis, SGLT2 inhibitors were associated with reduced mortality, stroke, and hospitalization in patients with systemic sclerosis, supporting their potential therapeutic role in this population.</p>","PeriodicalId":50807,"journal":{"name":"American Journal of Medicine","volume":" ","pages":""},"PeriodicalIF":5.3,"publicationDate":"2025-08-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144856917","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The wisdom of medical aphorisms, part 1. 医学格言的智慧，第一部分。
IF 5.3 3区 医学
American Journal of Medicine Pub Date : 2025-08-07 DOI: 10.1016/j.amjmed.2025.08.001
Joseph S Alpert
{"title":"The wisdom of medical aphorisms, part 1.","authors":"Joseph S Alpert","doi":"10.1016/j.amjmed.2025.08.001","DOIUrl":"10.1016/j.amjmed.2025.08.001","url":null,"abstract":"","PeriodicalId":50807,"journal":{"name":"American Journal of Medicine","volume":" ","pages":""},"PeriodicalIF":5.3,"publicationDate":"2025-08-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144785885","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The wisdom of medical aphorisms, Part 2. 医学格言的智慧，第二部分。
IF 5.3 3区 医学
American Journal of Medicine Pub Date : 2025-08-06 DOI: 10.1016/j.amjmed.2025.08.002
Joseph S Alpert
{"title":"The wisdom of medical aphorisms, Part 2.","authors":"Joseph S Alpert","doi":"10.1016/j.amjmed.2025.08.002","DOIUrl":"10.1016/j.amjmed.2025.08.002","url":null,"abstract":"","PeriodicalId":50807,"journal":{"name":"American Journal of Medicine","volume":" ","pages":""},"PeriodicalIF":5.3,"publicationDate":"2025-08-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144805237","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A combination drug pill used for first line therapy of systemic hypertension. 一种用于全身性高血压一线治疗的复方药物。
IF 5.3 3区 医学
American Journal of Medicine Pub Date : 2025-08-05 DOI: 10.1016/j.amjmed.2025.07.021
William H Frishman, Wilbert S Aronow, Joseph S Alpert
{"title":"A combination drug pill used for first line therapy of systemic hypertension.","authors":"William H Frishman, Wilbert S Aronow, Joseph S Alpert","doi":"10.1016/j.amjmed.2025.07.021","DOIUrl":"10.1016/j.amjmed.2025.07.021","url":null,"abstract":"","PeriodicalId":50807,"journal":{"name":"American Journal of Medicine","volume":" ","pages":""},"PeriodicalIF":5.3,"publicationDate":"2025-08-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144785882","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
E2DUCATE: A blueprint for institutions and societies to elevate faculty development for clinician educators. e2educate：机构与社团提升临床医师教育师资发展的蓝图。
IF 5.3 3区 医学
American Journal of Medicine Pub Date : 2025-08-05 DOI: 10.1016/j.amjmed.2025.07.035
Amna Anees, Craig Noronha, Karen A Friedman, Aashish Didwania
{"title":"E<sup>2</sup>DUCATE: A blueprint for institutions and societies to elevate faculty development for clinician educators.","authors":"Amna Anees, Craig Noronha, Karen A Friedman, Aashish Didwania","doi":"10.1016/j.amjmed.2025.07.035","DOIUrl":"10.1016/j.amjmed.2025.07.035","url":null,"abstract":"","PeriodicalId":50807,"journal":{"name":"American Journal of Medicine","volume":" ","pages":""},"PeriodicalIF":5.3,"publicationDate":"2025-08-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144790598","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Biological disease-modifying agents transform rheumatology treatment. 生物疾病修饰剂改变风湿病治疗。
IF 5.3 3区 医学
American Journal of Medicine Pub Date : 2025-08-05 DOI: 10.1016/j.amjmed.2025.07.025
Edward J Goetzl
{"title":"Biological disease-modifying agents transform rheumatology treatment.","authors":"Edward J Goetzl","doi":"10.1016/j.amjmed.2025.07.025","DOIUrl":"10.1016/j.amjmed.2025.07.025","url":null,"abstract":"","PeriodicalId":50807,"journal":{"name":"American Journal of Medicine","volume":" ","pages":""},"PeriodicalIF":5.3,"publicationDate":"2025-08-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144785883","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Syncope: The oldest, yet the faintest tale - A call for a new definition. 晕厥：最古老，但最微弱的故事-呼吁一个新的定义。
IF 5.3 3区 医学
American Journal of Medicine Pub Date : 2025-08-05 DOI: 10.1016/j.amjmed.2025.07.026
Giuseppe Magro
{"title":"Syncope: The oldest, yet the faintest tale - A call for a new definition.","authors":"Giuseppe Magro","doi":"10.1016/j.amjmed.2025.07.026","DOIUrl":"10.1016/j.amjmed.2025.07.026","url":null,"abstract":"","PeriodicalId":50807,"journal":{"name":"American Journal of Medicine","volume":" ","pages":""},"PeriodicalIF":5.3,"publicationDate":"2025-08-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144776815","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Symptomatic innominate vein aneurysm presenting as cyclic upper extremity edema. 症状性无名静脉动脉瘤表现为上肢循环水肿。
IF 5.3 3区 医学
American Journal of Medicine Pub Date : 2025-08-05 DOI: 10.1016/j.amjmed.2025.07.023
C A Jiménez-Echandía, J D Arguello, A C Montenegro
{"title":"Symptomatic innominate vein aneurysm presenting as cyclic upper extremity edema.","authors":"C A Jiménez-Echandía, J D Arguello, A C Montenegro","doi":"10.1016/j.amjmed.2025.07.023","DOIUrl":"10.1016/j.amjmed.2025.07.023","url":null,"abstract":"","PeriodicalId":50807,"journal":{"name":"American Journal of Medicine","volume":" ","pages":""},"PeriodicalIF":5.3,"publicationDate":"2025-08-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144769258","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Mind the gap. 注意缝隙。
IF 5.3 3区 医学
American Journal of Medicine Pub Date : 2025-08-05 DOI: 10.1016/j.amjmed.2025.07.030
Laszlo Littmann
{"title":"Mind the gap.","authors":"Laszlo Littmann","doi":"10.1016/j.amjmed.2025.07.030","DOIUrl":"10.1016/j.amjmed.2025.07.030","url":null,"abstract":"","PeriodicalId":50807,"journal":{"name":"American Journal of Medicine","volume":" ","pages":""},"PeriodicalIF":5.3,"publicationDate":"2025-08-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144785884","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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