American Journal of Medicine最新文献

{"title":"Retraction notice to ‘Homocysteine as A Predictive Factor for Hip Fracture in Elderly Women With Parkinson’s Disease’ [The American Journal of Medicine 118 (2005) 1250-1255]","authors":"Yoshihiro Sato MD , Jun Iwamoto MD , Tomohiro Kanoko PhD , Kei Satoh MD","doi":"10.1016/j.amjmed.2025.04.029","DOIUrl":"10.1016/j.amjmed.2025.04.029","url":null,"abstract":"","PeriodicalId":50807,"journal":{"name":"American Journal of Medicine","volume":"138 6","pages":"Page 1046"},"PeriodicalIF":2.5,"publicationDate":"2025-05-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144071859","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Spectrum of Long-COVID Symptoms Should Be Assessed Through On-Site Examinations Rather Than Electronic Questionnaires","authors":"Josef Finsterer MD, PhD","doi":"10.1016/j.amjmed.2024.06.017","DOIUrl":"10.1016/j.amjmed.2024.06.017","url":null,"abstract":"","PeriodicalId":50807,"journal":{"name":"American Journal of Medicine","volume":"138 6","pages":"Page e119"},"PeriodicalIF":2.5,"publicationDate":"2025-05-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144072222","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Reply","authors":"Nilihan E.M. Sanal-Hayes PhD , Marie Mclaughlin PhD , Lawrence D. Hayes PhD , Ethan C.J. Berry BSc (Hons) , Nicholas F. Sculthorpe PhD","doi":"10.1016/j.amjmed.2024.07.021","DOIUrl":"10.1016/j.amjmed.2024.07.021","url":null,"abstract":"","PeriodicalId":50807,"journal":{"name":"American Journal of Medicine","volume":"138 6","pages":"Pages e120-e121"},"PeriodicalIF":2.5,"publicationDate":"2025-05-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144072223","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Retraction notice to ‘A Four-Year Randomized Controlled Trial of Hormone Replacement and Bisphosphonate, Alone or in Combination, in Women with Postmenopausal Osteoporosis’ [The American Journal of Medicine 104 (1998) 219-226]","authors":"Sunil J. Wimalawansa MD, PhD","doi":"10.1016/j.amjmed.2025.03.012","DOIUrl":"10.1016/j.amjmed.2025.03.012","url":null,"abstract":"","PeriodicalId":50807,"journal":{"name":"American Journal of Medicine","volume":"138 6","pages":"Page 1044"},"PeriodicalIF":2.5,"publicationDate":"2025-05-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144071943","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"National Strategies to Reduce Violence Against Health Care Workers.","authors":"Wasan M Kumar, Eli Y Adashi","doi":"10.1016/j.amjmed.2025.05.006","DOIUrl":"10.1016/j.amjmed.2025.05.006","url":null,"abstract":"","PeriodicalId":50807,"journal":{"name":"American Journal of Medicine","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2025-05-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144059871","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Emphysematous Hepatitis and Septic Pylephlebitis Caused by Gram Negative Bacteremia.","authors":"Eleftheria Paida, Georgios Sapouridis, Erieta Karypidou, Elisavet Simoulidou, Aristeidis Kefas, Sofia Chatzimichailidou, Spyros Papadopoulos, Charalampos Zarras, Anastasia Sarvani, Georgios Damianidis, Konstantinos Petidis, Michail Doumas, Athina Pyrpasopoulou","doi":"10.1016/j.amjmed.2025.05.009","DOIUrl":"10.1016/j.amjmed.2025.05.009","url":null,"abstract":"","PeriodicalId":50807,"journal":{"name":"American Journal of Medicine","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2025-05-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144031286","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cardiac Sarcoidosis Presenting with High-Grade Atrioventricular Block: The Importance of Multimodality Imaging.","authors":"Jacob Ref, Natasha Khona, Amitoj Singh, Julia H Indik, Kwan S Lee, Tushar Acharya, Iniya Rajendran","doi":"10.1016/j.amjmed.2025.05.007","DOIUrl":"10.1016/j.amjmed.2025.05.007","url":null,"abstract":"","PeriodicalId":50807,"journal":{"name":"American Journal of Medicine","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2025-05-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144042836","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Syphilitic Orchitis.","authors":"Shunsuke Ohara, Taiju Miyagami, Arisa Ito, Toshio Naito","doi":"10.1016/j.amjmed.2025.05.005","DOIUrl":"10.1016/j.amjmed.2025.05.005","url":null,"abstract":"","PeriodicalId":50807,"journal":{"name":"American Journal of Medicine","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2025-05-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144044193","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Beta-Blockers and Outcome in Patients with Suspected Coronary Artery Disease Evaluated Noninvasively.","authors":"Yu Kang, Zhuoran Zhao, Zixuan Yang, Leyi Zeng, Nan Qu, Qing Zhang, Wanxiang Jiang, Jiafu Wei","doi":"10.1016/j.amjmed.2025.04.019","DOIUrl":"10.1016/j.amjmed.2025.04.019","url":null,"abstract":"<p><strong>Objective: </strong>Our intent was to assess the relationship between beta-blocker use and outcomes in patients with chronic coronary artery disease diagnosed using noninvasive testing but without myocardial infarction or heart failure.</p><p><strong>Methods: </strong>Data from the Prospective Multicenter Imaging Study for Evaluation of Chest Pain (PROMISE) study, a prospective randomized trial comparing the effectiveness of 2 noninvasive tests in patients with a low-to-intermediate likelihood of coronary artery disease, were subjected to post hoc analysis. Patients with a history of myocardial infarction or heart failure and those with missing data on beta-blocker use at baseline were excluded. Associations between baseline beta-blocker use and the primary composite outcome (all-cause death / myocardial infarction / unstable angina hospitalization) and secondary composite outcomes (cardiovascular death / myocardial infarction / unstable angina hospitalization, and myocardial infarction / unstable angina hospitalization) over a median follow-up period of 793 days were analyzed.</p><p><strong>Results: </strong>In total, 8,250 patients were enrolled and stratified into negative (87.5%, n = 7,215) and positive (12.5%, n = 1,035) cohorts based on noninvasive test results, of which 23.9% and 28.6% received beta-blockers, respectively. In both cohorts, patients who received beta-blockers had a similar risk of the primary composite outcome compared to those who did not receive beta-blockers (negative cohort: adjusted hazard ratio = 1.106, P = .586; positive cohort: adjusted hazard ratio = 1.077, P = .759). Similar results were observed for the secondary composite outcomes.</p><p><strong>Conclusions: </strong>This non-randomized study showed that beta-blocker use did not affect the clinical outcomes in patients with chronic coronary artery disease diagnosed using noninvasive testing, if they had no myocardial infarction or heart failure.</p>","PeriodicalId":50807,"journal":{"name":"American Journal of Medicine","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2025-05-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143994621","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Renin Angiotensin Inhibition and Lower Risk of Kidney Failure in Patients with Heart Failure.","authors":"Samir S Patel, Venkatesh K Raman, Sijian Zhang, Helen M Sheriff, Gregg C Fonarow, Paul A Heidenreich, Charles Faselis, Phillip H Lam, Charity J Morgan, Hans Moore, David Atkins, Yan Cheng, Yijun Shao, Prakash Deedwania, Carlos E Palant, Brian C Sauer, Ravindra L Mehta, Thomas E Love, Richard M Allman, Michael S Heimall, Wen-Chih Wu, Qing Zeng-Treitler, Ali Ahmed","doi":"10.1016/j.amjmed.2025.04.038","DOIUrl":"10.1016/j.amjmed.2025.04.038","url":null,"abstract":"<p><strong>Background: </strong>Renin-angiotensin system (RAS) inhibitors reduce risk of kidney failure in patients with chronic kidney disease, but worsen kidney function in heart failure patients, especially in those with chronic kidney disease. Less is known about risk of kidney failure in heart failure patients receiving RAS inhibitors.</p><p><strong>Methods: </strong>We used propensity score matching for outcome-blinded assembly of 168,860 Veterans with heart failure phenotyped by artificial intelligence who were balanced on 77 baseline characteristics and initiated on RAS inhibitors. Hazard ratio (95% confidence interval [CI]) for 5-year kidney failure in high-dose (vs low-dose) RAS inhibitor group was estimated, accounting for competing risk of death. Kidney failure was defined as kidney replacement therapy or estimated glomerular filtration rate (eGFR) rate <15 mL/min/1.73 m².</p><p><strong>Results: </strong>New-onset kidney failure occurred in 4.1% (3455/84,430) and 3.5% (2966/84,430) of patients in low-dose and high-dose RAS inhibitor groups, respectively (hazard ratio, 0.85; 95% CI, 0.81-0.89). Respective hazard ratios (95% CIs) in eGFR rate subgroups ≥60, 45-59, and 15-44 mL/min/1.73 m² were 1.21 (1.08-1.36), 0.93 (0.82-1.05), and 0.82 (0.77-0.87). The association was similar across ejection fraction subgroups. There was a lower risk of death in the subgroup with ejection fraction ≤40%.</p><p><strong>Conclusions: </strong>Patients with heart failure receiving high-dose (vs low-dose) RAS inhibitors had a lower associated risk of kidney failure, which was driven by the subgroup with chronic kidney disease. This new information may help to inform future guideline recommendations and clinical practice regarding RAS inhibitor use in these patients. Future studies need to examine this association in those with normal kidney function.</p>","PeriodicalId":50807,"journal":{"name":"American Journal of Medicine","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2025-05-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144037991","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}