{"title":"Masked central nervous system infection from a paraplegic's pressure ulcer.","authors":"Tetsuya Oyama, Hirotaka Nakanishi","doi":"10.1016/j.amjmed.2025.07.043","DOIUrl":"10.1016/j.amjmed.2025.07.043","url":null,"abstract":"","PeriodicalId":50807,"journal":{"name":"American Journal of Medicine","volume":" ","pages":""},"PeriodicalIF":5.3,"publicationDate":"2025-08-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144859875","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"An Approach to the Older Patient with a Suspicion of HFpEF.","authors":"Daniel M Gelfman","doi":"10.1016/j.amjmed.2025.07.036","DOIUrl":"10.1016/j.amjmed.2025.07.036","url":null,"abstract":"<p><p>It is not uncommon to see older patients who have dyspnea limiting exercise tolerance and a non-diagnostic H2FPEF score, but with an estimated probability of HFpEF of 55-75%. These patients often have dependent edema or hypertension. Frequently we, and the patients themselves, believe their symptoms are due to age, obesity, and deconditioning; however, recent data is suggesting the presence of HFpEF. Even without HFpEF, they are at high risk of developing it over time. There is reluctance in proceeding with a hemodynamic stress test, as it is not readily available and invasive. Both dyspnea on exertion and dependent peripheral edema are sensitive but not specific for HFpEF. Treatment with diuretics does decrease the incidence and recurrence of heart failure in patients with Stage B or C HFpEF. We treat patients with increased LDL cholesterol based on the risk of development of coronary artery disease. Using this same logic, patients with suspected but not proven HFpEF could benefit from the use of mild diuretics targeting peripheral edema or hypertension and ultimately targeting HFpEF or its development.</p>","PeriodicalId":50807,"journal":{"name":"American Journal of Medicine","volume":" ","pages":""},"PeriodicalIF":5.3,"publicationDate":"2025-08-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144859871","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Curious medical etymologies.","authors":"Pedro Gargantilla Madera","doi":"10.1016/j.amjmed.2025.08.004","DOIUrl":"10.1016/j.amjmed.2025.08.004","url":null,"abstract":"","PeriodicalId":50807,"journal":{"name":"American Journal of Medicine","volume":" ","pages":""},"PeriodicalIF":5.3,"publicationDate":"2025-08-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144859872","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sneha Rajeev, Maria G Santoyo Martinez, Joshua E Lane
{"title":"Metastatic breast adenocarcinoma.","authors":"Sneha Rajeev, Maria G Santoyo Martinez, Joshua E Lane","doi":"10.1016/j.amjmed.2025.07.038","DOIUrl":"10.1016/j.amjmed.2025.07.038","url":null,"abstract":"","PeriodicalId":50807,"journal":{"name":"American Journal of Medicine","volume":" ","pages":""},"PeriodicalIF":5.3,"publicationDate":"2025-08-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144859876","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Skye A McKennon, Ross J Bindler, Jennifer C Miller, Marian Wilson, Dawn E DeWitt
{"title":"Evaluating the impact of Apollo Neuro™ wearable on wellbeing in medical and pharmacy students: A preliminary prospective randomized controlled study.","authors":"Skye A McKennon, Ross J Bindler, Jennifer C Miller, Marian Wilson, Dawn E DeWitt","doi":"10.1016/j.amjmed.2025.07.045","DOIUrl":"10.1016/j.amjmed.2025.07.045","url":null,"abstract":"<p><strong>Purpose: </strong>Burnout affects up to 70% of US medical and pharmacy students, often accompanied by depression, anxiety, at-risk drinking, and suicidal ideation. While wellbeing interventions impacting mindfulness exist, they are often time- and cost-prohibitive. The Apollo Neuro™ (AN), a wearable device designed to regulate stress responses, may offer a low-burden alternative.</p><p><strong>Methods: </strong>This pilot study assessed AN's impact on stress and wellbeing among medical and pharmacy students. Sixty-six students were randomized 1:1 to either receive the device (Active group) or join a waitlist (Control). Participants completed surveys at baseline, 6-, and 12-weeks, including the Maslach Burnout Inventory (MBI-2), Medical Student Well-Being Index (MSWBI), Perceived Stress Scale, Brief Resilience Scale, and Alcohol Use Disorders Identification Test-C.</p><p><strong>Results: </strong>At 12 weeks, students using AN showed significant improvement in burnout (MBI-2 total, emotional exhaustion, depersonalization) and MSWBI scores compared to controls. No significant changes were seen in resilience or alcohol use.</p><p><strong>Conclusions: </strong>AN appears to be a feasible, efficacious tool for reducing burnout and improving wellbeing in health professional students, meriting further investigation.</p>","PeriodicalId":50807,"journal":{"name":"American Journal of Medicine","volume":" ","pages":""},"PeriodicalIF":5.3,"publicationDate":"2025-08-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144859873","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Yasasvhinie Santharam, Alexis Chrystman, Win M Aung
{"title":"Unprotected sex and unusual sepsis: Campylobacter bacteremia in AIDS.","authors":"Yasasvhinie Santharam, Alexis Chrystman, Win M Aung","doi":"10.1016/j.amjmed.2025.08.008","DOIUrl":"10.1016/j.amjmed.2025.08.008","url":null,"abstract":"","PeriodicalId":50807,"journal":{"name":"American Journal of Medicine","volume":" ","pages":""},"PeriodicalIF":5.3,"publicationDate":"2025-08-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144859877","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}