Annals of Human BiologyPub Date : 2025-12-01Epub Date: 2025-03-06DOI: 10.1080/03014460.2025.2461145
Kelly M Searle, Dominique E Earland, Keeley Morris, Albino F Bibe, Vali Muhiro, Anísio Novela, João L Ferrão
{"title":"Household storm damage limits use of and access to insecticide treated bednets in Mozambique.","authors":"Kelly M Searle, Dominique E Earland, Keeley Morris, Albino F Bibe, Vali Muhiro, Anísio Novela, João L Ferrão","doi":"10.1080/03014460.2025.2461145","DOIUrl":"10.1080/03014460.2025.2461145","url":null,"abstract":"<p><strong>Background: </strong>Cyclone Idai was one of the most destructive cyclones in the Southern Hemisphere. Malaria prevention is not part of cyclone response, but housing damage has been shown to increase malaria risk.</p><p><strong>Aim: </strong>To assess the extent to which housing damage led to insecticide treated net (ITN) damage, thus compounding malaria risk.</p><p><strong>Subjects and methods: </strong>A cross-sectional survey was conducted in Sussundenga village. This analysis focused on household damage and ITN use in the aftermath of Cyclone Idai. Generalised estimating equations logistic regression models were used to identify factors associated with ITN use.</p><p><strong>Results: </strong>Thirty-five percent (104 of 296) of participants reported not sleeping under an ITN the previous night. Sixty-one percent (64 of 104) of participants who reported not sleeping under an ITN indicated lack of access as the reason why. Minor household damage was associated with 0.34 (95% CI: 0.15-0.78) times lower odds of ITN use and destruction was associated with 0.23 (95% CI: 0.11-0.50) times lower odds of ITN use.</p><p><strong>Conclusion: </strong>We found that even minor household damage was associated with 70% decreased odds of ITN use. As severe storms become more frequent due to climate change, this is an area for further research to assist malaria control programs in their success.</p>","PeriodicalId":50765,"journal":{"name":"Annals of Human Biology","volume":"52 1","pages":"2461145"},"PeriodicalIF":1.8,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143568685","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Genetic polymorphism of 15 STR <i>loci</i> in agropastoral communities from central-northern Chile and relationships with other South American populations.","authors":"Margarita Reyes-Madrid, Francisca Vásquez-Estay, Valentina Gutiérrez, Nicolás Montalva","doi":"10.1080/03014460.2025.2486156","DOIUrl":"https://doi.org/10.1080/03014460.2025.2486156","url":null,"abstract":"<p><strong>Background: </strong>The agropastoral communities of Coquimbo, Chile, are characterised by their goat herding-based livelihoods, admixed ancestry, and transhumant mobility.</p><p><strong>Aim: </strong>To explore the impact of these features on genetic diversity and interactions with neighbouring populations.</p><p><strong>Subjects and methods: </strong>Genotypic polymorphisms of 15 STRs were analysed in 466 individuals from 15 communities. Forensic parameters were estimated. Genetic structure was assessed using R<sub>ST,</sub> Nei's distances, MDS, dendrograms, and STRUCTURE, with 23 reference populations from Chile, South America and globally.</p><p><strong>Results: </strong>A total of 158 alleles were observed, with frequencies ranging from 0.0011 to 0.5172. <i>CSF1PO</i>, <i>D18S51</i>, and <i>Penta E</i> showed deviation from Hardy-Weinberg equilibrium. The panel demonstrated high forensic performance (combined power of discrimination CPD > 0.999999999, combined power of exclusion CPE = 0.99999713817). No clear genetic structure was found within the Coquimbo communities. Regionally, Coquimbo clustered with northern Chile and north-west Argentina. Globally, it resembled other South American admixed populations, slightly differentiated from those from other regions.</p><p><strong>Conclusions: </strong>The STRs analysed show high forensic potential, low genetic structure within the agropastoral communities, and important similarities with populations in northern Chile and north-west Argentina, supporting the relevance of trans-Andean mobility in shaping their genetic landscape.</p>","PeriodicalId":50765,"journal":{"name":"Annals of Human Biology","volume":"52 1","pages":"2486156"},"PeriodicalIF":1.2,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144025567","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Screen time and pubertal development: a systematic review and meta-analysis.","authors":"Erdenetuya Bolormaa, Yusra Mirghani Aljailani Fadhulalla, Hyun Jung Kim, Seung-Ah Choe","doi":"10.1080/03014460.2025.2577891","DOIUrl":"10.1080/03014460.2025.2577891","url":null,"abstract":"<p><strong>Background: </strong>Several mechanisms have been proposed to explain how screen time may affect pubertal development.</p><p><strong>Aim: </strong>To quantify the association between screen time exposure and timing of pubertal onset in children.</p><p><strong>Subjects and methods: </strong>We conducted a systematic review and random-effects meta-analysis of observational studies identified through PubMed, Embase, and the Cochrane Library up to 1 May 2025. Pooled odds ratios (ORs) for early or precocious puberty per additional hour of screen time and for categorical comparisons (≥ 2 vs < 2 h/day) were estimated, along with weighted mean differences (WMDs) in daily screen hours.</p><p><strong>Results: </strong>Of 1,284 unique records, 10 studies enrolling 97,898 children aged 2-19 years met inclusion criteria, most conducted in China. Each additional hour of screen exposure was associated with higher odds of early pubertal development (OR = 1.35; 95% CI = 1.05-1.73). The comparison of ≥ 2 vs < 2 h/day did not reach significance (1.07; 95% CI = 0.90-1.26). In girls, pooled ORs were 1.07 (95% CI = 0.84-1.37) for early puberty and 1.27 (95% CI = 0.85-1.90) for precocious puberty. Children experiencing early puberty spent on average 0.63 additional screen-hours per day compared with peers (WMD = 0.63 h; 95% CI = 0.24-1.02).</p><p><strong>Conclusions: </strong>Screen time is associated with pubertal onset in both boys and girls, although substantial heterogeneity and cross-sectional designs limit causal inference. Future longitudinal and experimental studies are needed to clarify underlying mechanisms and inform evidence-based guidelines for healthy pubertal development.</p>","PeriodicalId":50765,"journal":{"name":"Annals of Human Biology","volume":"52 1","pages":"2577891"},"PeriodicalIF":1.3,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145460150","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Development of disease-specific growth charts for Argentine Prader-Willi syndrome without growth hormone treatment.","authors":"Silvia Caino, Carolina Caminiti, Rocio Rabosto Moleón, Gabriela Krochik, Mariana Del Pino","doi":"10.1080/03014460.2025.2534345","DOIUrl":"https://doi.org/10.1080/03014460.2025.2534345","url":null,"abstract":"<p><strong>Background: </strong>Prader-Willi syndrome (PWS) is a complex genetic disorder characterised by infantile hypotonia, early-onset obesity, intellectual disability, hypopigmentation, small hands and feet, short stature, hypogonadism, and distinctive facial features.</p><p><strong>Aim: </strong>To generate and report growth curves for height, sitting height, hands and feet length for Argentine children with Prader-Willi syndrome (PWS) without growth hormone treatment.</p><p><strong>Subjects and methods: </strong>A total of 1174 anthropometric measures were obtained from 167 children (82 boys) aged 0-19 years attending Hospital Garrahan between 1992 and 2019. Standardised techniques were used in patients with molecularly confirmed PWS. The 3rd, 10th, 25th, 50th, 75th, 90th, and 97th percentiles were estimated using the LMS method, which adjusts for skewness. Height data were plotted for comparison with the 50th percentile of the Argentine general population and German PWS without growth hormone treatment.</p><p><strong>Results: </strong>Growth curves for height, sitting height, hands and feet length were developed from 169 children. Mean adult height was 145.3 cm in females (<i>n</i> = 88) and 153.2 cm in males (<i>n</i> = 81), which are 15.4 and 19.6 cm below the 50th percentile of the Argentine non-PWS population for girls and boys, respectively. Compared with German PWS, Argentine PWS references were 3.3 and 5.9 cm shorter in girls and boys, respectively. Mean sitting height was 9.03 cm in boys and 9.61 cm in girls, shorter than the Argentine non-PWS population.</p><p><strong>Conclusion: </strong>Differences in adult height between Argentine and German PWS references highlight the importance of local growth standards. Country-specific reference charts are essential tools for identifying growth-impacting conditions and monitoring response to therapy.</p>","PeriodicalId":50765,"journal":{"name":"Annals of Human Biology","volume":"52 1","pages":"2534345"},"PeriodicalIF":1.3,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144994463","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Annals of Human BiologyPub Date : 2025-12-01Epub Date: 2025-03-31DOI: 10.1080/03014460.2025.2482972
Thomas Waldhoer, Sylvia Kirchengast, Lin Yang
{"title":"The effect of birth month on body height of Austrian conscripts varies according to educational level.","authors":"Thomas Waldhoer, Sylvia Kirchengast, Lin Yang","doi":"10.1080/03014460.2025.2482972","DOIUrl":"10.1080/03014460.2025.2482972","url":null,"abstract":"<p><p>An association between birth month and height has been repeatedly described, but no consistent seasonal patterns can be observed. In this study, the significance of educational level as a modulating cofactor for the association between body height and birth month was analysed using an anonymous data set from 1,179,600 male conscripts born in Austria between 1971 and 2002. A distinct seasonal trend was observed. Conscripts born from June to December had shorter final body height than their counterparts born between January and May. In general, the effect of month of birth on final body height is very small. Considering socioeconomic co-factors, however, this effect was particularly noticeable for the highest and middle education classes, while the observed effect was small among the lowest education class. A low educational level seems to reduce the seasonal effect on growth and finally body height. Consequently, a clear seasonal effect in body height was observed in this Austrian population-based sample, socioeconomic stress factors, such as a low level of education, can reduce the seasonal effects.</p>","PeriodicalId":50765,"journal":{"name":"Annals of Human Biology","volume":"52 1","pages":"2482972"},"PeriodicalIF":1.2,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143754919","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Annals of Human BiologyPub Date : 2025-12-01Epub Date: 2025-08-12DOI: 10.1080/03014460.2025.2539259
Mei Chen, Yanru Hong, Peipei Huang, Junzhen Li, Lu Yin
{"title":"Measurement of deciduous molar crowns and arches using digital imaging technology in pre-school children from Xiamen, China.","authors":"Mei Chen, Yanru Hong, Peipei Huang, Junzhen Li, Lu Yin","doi":"10.1080/03014460.2025.2539259","DOIUrl":"https://doi.org/10.1080/03014460.2025.2539259","url":null,"abstract":"<p><strong>Background: </strong>Deciduous teeth are closely associated with the development of the permanent teeth, drawing concern and emphasis in dental restoration and endodontics. The deciduous teeth arches and crowns can serve as a clinical diagnostic reference that contributes to the manufacture of dental restoration and dental therapy.</p><p><strong>Aim: </strong>This study measured dimensions of deciduous molar teeth in pre-school children using digital imaging technology.</p><p><strong>Subjects and methods: </strong>From November to December 2023, a total of 121 digital models of pre-school (3-6 years old) children in Xiamen were obtained using a digital oral scanner. The data were derived from the 3-Shape software based on the measurements on the models.</p><p><strong>Results: </strong>There were sex differences in crown width of most deciduous teeth, but not in antimeres. There were also statistical differences in the following measurements: a) mesial-distal diameter of mandibular second deciduous molar; b) occlusal-gingival distance of the right first deciduous molar; c) the upper left first deciduous molar in different sex controls; and d) girls were all smaller than boys. There were statistical differences in maxillary and mandibular arch width at 3, 4, 5 and 6 years of age and in the maxillary arch length at different ages, but not in the mandibular arch length. There was no statistical difference in maxillary arch length between boys and girls, but a statistical difference in arch width was detected between boys and girls.</p><p><strong>Conclusion: </strong>Significant differences existed in deciduous molar crowns and arches between children of different ages and sexes.</p>","PeriodicalId":50765,"journal":{"name":"Annals of Human Biology","volume":"52 1","pages":"2539259"},"PeriodicalIF":1.3,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144823098","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Annals of Human BiologyPub Date : 2025-12-01Epub Date: 2025-02-18DOI: 10.1080/03014460.2025.2455698
Bilinda Straight, Charles E Hilton, Charles Owuor Olungah, Belinda L Needham, Erica Tyler, Lora Iannotti, Theodore Zava, Melanie A Martin, Eleanor Brindle
{"title":"Drought-compounded stress and immune function in Kenyan pastoralist boys and girls occupying contrasting climate zones.","authors":"Bilinda Straight, Charles E Hilton, Charles Owuor Olungah, Belinda L Needham, Erica Tyler, Lora Iannotti, Theodore Zava, Melanie A Martin, Eleanor Brindle","doi":"10.1080/03014460.2025.2455698","DOIUrl":"10.1080/03014460.2025.2455698","url":null,"abstract":"<p><strong>Background and aim: </strong>We provide ethnographic, photovoice, and psychosocial stress data (food and water insecurity, potentially traumatic events, stress biomarkers) documenting the joys, hazards, and stressors of adolescents engaging in climate-sensitive pastoralist livelihoods in a global climate change hot spot. We aim to holistically capture socio-environmental relationships characterised by climate sensitive livelihoods and forms of precarity exacerbated by climate change.</p><p><strong>Subjects and methods: </strong>Qualitative and quantitative methods were integrated to understand the embodied toll of hazards that Samburu pastoralists faced based on a sample of 161 young people. Quantitatively, we tested for associations of psychosocial stressors with both psychological distress and cell-mediated immune function (assessed through differences in IgG antibodies to Epstein-Barr virus).</p><p><strong>Results: </strong>Qualitatively, young Samburu reported drought, food and water insecurity, wildlife encounters, and war exposure. Girls overall endorsed more posttraumatic stress symptoms, although boys reported relatively more stressors; girls overall and young people in the hotter subregion manifested more immune dysregulation.</p><p><strong>Conclusion: </strong>In spite of important differences between climate subregions, the common elements throughout the Samburu pastoralist leanscape include food and water insecurity and overall precarity exacerbated by drought and climate change. Community-driven interventions are needed to reduce precarity for young people pursuing pastoralist livelihoods.</p>","PeriodicalId":50765,"journal":{"name":"Annals of Human Biology","volume":"52 1","pages":"2455698"},"PeriodicalIF":1.8,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11839180/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143442684","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Annals of Human BiologyPub Date : 2025-12-01Epub Date: 2025-05-27DOI: 10.1080/03014460.2025.2494565
Carla Santos, Alcibíades Bustamante, José Maia, Olga Vasconcelos, Go Tani, Donald Hedeker, Peter T Katzmarzyk, Sara Pereira
{"title":"Secular trends in BMI, excess weight and body fat skinfolds in Peruvian children living at high altitude.","authors":"Carla Santos, Alcibíades Bustamante, José Maia, Olga Vasconcelos, Go Tani, Donald Hedeker, Peter T Katzmarzyk, Sara Pereira","doi":"10.1080/03014460.2025.2494565","DOIUrl":"10.1080/03014460.2025.2494565","url":null,"abstract":"<p><strong>Background: </strong>There is limited evidence on secular trends in adiposity among high-altitude children.</p><p><strong>Aims: </strong>To describe secular trends in body mass index (BMI), excess weight and body fat skinfolds (SKF) among Peruvian children living at high altitude and to investigate the risk for excess weight in 2019 relative to 2009.</p><p><strong>Subjects and methods: </strong>We sampled 1585 Peruvians aged 6-11 years from the Junín region. Height and weight were measured, and BMI was calculated. WHO cut-offs were used to classify children by weight status. The sum of SKF was used for analysis. BMI and sum SKF were log-transformed. Two-factor ANOVA and post-hoc contrasts were used together with trend plots for BMI<sub>log</sub> and SKF<sub>log</sub>. Relative risks for excess weight were estimated with 95% confidence intervals. All analyses were done in STATA.</p><p><strong>Results: </strong>BMI<sub>log</sub> and SKF<sub>log</sub> means increased in both sexes from 2009 to 2019, with age-specific variation. Between 2009 and 2019, BMI values shifted from near P50 to P75 on WHO percentiles for both sexes in most age groups. The risk of excess weight was not significantly higher for most children in 2019 compared to 2009.</p><p><strong>Conclusions: </strong>Positive secular trends in BMI<sub>log</sub> and SKF<sub>log</sub> were observed, with significant increases at specific ages.</p>","PeriodicalId":50765,"journal":{"name":"Annals of Human Biology","volume":"52 1","pages":"2494565"},"PeriodicalIF":1.3,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144152766","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Annals of Human BiologyPub Date : 2025-12-01Epub Date: 2025-09-17DOI: 10.1080/03014460.2025.2551531
Tingting Zhang, Yingli Si, Xiangyu Wang
{"title":"Comparative effects of growth hormone, testosterone, and aromatase inhibitors on height gain in children and adolescents with idiopathic short statures: a network meta-analysis.","authors":"Tingting Zhang, Yingli Si, Xiangyu Wang","doi":"10.1080/03014460.2025.2551531","DOIUrl":"10.1080/03014460.2025.2551531","url":null,"abstract":"<p><strong>Background: </strong>Idiopathic short stature (ISS) is defined as height more than two standard deviations below the mean for age and sex, without an identifiable pathological cause. Pharmacologic options such as growth hormone (GH), testosterone, and aromatase inhibitors (AIs) have been studied for their potential to promote height gain in affected children and adolescents.</p><p><strong>Aim: </strong>To compare the efficacy of GH, testosterone, and AIs in promoting height gain in children and adolescents with ISS, considering both individual and combination treatments using a network meta-analysis.</p><p><strong>Subjects and methods: </strong>This meta-analysis was conducted in accordance with the PRISMA 2020 guidelines. A systematic search was performed across PubMed, Embase, Web of Science, Google Scholar, Semantic Scholar, and ResearchRabbit. Eligible studies were selected on the basis of predefined inclusion criteria. Standardised mean differences (SMDs) and 95% confidence intervals (CIs) were calculated. Heterogeneity was assessed <i>via</i> the chi-square test and <i>I</i><sup>2</sup> index. Publication bias was evaluated <i>via</i> funnel plots and Egger's test.</p><p><strong>Results: </strong>All the treatment groups (GH, anastrozole, letrozole, AI+GH) demonstrated significantly greater height gains than did the placebo group. Letrozole was associated with the greatest increase in height (SMD = 0.83, 95% CI = 0.38-1.28). No statistically significant differences were observed among the active treatments. Oxandrolone did not significantly differ from the placebo (SMD = 0.52, 95% CI = -0.03-1.07).</p><p><strong>Conclusion: </strong>GH, AIs, and combination therapies improve height in children and adolescents with ISS, with letrozole showing a modest advantage but no clear superiority, highlighting the need for individualised treatment.</p>","PeriodicalId":50765,"journal":{"name":"Annals of Human Biology","volume":"52 1","pages":"2551531"},"PeriodicalIF":1.3,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145076573","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Annals of Human BiologyPub Date : 2025-12-01Epub Date: 2025-03-17DOI: 10.1080/03014460.2025.2472757
Ruta Morkuniene, Tim J Cole, Ruta Levuliene, Andrej Suchomlinov, Janina Tutkuviene
{"title":"The associations of preterm birth and low birth weight with childhood growth curves between birth and 12 years: a SITAR-based longitudinal analysis.","authors":"Ruta Morkuniene, Tim J Cole, Ruta Levuliene, Andrej Suchomlinov, Janina Tutkuviene","doi":"10.1080/03014460.2025.2472757","DOIUrl":"10.1080/03014460.2025.2472757","url":null,"abstract":"<p><strong>Background: </strong>Children born preterm grow differently from those born at term.</p><p><strong>Aim: </strong>To compare growth in length/height, weight, and BMI of preterm- and term-born children, grouped by birth weight (BW) and gestational age (GA).</p><p><strong>Subjects and methods: </strong>Longitudinal data of 950 children (birth to 12 years) were collected retrospectively. Growth trajectories were modelled using SITAR (Superimposition by Translation and Rotation) by sex, with three groups each for GA and BW.</p><p><strong>Results: </strong>SITAR summarised growth patterns from birth to 12 years and explained 76-79% of height variance, 90-92% for weight, and 72-75% for BMI. Early preterm and low BW groups were shorter, lighter and thinner on average than their term or normal BW peers, with late preterm and low-normal BW groups intermediate. Effects were larger for BW than GA, e.g. early preterm girls/boys were 0.3/0.8 kg lighter, 0.9/0.9 cm shorter and 0.8/0.8 kg/m<sup>2</sup> thinner, while low BW girls/boys were 0.5/1.0 kg lighter, 1.5/1.4 cm shorter and 0.8/0.9 kg/m<sup>2</sup> thinner. Moreover, faster growth rates were associated with lower BW.</p><p><strong>Conclusion: </strong>Both BW and GA significantly impacted growth, but low BW more so than early preterm birth. This underscores the need for targeted interventions for low BW children to address potential long-term growth challenges.</p>","PeriodicalId":50765,"journal":{"name":"Annals of Human Biology","volume":"52 1","pages":"2472757"},"PeriodicalIF":1.2,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143651753","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}