American Journal of Preventive Medicine最新文献

{"title":"Rural-Urban Differences in Suicide and Firearm-Related Suicide Deaths Across Geographic Regions in the United States.","authors":"Nora E Mertz-Bynum, Dylan J Bilicki, Ketan R N Brodeur, Kelly A Hirko","doi":"10.1016/j.amepre.2026.108394","DOIUrl":"https://doi.org/10.1016/j.amepre.2026.108394","url":null,"abstract":"<p><strong>Introduction: </strong>This study assessed differences in overall suicide and firearm-related suicide rates across urban and rural U.S. counties and explored variation by geographic region.</p><p><strong>Methods: </strong>An ecological cross-sectional analysis was conducted, using generalized linear models with negative binomial distribution and log link to estimate incidence rate differences (RD), rate ratios (IRR) with 95% confidence intervals, and the proportion of suicide deaths attributed to firearms across rural and urban U.S. counties, overall and by Census region. Data were obtained from the Centers for Disease Control and Prevention's Wide-ranging Online Data for Epidemiologic Research (WONDER) database (2015-2020) and analyzed between 2023 and 2025.</p><p><strong>Results: </strong>Between 2015 and 2020, there were 274,973 suicides, with 137,051 (49.7%) involving firearms. Suicide and firearm-related suicide rates increased with rurality, peaking in the most rural counties (31.2 and 24.5 per 100,000), though linear trends across the Rural-Urban Continuum Code were not significant (overall p_trend = 0.053; firearm-related p_trend = 0.115). Rural counties had higher suicide rates than urban counties (overall: RD = 3.4, IRR = 1.21, 95% CI: 1.18-1.25; firearm-related: RD = 3.4, IRR = 1.37, 95% CI: 1.33-1.42), with the largest disparities in the West and smallest in the South (all p_int < 0.0001). The proportion of suicides involving firearms increased with rurality overall (p_trend < 0.0001), with the magnitude of rural-urban differences varying across geographic regions (p_int<0.0001).</p><p><strong>Conclusions: </strong>Results demonstrate rural-urban disparities in suicide and firearm-related suicide rates with variation in magnitude across U.S geographic regions. These findings underscore the need for regionally tailored suicide prevention efforts in rural areas with higher firearm access and limited mental health services.</p>","PeriodicalId":50805,"journal":{"name":"American Journal of Preventive Medicine","volume":" ","pages":"108394"},"PeriodicalIF":4.5,"publicationDate":"2026-04-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147787983","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Nicotine Pouch Use Among U.S. Adults in 2023 and 2024.","authors":"Yi-Chun Chang, Megan E Patrick, Yvonne M Terry-McElrath, Junhan Cho, Richard A Miech, Adam M Leventhal","doi":"10.1016/j.amepre.2026.108393","DOIUrl":"https://doi.org/10.1016/j.amepre.2026.108393","url":null,"abstract":"<p><p>Introduction Recent expansion of U.S. nicotine pouch marketing may increase nicotine pouch use. This study estimated U.S. adult pouch use during 2023-2024 overall and across sociodemographic, cigarette smoking, nicotine vaping, and non-nicotine substance use subgroups. Methods Data were drawn from the nationally representative Monitoring the Future longitudinal panel 2023 and 2024 surveys (N=15,340; ages 19-65 years; 59.6% response rate conditional on wave 1; analyzed in 2025-2026). Past-12-month and past-30-day nicotine pouch use prevalences were estimated each year in the overall sample and stratified by sociodemographic and substance use statuses. Results In the overall sample, prevalence increased from 2023 to 2024 for past-12-month (3.4% to 5.9%; Prevalence Ratio [PR]=1.75, 95%CI=1.45-2.13) and past-30-day use (2.3% to 4.2%; PR=1.81, 95%CI=1.44-2.27). Increases in past-12-month prevalence were observed across ages, sexes, geographies, and among non-Hispanic White adults. Past-12-month and past-30-day prevalences increased during 2023-2024 among adults with no past-12-month smoking, never or former vaping, current smoking, with and without current alcohol or cannabis use, and without current other non-nicotine substance use (PRs range:1.53-3.10). No significant cross-year change was observed among those with current vaping, current other non-nicotine substance use, or recent-former smoking. Within-year comparisons showed higher 2024 past-12-month prevalence among young vs. older adults, males vs. females, non-Hispanic White vs. Black adults, individuals with vs. without recent smoking or vaping, and those with vs. without current non-nicotine substance use. Conclusion U.S. adult nicotine pouch use increased from 2023-2024 across sociodemographic and nicotine/tobacco use statuses. Further population-level surveillance and longitudinal research on use patterns are warranted.</p>","PeriodicalId":50805,"journal":{"name":"American Journal of Preventive Medicine","volume":" ","pages":"108393"},"PeriodicalIF":4.5,"publicationDate":"2026-04-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147787614","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Persistent sex differences in cardiovascular disease risk factors: a longitudinal cohort study in youth with type 1 diabetes.","authors":"Darja Šmigoc Schweiger, Zala Mlinarič, Maddalena Macedoni, Elisa Giani, Emil Plesnik, Tinka Hovnik, Primož Kotnik, Klemen Dovč, Nataša Bratina, Tadej Battelino, Urh Grošelj","doi":"10.1016/j.amepre.2026.108391","DOIUrl":"https://doi.org/10.1016/j.amepre.2026.108391","url":null,"abstract":"<p><strong>Introduction: </strong>Women with type 1 diabetes (T1D) experience a greater diabetes-related increase in cardiovascular disease (CVD) and mortality risk than men. This study aimed to examine early sex-related differences in CVD risk factors among youth with T1D.</p><p><strong>Methods: </strong>This study included 311 Slovenian participants aged 2-25 years who were enrolled between 2015 and 2016 (50.8% female; mean age, 12.66 ± 4.32 years; diabetes duration, 5.77 ± 3.77 years), clinically diagnosed with T1D for at least 1 year, and underwent annual assessments. A linear mixed model was used to analyze associations over a mean follow-up of 3.91 ± 1.72 years.</p><p><strong>Results: </strong>Females had persistently higher risk lipid profiles with higher total cholesterol, low-density lipoprotein cholesterol (LDL-C), non-high-density lipoprotein cholesterol (non-HDL-C), and apolipoprotein B (ApoB) levels (p < 0.001), higher high-sensitivity C-reactive protein levels (hsCRP) (p = 0.023), and greater multifactorial CVD risk (p = 0.04). High LDL-C and body mass index and low LDL/ApoB ratios were linked to increased hsCRP, whereas high insulin pump/sensor use was associated with decreased hsCRP (p = 0.008).</p><p><strong>Conclusions: </strong>Females exhibited persistently higher inflammation likely influenced by an unfavorable lipid profile and multiple CVD risk factors, highlighting the need for early, sex-specific CVD risk reduction strategies. Further research is needed to assess the long-term impact of these interventions.</p>","PeriodicalId":50805,"journal":{"name":"American Journal of Preventive Medicine","volume":" ","pages":"108391"},"PeriodicalIF":4.5,"publicationDate":"2026-04-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147787825","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Testing for Lipid Levels and Diabetes among Autistic Youth who are and are not Prescribed Anti-Psychotics: A Cohort Study.","authors":"Laura C Hart, Joseph Sirrianni, Steve Rust, Christopher Hanks","doi":"10.1016/j.amepre.2026.108389","DOIUrl":"https://doi.org/10.1016/j.amepre.2026.108389","url":null,"abstract":"<p><strong>Introduction: </strong>Autistic youth have higher rates of hyperlipidemia and diabetes than non-autistic youth and thus need age-appropriate monitoring for hyperlipidemia and diabetes. Little is known about how frequently autistic youth are monitored for these conditions.</p><p><strong>Methods: </strong>This analysis assessed monitoring for hyperlipidemia and diabetes among 230 autistic youth ages 16 to 30 years (113 were prescribed anti-psychotics, 117 were not) between January 2011 and May 2020. Outcomes assessed included the proportion of patients who had ANY testing for hyperlipidemia and diabetes in both groups, proportion of prescriptions monitored for hyperlipidemia and diabetes in the last year, and identification of patient factors associated with monitoring.</p><p><strong>Results: </strong>A significantly higher proportion of autistic youth prescribed anti-psychotics had testing for both hyperlipidemia and diabetes during the study period than autistic youth who were not (73% vs. 49%, p< 0.001). While most autistic youth who were prescribed anti-psychotics had some monitoring done, of the 1538 prescriptions for anti-psychotics (new and renewal) identified, 847 (55%) were considered unmonitored. Having other bloodwork done was significantly associated with higher odds of testing for hyperlipidemia or diabetes (OR 1.45, 95% CI [1.37, 1.56]), but not other factors assessed.</p><p><strong>Conclusions: </strong>Most autistic youth prescribed anti-psychotics in this cohort underwent some monitoring for hyperlipidemia and diabetes, but not at a level consistent with guidelines. Many autistic youth not prescribed anti-psychotics are not getting testing for hyperlipidemia or diabetes. Providers should consider adding lipid and diabetes testing to other bloodwork, as this was positively associated with monitoring in this analysis.</p>","PeriodicalId":50805,"journal":{"name":"American Journal of Preventive Medicine","volume":" ","pages":"108389"},"PeriodicalIF":4.5,"publicationDate":"2026-04-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147788021","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Impact of Layering Tobacco 21 Laws and Smoke-free Laws on US Adolescent Smoking Behaviors.","authors":"Steven Cook, Catherine A Vander Woude, Yanmei Xie, James H Buszkiewicz, Megan E Patrick, Michael R Elliott, Spruha Joshi, James F Thrasher, Nancy L Fleischer","doi":"10.1016/j.amepre.2026.108387","DOIUrl":"https://doi.org/10.1016/j.amepre.2026.108387","url":null,"abstract":"<p><strong>Introduction: </strong>Smoke-free and Tobacco 21 (T21) laws are complementary tobacco control strategies to reduce adolescent cigarette smoking. To test for policy layering, this study examined the impact of county-level T21 laws on adolescent smoking in counties with different smoke-free policy environments.</p><p><strong>Methods: </strong>This study used repeated cross-sectional data from the Monitoring the Future study (2014-2020) to examine interactions between county-level T21 coverage (<100% vs. 100%) and smoke-free workplace and hospitality law coverage (<100% vs. 100%) on past 30-day cigarette use, smoking initiation, and smoking intentions among 10^th (ages, 15-16 years) and 12^th (ages, 17-18 years) graders. Universal coverage was defined as 100% coverage for both T21 and smoke-free laws. Interaction terms were estimated using grade-stratified modified Poisson regression models, interpreted as marginal effects (ME) based on predicted probabilities.</p><p><strong>Results: </strong>Universal coverage was associated with a lower probability of cigarette smoking initiation among 10th graders (ME=-0.011, 95% CI=-0.037, -0.006), compared to counties with less than universal coverage for both T21 and smoke-free workplace laws. Among 12^th graders, universal coverage was associated with a lower probability of past 30-day cigarette use (workplace ME=-0.035, 95% CI=-0.054, -0.016; hospitality ME=-0.039, 95% CI=-0.060, -0.019), compared to counties with less than universal coverage.</p><p><strong>Conclusions: </strong>This study found that layering T21 law coverage with smoke-free workplace and hospitality law coverage was associated with lower adolescent smoking. While the patterns were not consistent among 10^th and 12^th graders for all smoking outcomes, the results suggest policy layering may be an effective tobacco control strategy to reduce adolescent smoking.</p>","PeriodicalId":50805,"journal":{"name":"American Journal of Preventive Medicine","volume":" ","pages":"108387"},"PeriodicalIF":4.5,"publicationDate":"2026-04-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147788174","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Performance of Large Language Models in Detecting Explicit and Implicit Colorism in Skin-Lightening Product Advertisements: A Validation Study.","authors":"Sook Ning Chua, Junjie Anderson Lu, Xiaokang Fu, Jill R Kavanaugh, S Bryn Austin","doi":"10.1016/j.amepre.2026.108379","DOIUrl":"https://doi.org/10.1016/j.amepre.2026.108379","url":null,"abstract":"","PeriodicalId":50805,"journal":{"name":"American Journal of Preventive Medicine","volume":" ","pages":"108379"},"PeriodicalIF":4.5,"publicationDate":"2026-04-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147724266","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Telehealth and Hybrid Service Use for Major Depression and Substance Use Disorders among U.S. Adults, 2022-2023.","authors":"Wenhua Lu, Yifan Liu, Anderson Sungmin Yoon","doi":"10.1016/j.amepre.2026.108382","DOIUrl":"https://doi.org/10.1016/j.amepre.2026.108382","url":null,"abstract":"<p><strong>Introduction: </strong>This study examined patterns of telehealth and hybrid service use (telehealth combined with outpatient or inpatient care) for major depressive episodes (MDEs) and substance use disorders (SUDs) among US adults.</p><p><strong>Methods: </strong>Pooled data from the 2022 and 2023 National Survey on Drug Use and Health (N = 92,233) were analyzed to examine trends and patterns in overall telehealth use and hybrid service use among adults with past-year MDEs and those with past-year SUDs, respectively. Bivariate analyses and survey-weighted multivariable logistic regression were conducted between December 2024 and May 2025.</p><p><strong>Results: </strong>Among adults with past-year MDEs, telehealth use remained stable at around 44% from 2022 to 2023, while outpatient care remained the most common treatment modality and increased from 46.1% to 50.0% (OR = 1.16, p < .05). Among adults with past-year SUDs, telehealth use increased nonsignificantly from 5.4% in 2022 to 6.2% in 2023. For MDEs, telehealth use was higher among females than males (AOR = 1.41, p < 0.001) and among those with Medicaid (AOR = 1.90, p < 0.001) or private insurance (AOR = 1.79, p < 0.001) compared with uninsured adults. Adults with MDE-related severe impairment were more likely to use telehealth overall (AOR = 1.55, p < 0.001) and hybrid care. For SUDs, adults living in small metropolitan areas had lower telehealth use than those in large metropolitan areas (AOR = 0.77, p < .05). Telehealth use was also higher among those with moderate (AOR=2.72, p<0.001) or severe SUDs (AOR=10.04, p<0.001) than those with mild SUDs.</p><p><strong>Conclusions: </strong>Telehealth and hybrid service use for MDEs and SUDs remained largely stable in the post-pandemic period. When integrated with in-person care, telehealth can help expand access to mental health and substance use treatment among US adults.</p>","PeriodicalId":50805,"journal":{"name":"American Journal of Preventive Medicine","volume":" ","pages":"108382"},"PeriodicalIF":4.5,"publicationDate":"2026-04-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147718959","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association of Life-Course Social Mobility with Cardiovascular Disease and Modifiable Risk Factors: Evidence from the Longitudinal Aging Study in India.","authors":"Imnameren Longkumer, Soohyeon Ko, Rohit Bhatia, Rockli Kim, S V Subramanian","doi":"10.1016/j.amepre.2026.108383","DOIUrl":"https://doi.org/10.1016/j.amepre.2026.108383","url":null,"abstract":"<p><strong>Introduction: </strong>Assessing cardiovascular disease (CVD) risk in relation to life-course socioeconomic position (SEP) may provide insights into social mobility patterns; however, to the authors' knowledge this association remains unexplored in India. While studies from high-income countries demonstrate an inverse association between life-course SEP and CVD, results from lower-income countries remain heterogeneous. This study examines the association between life-course social mobility, CVD and modifiable risk-factors among middle-aged and older Indians.</p><p><strong>Methods: </strong>This study utilized data from the Longitudinal Aging Study in India (2017-2018), a nationally representative cross-sectional study of adults aged ≥45 years. Based on SEP during childhood (family financial position) and adulthood (monthly per-capita expenditure; household assets), life-course social mobility was classified as consistently high, upward mobility, downward mobility, and consistently low. Associations were examined using regression models.</p><p><strong>Results: </strong>The analytical sample included 65,364 respondents. Social mobility patterns indicated 40.29% remained in consistently high-SEP, 19.32% in consistently low-SEP, while 19.57% experienced upward mobility and 20.82% downward mobility. Compared to consistently low-SEP, those in consistently high-SEP were associated with greater odds of congestive heart failure (adjusted odds ratio [aOR]=1.80 [95% CI: 1.21-2.69]), heart attack (aOR=1.70 [95% CI: 1.35-2.16]), abnormal heart rhythm (aOR=1.43 [95% CI: 1.05-1.94]), heart diseases (aOR=1.37 [95% CI: 1.15-1.63]), and composite CVD (aOR=1.23 [95% CI: 1.07-1.42]). Further, upward social mobility was associated with higher odds of all CVD outcomes except abnormal heart rhythm and stroke. Life-course social mobility also showed a graded association with hypertension, BMI, central adiposity, and diabetes. The positive associations persisted using adult asset-based social mobility, coarsened exact matching, and multiple sensitivity analyses with different SEP indicators.</p><p><strong>Conclusions: </strong>The findings suggest in settings undergoing rapid epidemiological transition like India, life-course social mobility may confer increased CVD risk, underscoring the importance of considering country-specific life-course socioeconomic processes in CVD prevention strategies.</p>","PeriodicalId":50805,"journal":{"name":"American Journal of Preventive Medicine","volume":" ","pages":"108383"},"PeriodicalIF":4.5,"publicationDate":"2026-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147718949","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Opioid Use During Pregnancy among Individuals with Disabilities.","authors":"Andi Camden, Susan B Brogly, Tara Gomes, Astrid Guttmann, Yona Lunsky, Isobel Sharpe, Hong Lu, Hilary K Brown","doi":"10.1016/j.amepre.2026.108366","DOIUrl":"https://doi.org/10.1016/j.amepre.2026.108366","url":null,"abstract":"<p><strong>Introduction: </strong>To investigate (1) prevalence and time trends in opioid use during pregnancy and (2) patterns of opioid use before and during pregnancy, among individuals with and without disabilities.</p><p><strong>Methods: </strong>This population-based cohort study in Ontario, Canada, included all pregnancies to individuals with physical only (N=133,371), sensory only (N=49,306), intellectual/developmental only (N=2,876), and multiple disabilities (N=11,195), and those without any disability (N=1,271,919), 2013-2021. Overall and annual prevalence of opioid use during pregnancy was estimated, and patterns of opioid use by type, timing, duration, and dose before and during pregnancy were described. Data were analyzed from 2024-2025.</p><p><strong>Results: </strong>Opioid use during pregnancy was more common among individuals with multiple (10.5%), intellectual/developmental (8.9%), and physical disabilities (8.3%), and similar in those with sensory disabilities (4.9%), compared with no disability (3.9%). From 2013-2021, prevalence decreased in individuals without a disability (4.6% to 3.0%), and among those with multiple (10.5% to 8.7%), intellectual/developmental (10.6% to 8.3%), physical (9.8% to 5.9%), and sensory (5.7% to 3.2%) disabilities. Short-term prescribed opioid use for pain was the most prevalent type used. Prevalence of prescribed opioid use was highest at 6 months preconception and decreased in the first trimester in all groups but remained higher among individuals with disabilities. Duration and dose were higher in individuals with disabilities compared to those without disabilities.</p><p><strong>Conclusions: </strong>Maternal disability was associated with higher use, longer duration, and higher dosages of opioids during pregnancy. This group could benefit from enhanced evidence-based preconception care, medication counseling, and non-pharmacologic pain management, where possible.</p>","PeriodicalId":50805,"journal":{"name":"American Journal of Preventive Medicine","volume":" ","pages":"108366"},"PeriodicalIF":4.5,"publicationDate":"2026-04-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147663385","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Blood Pressure Trends among Autistic Youth Transitioning to Adult Care: A Retrospective Cohort Study.","authors":"Laura C Hart, Carson Richardson, Christopher Hanks","doi":"10.1016/j.amepre.2026.108372","DOIUrl":"https://doi.org/10.1016/j.amepre.2026.108372","url":null,"abstract":"<p><strong>Introduction: </strong>Autistic people have higher rates of cardiovascular disease and its risk factors than non-autistic peers. Transition from pediatric to adult health care is associated with health challenges for autistic people and may exacerbate cardiovascular risk for this population. However, this has not been studied extensively. This study sought to evaluate the relationship between transition to adult health care and blood pressure in a cohort of autistic adolescents and young adults.</p><p><strong>Methods: </strong>This study used linked electronic medical record (EMR) data from pediatric and adult care from January 2011 to May 2020 for a cohort seen in a medical home for autistic youth to evaluate trends in blood pressures before and after the first visit in adult health care using a linear mixed model. Time-to-event analysis was used to determine the proportion of study subjects with two blood pressures meeting criteria for hypertension.</p><p><strong>Results: </strong>Linear mixed model results showed no immediate significant differences in systolic (-1.1 mmHg, 95% CI -3.5 to 1.2) or diastolic (0.47, 95% CI -1.2 to 2.2) blood pressure related to transition to adult health care. Time-to-event analysis showed that over half the cohort had at least two elevated blood pressures over the study period, with the mean time to event being 2.5 years.</p><p><strong>Conclusions: </strong>The transition to adult health care was not associated with an increase in blood pressure in this cohort. Nonetheless, many of the youth in this cohort may meet the clinical definition of hypertension and merit closer monitoring and possible treatment of hypertension.</p>","PeriodicalId":50805,"journal":{"name":"American Journal of Preventive Medicine","volume":" ","pages":"108372"},"PeriodicalIF":4.5,"publicationDate":"2026-04-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147663303","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}